Metabolic Endoscopy: Development and Perspectives

This article will therefore highlight procedures with data on type 2 d iabetes mellitus (T2DM) as the most prominent component of the metabolic syndrome.Summary: Most procedures showed beneficial effects in terms of weight reduction. For gastric procedures, there were no systematic studies primarily addressing parameters of glucose metabolism or diabetes outcomes. Metabolic benefit, if there is any, is most likely a by-product of weight loss. By contrast, duodenal-jejunal bypass sleeve (DJBS) is conceptually an antidiabetic procedure. Although adverse events are frequent, recent data points to a positive benefit-risk ratio.Key Messages: ME has the potential to constitute a growing field in the treatment of obesity and associated T2DM. While data published on glycaemic parameters in restrictive approaches is not sufficient, there is strong evidence that malabsorptive DJBS has an antidiabetic “plus” effect. Further studies are necessary to define the role of ME within a lifelong concept of treating obesity and T2DM.Digestion

Source: Digestion - February 7, 2019 Category: Gastroenterology Source Type: research