[Erratum to: The prevalence of people with dementia in Germany-A  nationwide analysis at the district level].
[Erratum to: The prevalence of people with dementia in Germany-A nationwide analysis at the district level]. Nervenarzt. 2020 Aug 18;: Authors: Thyrian JR, Boekholt M, Hoffmann W, Leiz M, Monsees J, Schmachtenberg T, Schumacher-Schönert F, Stentzel U PMID: 32809037 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - August 17, 2020 Category: Neurology Authors: Thyrian JR, Boekholt M, Hoffmann W, Leiz M, Monsees J, Schmachtenberg T, Schumacher-Schönert F, Stentzel U Tags: Nervenarzt Source Type: research

[Structures of endovascular recanalization in Germany : Cross-sectional survey of certified stroke units 2016-2018].
Abstract In this cross-sectional study data from 299 certified stroke units (SU) in Germany were analyzed from January 2016 to December 2018 and included comprehensive stroke centers (CSC 34%), local SU (62%), and telemedical SU (4%). In a total of 2487 SU monitor beds, 251,539 cases of stroke treatment were documented. The number of monitor beds (10.8 vs. 7.2) and stroke cases per year (1143 vs. 708) were significantly higher in CSC than in local SU. A total of 9251 endovascular recanalization (ER) procedures were performed annually by 475 interventionalists. The overall rate of ER was 3.7% of all strok...
Source: Der Nervenarzt - August 17, 2020 Category: Neurology Authors: Nabavi DG, Busse O Tags: Nervenarzt Source Type: research

[Discharge management in pediatric and adolescent psychiatry : Expectations and realities from the parental perspective].
CONCLUSION: From the perspective of affected families a proactive early individual and reliable care coordination by a constant contact person is essential for a good discharge management. PMID: 32780169 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - August 10, 2020 Category: Neurology Authors: Boege I, Williams B, Schulze U, Fegert JM Tags: Nervenarzt Source Type: research

[Emma Wilson Mooers (1858-1911): the neuropathologist at Aloys Alzheimer's side].
l H PMID: 32780170 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - August 10, 2020 Category: Neurology Authors: Förstl H Tags: Nervenarzt Source Type: research

[Spiritual competence in psychiatry and psychotherapy-Barriers and success factors].
g A PMID: 32776233 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - August 9, 2020 Category: Neurology Authors: Frick E, Ziemer P, Heres S, Ableidinger K, Pfitzer F, Büssing A Tags: Nervenarzt Source Type: research

[Weaning in neurological and neurosurgical early rehabilitation-Results from the "WennFr üh" study of the German Society for Neurorehabilitation].
[Weaning in neurological and neurosurgical early rehabilitation-Results from the "WennFrüh" study of the German Society for Neurorehabilitation]. Nervenarzt. 2020 Aug 10;: Authors: Rollnik JD, Brocke J, Gorsler A, Groß M, Hartwich M, Pohl M, Schmidt-Wilcke T, Platz T Abstract Neurological and neurosurgical early rehabilitation patients are often so critically ill that they must be weaned from mechanical ventilation in addition to early rehabilitative treatment. The German Society for Neurorehabilitation (DGNR) carried out a survey and asked neurological weaning units to provi...
Source: Der Nervenarzt - August 9, 2020 Category: Neurology Authors: Rollnik JD, Brocke J, Gorsler A, Groß M, Hartwich M, Pohl M, Schmidt-Wilcke T, Platz T Tags: Nervenarzt Source Type: research

[Effectiveness, efficiency and safety of stroke telemedicine in times of the coronavirus pandemic : The "case" Thuringia].
[Effectiveness, efficiency and safety of stroke telemedicine in times of the coronavirus pandemic : The "case" Thuringia]. Nervenarzt. 2020 Aug 03;: Authors: Klingner CC, Brodoehl S, Wagner F, Berrouschot J, Günther A, Witte OW, Klingner CM PMID: 32747988 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - August 2, 2020 Category: Neurology Authors: Klingner CC, Brodoehl S, Wagner F, Berrouschot J, Günther A, Witte OW, Klingner CM Tags: Nervenarzt Source Type: research

