Bleeding following Endoscopic Submucosal Dissection for Early Gastric Cancer in Surgically Altered Stomach
Conclusion: In this nationwide study, we found that the bleeding risk of surgically altered stomach following ESD for EGC did not significantly differ from that of whole stomach. The risk factors for ESD in patients with surgically altered stomach were ischemic heart disease and P2Y12 receptor antagonist.Digestion (Source: Digestion)
Source: Digestion - October 4, 2022 Category: Gastroenterology Source Type: research
Recent Topics in the Pathophysiology and Medical Management of Inflammatory Bowel Disease
Digestion (Source: Digestion)
Source: Digestion - September 8, 2022 Category: Gastroenterology Source Type: research
Analysis of Barrett ’s Esophagus and Its Risk Factors: A Cross-Sectional Study of 10,122 Subjects at a Japanese Health Examination Center
Conclusions:H. pylori eradication, bile reflux, PPI use, and NSAID use were risk factors for BE along with hiatal hernia, male sex, and older age.Digestion (Source: Digestion)
Source: Digestion - September 8, 2022 Category: Gastroenterology Source Type: research
Alteration of the Gut Microbiome in Inflammatory Bowel Disease
Background: Alteration of the gut microbial structure and function (dysbiosis) is associated with the pathogenesis of various disorders including inflammatory bowel disease (IBD).Summary: Under normal conditions, β-oxidation of butyrate consumes oxygen in colonocytes and maintains the anaerobic environment in the lumen. Depletion of butyrate-producing bacteria results in anaerobic glycolysis in colonocytes and increases oxygen diffusion into the lumen, leading to a luminal facultative anaerobe expansion. Dy sbiosis in IBD is characterized by the reduced abundance of the phylum Firmicutes (e.g.,Faecalibacterium,Roseburia, ...
Source: Digestion - July 28, 2022 Category: Gastroenterology Source Type: research
Endoscopic Submucosal Dissection for Early Gastric Cancer in Patients Aged 85 Years Old or Older Is Associated with a Good Prognosis Compared to Conservative Treatment without Any Invasive Procedure
Conclusion: ESD was associated with improved OS in patients with clinical T1N0 EGC aged ≥85 years compared with the absence of treatment. Furthermore, CCI and PNI were helpful for patient selection.Digestion (Source: Digestion)
Source: Digestion - July 21, 2022 Category: Gastroenterology Source Type: research
Making Hematochezia of Unknown Origin Known: A Retrospective Analysis
Conclusion: In patients with hematochezia of unknown origin, risk factors for rebleeding indicated in this study, especially the presence of diverticula and male gender, should be given particular attention by physicians.Digestion (Source: Digestion)
Source: Digestion - July 13, 2022 Category: Gastroenterology Source Type: research
Predictive Value of Liver Stiffness Measurement by Magnetic Resonance Elastography for Complications after Liver Resection: A Systematic Review and Meta-Analysis
Conclusions: In conclusion, liver stiffness measured by MRE was a significant predictor of postoperative outcomes in patients undergoing liver resection. Future studies could focus on setting a prognostic model integrated with LSM by MRE in distinguishing patients at high risk of posthepatectomy complications.Digestion (Source: Digestion)
Source: Digestion - July 1, 2022 Category: Gastroenterology Source Type: research
Efficacy of Early Video Capsule Endoscopy for Acute Overt Lower Gastrointestinal Bleeding with Colonic Diverticulosis: A Prospective Observational Study
Conclusion: Early CE detected a suspected small bowel bleeding source in 12% of acute-onset presumptive CDB patients but did not significantly improve major clinical outcomes. Therefore, routine CE is unnecessary for presumptive CDB patients after colonoscopy (UMIN000026676).Digestion (Source: Digestion)
Source: Digestion - June 30, 2022 Category: Gastroenterology Source Type: research
Frame-by-Frame Analysis of a Commercially Available Artificial Intelligence Polyp Detection System in Full-Length Colonoscopies
Conclusions: The CADe system works reliable but generates many FPs as a side effect. Since most FPs are very short, withholding short-term CADe activations could substantially reduce the number of FPs without impact on other performance metrics. Clinical practice would benefit from the implementation of customizable CADe thresholds.Digestion (Source: Digestion)
Source: Digestion - June 29, 2022 Category: Gastroenterology Source Type: research
Preoperative Risk Factors and Prognostic Impact of Postoperative Complications Associated with Total Gastrectomy
Conclusion: Patients with postoperative complications are prone to recurrence and poor prognosis. For patients with high-risk GC with poor ASA-PS and high NLR, more thorough perioperative management is essential.Digestion (Source: Digestion)
Source: Digestion - June 20, 2022 Category: Gastroenterology Source Type: research
Clinical and Histopathological Features of the Differentiated Type of Early Gastric Cancer with an Unclear Lateral Demarcation
Conclusions: The nonneoplastic superficial epithelium and a low p53 score were associated with difficulties in determining the lateral demarcation in early gastric cancers on M-NBI.Digestion (Source: Digestion)
Source: Digestion - June 16, 2022 Category: Gastroenterology Source Type: research
Risk Factors for Nephrotoxicity due to Tacrolimus Therapy for Ulcerative Colitis
Conclusion: We revealed the risk factors for tacrolimus-induced nephrotoxicity. Renal impairment occurrence adversely affected the tacrolimus treatment outcome; therefore, it is important to carefully administer tacrolimus to prevent renal impairment.Digestion (Source: Digestion)
Source: Digestion - June 15, 2022 Category: Gastroenterology Source Type: research
Therapeutic Drug Monitoring of Golimumab for the Prediction of Long-Term Clinical Remission in Patients with Ulcerative Colitis
Conclusion: Our results demonstrate the value of early serum GLM TLs in predicting the long-term outcomes of GLM for patients with UC.Digestion (Source: Digestion)
Source: Digestion - June 13, 2022 Category: Gastroenterology Source Type: research
Comparison of Endoscopic Ultrasonography and Conventional Endoscopy for Prediction of Tumor Depth in Superficial Nonampullary Duodenal Epithelial Tumors
Conclusion: EUS may not be necessary, and CE may be sufficient for determining the optimal therapeutic strategy for SNADETs.Digestion (Source: Digestion)
Source: Digestion - June 1, 2022 Category: Gastroenterology Source Type: research
Gastrointestinal Quality of Life in Gastroesophageal Reflux Disease: A Systematic Review
Conclusions: Severe GERD causes substantial reductions in the patient ’s QOL. The level of GIQLI can carry between different studied GERD cohorts from different departments and countries. GIQLI can be used as an established tool to assess the patient’s condition in various dimensions.Digestion (Source: Digestion)
Source: Digestion - May 23, 2022 Category: Gastroenterology Source Type: research
