AKT from dental epithelium to papilla promotes odontoblast differentiation
Differentiation. 2023 Oct 21;134:52-60. doi: 10.1016/j.diff.2023.10.002. Online ahead of print.ABSTRACTEpithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear. Using miniature pigs as a model, we analyzed the expression profiles of the DE and DP during odontoblast differentiation using high-throughput RNA sequencing. The phosphatidylinositol-3-kinase (PI3K)/AKT pathway is one of th...
Source: Differentiation - October 28, 2023 Category: Research Authors: Jiangyi Wang Xiaoyu Lin Zongshan Shen Guoqing Li Lei Hu Qiong Li Yang Li Jinsong Wang Chunmei Zhang Songlin Wang Xiaoshan Wu Source Type: research
AKT from dental epithelium to papilla promotes odontoblast differentiation
Differentiation. 2023 Oct 21;134:52-60. doi: 10.1016/j.diff.2023.10.002. Online ahead of print.ABSTRACTEpithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear. Using miniature pigs as a model, we analyzed the expression profiles of the DE and DP during odontoblast differentiation using high-throughput RNA sequencing. The phosphatidylinositol-3-kinase (PI3K)/AKT pathway is one of th...
Source: Differentiation - October 28, 2023 Category: Research Authors: Jiangyi Wang Xiaoyu Lin Zongshan Shen Guoqing Li Lei Hu Qiong Li Yang Li Jinsong Wang Chunmei Zhang Songlin Wang Xiaoshan Wu Source Type: research
AKT from dental epithelium to papilla promotes odontoblast differentiation
Differentiation. 2023 Oct 21;134:52-60. doi: 10.1016/j.diff.2023.10.002. Online ahead of print.ABSTRACTEpithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear. Using miniature pigs as a model, we analyzed the expression profiles of the DE and DP during odontoblast differentiation using high-throughput RNA sequencing. The phosphatidylinositol-3-kinase (PI3K)/AKT pathway is one of th...
Source: Differentiation - October 28, 2023 Category: Research Authors: Jiangyi Wang Xiaoyu Lin Zongshan Shen Guoqing Li Lei Hu Qiong Li Yang Li Jinsong Wang Chunmei Zhang Songlin Wang Xiaoshan Wu Source Type: research
AKT from dental epithelium to papilla promotes odontoblast differentiation
Differentiation. 2023 Oct 21;134:52-60. doi: 10.1016/j.diff.2023.10.002. Online ahead of print.ABSTRACTEpithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear. Using miniature pigs as a model, we analyzed the expression profiles of the DE and DP during odontoblast differentiation using high-throughput RNA sequencing. The phosphatidylinositol-3-kinase (PI3K)/AKT pathway is one of th...
Source: Differentiation - October 28, 2023 Category: Research Authors: Jiangyi Wang Xiaoyu Lin Zongshan Shen Guoqing Li Lei Hu Qiong Li Yang Li Jinsong Wang Chunmei Zhang Songlin Wang Xiaoshan Wu Source Type: research
AKT from dental epithelium to papilla promotes odontoblast differentiation
Differentiation. 2023 Oct 21;134:52-60. doi: 10.1016/j.diff.2023.10.002. Online ahead of print.ABSTRACTEpithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear. Using miniature pigs as a model, we analyzed the expression profiles of the DE and DP during odontoblast differentiation using high-throughput RNA sequencing. The phosphatidylinositol-3-kinase (PI3K)/AKT pathway is one of th...
Source: Differentiation - October 28, 2023 Category: Research Authors: Jiangyi Wang Xiaoyu Lin Zongshan Shen Guoqing Li Lei Hu Qiong Li Yang Li Jinsong Wang Chunmei Zhang Songlin Wang Xiaoshan Wu Source Type: research
AKT from dental epithelium to papilla promotes odontoblast differentiation
Differentiation. 2023 Oct 21;134:52-60. doi: 10.1016/j.diff.2023.10.002. Online ahead of print.ABSTRACTEpithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear. Using miniature pigs as a model, we analyzed the expression profiles of the DE and DP during odontoblast differentiation using high-throughput RNA sequencing. The phosphatidylinositol-3-kinase (PI3K)/AKT pathway is one of th...
