Stage-specific requirement for m < sup > 6 < /sup > A RNA methylation during cardiac differentiation of pluripotent stem cells
Differentiation. 2023 Jul 13;133:77-87. doi: 10.1016/j.diff.2023.07.001. Online ahead of print.ABSTRACTPrecise spatiotemporal control of gene expression patterns is critical for normal development. Pluripotent stem cells, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with the ability of unlimited self-renewal and differentiation into any cell type, provide a unique tool for understanding the underlying mechanism of development and disease in a dish. N6-methyl-adenosine (m6A) modification is the most extensive internal mRNA modification, which regulates almost all aspects of mRNA metaboli...
Source: Differentiation - July 28, 2023 Category: Research Authors: Shuai Dong Yuetong Sun Chang Liu Yanli Li Shanshan Yu Qi Zhang Yan Xu Source Type: research
Stage-specific requirement for m < sup > 6 < /sup > A RNA methylation during cardiac differentiation of pluripotent stem cells
Differentiation. 2023 Jul 13;133:77-87. doi: 10.1016/j.diff.2023.07.001. Online ahead of print.ABSTRACTPrecise spatiotemporal control of gene expression patterns is critical for normal development. Pluripotent stem cells, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with the ability of unlimited self-renewal and differentiation into any cell type, provide a unique tool for understanding the underlying mechanism of development and disease in a dish. N6-methyl-adenosine (m6A) modification is the most extensive internal mRNA modification, which regulates almost all aspects of mRNA metaboli...
Source: Differentiation - July 28, 2023 Category: Research Authors: Shuai Dong Yuetong Sun Chang Liu Yanli Li Shanshan Yu Qi Zhang Yan Xu Source Type: research
Stage-specific requirement for m < sup > 6 < /sup > A RNA methylation during cardiac differentiation of pluripotent stem cells
Differentiation. 2023 Jul 13;133:77-87. doi: 10.1016/j.diff.2023.07.001. Online ahead of print.ABSTRACTPrecise spatiotemporal control of gene expression patterns is critical for normal development. Pluripotent stem cells, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with the ability of unlimited self-renewal and differentiation into any cell type, provide a unique tool for understanding the underlying mechanism of development and disease in a dish. N6-methyl-adenosine (m6A) modification is the most extensive internal mRNA modification, which regulates almost all aspects of mRNA metaboli...
Source: Differentiation - July 28, 2023 Category: Research Authors: Shuai Dong Yuetong Sun Chang Liu Yanli Li Shanshan Yu Qi Zhang Yan Xu Source Type: research
Stage-specific requirement for m < sup > 6 < /sup > A RNA methylation during cardiac differentiation of pluripotent stem cells
Differentiation. 2023 Jul 13;133:77-87. doi: 10.1016/j.diff.2023.07.001. Online ahead of print.ABSTRACTPrecise spatiotemporal control of gene expression patterns is critical for normal development. Pluripotent stem cells, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with the ability of unlimited self-renewal and differentiation into any cell type, provide a unique tool for understanding the underlying mechanism of development and disease in a dish. N6-methyl-adenosine (m6A) modification is the most extensive internal mRNA modification, which regulates almost all aspects of mRNA metaboli...
Source: Differentiation - July 28, 2023 Category: Research Authors: Shuai Dong Yuetong Sun Chang Liu Yanli Li Shanshan Yu Qi Zhang Yan Xu Source Type: research
Stage-specific requirement for m < sup > 6 < /sup > A RNA methylation during cardiac differentiation of pluripotent stem cells
Differentiation. 2023 Jul 13;133:77-87. doi: 10.1016/j.diff.2023.07.001. Online ahead of print.ABSTRACTPrecise spatiotemporal control of gene expression patterns is critical for normal development. Pluripotent stem cells, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with the ability of unlimited self-renewal and differentiation into any cell type, provide a unique tool for understanding the underlying mechanism of development and disease in a dish. N6-methyl-adenosine (m6A) modification is the most extensive internal mRNA modification, which regulates almost all aspects of mRNA metaboli...
