Predictors for Complicated Disease Course after Stepping Down from Combination to Antitumor Necrosis Factor Alpha Monotherapy in Children with Inflammatory Bowel Disease
Conclusion: Stepping down to anti-TNF α monotherapy may be related to lower anti-TNFα levels and to a more complicated disease course thereafter. Predictors for a complicated course were identified.Digestion (Source: Digestion)
Source: Digestion - January 13, 2019 Category: Gastroenterology Source Type: research

Preliminaries
Digestion 2019;99(suppl 1):I –II (Source: Digestion)
Source: Digestion - January 13, 2019 Category: Gastroenterology Source Type: research

Characteristics and Predictive Factor of < b > < i > Helicobacter pylori < /i > < /b > -Associated Functional Dyspepsia in Japanese Patients
Conclusion: HP eradication is an effective initial therapy for FD. PG II value is considered a predictive factor for FD symptom improvement through HP eradication.Digestion (Source: Digestion)
Source: Digestion - January 13, 2019 Category: Gastroenterology Source Type: research

Clinical Course of Chronic Pancreatitis in Elderly Patients
Conclusion: In elderly-CP, the course of disease significantly differs from non-elderly-CP. Therefore, individualized monitoring strategies for elderly-CP might be necessary.Digestion (Source: Digestion)
Source: Digestion - January 13, 2019 Category: Gastroenterology Source Type: research

Long-Term Prognosis of Patients with Obscure Gastrointestinal Bleeding: A Retrospective Cohort Study
Conclusions: Patients with OGIB showed a poor prognosis, especially those who were elderly or who had liver cirrhosis.Digestion (Source: Digestion)
Source: Digestion - January 13, 2019 Category: Gastroenterology Source Type: research

Oral Litholysis in Patients with Chronic Calcific Pancreatitis Unresponsive to or Ineligible for Extracorporeal Shock Wave Lithotripsy and Endoscopic Therapy
Conclusion: Oral litholysis using trimethadione may represent a noninvasive and effective complementary treatment in patients with CCP unresponsive to or ineligible for ESWL and endoscopic therapy.Digestion (Source: Digestion)
Source: Digestion - January 3, 2019 Category: Gastroenterology Source Type: research

pH-Dependent 5-Aminosalicylates Releasing Preparations Do Not Affect Thiopurine Metabolism
Conclusion: Our study revealed that time-dependent but not pH-dependent 5-ASA decreases the 6-MMP/6-TGN ratio. We also confirmed that concomitant allopurinol results in a low 6-MMP/6TGN ratio.Digestion (Source: Digestion)
Source: Digestion - January 2, 2019 Category: Gastroenterology Source Type: research

A Novel Predictive Nomogram for Early Endoscopic Recurrence after Intestinal Resection for Crohn ’s Disease
Conclusion: We developed a novel predictive nomogram for early ER after intestinal resection for CD. This prediction model might assist clinicians in managing patients with CD after an intestinal resection. Additional validation studies are currently being developed.Digestion (Source: Digestion)
Source: Digestion - January 2, 2019 Category: Gastroenterology Source Type: research

Title Page/Table of Contents
Digestion 2019;99:1 –4 (Source: Digestion)
Source: Digestion - December 18, 2018 Category: Gastroenterology Source Type: research

Author Index Vol. 99, No.1, 2019
Digestion 2019;99:120 –120 (Source: Digestion)
Source: Digestion - December 18, 2018 Category: Gastroenterology Source Type: research

Subject Index Vol. 99, No. 1, 2019
Digestion 2019;99:121 –121 (Source: Digestion)
Source: Digestion - December 18, 2018 Category: Gastroenterology Source Type: research

JGA News
Digestion 2019;99:122 –122 (Source: Digestion)
Source: Digestion - December 17, 2018 Category: Gastroenterology Source Type: research

Liquid Biopsy for the Management of Patients with Colorectal Cancer
Background: Liquid biopsy is a collective term that refers to the analysis of tumor-derived biomarkers isolated from biological fluids of cancer patients. Recently, many authors reported the usefulness of liquid biopsy for the management of malignancy.Summary and Key Messages: The peripheral blood of cancer patients is a pool of cells and/or cell products derived from the primary or metastatic tumor, including circulating tumor cells (CTCs), circulating free (cf) DNA or RNA, and exosomes containing proteins, nucleic acids, and lipids. CTCs are tumor cells that can be isolated from peripheral blood. Free circulating DNA wit...
Source: Digestion - December 14, 2018 Category: Gastroenterology Source Type: research

Irritable Bowel Syndrome-Like Symptoms in Ulcerative Colitis Patients in Clinical Remission: Association with Residual Colonic Inflammation
Ulcerative colitis (UC) patients in clinical remission often experience irritable bowel syndrome (IBS)-like symptoms. The prevalence rate of UC patients meeting the definition of IBS, such as shown by the Rome criteria, is significantly higher in those without ongoing clinical activity as compared to healthy controls. Several studies have investigated residual low-grade inflammation found in colonic mucosa of quiescent UC patients and its association with development of IBS-like symptoms. In these patients, residual colonic inflammation was evaluated using endoscopy and histology findings, as well as fecal calprotectin lev...
Source: Digestion - December 14, 2018 Category: Gastroenterology Source Type: research

Recurrence Patterns and Outcomes of Salvage Surgery in Cases of Non-Curative Endoscopic Submucosal Dissection without Additional Radical Surgery for Early Gastric Cancer
Conclusion: The survival rate after salvage surgery for recurrence after non-curative ESD without additional radical surgery for EGC is quite low, with distant metastasis being the most common recurrence pattern in these cases.Digestion 2019;99:52 –58 (Source: Digestion)
Source: Digestion - December 14, 2018 Category: Gastroenterology Source Type: research