Spheroid formation and luteinization of granulosa cells of felids in a long-term 3D culture
This study confirms that GCs from felids can be luteinized in a 3D spheroid system which can be a basis for further studies on luteal cell function of felids. Additionally, we could show that the domestic cat can serve as a model species for establishing cell culture methods which can be transferred to other felids.PMID:37079952 | DOI:10.1016/j.diff.2023.03.002 (Source: Differentiation)
Source: Differentiation - April 20, 2023 Category: Research Authors: Micha ł M Hryciuk Filip Schr öter Luise Hennicke Beate C Braun Source Type: research

Spheroid formation and luteinization of granulosa cells of felids in a long-term 3D culture
This study confirms that GCs from felids can be luteinized in a 3D spheroid system which can be a basis for further studies on luteal cell function of felids. Additionally, we could show that the domestic cat can serve as a model species for establishing cell culture methods which can be transferred to other felids.PMID:37079952 | DOI:10.1016/j.diff.2023.03.002 (Source: Differentiation)
Source: Differentiation - April 20, 2023 Category: Research Authors: Micha ł M Hryciuk Filip Schr öter Luise Hennicke Beate C Braun Source Type: research

Spheroid formation and luteinization of granulosa cells of felids in a long-term 3D culture
This study confirms that GCs from felids can be luteinized in a 3D spheroid system which can be a basis for further studies on luteal cell function of felids. Additionally, we could show that the domestic cat can serve as a model species for establishing cell culture methods which can be transferred to other felids.PMID:37079952 | DOI:10.1016/j.diff.2023.03.002 (Source: Differentiation)
Source: Differentiation - April 20, 2023 Category: Research Authors: Micha ł M Hryciuk Filip Schr öter Luise Hennicke Beate C Braun Source Type: research

Spheroid formation and luteinization of granulosa cells of felids in a long-term 3D culture
This study confirms that GCs from felids can be luteinized in a 3D spheroid system which can be a basis for further studies on luteal cell function of felids. Additionally, we could show that the domestic cat can serve as a model species for establishing cell culture methods which can be transferred to other felids.PMID:37079952 | DOI:10.1016/j.diff.2023.03.002 (Source: Differentiation)
Source: Differentiation - April 20, 2023 Category: Research Authors: Micha ł M Hryciuk Filip Schr öter Luise Hennicke Beate C Braun Source Type: research

Epigenetic regulation in the commitment of progenitor cells during retinal development and regeneration
Differentiation. 2023 Apr 12:S0301-4681(23)00023-3. doi: 10.1016/j.diff.2023.04.002. Online ahead of print.ABSTRACTRetinal development is initiated by multipotent retinal progenitor cells, which undergo several rounds of cell divisions and subsequently terminal differentiation. Retinal regeneration is usually considered as the recapitulation of retinal development, which share common mechanisms underlying the cell cycle re-entry of adult retinal stem cells and the differentiation of retinal neurons. However, how proliferative retinal progenitor cells perform a precise transition to postmitotic retinal cell types during the...
Source: Differentiation - April 17, 2023 Category: Research Authors: Wenjie Yin Xiying Mao Miao Xu Mingkang Chen Mengting Xue Na Su Songtao Yuan Qinghuai Liu Source Type: research

Epigenetic regulation in the commitment of progenitor cells during retinal development and regeneration
Differentiation. 2023 Apr 12:S0301-4681(23)00023-3. doi: 10.1016/j.diff.2023.04.002. Online ahead of print.ABSTRACTRetinal development is initiated by multipotent retinal progenitor cells, which undergo several rounds of cell divisions and subsequently terminal differentiation. Retinal regeneration is usually considered as the recapitulation of retinal development, which share common mechanisms underlying the cell cycle re-entry of adult retinal stem cells and the differentiation of retinal neurons. However, how proliferative retinal progenitor cells perform a precise transition to postmitotic retinal cell types during the...
Source: Differentiation - April 17, 2023 Category: Research Authors: Wenjie Yin Xiying Mao Miao Xu Mingkang Chen Mengting Xue Na Su Songtao Yuan Qinghuai Liu Source Type: research