[Nocebo, informed consent and doctor-patient communication].
Abstract Negative previous experiences (conditioning), observational learning and expectations can trigger nocebo effects. They are responsible for a substantial proportion of the side effects of medical treatment, and are induced primarily by risk information for informed consent. This has been demonstrated in studies on patient groups with or without modified medical information. Drug trials in the field of neurology and psychiatry have regularly revealed side effects and drop-out also in placebo groups. The underlying neurobiological mechanisms were experimentally investigated especially for nocebo-induced hype...
Source: Der Nervenarzt - July 28, 2020 Category: Neurology Authors: Hansen E, Zech N, Benson S Tags: Nervenarzt Source Type: research

[Young onset dementia].
CONCLUSION: The diagnostics of primary neurodegenerative diseases have continuously improved, especially due to the availability of an increasing number of clinical, molecular and imaging biomarkers. Nevertheless, in order to avoid unnecessary and burdensome examinations, the diagnostic work-up of young onset dementia must be hypothesis-driven, i.e. following a precise clinical syndromic classification of the symptoms. PMID: 32725488 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - July 27, 2020 Category: Neurology Authors: Pawlowski M, Johnen A, Duning T Tags: Nervenarzt Source Type: research

[Erratum to: Ocrelizumab for treatment of multiple sclerosis].
PMID: 32725489 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - July 27, 2020 Category: Neurology Authors: Graf J, Albrecht P, Goebels N, Aktas O, Hartung HP Tags: Nervenarzt Source Type: research

[Psychosocial therapy in psychiatry : Update of the DGPPN-S3 guidelines "Psychosocial therapies for severe mental illnesses"].
CONCLUSION: The successful implementation of guidelines depends not only on the quality but also on the dissemination. Therefore, in addition to the treatment guidelines a short version, a patient version and a waiting room version were developed. PMID: 32725490 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - July 27, 2020 Category: Neurology Authors: Gühne U, Weinmann S, Becker T, Riedel-Heller SG Tags: Nervenarzt Source Type: research

[Suicide stigma and suicide prevention].
h N Abstract In many societies suicide was and is an extremely controversial topic. This review article outlines the historical background of social condemnation of suicidal thoughts and actions in the western world. It summarizes current research results about the consequences of suicide stigma for affected persons and its relevance for suicide prevention. Finally, the next steps in research and prevention are discussed. Over time and in different cultures, the societal judgement of suicide has greatly varied. During antiquity, some philosophers viewed suicide negatively and by the fifth century AD suicide was wi...
Source: Der Nervenarzt - July 27, 2020 Category: Neurology Authors: Oexle N, Mayer L, Rüsch N Tags: Nervenarzt Source Type: research

[Granulomatosis with polyangiitis and neurological disease onset].
PMID: 32725492 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - July 27, 2020 Category: Neurology Authors: Ellwardt E, Birklein F Tags: Nervenarzt Source Type: research

[Post-seclusion/post-restraint debriefing with patients-overview and current situation].
CONCLUSION: Structured post-seclusion/post-restraint debriefings with patients constitute a possible intervention to reduce coercive measures, but as of now there is little scientific evidence for the efficacy. Incorporating them into complex therapeutic treatment concepts for ward programs appears to be meaningful. PMID: 32725493 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - July 27, 2020 Category: Neurology Authors: Krieger E, Fischer R, Moritz S, Nagel M Tags: Nervenarzt Source Type: research

[Overlap syndrome between primary T cell-mediated vasculitis of the brainstem and chronic lymphocytic inflammation with pontocerebellar perivascular enhancement responsive to steroids (CLIPPERS)].
Seidel G PMID: 32719927 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - July 26, 2020 Category: Neurology Authors: Scharlibbe LM, Schöps C, Heßelmann V, Friese M, Seidel G Tags: Nervenarzt Source Type: research