Source: Differentiation - October 28, 2023 Category: Research Authors: Jiangyi Wang Xiaoyu Lin Zongshan Shen Guoqing Li Lei Hu Qiong Li Yang Li Jinsong Wang Chunmei Zhang Songlin Wang Xiaoshan Wu Source Type: research
AKT from dental epithelium to papilla promotes odontoblast differentiation
Differentiation. 2023 Oct 21;134:52-60. doi: 10.1016/j.diff.2023.10.002. Online ahead of print.ABSTRACTEpithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear. Using miniature pigs as a model, we analyzed the expression profiles of the DE and DP during odontoblast differentiation using high-throughput RNA sequencing. The phosphatidylinositol-3-kinase (PI3K)/AKT pathway is one of th...
Source: Differentiation - October 28, 2023 Category: Research Authors: Jiangyi Wang Xiaoyu Lin Zongshan Shen Guoqing Li Lei Hu Qiong Li Yang Li Jinsong Wang Chunmei Zhang Songlin Wang Xiaoshan Wu Source Type: research
AKT from dental epithelium to papilla promotes odontoblast differentiation
Differentiation. 2023 Oct 21;134:52-60. doi: 10.1016/j.diff.2023.10.002. Online ahead of print.ABSTRACTEpithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear. Using miniature pigs as a model, we analyzed the expression profiles of the DE and DP during odontoblast differentiation using high-throughput RNA sequencing. The phosphatidylinositol-3-kinase (PI3K)/AKT pathway is one of th...
Source: Differentiation - October 28, 2023 Category: Research Authors: Jiangyi Wang Xiaoyu Lin Zongshan Shen Guoqing Li Lei Hu Qiong Li Yang Li Jinsong Wang Chunmei Zhang Songlin Wang Xiaoshan Wu Source Type: research
AKT from dental epithelium to papilla promotes odontoblast differentiation
Differentiation. 2023 Oct 21;134:52-60. doi: 10.1016/j.diff.2023.10.002. Online ahead of print.ABSTRACTEpithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear. Using miniature pigs as a model, we analyzed the expression profiles of the DE and DP during odontoblast differentiation using high-throughput RNA sequencing. The phosphatidylinositol-3-kinase (PI3K)/AKT pathway is one of th...
Source: Differentiation - October 28, 2023 Category: Research Authors: Jiangyi Wang Xiaoyu Lin Zongshan Shen Guoqing Li Lei Hu Qiong Li Yang Li Jinsong Wang Chunmei Zhang Songlin Wang Xiaoshan Wu Source Type: research
AKT from dental epithelium to papilla promotes odontoblast differentiation
Differentiation. 2023 Oct 21;134:52-60. doi: 10.1016/j.diff.2023.10.002. Online ahead of print.ABSTRACTEpithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear. Using miniature pigs as a model, we analyzed the expression profiles of the DE and DP during odontoblast differentiation using high-throughput RNA sequencing. The phosphatidylinositol-3-kinase (PI3K)/AKT pathway is one of th...
Source: Differentiation - October 28, 2023 Category: Research Authors: Jiangyi Wang Xiaoyu Lin Zongshan Shen Guoqing Li Lei Hu Qiong Li Yang Li Jinsong Wang Chunmei Zhang Songlin Wang Xiaoshan Wu Source Type: research
AKT from dental epithelium to papilla promotes odontoblast differentiation
Differentiation. 2023 Oct 21;134:52-60. doi: 10.1016/j.diff.2023.10.002. Online ahead of print.ABSTRACTEpithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear. Using miniature pigs as a model, we analyzed the expression profiles of the DE and DP during odontoblast differentiation using high-throughput RNA sequencing. The phosphatidylinositol-3-kinase (PI3K)/AKT pathway is one of th...
