The road to gene manipulation in the mouse: Jean Brachet Memorial Lecture of the International Society of Differentiation (delivered June 21, 2023  at Cold Spring Harbor Laboratory)
This article details various threads of research and the central role of the laboratory mouse that came together in reaching this point, all from the perspective of a scientist whose research was deeply immersed in the field.PMID:38330622 | DOI:10.1016/j.diff.2024.100753 (Source: Differentiation)
Source: Differentiation - February 8, 2024 Category: Research Authors: Virginia Papaioannou Source Type: research

The road to gene manipulation in the mouse: Jean Brachet Memorial Lecture of the International Society of Differentiation (delivered June 21, 2023  at Cold Spring Harbor Laboratory)
This article details various threads of research and the central role of the laboratory mouse that came together in reaching this point, all from the perspective of a scientist whose research was deeply immersed in the field.PMID:38330622 | DOI:10.1016/j.diff.2024.100753 (Source: Differentiation)
Source: Differentiation - February 8, 2024 Category: Research Authors: Virginia Papaioannou Source Type: research

The road to gene manipulation in the mouse: Jean Brachet Memorial Lecture of the International Society of Differentiation (delivered June 21, 2023  at Cold Spring Harbor Laboratory)
This article details various threads of research and the central role of the laboratory mouse that came together in reaching this point, all from the perspective of a scientist whose research was deeply immersed in the field.PMID:38330622 | DOI:10.1016/j.diff.2024.100753 (Source: Differentiation)
Source: Differentiation - February 8, 2024 Category: Research Authors: Virginia Papaioannou Source Type: research

The road to gene manipulation in the mouse: Jean Brachet Memorial Lecture of the International Society of Differentiation (delivered June 21, 2023  at Cold Spring Harbor Laboratory)
This article details various threads of research and the central role of the laboratory mouse that came together in reaching this point, all from the perspective of a scientist whose research was deeply immersed in the field.PMID:38330622 | DOI:10.1016/j.diff.2024.100753 (Source: Differentiation)
Source: Differentiation - February 8, 2024 Category: Research Authors: Virginia Papaioannou Source Type: research

Regulation of adipogenesis by histone methyltransferases
Differentiation. 2024 Jan 14;136:100746. doi: 10.1016/j.diff.2024.100746. Online ahead of print.ABSTRACTEpigenetic regulation is a critical component of lineage determination. Adipogenesis is the process through which uncommitted stem cells or adipogenic precursor cells differentiate into adipocytes, the most abundant cell type of the adipose tissue. Studies examining chromatin modification during adipogenesis have provided further understanding of the molecular blueprint that controls the onset of adipogenic differentiation. Unlike histone acetylation, histone methylation has context dependent effects on the activity of a...
Source: Differentiation - January 19, 2024 Category: Research Authors: Yuanxiang Zhao Zachary Skovgaard Qinyi Wang Source Type: research

BBS genes are involved in accelerated proliferation and early differentiation of BBS-related tissues
In conclusions, the BBS4 gene plays a significant, similar and global role in the cellular proliferation of various BBS related tissues. These results highlight the universal role of the BBS gene in the cell cycle, and further deepen the knowledge of the mechanisms underlying the development of BBS.PMID:38215537 | DOI:10.1016/j.diff.2024.100745 (Source: Differentiation)
Source: Differentiation - January 12, 2024 Category: Research Authors: Avital Horwitz Noa Levi-Carmel Olga Shnaider Ruth Birk Source Type: research

Expression patterns of CYP26A1, FGF8, CDKN1A, and NPVF in the developing rhesus monkey retina
Differentiation. 2024 Jan-Feb;135:100743. doi: 10.1016/j.diff.2023.100743. Epub 2023 Dec 14.ABSTRACTThe fovea centralis (fovea) is a specialized region of the primate retina that plays crucial roles in high-resolution visual acuity and color perception. The fovea is characterized by a high density of cone photoreceptors and no rods, and unique anatomical properties that contribute to its remarkable visual capabilities. Early histological analyses identified some of the key events that contribute to foveal development, but the mechanisms that direct the specification of this area are not understood. Recently, the expression...
Source: Differentiation - December 26, 2023 Category: Research Authors: Miranda R Krueger Elizabeth Fishman-Williams Sergi Sim ó Alice F Tarantal Anna La Torre Source Type: research

Expression patterns of CYP26A1, FGF8, CDKN1A, and NPVF in the developing rhesus monkey retina
Differentiation. 2023 Dec 14;135:100743. doi: 10.1016/j.diff.2023.100743. Online ahead of print.ABSTRACTThe fovea centralis (fovea) is a specialized region of the primate retina that plays crucial roles in high-resolution visual acuity and color perception. The fovea is characterized by a high density of cone photoreceptors and no rods, and unique anatomical properties that contribute to its remarkable visual capabilities. Early histological analyses identified some of the key events that contribute to foveal development, but the mechanisms that direct the specification of this area are not understood. Recently, the expres...
Source: Differentiation - December 26, 2023 Category: Research Authors: Miranda R Krueger Elizabeth Fishman-Williams Sergi Sim ó Alice F Tarantal Anna La Torre Source Type: research

