Oxidative-stress induced Bmp2-Smad1/5/8 signaling dependent differentiation of early cardiomyocytes from embryonic and adult epicardial cells
Differentiation. 2024 Mar-Apr;136:100756. doi: 10.1016/j.diff.2024.100756. Epub 2024 Mar 2.ABSTRACTHeart failure has become a major life-threatening cause affecting millions globally, characterized by the permanent loss of adult functional cardiomyocytes leading to fibrosis which ultimately deprives the heart of its functional efficacy. Here we investigated the reparative property of embryonic and adult epicardial cells towards cardiomyocyte differentiation under oxidative stress-induced conditions along with the identification of a possible molecular signaling pathway. Isolated epicardial cells from embryonic chick hearts...
Source: Differentiation - March 12, 2024 Category: Research Authors: Madhurima Ghosh Riffat Khanam Arunima Sengupta Santanu Chakraborty Source Type: research
Oxidative-stress induced Bmp2-Smad1/5/8 signaling dependent differentiation of early cardiomyocytes from embryonic and adult epicardial cells
Differentiation. 2024 Mar-Apr;136:100756. doi: 10.1016/j.diff.2024.100756. Epub 2024 Mar 2.ABSTRACTHeart failure has become a major life-threatening cause affecting millions globally, characterized by the permanent loss of adult functional cardiomyocytes leading to fibrosis which ultimately deprives the heart of its functional efficacy. Here we investigated the reparative property of embryonic and adult epicardial cells towards cardiomyocyte differentiation under oxidative stress-induced conditions along with the identification of a possible molecular signaling pathway. Isolated epicardial cells from embryonic chick hearts...
Source: Differentiation - March 12, 2024 Category: Research Authors: Madhurima Ghosh Riffat Khanam Arunima Sengupta Santanu Chakraborty Source Type: research
Oxidative-stress induced Bmp2-Smad1/5/8 signaling dependent differentiation of early cardiomyocytes from embryonic and adult epicardial cells
Differentiation. 2024 Mar-Apr;136:100756. doi: 10.1016/j.diff.2024.100756. Epub 2024 Mar 2.ABSTRACTHeart failure has become a major life-threatening cause affecting millions globally, characterized by the permanent loss of adult functional cardiomyocytes leading to fibrosis which ultimately deprives the heart of its functional efficacy. Here we investigated the reparative property of embryonic and adult epicardial cells towards cardiomyocyte differentiation under oxidative stress-induced conditions along with the identification of a possible molecular signaling pathway. Isolated epicardial cells from embryonic chick hearts...
Source: Differentiation - March 12, 2024 Category: Research Authors: Madhurima Ghosh Riffat Khanam Arunima Sengupta Santanu Chakraborty Source Type: research
Oxidative-stress induced Bmp2-Smad1/5/8 signaling dependent differentiation of early cardiomyocytes from embryonic and adult epicardial cells
Differentiation. 2024 Mar-Apr;136:100756. doi: 10.1016/j.diff.2024.100756. Epub 2024 Mar 2.ABSTRACTHeart failure has become a major life-threatening cause affecting millions globally, characterized by the permanent loss of adult functional cardiomyocytes leading to fibrosis which ultimately deprives the heart of its functional efficacy. Here we investigated the reparative property of embryonic and adult epicardial cells towards cardiomyocyte differentiation under oxidative stress-induced conditions along with the identification of a possible molecular signaling pathway. Isolated epicardial cells from embryonic chick hearts...
Source: Differentiation - March 12, 2024 Category: Research Authors: Madhurima Ghosh Riffat Khanam Arunima Sengupta Santanu Chakraborty Source Type: research
Oxidative-stress induced Bmp2-Smad1/5/8 signaling dependent differentiation of early cardiomyocytes from embryonic and adult epicardial cells
Differentiation. 2024 Mar 2;136:100756. doi: 10.1016/j.diff.2024.100756. Online ahead of print.ABSTRACTHeart failure has become a major life-threatening cause affecting millions globally, characterized by the permanent loss of adult functional cardiomyocytes leading to fibrosis which ultimately deprives the heart of its functional efficacy. Here we investigated the reparative property of embryonic and adult epicardial cells towards cardiomyocyte differentiation under oxidative stress-induced conditions along with the identification of a possible molecular signaling pathway. Isolated epicardial cells from embryonic chick he...