Source: Differentiation - October 28, 2023 Category: Research Authors: Jiangyi Wang Xiaoyu Lin Zongshan Shen Guoqing Li Lei Hu Qiong Li Yang Li Jinsong Wang Chunmei Zhang Songlin Wang Xiaoshan Wu Source Type: research
AKT from dental epithelium to papilla promotes odontoblast differentiation
Differentiation. 2023 Oct 21;134:52-60. doi: 10.1016/j.diff.2023.10.002. Online ahead of print.ABSTRACTEpithelial-mesenchymal interactions occur during tooth development. The dental epithelium (DE) is regarded as the signal center that regulates tooth morphology. However, the mechanism by which DE regulates the differentiation of mesenchyme-derived dental papilla (DP) into odontoblasts remains unclear. Using miniature pigs as a model, we analyzed the expression profiles of the DE and DP during odontoblast differentiation using high-throughput RNA sequencing. The phosphatidylinositol-3-kinase (PI3K)/AKT pathway is one of th...
Source: Differentiation - October 28, 2023 Category: Research Authors: Jiangyi Wang Xiaoyu Lin Zongshan Shen Guoqing Li Lei Hu Qiong Li Yang Li Jinsong Wang Chunmei Zhang Songlin Wang Xiaoshan Wu Source Type: research
Fibroblast growth factor 2
Differentiation. 2023 Oct 12:S0301-4681(23)00072-5. doi: 10.1016/j.diff.2023.10.001. Online ahead of print.ABSTRACTFibroblast Growth Factor 2 (FGF2), also known as basic fibroblast growth factor, is a potent stimulator of growth and differentiation in multiple tissues. Its discovery traces back over 50 years ago when it was first isolated from bovine pituitary extracts due to its ability to stimulate fibroblast proliferation. Subsequent studies investigating the genomic structure of FGF2 identified multiple protein isoforms, categorized as the low molecular weight and high molecular weight FGF2. These isoforms arise from a...
Source: Differentiation - October 20, 2023 Category: Research Authors: Audrey Nickle Sebastian Ko Amy E Merrill Source Type: research
Fibroblast growth factor 2
Differentiation. 2023 Oct 12:S0301-4681(23)00072-5. doi: 10.1016/j.diff.2023.10.001. Online ahead of print.ABSTRACTFibroblast Growth Factor 2 (FGF2), also known as basic fibroblast growth factor, is a potent stimulator of growth and differentiation in multiple tissues. Its discovery traces back over 50 years ago when it was first isolated from bovine pituitary extracts due to its ability to stimulate fibroblast proliferation. Subsequent studies investigating the genomic structure of FGF2 identified multiple protein isoforms, categorized as the low molecular weight and high molecular weight FGF2. These isoforms arise from a...
Source: Differentiation - October 20, 2023 Category: Research Authors: Audrey Nickle Sebastian Ko Amy E Merrill Source Type: research
Fibroblast growth factor 2
Differentiation. 2023 Oct 12:S0301-4681(23)00072-5. doi: 10.1016/j.diff.2023.10.001. Online ahead of print.ABSTRACTFibroblast Growth Factor 2 (FGF2), also known as basic fibroblast growth factor, is a potent stimulator of growth and differentiation in multiple tissues. Its discovery traces back over 50 years ago when it was first isolated from bovine pituitary extracts due to its ability to stimulate fibroblast proliferation. Subsequent studies investigating the genomic structure of FGF2 identified multiple protein isoforms, categorized as the low molecular weight and high molecular weight FGF2. These isoforms arise from a...
Source: Differentiation - October 20, 2023 Category: Research Authors: Audrey Nickle Sebastian Ko Amy E Merrill Source Type: research
