Current Status of < b > < i > Helicobacter pylori < /i > < /b > Diagnosis and Eradication Therapy in Japan Using a Nationwide Database
Conclusions: Diagnostic tests ofH.  pylori infection mostly followed Japanese Society forHelicobacter Research guidance, although some antibody measurements were timed inappropriately. Vonoprazan appears to increase the success rate of primary therapy.Digestion (Source: Digestion)
Source: Digestion - June 19, 2019 Category: Gastroenterology Source Type: research

Validation of Asia-Pacific Colorectal Screening Score for Asymptomatic Participants and Outpatients in Northwest District of China
Conclusion: APCS score is an effective method for ACRN screening in asymptomatic and also the outpatient subjects. Individuals with HR scores should be given priority for colonoscopy.Digestion (Source: Digestion)
Source: Digestion - June 14, 2019 Category: Gastroenterology Source Type: research

The Traditional Medicine Banhasasim-Tang Depolarizes Pacemaker Potentials of Cultured Interstitial Cells of Cajal through M3 Muscarinic and 5-HT3 Receptors in Murine Small Intestine
Conclusion: These results suggested that BHSST depolarizes the pacemaker potentials of ICCs in a dose-dependent manner through the M3 and 5-HT3 receptors via internal and external Ca2+-dependent and TRPM7- and ANO1-independent pathways in vitro. Moreover, BHSST increased ITR% in vivo in normal mice and GMD mouse models. Taken together, the results of this study showed that BHSST had the potential for development as a prokinetic agent in GI motility function.Digestion (Source: Digestion)
Source: Digestion - June 11, 2019 Category: Gastroenterology Source Type: research

Physicians ’ Knowledge and Application of Immunization Strategies in Patients with Inflammatory Bowel Disease: A Survey of the Italian Group for the Study of Inflammatory Bowel Disease
Conclusions: Efforts carried out by the scientific societies are required to increase the awareness of this relevant topic among physicians.Digestion (Source: Digestion)
Source: Digestion - June 5, 2019 Category: Gastroenterology Source Type: research

Contents Vol. 99, 2019
Digestion 2019;99:I –IV (Source: Digestion)
Source: Digestion - May 28, 2019 Category: Gastroenterology Source Type: research

Efficacy of Vonoprazan for 48-Week Maintenance Therapy of Patients with Healed Reflux Esophagitis
Conclusion: VPZ 10 mg is clinically effective for maintenance of healed RE for 48 weeks.Digestion (Source: Digestion)
Source: Digestion - May 24, 2019 Category: Gastroenterology Source Type: research

Poor Prognosis of Advanced Cholangiocarcinoma: Real-World Data from a Tertiary Referral Center
Conclusion: Prognosis in advanced stage CCA is still very poor. However, multimodal treatment in palliative patients significantly prolong survival.Digestion (Source: Digestion)
Source: Digestion - May 24, 2019 Category: Gastroenterology Source Type: research

Propofol Sedation in the Endoscopy Room versus Operation Room during Endoscopic Submucosal Dissection for Gastric Tumors: A Propensity Score-Matching Analysis
Conclusion: Sedation with propofol in the operation room might be required to ensure safer application of ESD for gastric tumors. However, a decrease in the desaturation rate was the only disadvantage of sedation in the endoscopy room.Digestion (Source: Digestion)
Source: Digestion - May 24, 2019 Category: Gastroenterology Source Type: research

Increasing Heme Oxygenase-1-Expressing Macrophages Indicates a Tendency of Poor Prognosis in Advanced Colorectal Cancer
Conclusion: In this study, the correlation between HO-1-expressing macrophages and clinicopathological parameters in the tumor microenvironment of colorectal cancer was studied for the first time, and the expression was associated with lymph node metastasis and shortening of DFS.Digestion (Source: Digestion)
Source: Digestion - May 21, 2019 Category: Gastroenterology Source Type: research

Long Noncoding RNA LINC00265 Promotes Glycolysis and Lactate Production of Colorectal Cancer through Regulating of miR-216b-5p/TRIM44 Axis
Conclusion: Our study highlighted the contribution of LINC00265/miR-216b-5p/TRIM44 signaling axis in CRC.Digestion (Source: Digestion)
Source: Digestion - May 10, 2019 Category: Gastroenterology Source Type: research

Efficacy of Endoscopic Evaluation of Acute Radiation Esophagitis during Chemoradiotherapy with Proton Beam Therapy Boost for Esophageal Cancer
Conclusion: Endoscopic evaluation of radiation esophagitis using FARE grades was safely performed and useful for adjusting added radiation to ensure the safety of escalations in CRT with PBT boost for esophageal cancer.Digestion (Source: Digestion)
Source: Digestion - May 8, 2019 Category: Gastroenterology Source Type: research

Effects of Proton Pump Inhibitor on the Distribution of < b > < i > Helicobacter pylori < /i > < /b > and Associated Gastritis in Patients with Gastric Atrophy
Conclusion: PPI treatment decreasedH. pylori both in the antrum and the corpus in patients with atrophic gastritis. Antral gastritis improved during PPI treatment, whereas no changes were found in the corpus.Digestion (Source: Digestion)
Source: Digestion - May 8, 2019 Category: Gastroenterology Source Type: research

Timing and Predictors of Recurrence of Dyspepsia Symptoms after Cessation of Acotiamide Therapy for Functional Dyspepsia: A Long-Term Observational Study
Conclusions: Dyspepsia symptoms recur about one year after cessation of acotiamide therapy. Patients with overlapped-type dyspepsia should be carefully followed after cessation. Patients should consult their treating physician before stopping acotiamide.Digestion (Source: Digestion)
Source: Digestion - May 7, 2019 Category: Gastroenterology Source Type: research

Does the 5-Aminosalicylate Concentration Correlate with the Efficacy of Oral 5-Aminosalicylate and Predict Response in Patients with Inflammatory Bowel Disease? A Systematic Review
Conclusions: An increase of the mucosal 5-ASA concentrations was observed during remission in patients with UC. No clear relationship between the faecal 5-ASA excretion and the therapeutic efficacy was identified.Digestion (Source: Digestion)
Source: Digestion - April 24, 2019 Category: Gastroenterology Source Type: research

A Potassium-Competitive Acid Blocker-Based Regimen as Second-Line Therapy Improves < b > < i > Helicobacter pylori < /i > < /b > Eradication
Conclusions: PCAB-based second-lineH. pylori eradication is significantly better than PPI-based therapy.Digestion (Source: Digestion)
Source: Digestion - April 16, 2019 Category: Gastroenterology Source Type: research