Development of a classifier for [18F]fluorodeoxyglucose extravasation severity using semi-quantitative readings from topically applied detectors
Radiotracer extravasations, caused largely by faulty tracer injections, can occur in up to 23% of 18F-fluorodeoxyglucose (FDG) PET/CT scans and negatively impact radiological review and tracer quantification. Con... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 14, 2022 Category: Radiology Authors: Steve Perrin, Jackson W. Kiser, Josh Knowland and Spencer L. Bowen Tags: Original research Source Type: research

Motion correction and its impact on quantification in dynamic total-body 18F-fluorodeoxyglucose PET
The total-body positron emission tomography (PET) scanner provides an unprecedented opportunity to scan the whole body simultaneously, thanks to its long axial field of view and ultrahigh temporal resolution. ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 14, 2022 Category: Radiology Authors: Tao Sun, Yaping Wu, Wei Wei, Fangfang Fu, Nan Meng, Hongzhao Chen, Xiaochen Li, Yan Bai, Zhenguo Wang, Jie Ding, Debin Hu, Chaojie Chen, Zhanli Hu, Dong Liang, Xin Liu, Hairong Zheng & hellip; Tags: Original research Source Type: research

Comparison between a dual-time-window protocol and other simplified protocols for dynamic total-body 18F-FDG PET imaging
Efforts have been made both to avoid invasive blood sampling and to shorten the scan duration for dynamic positron emission tomography (PET) imaging. A total-body scanner, such as the uEXPLORER PET/CT, can rel... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 14, 2022 Category: Radiology Authors: Zhenguo Wang, Yaping Wu, Xiaochen Li, Yan Bai, Hongzhao Chen, Jie Ding, Chushu Shen, Zhanli Hu, Dong Liang, Xin Liu, Hairong Zheng, Yongfeng Yang, Yun Zhou, Meiyun Wang and Tao Sun Tags: Original research Source Type: research

Clinical validation of a population-based input function for 20-min dynamic whole-body 18F-FDG multiparametric PET imaging
Contemporary PET/CT scanners can use 70-min dynamic whole-body (D-WB) PET to generate more quantitative information about FDG uptake than just the SUV by generating parametric images of FDG metabolic rate (MRFDG)... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 8, 2022 Category: Radiology Authors: Andr é H. Dias, Anne M. Smith, Vijay Shah, David Pigg, Lars C. Gormsen and Ole L. Munk Tags: Original research Source Type: research

Comparison of image quality and spatial resolution between 18F, 68Ga, and 64Cu phantom measurements using a digital Biograph Vision PET/CT
PET nuclides can have a considerable influence on the spatial resolution and image quality of PET/CT scans, which can influence diagnostics in oncology, for example. The individual impact of the positron energ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 5, 2022 Category: Radiology Authors: Anja Braune, Liane Oehme, Robert Freudenberg, Frank Hofheinz, J örg van den Hoff, Jörg Kotzerke and Sebastian Hoberück Tags: Original research Source Type: research

Towards accurate partial volume correction in 99mTc oncology SPECT: perturbation for case-specific resolution estimation
Currently, there is no consensus on the optimal partial volume correction (PVC) algorithm for oncology imaging. Several existing PVC methods require knowledge of the reconstructed resolution, usually as the po... (Source: EJNMMI Physics)
Source: EJNMMI Physics - September 5, 2022 Category: Radiology Authors: Rebecca Gillen, Kjell Erlandsson, Ana M. Denis-Bacelar, Kris Thielemans, Brian F. Hutton and Sarah J. McQuaid Tags: Original research Source Type: research

Improved accuracy of S-value-based dosimetry: a guide to transition from Cristy –Eckerman to ICRP adult phantoms
In 2016, the International Commission on Radiological Protection (ICRP) published the results of Monte Carlo simulations performed using updated and anatomically realistic voxelized phantoms. The resulting spe... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 26, 2022 Category: Radiology Authors: Shalini Subramanian, Bin He, Eric Frey, Derek W. Jokisch, Wesley Bolch and George Sgouros Tags: Original research Source Type: research