[The COVID-19 pandemic has not changed the number but the type of psychiatric emergencies : A  comparison of care data between 2019 and 2020].
[The COVID-19 pandemic has not changed the number but the type of psychiatric emergencies : A comparison of care data between 2019 and 2020]. Nervenarzt. 2020 Jul 24;: Authors: Aly L, Sondergeld R, Hölzle P, Frank A, Knier B, Pausch E, Dommasch M, Förstl H, Fatke B PMID: 32710149 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - July 23, 2020 Category: Neurology Authors: Aly L, Sondergeld R, Hölzle P, Frank A, Knier B, Pausch E, Dommasch M, Förstl H, Fatke B Tags: Nervenarzt Source Type: research

[Irreversible loss of brain function-Part 1: pitfalls in clinical diagnosis].
Abstract A significant change in the fourth update of the German guidelines on determining brain death is that it includes an explicit profile of requirements on physicians involved in ILBF diagnosis. These requisite qualification criteria have also been formulated due to the fact that, in many hospitals, ILBF diagnosis is only rarely carried out and, as a result, uncertainty frequently arises. Typical difficulties emerge at all stages of ILBF diagnosis, and numerous relevant pitfalls arise that need to be taken into consideration and which might also be relevant in the selection of the method(s) to detect irrever...
Source: Der Nervenarzt - July 22, 2020 Category: Neurology Authors: Janzen RWC, Lambeck J, Niesen WD, Erbguth F Tags: Nervenarzt Source Type: research

[Pharmacotherapy of alcohol withdrawal: update and new developments].
r S Abstract So far few medications are approved for prophylactic treatment of alcohol dependence relapse. Apart from disulfiram, which is no longer marketed in Germany, the opioid antagonists naltrexone, nalmefene and the putative glutamate antagonist acamprosate are approved. In some other countries, baclofen and gamma-hydroxybutyrate (GHB) are licensed. Possible other drugs of interest for prophylaxis of alcohol dependence relapse are vareniclin, gabapentin, and topiramate, but so far none of them have received approval. In the light of the currently running revision of the German guidelines for the diagnosis a...
Source: Der Nervenarzt - July 20, 2020 Category: Neurology Authors: Soyka M, Rösner S Tags: Nervenarzt Source Type: research

[Headache in multiple sclerosis].
Abstract The relationship between headache and multiple sclerosis (MS) has been a matter of controversy for over 60 years. Headaches are still rated as a "red flag", indicating alternative diagnoses to MS, although in the last few years numerous studies have shown a frequent association between headache and MS. In recent studies on MS patients, a link was found between lower age/shorter disease duration of MS and frequent headaches. A study of 50 patients manifesting MS for the first time showed the highest headache prevalence in MS of 78% reported so far.Headaches can also be a&...
Source: Der Nervenarzt - July 20, 2020 Category: Neurology Authors: Gebhardt M, Kropp P, Hoffmann F, Zettl UK Tags: Nervenarzt Source Type: research

[Appearances are not deceptive: clinical evidence and new research approaches to open-label placebo].
Abstract The efficacy of placebo effects is proven in experimental, clinical and meta-analytical studies. However, harnessing placebo effects in clinical treatment contexts is hampered legally and ethically, since it has been considered necessary to conceal the inert nature of a placebo application. Interestingly, the results of recently published small, randomized trials suggest that patients can experience symptom relief after taking pills that they know lack any medication. In particular, these so-called open-label placebos (OLP) improved strongly fluctuating and individually distressing complaints such as...
Source: Der Nervenarzt - July 19, 2020 Category: Neurology Authors: Nestoriuc Y, Kleine-Borgmann J Tags: Nervenarzt Source Type: research

[Electroconvulsive therapy in pregnancy: case report and interdisciplinary treatment suggestions].
CONCLUSION: This case report shows the potentially high effectiveness and safe administration of ECT in pregnancy for both mother and fetus. The undesired adverse events associated with ECT described in the literature are largely qualitatively congruent with the risks of severe psychotic disorders in pregnancy per se. For a better risk-benefit analysis, larger case control studies would be desirable. Under the premise of a thorough evaluation of the indications, good interdisciplinary coordination and consideration of the specific practical requirements, ECT is a useful therapeutic option in pregnancy. PMID:...
Source: Der Nervenarzt - July 16, 2020 Category: Neurology Authors: Zilles-Wegner D, Trost S, Walliser K, Saager L, Horn S, Ernst M Tags: Nervenarzt Source Type: research