Expression patterns of CYP26A1, FGF8, CDKN1A, and NPVF in the developing rhesus monkey retina
Differentiation. 2023 Dec 14;135:100743. doi: 10.1016/j.diff.2023.100743. Online ahead of print.ABSTRACTThe fovea centralis (fovea) is a specialized region of the primate retina that plays crucial roles in high-resolution visual acuity and color perception. The fovea is characterized by a high density of cone photoreceptors and no rods, and unique anatomical properties that contribute to its remarkable visual capabilities. Early histological analyses identified some of the key events that contribute to foveal development, but the mechanisms that direct the specification of this area are not understood. Recently, the expres...
Source: Differentiation - December 26, 2023 Category: Research Authors: Miranda R Krueger Elizabeth Fishman-Williams Sergi Sim ó Alice F Tarantal Anna La Torre Source Type: research

Expression patterns of CYP26A1, FGF8, CDKN1A, and NPVF in the developing rhesus monkey retina
Differentiation. 2023 Dec 14;135:100743. doi: 10.1016/j.diff.2023.100743. Online ahead of print.ABSTRACTThe fovea centralis (fovea) is a specialized region of the primate retina that plays crucial roles in high-resolution visual acuity and color perception. The fovea is characterized by a high density of cone photoreceptors and no rods, and unique anatomical properties that contribute to its remarkable visual capabilities. Early histological analyses identified some of the key events that contribute to foveal development, but the mechanisms that direct the specification of this area are not understood. Recently, the expres...
Source: Differentiation - December 26, 2023 Category: Research Authors: Miranda R Krueger Elizabeth Fishman-Williams Sergi Sim ó Alice F Tarantal Anna La Torre Source Type: research

Expression patterns of CYP26A1, FGF8, CDKN1A, and NPVF in the developing rhesus monkey retina
Differentiation. 2023 Dec 14;135:100743. doi: 10.1016/j.diff.2023.100743. Online ahead of print.ABSTRACTThe fovea centralis (fovea) is a specialized region of the primate retina that plays crucial roles in high-resolution visual acuity and color perception. The fovea is characterized by a high density of cone photoreceptors and no rods, and unique anatomical properties that contribute to its remarkable visual capabilities. Early histological analyses identified some of the key events that contribute to foveal development, but the mechanisms that direct the specification of this area are not understood. Recently, the expres...
Source: Differentiation - December 26, 2023 Category: Research Authors: Miranda R Krueger Elizabeth Fishman-Williams Sergi Sim ó Alice F Tarantal Anna La Torre Source Type: research

Expression patterns of CYP26A1, FGF8, CDKN1A, and NPVF in the developing rhesus monkey retina
Differentiation. 2023 Dec 14;135:100743. doi: 10.1016/j.diff.2023.100743. Online ahead of print.ABSTRACTThe fovea centralis (fovea) is a specialized region of the primate retina that plays crucial roles in high-resolution visual acuity and color perception. The fovea is characterized by a high density of cone photoreceptors and no rods, and unique anatomical properties that contribute to its remarkable visual capabilities. Early histological analyses identified some of the key events that contribute to foveal development, but the mechanisms that direct the specification of this area are not understood. Recently, the expres...
Source: Differentiation - December 26, 2023 Category: Research Authors: Miranda R Krueger Elizabeth Fishman-Williams Sergi Sim ó Alice F Tarantal Anna La Torre Source Type: research

Expression patterns of CYP26A1, FGF8, CDKN1A, and NPVF in the developing rhesus monkey retina
Differentiation. 2023 Dec 14;135:100743. doi: 10.1016/j.diff.2023.100743. Online ahead of print.ABSTRACTThe fovea centralis (fovea) is a specialized region of the primate retina that plays crucial roles in high-resolution visual acuity and color perception. The fovea is characterized by a high density of cone photoreceptors and no rods, and unique anatomical properties that contribute to its remarkable visual capabilities. Early histological analyses identified some of the key events that contribute to foveal development, but the mechanisms that direct the specification of this area are not understood. Recently, the expres...
Source: Differentiation - December 26, 2023 Category: Research Authors: Miranda R Krueger Elizabeth Fishman-Williams Sergi Sim ó Alice F Tarantal Anna La Torre Source Type: research

Expression patterns of CYP26A1, FGF8, CDKN1A, and NPVF in the developing rhesus monkey retina
Differentiation. 2023 Dec 14;135:100743. doi: 10.1016/j.diff.2023.100743. Online ahead of print.ABSTRACTThe fovea centralis (fovea) is a specialized region of the primate retina that plays crucial roles in high-resolution visual acuity and color perception. The fovea is characterized by a high density of cone photoreceptors and no rods, and unique anatomical properties that contribute to its remarkable visual capabilities. Early histological analyses identified some of the key events that contribute to foveal development, but the mechanisms that direct the specification of this area are not understood. Recently, the expres...
Source: Differentiation - December 26, 2023 Category: Research Authors: Miranda R Krueger Elizabeth Fishman-Williams Sergi Sim ó Alice F Tarantal Anna La Torre Source Type: research

Expression patterns of CYP26A1, FGF8, CDKN1A, and NPVF in the developing rhesus monkey retina
Differentiation. 2023 Dec 14;135:100743. doi: 10.1016/j.diff.2023.100743. Online ahead of print.ABSTRACTThe fovea centralis (fovea) is a specialized region of the primate retina that plays crucial roles in high-resolution visual acuity and color perception. The fovea is characterized by a high density of cone photoreceptors and no rods, and unique anatomical properties that contribute to its remarkable visual capabilities. Early histological analyses identified some of the key events that contribute to foveal development, but the mechanisms that direct the specification of this area are not understood. Recently, the expres...
Source: Differentiation - December 26, 2023 Category: Research Authors: Miranda R Krueger Elizabeth Fishman-Williams Sergi Sim ó Alice F Tarantal Anna La Torre Source Type: research