Epigenetic regulation in the commitment of progenitor cells during retinal development and regeneration
Differentiation. 2023 Apr 12:S0301-4681(23)00023-3. doi: 10.1016/j.diff.2023.04.002. Online ahead of print.ABSTRACTRetinal development is initiated by multipotent retinal progenitor cells, which undergo several rounds of cell divisions and subsequently terminal differentiation. Retinal regeneration is usually considered as the recapitulation of retinal development, which share common mechanisms underlying the cell cycle re-entry of adult retinal stem cells and the differentiation of retinal neurons. However, how proliferative retinal progenitor cells perform a precise transition to postmitotic retinal cell types during the...
Source: Differentiation - April 17, 2023 Category: Research Authors: Wenjie Yin Xiying Mao Miao Xu Mingkang Chen Mengting Xue Na Su Songtao Yuan Qinghuai Liu Source Type: research

Epigenetic regulation in the commitment of progenitor cells during retinal development and regeneration
Differentiation. 2023 Apr 12:S0301-4681(23)00023-3. doi: 10.1016/j.diff.2023.04.002. Online ahead of print.ABSTRACTRetinal development is initiated by multipotent retinal progenitor cells, which undergo several rounds of cell divisions and subsequently terminal differentiation. Retinal regeneration is usually considered as the recapitulation of retinal development, which share common mechanisms underlying the cell cycle re-entry of adult retinal stem cells and the differentiation of retinal neurons. However, how proliferative retinal progenitor cells perform a precise transition to postmitotic retinal cell types during the...
Source: Differentiation - April 17, 2023 Category: Research Authors: Wenjie Yin Xiying Mao Miao Xu Mingkang Chen Mengting Xue Na Su Songtao Yuan Qinghuai Liu Source Type: research

Epigenetic regulation in the commitment of progenitor cells during retinal development and regeneration
Differentiation. 2023 Apr 12:S0301-4681(23)00023-3. doi: 10.1016/j.diff.2023.04.002. Online ahead of print.ABSTRACTRetinal development is initiated by multipotent retinal progenitor cells, which undergo several rounds of cell divisions and subsequently terminal differentiation. Retinal regeneration is usually considered as the recapitulation of retinal development, which share common mechanisms underlying the cell cycle re-entry of adult retinal stem cells and the differentiation of retinal neurons. However, how proliferative retinal progenitor cells perform a precise transition to postmitotic retinal cell types during the...
Source: Differentiation - April 17, 2023 Category: Research Authors: Wenjie Yin Xiying Mao Miao Xu Mingkang Chen Mengting Xue Na Su Songtao Yuan Qinghuai Liu Source Type: research

Epigenetic regulation in the commitment of progenitor cells during retinal development and regeneration
Differentiation. 2023 Apr 12:S0301-4681(23)00023-3. doi: 10.1016/j.diff.2023.04.002. Online ahead of print.ABSTRACTRetinal development is initiated by multipotent retinal progenitor cells, which undergo several rounds of cell divisions and subsequently terminal differentiation. Retinal regeneration is usually considered as the recapitulation of retinal development, which share common mechanisms underlying the cell cycle re-entry of adult retinal stem cells and the differentiation of retinal neurons. However, how proliferative retinal progenitor cells perform a precise transition to postmitotic retinal cell types during the...
Source: Differentiation - April 17, 2023 Category: Research Authors: Wenjie Yin Xiying Mao Miao Xu Mingkang Chen Mengting Xue Na Su Songtao Yuan Qinghuai Liu Source Type: research