Source: Differentiation - March 12, 2024 Category: Research Authors: Madhurima Ghosh Riffat Khanam Arunima Sengupta Santanu Chakraborty Source Type: research
Oxidative-stress induced Bmp2-Smad1/5/8 signaling dependent differentiation of early cardiomyocytes from embryonic and adult epicardial cells
Differentiation. 2024 Mar 2;136:100756. doi: 10.1016/j.diff.2024.100756. Online ahead of print.ABSTRACTHeart failure has become a major life-threatening cause affecting millions globally, characterized by the permanent loss of adult functional cardiomyocytes leading to fibrosis which ultimately deprives the heart of its functional efficacy. Here we investigated the reparative property of embryonic and adult epicardial cells towards cardiomyocyte differentiation under oxidative stress-induced conditions along with the identification of a possible molecular signaling pathway. Isolated epicardial cells from embryonic chick he...
Source: Differentiation - March 12, 2024 Category: Research Authors: Madhurima Ghosh Riffat Khanam Arunima Sengupta Santanu Chakraborty Source Type: research
Oxidative-stress induced Bmp2-Smad1/5/8 signaling dependent differentiation of early cardiomyocytes from embryonic and adult epicardial cells
Differentiation. 2024 Mar 2;136:100756. doi: 10.1016/j.diff.2024.100756. Online ahead of print.ABSTRACTHeart failure has become a major life-threatening cause affecting millions globally, characterized by the permanent loss of adult functional cardiomyocytes leading to fibrosis which ultimately deprives the heart of its functional efficacy. Here we investigated the reparative property of embryonic and adult epicardial cells towards cardiomyocyte differentiation under oxidative stress-induced conditions along with the identification of a possible molecular signaling pathway. Isolated epicardial cells from embryonic chick he...
Source: Differentiation - March 12, 2024 Category: Research Authors: Madhurima Ghosh Riffat Khanam Arunima Sengupta Santanu Chakraborty Source Type: research
Oxidative-stress induced Bmp2-Smad1/5/8 signaling dependent differentiation of early cardiomyocytes from embryonic and adult epicardial cells
Differentiation. 2024 Mar 2;136:100756. doi: 10.1016/j.diff.2024.100756. Online ahead of print.ABSTRACTHeart failure has become a major life-threatening cause affecting millions globally, characterized by the permanent loss of adult functional cardiomyocytes leading to fibrosis which ultimately deprives the heart of its functional efficacy. Here we investigated the reparative property of embryonic and adult epicardial cells towards cardiomyocyte differentiation under oxidative stress-induced conditions along with the identification of a possible molecular signaling pathway. Isolated epicardial cells from embryonic chick he...
Source: Differentiation - March 12, 2024 Category: Research Authors: Madhurima Ghosh Riffat Khanam Arunima Sengupta Santanu Chakraborty Source Type: research
Oxidative-stress induced Bmp2-Smad1/5/8 signaling dependent differentiation of early cardiomyocytes from embryonic and adult epicardial cells
Differentiation. 2024 Mar 2;136:100756. doi: 10.1016/j.diff.2024.100756. Online ahead of print.ABSTRACTHeart failure has become a major life-threatening cause affecting millions globally, characterized by the permanent loss of adult functional cardiomyocytes leading to fibrosis which ultimately deprives the heart of its functional efficacy. Here we investigated the reparative property of embryonic and adult epicardial cells towards cardiomyocyte differentiation under oxidative stress-induced conditions along with the identification of a possible molecular signaling pathway. Isolated epicardial cells from embryonic chick he...
Source: Differentiation - March 12, 2024 Category: Research Authors: Madhurima Ghosh Riffat Khanam Arunima Sengupta Santanu Chakraborty Source Type: research
Type 1 collagen: Synthesis, structure and key functions in bone mineralization
Differentiation. 2024 Feb 28;136:100757. doi: 10.1016/j.diff.2024.100757. Online ahead of print.ABSTRACTCollagen is a highly abundant protein in the extracellular matrix of humans and mammals, and it plays a critical role in maintaining the body's structural integrity. Type I collagen is the most prevalent collagen type and is essential for the structural integrity of various tissues. It is present in nearly all connective tissues and is the main constituent of the interstitial matrix. Mutations that affect collagen fiber formation, structure, and function can result in various bone pathologies, underscoring the significan...
