A Study on the Status of Proton Pump Inhibitor Prescriptions Using Diagnosis Procedure Combination Data in Japan
Conclusion: PPI use has increased substantially in hospitalized patients. The prevalence of PPI prescription by doctors other than gastroenterologists also increased.Digestion (Source: Digestion)
Source: Digestion - March 7, 2019 Category: Gastroenterology Source Type: research
Endoscopic Detachable Snare Ligation Improves the Treatment for Colonic Diverticular Hemorrhage
Conclusion: The results of this study suggest that EDSL is superior to EC as treatment for colonic diverticular hemorrhage. EDSL may provide improvements in the clinical course of patients with colonic diverticular hemorrhage.Digestion (Source: Digestion)
Source: Digestion - March 7, 2019 Category: Gastroenterology Source Type: research
Chenodeoxycholic Acid Releases Proinflammatory Cytokines from Small Intestinal Epithelial Cells Through the Farnesoid X Receptor
Conclusions: FXR expression was elevated at the terminal ileum in IBS patients. CDCA increased proinflammatory cytokines, while guggulsterone blocked these increases.Digestion (Source: Digestion)
Source: Digestion - March 7, 2019 Category: Gastroenterology Source Type: research
Effects of L-Menthol and Carbon Dioxide on the Adenoma Detection Rate during Colonoscopy: L-Menthol and Carbon Dioxide on Colonoscopy
Conclusions: The fact that CO2I was associated with significant decreases in the ADR was a problem. The combined use of L-mentholS and CO2I could help to suppress the decrease in the ADR.Digestion (Source: Digestion)
Source: Digestion - March 7, 2019 Category: Gastroenterology Source Type: research
Comparisons of the Mucosal Healing Process between Flat and Protruded Type after Endoscopic Submucosal Dissection for Gastric Neoplasms
Conclusions: The healing type of mucosal ulceration after ESD seemed to be influenced by location, specimen size, and the presence of anH. pylori infection.Digestion (Source: Digestion)
Source: Digestion - February 22, 2019 Category: Gastroenterology Source Type: research
Long-Term Outcomes after Surgical Resection for Synchronous or Metachronous Hepatic and Pulmonary Colorectal Cancer Metastases
Conclusions: Surgical resection of both hepatic and pulmonary metastases of CRC represents a safe and effective treatment. It might lead to rewarding long-term survival rates in high selected patients. Shorter DFIs between first metastasectomy and diagnosis of second metastases can determine worse prognoses. In addition, poor outcomes could be predicted also for patients affected by synchronously detected pulmonary CRC metastases, although further confirmatory analyses are strongly required.Digestion (Source: Digestion)
Source: Digestion - February 15, 2019 Category: Gastroenterology Source Type: research
A Nondilated Main Pancreatic Duct Predicts Type 2 Autoimmune Pancreatitis: Comparative Study of Resected Pancreatic Head Masses
Conclusions: In the setting of undetermined pancreatic focal mass, a nondilated MPD suggests the diagnosis of type 2 AIP.Digestion (Source: Digestion)
Source: Digestion - February 14, 2019 Category: Gastroenterology Source Type: research
Loss of RUNX3 Immunoreactivity in Non-Neoplastic Rectal Mucosa May Predict the Occurrence of Ulcerative Colitis-Associated Colorectal Cancer
Conclusion: RUNX3 immunostaining of non-neoplastic mucosa is useful for identifying UC patients at a high risk of developing CAC.Digestion (Source: Digestion)
Source: Digestion - February 14, 2019 Category: Gastroenterology Source Type: research
Metabolic Endoscopy: Development and Perspectives
This article will therefore highlight procedures with data on type 2 d iabetes mellitus (T2DM) as the most prominent component of the metabolic syndrome.Summary: Most procedures showed beneficial effects in terms of weight reduction. For gastric procedures, there were no systematic studies primarily addressing parameters of glucose metabolism or diabetes outcomes. Metabolic benefit, if there is any, is most likely a by-product of weight loss. By contrast, duodenal-jejunal bypass sleeve (DJBS) is conceptually an antidiabetic procedure. Although adverse events are frequent, recent data points to a positive benefit-risk ratio...
Source: Digestion - February 7, 2019 Category: Gastroenterology Source Type: research
Mucosa-Associated Microbiota in the Gastrointestinal Tract of Healthy Japanese Subjects
Conclusions: The MAM profiles of the upper and lower gut were significantly different. The inter-individual differences in MAM were remarkable compared to the intra-individual differences.Digestion (Source: Digestion)
Source: Digestion - February 6, 2019 Category: Gastroenterology Source Type: research
Predictive Factors for Rebleeding after Negative Capsule Endoscopy among Patients with Overt Obscure Gastrointestinal Bleeding
Conclusions: Rebleeding is not a rare condition among patients with overt OGIB after negative CE. Patients with ongoing overt OGIB or severe anemia at the initial CE examination seem to have a higher risk of rebleeding.Digestion (Source: Digestion)
Source: Digestion - February 1, 2019 Category: Gastroenterology Source Type: research
MR Defecography in Assessing Functional Defecation Disorder: Diagnostic Value of the Defecation Phase in Detection of Dyssynergic Defecation and Pelvic Floor Prolapse in Females
Conclusion: The straining phase and the defecation phase have the same ability in assessing paradoxical puborectalis contraction of the DD. Compared with the straining phase, the defecation phase provides the maximum stress to the pelvic floor resulting in complete levator ani relaxation. In addition to diagnosing the abnormal anorectal function, the defecation phase with the discharge of the rectal filling demonstrates maximum anterior/middle pelvic organ descent in DD patients.Digestion (Source: Digestion)
Source: Digestion - January 31, 2019 Category: Gastroenterology Source Type: research
Erratum
Digestion (Source: Digestion)
Source: Digestion - January 28, 2019 Category: Gastroenterology Source Type: research
Guidelines for Colonic Diverticular Bleeding and Colonic Diverticulitis: Japan Gastroenterological Association
Colonic diverticular disease has been increasing in prevalence in Japan due to the rapidly aging population. Colonic diverticular bleeding can result in hemorrhagic shock requiring blood transfusion, and it carries a high risk of recurrence within 1 year. Colonic diverticulitis can cause abscess, fistula formation, and perforation of the colon that may require surgery, and it often recurs. As a result, patients with colonic diverticular disease are often bothered by required frequent examinations, re-hospitalization, and a consequent decrease in quality of life. However, the management of diverticular disease differs betwe...
Source: Digestion - January 13, 2019 Category: Gastroenterology Source Type: research