Source: Differentiation - July 28, 2023 Category: Research Authors: Shuai Dong Yuetong Sun Chang Liu Yanli Li Shanshan Yu Qi Zhang Yan Xu Source Type: research
Stage-specific requirement for m < sup > 6 < /sup > A RNA methylation during cardiac differentiation of pluripotent stem cells
Differentiation. 2023 Jul 13;133:77-87. doi: 10.1016/j.diff.2023.07.001. Online ahead of print.ABSTRACTPrecise spatiotemporal control of gene expression patterns is critical for normal development. Pluripotent stem cells, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with the ability of unlimited self-renewal and differentiation into any cell type, provide a unique tool for understanding the underlying mechanism of development and disease in a dish. N6-methyl-adenosine (m6A) modification is the most extensive internal mRNA modification, which regulates almost all aspects of mRNA metaboli...
Source: Differentiation - July 28, 2023 Category: Research Authors: Shuai Dong Yuetong Sun Chang Liu Yanli Li Shanshan Yu Qi Zhang Yan Xu Source Type: research
Stage-specific requirement for m < sup > 6 < /sup > A RNA methylation during cardiac differentiation of pluripotent stem cells
Differentiation. 2023 Jul 13;133:77-87. doi: 10.1016/j.diff.2023.07.001. Online ahead of print.ABSTRACTPrecise spatiotemporal control of gene expression patterns is critical for normal development. Pluripotent stem cells, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with the ability of unlimited self-renewal and differentiation into any cell type, provide a unique tool for understanding the underlying mechanism of development and disease in a dish. N6-methyl-adenosine (m6A) modification is the most extensive internal mRNA modification, which regulates almost all aspects of mRNA metaboli...
Source: Differentiation - July 28, 2023 Category: Research Authors: Shuai Dong Yuetong Sun Chang Liu Yanli Li Shanshan Yu Qi Zhang Yan Xu Source Type: research
Stage-specific requirement for m < sup > 6 < /sup > A RNA methylation during cardiac differentiation of pluripotent stem cells
Differentiation. 2023 Jul 13;133:77-87. doi: 10.1016/j.diff.2023.07.001. Online ahead of print.ABSTRACTPrecise spatiotemporal control of gene expression patterns is critical for normal development. Pluripotent stem cells, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with the ability of unlimited self-renewal and differentiation into any cell type, provide a unique tool for understanding the underlying mechanism of development and disease in a dish. N6-methyl-adenosine (m6A) modification is the most extensive internal mRNA modification, which regulates almost all aspects of mRNA metaboli...
Source: Differentiation - July 28, 2023 Category: Research Authors: Shuai Dong Yuetong Sun Chang Liu Yanli Li Shanshan Yu Qi Zhang Yan Xu Source Type: research
Stage-specific requirement for m < sup > 6 < /sup > A RNA methylation during cardiac differentiation of pluripotent stem cells
Differentiation. 2023 Jul 13;133:77-87. doi: 10.1016/j.diff.2023.07.001. Online ahead of print.ABSTRACTPrecise spatiotemporal control of gene expression patterns is critical for normal development. Pluripotent stem cells, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with the ability of unlimited self-renewal and differentiation into any cell type, provide a unique tool for understanding the underlying mechanism of development and disease in a dish. N6-methyl-adenosine (m6A) modification is the most extensive internal mRNA modification, which regulates almost all aspects of mRNA metaboli...
Source: Differentiation - July 28, 2023 Category: Research Authors: Shuai Dong Yuetong Sun Chang Liu Yanli Li Shanshan Yu Qi Zhang Yan Xu Source Type: research
Stage-specific requirement for m < sup > 6 < /sup > A RNA methylation during cardiac differentiation of pluripotent stem cells
Differentiation. 2023 Jul 13;133:77-87. doi: 10.1016/j.diff.2023.07.001. Online ahead of print.ABSTRACTPrecise spatiotemporal control of gene expression patterns is critical for normal development. Pluripotent stem cells, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with the ability of unlimited self-renewal and differentiation into any cell type, provide a unique tool for understanding the underlying mechanism of development and disease in a dish. N6-methyl-adenosine (m6A) modification is the most extensive internal mRNA modification, which regulates almost all aspects of mRNA metaboli...
