Pregnancy and breastfeeding in women with multiple sclerosis
Nervenarzt. 2024 Feb 23. doi: 10.1007/s00115-024-01621-9. Online ahead of print.ABSTRACTThe diagnosis of multiple sclerosis (MS) in women of reproductive age is associated with many uncertainties regarding childbearing and lactation. Pregnancies of MS patients are not usually considered high-risk pregnancies per se. The likelihood of pregnancy complications or adverse pregnancy outcomes is not increased by the disease; however, a careful planning of pregnancy is important in order to choose the treatment option with the greatest benefit for the mother and the least possible risk for the baby. For highly active courses of t...
Source: Der Nervenarzt - February 23, 2024 Category: Neurology Authors: Laura Witt Sandra Thiel Kerstin Hellwig Source Type: research

Premenstrual syndrome and premenstrual dysphoric disorder-Overview on pathophysiology, diagnostics and treatment
Nervenarzt. 2024 Feb 23. doi: 10.1007/s00115-024-01625-5. Online ahead of print.ABSTRACTPremenstrual syndrome and premenstrual dysphoric disorder become episodically manifest during the second half of the female menstrual cycle and are characterized by psychological and physical symptoms causing relevant functional and social impairments. Mood swings, depression and dysphoria are associated depressive symptoms. Therefore, affective disorders should be considered as a differential diagnosis. Of women in reproductive age 3-8% suffer from premenstrual syndrome and 2% of women are affected by premenstrual dysphoric disorder. G...
Source: Der Nervenarzt - February 23, 2024 Category: Neurology Authors: Jana Hau ßmann M Goeckenjan R Hau ßmann P Wimberger Source Type: research

Pregnancy and breastfeeding in women with multiple sclerosis
Nervenarzt. 2024 Feb 23. doi: 10.1007/s00115-024-01621-9. Online ahead of print.ABSTRACTThe diagnosis of multiple sclerosis (MS) in women of reproductive age is associated with many uncertainties regarding childbearing and lactation. Pregnancies of MS patients are not usually considered high-risk pregnancies per se. The likelihood of pregnancy complications or adverse pregnancy outcomes is not increased by the disease; however, a careful planning of pregnancy is important in order to choose the treatment option with the greatest benefit for the mother and the least possible risk for the baby. For highly active courses of t...
Source: Der Nervenarzt - February 23, 2024 Category: Neurology Authors: Laura Witt Sandra Thiel Kerstin Hellwig Source Type: research

Premenstrual syndrome and premenstrual dysphoric disorder-Overview on pathophysiology, diagnostics and treatment
Nervenarzt. 2024 Feb 23. doi: 10.1007/s00115-024-01625-5. Online ahead of print.ABSTRACTPremenstrual syndrome and premenstrual dysphoric disorder become episodically manifest during the second half of the female menstrual cycle and are characterized by psychological and physical symptoms causing relevant functional and social impairments. Mood swings, depression and dysphoria are associated depressive symptoms. Therefore, affective disorders should be considered as a differential diagnosis. Of women in reproductive age 3-8% suffer from premenstrual syndrome and 2% of women are affected by premenstrual dysphoric disorder. G...
Source: Der Nervenarzt - February 23, 2024 Category: Neurology Authors: Jana Hau ßmann M Goeckenjan R Hau ßmann P Wimberger Source Type: research

Pregnancy and breastfeeding in women with multiple sclerosis
Nervenarzt. 2024 Feb 23. doi: 10.1007/s00115-024-01621-9. Online ahead of print.ABSTRACTThe diagnosis of multiple sclerosis (MS) in women of reproductive age is associated with many uncertainties regarding childbearing and lactation. Pregnancies of MS patients are not usually considered high-risk pregnancies per se. The likelihood of pregnancy complications or adverse pregnancy outcomes is not increased by the disease; however, a careful planning of pregnancy is important in order to choose the treatment option with the greatest benefit for the mother and the least possible risk for the baby. For highly active courses of t...
Source: Der Nervenarzt - February 23, 2024 Category: Neurology Authors: Laura Witt Sandra Thiel Kerstin Hellwig Source Type: research

Diagnosis and admission center : Establishment and evaluation of an integrated translational infrastructure for clinical psychiatric research
We report here on the establishment of the Diagnosis and Admission Center (DAZ) at the Central Institute of Mental Health (ZI) in Mannheim. The DAZ is an outpatient unit upstream of other care structures for clinical and scientific phenotyping across diagnoses as a starting point for data-driven, individualized pathways to further treatment, diagnostics or research. We describe the functions, goals, and implementation of the newly created clinical scientific translational structure, provide an overview of the patient populations it has reached, and provide data on its acceptance. In this context, the close integration with...
Source: Der Nervenarzt - February 21, 2024 Category: Neurology Authors: Urs Braun Oliver Hennig Johanna Forstner Sarah Gerhardt Mirjam Deffaa DAZ-Team (die Mitglieder sind am Beitragsende aufgelistet) Dusan Hirjak Michael Deuschle Anne Koopmann Christian Wisch Melanie Fritz Gabriele Ende Heike Tost Peter Sch öfer Stefan Bisc Source Type: research