Epigenetic regulation in the commitment of progenitor cells during retinal development and regeneration
Differentiation. 2023 Apr 12:S0301-4681(23)00023-3. doi: 10.1016/j.diff.2023.04.002. Online ahead of print.ABSTRACTRetinal development is initiated by multipotent retinal progenitor cells, which undergo several rounds of cell divisions and subsequently terminal differentiation. Retinal regeneration is usually considered as the recapitulation of retinal development, which share common mechanisms underlying the cell cycle re-entry of adult retinal stem cells and the differentiation of retinal neurons. However, how proliferative retinal progenitor cells perform a precise transition to postmitotic retinal cell types during the...
Source: Differentiation - April 17, 2023 Category: Research Authors: Wenjie Yin Xiying Mao Miao Xu Mingkang Chen Mengting Xue Na Su Songtao Yuan Qinghuai Liu Source Type: research

Reprogramming of trunk neural crest to a cranial crest-like identity alters their transcriptome and developmental potential
Differentiation. 2023 Apr 5;131:27-37. doi: 10.1016/j.diff.2023.04.001. Online ahead of print.ABSTRACTNeural crest cells along the body axis of avian embryos differ in their developmental potential, such that the cranial neural crest forms cartilage and bone whereas the trunk neural crest is unable to do so. Previous studies have identified a cranial crest-specific subcircuit that can imbue the trunk neural crest with the ability to form cartilage after grafting to the head. Here, we examine transcriptional and cell fate changes that accompany this reprogramming. First, we examined whether reprogrammed trunk neural crest m...
Source: Differentiation - April 14, 2023 Category: Research Authors: Sierra S Marable Marianne E Bronner Source Type: research

Reprogramming of trunk neural crest to a cranial crest-like identity alters their transcriptome and developmental potential
Differentiation. 2023 Apr 5;131:27-37. doi: 10.1016/j.diff.2023.04.001. Online ahead of print.ABSTRACTNeural crest cells along the body axis of avian embryos differ in their developmental potential, such that the cranial neural crest forms cartilage and bone whereas the trunk neural crest is unable to do so. Previous studies have identified a cranial crest-specific subcircuit that can imbue the trunk neural crest with the ability to form cartilage after grafting to the head. Here, we examine transcriptional and cell fate changes that accompany this reprogramming. First, we examined whether reprogrammed trunk neural crest m...
Source: Differentiation - April 14, 2023 Category: Research Authors: Sierra S Marable Marianne E Bronner Source Type: research

Reprogramming of trunk neural crest to a cranial crest-like identity alters their transcriptome and developmental potential
Differentiation. 2023 Apr 5;131:27-37. doi: 10.1016/j.diff.2023.04.001. Online ahead of print.ABSTRACTNeural crest cells along the body axis of avian embryos differ in their developmental potential, such that the cranial neural crest forms cartilage and bone whereas the trunk neural crest is unable to do so. Previous studies have identified a cranial crest-specific subcircuit that can imbue the trunk neural crest with the ability to form cartilage after grafting to the head. Here, we examine transcriptional and cell fate changes that accompany this reprogramming. First, we examined whether reprogrammed trunk neural crest m...
Source: Differentiation - April 14, 2023 Category: Research Authors: Sierra S Marable Marianne E Bronner Source Type: research

Characterizing the lens regeneration process in Pleurodeles waltl
CONCLUSIONS: Collectively, our results suggest that although lens regeneration capacity does not decline throughout the lifespan of newts, the intrinsic and extrinsic cellular changes associated with aging alter the kinetics of this process. By understanding how these changes affect lens regeneration in newts, we can gain important insights for restoring the age-related regeneration decline observed in most vertebrates.PMID:37055300 | DOI:10.1016/j.diff.2023.02.003 (Source: Differentiation)
Source: Differentiation - April 13, 2023 Category: Research Authors: Georgios Tsissios Gabriella Theodoroudis-Rapp Weihao Chen Anthony Sallese Byran Smucker Lake Ernst Junfan Chen Yiqi Xu Sophia Ratvasky Hui Wang Katia Del Rio-Tsonis Source Type: research