Source: Differentiation - March 4, 2024 Category: Research Authors: Vimalraj Selvaraj Saravanan Sekaran Anuradha Dhanasekaran Sudha Warrier Source Type: research
Type 1 collagen: Synthesis, structure and key functions in bone mineralization
Differentiation. 2024 Feb 28;136:100757. doi: 10.1016/j.diff.2024.100757. Online ahead of print.ABSTRACTCollagen is a highly abundant protein in the extracellular matrix of humans and mammals, and it plays a critical role in maintaining the body's structural integrity. Type I collagen is the most prevalent collagen type and is essential for the structural integrity of various tissues. It is present in nearly all connective tissues and is the main constituent of the interstitial matrix. Mutations that affect collagen fiber formation, structure, and function can result in various bone pathologies, underscoring the significan...
Source: Differentiation - March 4, 2024 Category: Research Authors: Vimalraj Selvaraj Saravanan Sekaran Anuradha Dhanasekaran Sudha Warrier Source Type: research
Type 1 collagen: Synthesis, structure and key functions in bone mineralization
Differentiation. 2024 Feb 28;136:100757. doi: 10.1016/j.diff.2024.100757. Online ahead of print.ABSTRACTCollagen is a highly abundant protein in the extracellular matrix of humans and mammals, and it plays a critical role in maintaining the body's structural integrity. Type I collagen is the most prevalent collagen type and is essential for the structural integrity of various tissues. It is present in nearly all connective tissues and is the main constituent of the interstitial matrix. Mutations that affect collagen fiber formation, structure, and function can result in various bone pathologies, underscoring the significan...
Source: Differentiation - March 4, 2024 Category: Research Authors: Vimalraj Selvaraj Saravanan Sekaran Anuradha Dhanasekaran Sudha Warrier Source Type: research
Type 1 collagen: Synthesis, structure and key functions in bone mineralization
Differentiation. 2024 Feb 28;136:100757. doi: 10.1016/j.diff.2024.100757. Online ahead of print.ABSTRACTCollagen is a highly abundant protein in the extracellular matrix of humans and mammals, and it plays a critical role in maintaining the body's structural integrity. Type I collagen is the most prevalent collagen type and is essential for the structural integrity of various tissues. It is present in nearly all connective tissues and is the main constituent of the interstitial matrix. Mutations that affect collagen fiber formation, structure, and function can result in various bone pathologies, underscoring the significan...
Source: Differentiation - March 4, 2024 Category: Research Authors: Vimalraj Selvaraj Saravanan Sekaran Anuradha Dhanasekaran Sudha Warrier Source Type: research
Type 1 collagen: Synthesis, structure and key functions in bone mineralization
Differentiation. 2024 Feb 28;136:100757. doi: 10.1016/j.diff.2024.100757. Online ahead of print.ABSTRACTCollagen is a highly abundant protein in the extracellular matrix of humans and mammals, and it plays a critical role in maintaining the body's structural integrity. Type I collagen is the most prevalent collagen type and is essential for the structural integrity of various tissues. It is present in nearly all connective tissues and is the main constituent of the interstitial matrix. Mutations that affect collagen fiber formation, structure, and function can result in various bone pathologies, underscoring the significan...
Source: Differentiation - March 4, 2024 Category: Research Authors: Vimalraj Selvaraj Saravanan Sekaran Anuradha Dhanasekaran Sudha Warrier Source Type: research
Type 1 collagen: Synthesis, structure and key functions in bone mineralization
Differentiation. 2024 Feb 28;136:100757. doi: 10.1016/j.diff.2024.100757. Online ahead of print.ABSTRACTCollagen is a highly abundant protein in the extracellular matrix of humans and mammals, and it plays a critical role in maintaining the body's structural integrity. Type I collagen is the most prevalent collagen type and is essential for the structural integrity of various tissues. It is present in nearly all connective tissues and is the main constituent of the interstitial matrix. Mutations that affect collagen fiber formation, structure, and function can result in various bone pathologies, underscoring the significan...
Source: Differentiation - March 4, 2024 Category: Research Authors: Vimalraj Selvaraj Saravanan Sekaran Anuradha Dhanasekaran Sudha Warrier Source Type: research