Diagnosis and admission center : Establishment and evaluation of an integrated translational infrastructure for clinical psychiatric research
We report here on the establishment of the Diagnosis and Admission Center (DAZ) at the Central Institute of Mental Health (ZI) in Mannheim. The DAZ is an outpatient unit upstream of other care structures for clinical and scientific phenotyping across diagnoses as a starting point for data-driven, individualized pathways to further treatment, diagnostics or research. We describe the functions, goals, and implementation of the newly created clinical scientific translational structure, provide an overview of the patient populations it has reached, and provide data on its acceptance. In this context, the close integration with...
Source: Der Nervenarzt - February 21, 2024 Category: Neurology Authors: Urs Braun Oliver Hennig Johanna Forstner Sarah Gerhardt Mirjam Deffaa DAZ-Team (die Mitglieder sind am Beitragsende aufgelistet) Dusan Hirjak Michael Deuschle Anne Koopmann Christian Wisch Melanie Fritz Gabriele Ende Heike Tost Peter Sch öfer Stefan Bisc Source Type: research

Genetic studies on forensic-psychiatric inpatients? : Clinical, ethical and legal considerations
CONCLUSION: Including criminally detained study participants can be ethically and legally justified when autonomous consent is supported by specific organizational and legal procedures and measures, for example via a clear professional and organizational separation of correction and research.PMID:38372772 | DOI:10.1007/s00115-024-01624-6 (Source: Der Nervenarzt)
Source: Der Nervenarzt - February 19, 2024 Category: Neurology Authors: Jan Bulla Josef Franz Lindner Daniela Mier Thomas G Schulze Fanny Senner Kerstin Schl ögl-Flierl Source Type: research

Genetic studies on forensic-psychiatric inpatients? : Clinical, ethical and legal considerations
CONCLUSION: Including criminally detained study participants can be ethically and legally justified when autonomous consent is supported by specific organizational and legal procedures and measures, for example via a clear professional and organizational separation of correction and research.PMID:38372772 | DOI:10.1007/s00115-024-01624-6 (Source: Der Nervenarzt)
Source: Der Nervenarzt - February 19, 2024 Category: Neurology Authors: Jan Bulla Josef Franz Lindner Daniela Mier Thomas G Schulze Fanny Senner Kerstin Schl ögl-Flierl Source Type: research

Genetic studies on forensic-psychiatric inpatients? : Clinical, ethical and legal considerations
CONCLUSION: Including criminally detained study participants can be ethically and legally justified when autonomous consent is supported by specific organizational and legal procedures and measures, for example via a clear professional and organizational separation of correction and research.PMID:38372772 | DOI:10.1007/s00115-024-01624-6 (Source: Der Nervenarzt)
Source: Der Nervenarzt - February 19, 2024 Category: Neurology Authors: Jan Bulla Josef Franz Lindner Daniela Mier Thomas G Schulze Fanny Senner Kerstin Schl ögl-Flierl Source Type: research

Jon Fosse: "Melancholy"-A  reading from a psychiatric perspective
Nervenarzt. 2024 Feb 16. doi: 10.1007/s00115-024-01623-7. Online ahead of print.NO ABSTRACTPMID:38366122 | DOI:10.1007/s00115-024-01623-7 (Source: Der Nervenarzt)
Source: Der Nervenarzt - February 17, 2024 Category: Neurology Authors: Katharina Domschke Dieter Ebert Source Type: research

Jon Fosse: "Melancholy"-A  reading from a psychiatric perspective
Nervenarzt. 2024 Feb 16. doi: 10.1007/s00115-024-01623-7. Online ahead of print.NO ABSTRACTPMID:38366122 | DOI:10.1007/s00115-024-01623-7 (Source: Der Nervenarzt)
Source: Der Nervenarzt - February 17, 2024 Category: Neurology Authors: Katharina Domschke Dieter Ebert Source Type: research

Interpretation of a  concept for functional movement disorders from the perspective of older patients
Nervenarzt. 2024 Feb 15. doi: 10.1007/s00115-024-01614-8. Online ahead of print.ABSTRACTA recently published concept considers a significant proportion of the occurrence and persistence of functional movement disorders (FMD) to be explained by increased/incorrect weighting of the expected movement (feedforward signal) in the presence of decreased/altered actual feedback of the movement. In the context of aging and age-associated diseases, there is an increased likelihood that these prerequisites will occur, also in combination. For example, the feedforward signal can be enhanced by accumulation of a wealth of experience bu...
Source: Der Nervenarzt - February 16, 2024 Category: Neurology Authors: Walter Maetzler Johanna Geritz Lina Stagneth Kirsten Emmert Source Type: research

Depression in the field of tension of gender roles
This article summarizes information that was considered particularly relevant in the interdisciplinary dialogue regarding possible explanatory factors for gender differences in depressive disorders.RESULTS: The summarized studies indicate that women and men differ in certain aspects of stress processing and trauma exposure but men do not have a lower risk of disease as a result. On the contrary, the frequency of depressive disorders in men seems to be underestimated due to an atypical symptom manifestation.DISCUSSION: The implementation of knowledge about gender-specific vulnerability in the training of physicians and psyc...
Source: Der Nervenarzt - February 16, 2024 Category: Neurology Authors: Eva Friedel Ingar Abels Gina-Isabelle Henze Stephanie Haering Pichit Buspavanich Turu Stadler Source Type: research

Understanding and explaining functional movement disorders
Nervenarzt. 2024 Feb 16. doi: 10.1007/s00115-024-01619-3. Online ahead of print.ABSTRACTFunctional movement disorders are not uncommon in neurological consultations, hospitals and emergency departments. Although the disorder can usually be recognized clinically, the communication of the diagnosis is often unsatisfactory. Those affected are indirectly accused of a lack of insight or openness but it is often the doctors who fail to formulate a coherent and comprehensible explanation of the underlying disorder. In this review an integrative model for the development of functional movement disorders is presented, which places ...
Source: Der Nervenarzt - February 16, 2024 Category: Neurology Authors: Stoyan Popkirov Johannes Jungilligens Rosa Michaelis Source Type: research