Positron range in combination with point-spread-function correction: an evaluation of different implementations for [124I]-PET imaging
To evaluate the effect of combining positron range correction (PRC) with point-spread-function (PSF) correction and to compare different methods of implementation into iterative image reconstruction for 124I-PET ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 19, 2022 Category: Radiology Authors: Hunor Kert ész, Maurizio Conti, Vladimir Panin, Jorge Cabello, Deepak Bharkhada, Thomas Beyer, Laszlo Papp, Walter Jentzen, Jacobo Cal-Gonzalez, Joaquín L. Herraiz, Alejandro López-Montes and Ivo Rausch Tags: Original research Source Type: research

Impact of the dead-time correction method on quantitative 177Lu-SPECT (QSPECT) and dosimetry during radiopharmaceutical therapy
Dead-time correction is required for accurate quantitative SPECT-based dosimetry in the context of personalised 177Lu radiopharmaceutical therapy. We aimed to evaluate the impact of applying dead-time correction ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 17, 2022 Category: Radiology Authors: Alessandro Desy, Guillaume F. Bouvet, Nancy Lafreni ère, Atefeh Zamanian, Philippe Després and Jean-Mathieu Beauregard Tags: Short communication Source Type: research

A deep learning-based whole-body solution for PET/MRI attenuation correction
Deep convolutional neural networks have demonstrated robust and reliable PET attenuation correction (AC) as an alternative to conventional AC methods in integrated PET/MRI systems. However, its whole-body impl... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 17, 2022 Category: Radiology Authors: Sahar Ahangari, Anders Beck Olin, Marianne Kingg ård Federspiel, Bjoern Jakoby, Thomas Lund Andersen, Adam Espe Hansen, Barbara Malene Fischer and Flemming Littrup Andersen Tags: Original research Source Type: research

Convolutional neural networks for automatic image quality control and EARL compliance of PET images
Machine learning studies require a large number of images often obtained on different PET scanners. When merging these images, the use of harmonized images following EARL-standards is essential. However, when ... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 9, 2022 Category: Radiology Authors: Elisabeth Pfaehler, Daniela Euba, Andreas Rinscheid, Otto S. Hoekstra, Josee Zijlstra, Joyce van Sluis, Adrienne H. Brouwers, Constantin Lapa and Ronald Boellaard Tags: Original research Source Type: research

Quantitative SPECT/CT imaging of lead-212: a phantom study
Lead-212 (212Pb) is a promising radionuclide for targeted therapy, as it decays to α-particle emitter bismuth-212 (212Bi) via β-particle emission. This extends the problematic short half-life of 212Bi. In prepara... (Source: EJNMMI Physics)
Source: EJNMMI Physics - August 4, 2022 Category: Radiology Authors: Monika Kvassheim, Mona-Elisabeth R. Revheim and Caroline Stokke Tags: Original research Source Type: research

Verification of the effect of acquisition time for SwiftScan on quantitative bone single-photon emission computed tomography using an anthropomorphic phantom
SwiftScan single-photon emission computed tomography (SPECT) is a recently released scanning technique with data acquired when the detector is stationary and when it moves from one view to the next. The influe... (Source: EJNMMI Physics)
Source: EJNMMI Physics - July 30, 2022 Category: Radiology Authors: Takuro Shiiba, Yuya Sekikawa, Shinji Tateoka, Nobutaka Shinohara, Yuuki Inoue, Yasuyoshi Kuroiwa, Takashi Tanaka, Yasushi Kihara and Takuroh Imamura Tags: Short communication Source Type: research

Towards personalised dosimetry in patients with liver malignancy treated with 90Y-SIRT using in vivo-driven radiobiological parameters
The prediction of response is one of the major challenges in radiation-based therapies. Although the selection of accurate linear –quadratic model parameters is essential for the estimation of radiation respons... (Source: EJNMMI Physics)
Source: EJNMMI Physics - July 30, 2022 Category: Radiology Authors: Yaser H. Gholami, Kathy P. Willowson and Dale L. Bailey Tags: Original research Source Type: research

DeepPVC: prediction of a partial volume-corrected map for brain positron emission tomography studies via a deep convolutional neural network
Partial volume correction with anatomical magnetic resonance (MR) images (MR-PVC) is useful for accurately quantifying tracer uptake on brain positron emission tomography (PET) images. However, MR segmentation... (Source: EJNMMI Physics)
Source: EJNMMI Physics - July 30, 2022 Category: Radiology Authors: Keisuke Matsubara, Masanobu Ibaraki and Toshibumi Kinoshita Tags: Original research Source Type: research