Source: Differentiation - July 28, 2023 Category: Research Authors: Shuai Dong Yuetong Sun Chang Liu Yanli Li Shanshan Yu Qi Zhang Yan Xu Source Type: research
Stage-specific requirement for m < sup > 6 < /sup > A RNA methylation during cardiac differentiation of pluripotent stem cells
Differentiation. 2023 Jul 13;133:77-87. doi: 10.1016/j.diff.2023.07.001. Online ahead of print.ABSTRACTPrecise spatiotemporal control of gene expression patterns is critical for normal development. Pluripotent stem cells, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with the ability of unlimited self-renewal and differentiation into any cell type, provide a unique tool for understanding the underlying mechanism of development and disease in a dish. N6-methyl-adenosine (m6A) modification is the most extensive internal mRNA modification, which regulates almost all aspects of mRNA metaboli...
Source: Differentiation - July 28, 2023 Category: Research Authors: Shuai Dong Yuetong Sun Chang Liu Yanli Li Shanshan Yu Qi Zhang Yan Xu Source Type: research
Stage-specific requirement for m < sup > 6 < /sup > A RNA methylation during cardiac differentiation of pluripotent stem cells
Differentiation. 2023 Jul 13;133:77-87. doi: 10.1016/j.diff.2023.07.001. Online ahead of print.ABSTRACTPrecise spatiotemporal control of gene expression patterns is critical for normal development. Pluripotent stem cells, including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), with the ability of unlimited self-renewal and differentiation into any cell type, provide a unique tool for understanding the underlying mechanism of development and disease in a dish. N6-methyl-adenosine (m6A) modification is the most extensive internal mRNA modification, which regulates almost all aspects of mRNA metaboli...
Source: Differentiation - July 28, 2023 Category: Research Authors: Shuai Dong Yuetong Sun Chang Liu Yanli Li Shanshan Yu Qi Zhang Yan Xu Source Type: research
Intravitreal injection of FGF and TGF- β inhibitors disrupts cranial cartilage development
This study adds to the foundational knowledge about condensation induction of cranial cartilage development and provides insight into the timing and signaling involved in the early development of several craniofacial cartilage elements in zebrafish.PMID:37481903 | DOI:10.1016/j.diff.2023.07.003 (Source: Differentiation)
Source: Differentiation - July 23, 2023 Category: Research Authors: Nicholas W Zinck Shea J L McInnis Tamara A Franz-Odendaal Source Type: research
Sonic hedgehog signaling in craniofacial development
This article provides a summary of the major findings in studies of the roles of SHH signaling in craniofacial development, with emphasis on recent advances in the understanding of the molecular and cellular mechanisms regulating the SHH signaling pathway activity and those involving SHH signaling in the formation and patterning of craniofacial structures.PMID:37481904 | DOI:10.1016/j.diff.2023.07.002 (Source: Differentiation)
Source: Differentiation - July 23, 2023 Category: Research Authors: Jingyue Xu Paul P R Iyyanar Yu Lan Rulang Jiang Source Type: research
Intravitreal injection of FGF and TGF- β inhibitors disrupts cranial cartilage development
This study adds to the foundational knowledge about condensation induction of cranial cartilage development and provides insight into the timing and signaling involved in the early development of several craniofacial cartilage elements in zebrafish.PMID:37481903 | DOI:10.1016/j.diff.2023.07.003 (Source: Differentiation)
Source: Differentiation - July 23, 2023 Category: Research Authors: Nicholas W Zinck Shea J L McInnis Tamara A Franz-Odendaal Source Type: research
