Gastric Cancer with Submucosal Invasion after Successful < b > < i > Helicobacter pylori < /i > < /b > Eradication: A Propensity Score-Matched Analysis of Patients with Annual Patient Endoscopic Survey
Conclusion:H. pylori eradication therapy increased the prevalence of differentiated-type gastric cancer with submucosal invasion despite patients ’ completion of annual endoscopic screening after eradication.Digestion 2019;99:59 –65 (Source: Digestion)
Source: Digestion - December 14, 2018 Category: Gastroenterology Source Type: research

Pilot Study Indicates < b > < i > Helicobacter pylori < /i > < /b > Infection May Induce Small Intestinal Mucosal Injury
Conclusion: There is a possibility thatH. pylori infection induces small intestinal mucosal injury.Digestion 2019;99:66 –71 (Source: Digestion)
Source: Digestion - December 14, 2018 Category: Gastroenterology Source Type: research

Clinical Outcomes of Patients with Small Rectal Neuroendocrine Tumors Treated Using Endoscopic Submucosal Resection with a Ligation Device
Conclusion: ESMR-L is an easy, safe and effective treatment for rectal NETs #x3c;10 mm in diameter, and the prognosis of patients seems to be good, despite a relatively high rate of lymphovascular invasion.Digestion 2019;99:72 –78 (Source: Digestion)
Source: Digestion - December 14, 2018 Category: Gastroenterology Source Type: research

Low Skeletal Muscle Mass before Salvage-Line Chemotherapy Is a Poor Prognostic Factor in Patients with Refractory Metastatic Colorectal Cancer
Conclusion: Low skeletal muscle mass is a negative factor for survival outcomes in mCRC patients treated with salvage-line chemotherapy.Digestion 2019;99:79 –85 (Source: Digestion)
Source: Digestion - December 14, 2018 Category: Gastroenterology Source Type: research

Questionnaire-Based Survey on Management of Ulcerative Colitis-Associated Cancer in East Asian Countries
Conclusions: The current survey elucidated the current management in Asian countries and characteristics of colitis-associated cancer in these countries.Digestion 2019;99:86 –94 (Source: Digestion)
Source: Digestion - December 14, 2018 Category: Gastroenterology Source Type: research

IGICS: JGA Keynote Program. The 10th International Gastrointestinal Consensus Symposium (IGICS). Gastrointestinal Cancer and Gastrointestinal Infection. February 10, 2018: Abstracts
Digestion 2019;99:95 –119 (Source: Digestion)
Source: Digestion - December 14, 2018 Category: Gastroenterology Source Type: research

Effects of Early Initiation of Solid Versus Liquid Diet after Endoscopic Submucosal Dissection on Quality of Life and Postoperative Outcomes: A Prospective Pilot Randomized Controlled Trial
Conclusion: Early initiation of solid foods after ESD is feasible and associated with higher QOL, potentially rendering conventional liquid diets unnecessary, although additional studies are needed (Trial registration number: UMIN000013297).Digestion (Source: Digestion)
Source: Digestion - December 14, 2018 Category: Gastroenterology Source Type: research

Metabolic Alterations in Celiac Disease Occurring after Following a Gluten-Free Diet
Conclusion: In CD patients, following a GFD maybe can contribute to the development of MS and HS. Patients should be informed about this possible risk.Digestion (Source: Digestion)
Source: Digestion - December 14, 2018 Category: Gastroenterology Source Type: research

Shorter Relapse-Free Period after Leukocyte Removal Therapy in Younger than Older Patients with Ulcerative Colitis
Conclusions: The relapse-free period after LRT was examined in patients with UC, and 34.7% of patients achieved clinical remission within a 5-year period. The risk factor for early relapse after LRT was younger age.Digestion (Source: Digestion)
Source: Digestion - December 13, 2018 Category: Gastroenterology Source Type: research

Gastric Focal Neutrophil Infiltration and Wide Duodenal Gastric Foveolar Metaplasia Are Histologic Discriminative Markers for Crohn ’s Disease and Behçet’s Disease
Conclusions: InH. pylori-negative patients, gastric focal neutrophil infiltration and wide duodenal gastric foveolar metaplasia were important for distinguishing CD from BD.Digestion (Source: Digestion)
Source: Digestion - December 13, 2018 Category: Gastroenterology Source Type: research

Nonalcoholic-Fatty-Liver-Disease and Nonalcoholic Steatohepatitis: Successful Development of Pharmacological Treatment Will Depend on Translational Research
Background: Nonalcoholic-fatty-liver-disease/nonalcoholic steatohepatitis (NAFLD/NASH) is expected to become the leading liver disease worldwide. Typical liver-related complications are fibrosis, cirrhosis, and the development of hepatocellular cancer (HCC) with the need for liver transplantation. Up to now there is no approved pharmacotherapy. Indeed, this might be due to the complexity of this disease. While the cheapest therapeutic approach is still a lifestyle change leading to weight loss, the proportion of people achieving sufficient weight reduction without additional support is low. Newly developed drugs are expens...
Source: Digestion - December 7, 2018 Category: Gastroenterology Source Type: research

Efficacy of Clutch Cutter for Standardizing Endoscopic Submucosal Dissection for Early Gastric Cancer: A Propensity Score-Matched Analysis
Conclusion: Better self-completion rates and shorter procedure times were noted for gastric ESD using the CC by nonexperts than for that using IT2, probably due to hemostatic efficacy.Digestion (Source: Digestion)
Source: Digestion - December 6, 2018 Category: Gastroenterology Source Type: research

Effect of Continued Administration of Low-dose Aspirin for Intraoperative Bleeding Control in Gastric Endoscopic Submucosal Dissection
Conclusion: The study suggests that gastric ESD can be safely accomplished without cessation of LDA.Digestion (Source: Digestion)
Source: Digestion - December 4, 2018 Category: Gastroenterology Source Type: research

Gankyrin Contributes to Tumorigenesis and Chemoresistance in Sporadic Colorectal Cancer
Conclusion: Gankyrin in epithelial cell contributes to the development of sporadic CRC and the expression could serve as a biomarker to predict therapeutic response in patients with metastatic CRC.Digestion (Source: Digestion)
Source: Digestion - December 4, 2018 Category: Gastroenterology Source Type: research

Utility of Endoscopic Submucosal Dissection in the Remnant Stomach and Clinical Outcomes for Different Reconstruction Methods
Conclusions: Although technically demanding, ESD for early gastric tumor in the remnant stomach was a safe and effective therapeutic method. However, because the curative resection rate was lower for the more frequent lesions occurring at the anastomosis site after Billroth II reconstruction, early detection of remnant stomach tumor is desirable after Billroth II reconstruction following DG.Digestion (Source: Digestion)
Source: Digestion - November 28, 2018 Category: Gastroenterology Source Type: research