[Compulsory medication of people with mental disorders in the penal system : The situation in Germany and recommendations for clinical practice].
CONCLUSIONS: In Germany, there is no legally regulated health-care solution for people with mental disorders in custody in accordance with the laws on the mentally ill of the German federal states (Psychisch-Kranken-Gesetze). Therefore, in the case of serious mental disorders, imprisoned patients cannot be regularly provided with inpatient psychiatric care. As a result, compulsory medication within the correctional system must be considered if the course of the mental disorder is unfavorable. Compulsory medication in the German prison system has a special position compared with compulsory medication in psychiatri...
Source: Der Nervenarzt - July 16, 2020 Category: Neurology Authors: Fuß J, Marquardt I, Briken P, Konrad N Tags: Nervenarzt Source Type: research

[Causes, spectrum, and treatment of the diabetic neuropathy].
CONCLUSION: The diabetic neuropathy is frequent and causes severe complications. A good understanding of the underlying pathophysiology can contribute to the development of novel treatment strategies in the future. PMID: 32647958 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - July 8, 2020 Category: Neurology Authors: Dohrn MF, Winter N, Dafotakis M Tags: Nervenarzt Source Type: research

[Placebo effects in pain therapy].
Abstract In the past few decades, research on pain and placebo analgesia has gained importance both scientifically and clinically. In this article, the current findings and focus of research as well as the significance of placebo research for assessing the effectiveness of pain medication are illustrated. The underlying mechanisms of placebo analgesia not only have implications for theoretical models but also offer clinically relevant guidelines for everyday interventions in pain treatment. However, many placebo phenomena are not fully understood and have to be investigated further in order to exploit the full pot...
Source: Der Nervenarzt - July 7, 2020 Category: Neurology Authors: Klinger R, Schwartz M, Bingel U Tags: Nervenarzt Source Type: research

[The learned placebo response in the immune system].
emann L Abstract The learned placebo response of the immune system is based on the mutual interaction between the brain and the immune system; both systems continually exchange information via humoral and neural communication pathways. This communication network enables the modification, i.e. suppression or stimulation, of peripheral immune functions by classical or Pavlov's conditioning. The present article provides an overview of the results of recent experimental animal studies, which also document the potential clinical relevance of learned immune responses. Learned immunological responses mediated by classica...
Source: Der Nervenarzt - July 7, 2020 Category: Neurology Authors: Hörbelt T, Hetze S, Schedlowski M, Lückemann L Tags: Nervenarzt Source Type: research

[The effect of medical and psychotherapeutic treatment models for schizophrenia on stigma and recovery expectations].
CONCLUSION: There appear to be no negative side effects of (biogenetic) models when presented in a context emphasizing recovery. Moreover, medication and CBT treatment information showed additive positive effects on the rating of treatment strategies. A combined treatment model integrating various evidence-based methods appears to be most useful in clinical practice. PMID: 32642947 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - July 7, 2020 Category: Neurology Authors: Schlier B, Kubera FR, Lincoln TM Tags: Nervenarzt Source Type: research

[Importance of electroconvulsive therapy (ECT) in forensic psychiatry].
CONCLUSION: The use of ECT in German forensic psychiatry is currently very limited. It is striking that the number of applied ECT treatments is eight times lower in comparison to the frequency of indications. Nevertheless, approximately two thirds of the forensic hospitals stated a medium or high need for ECT, which seems to suggest a shortage of ECT in the treatment of forensic psychiatry patients. PMID: 32642948 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - July 7, 2020 Category: Neurology Authors: Besse M, Schomburg AK, Simon A, Hesse D, Müller J, Zilles-Wegner D Tags: Nervenarzt Source Type: research

[Proteinase  3 (cANCA)-associated ulcerative colitis with possible inflammatory leukoencephalopathic CNS involvement].
[Proteinase 3 (cANCA)-associated ulcerative colitis with possible inflammatory leukoencephalopathic CNS involvement]. Nervenarzt. 2020 Jul 08;: Authors: Pompsch M, Veltkamp C, Veltkamp R, Weber R PMID: 32642949 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - July 7, 2020 Category: Neurology Authors: Pompsch M, Veltkamp C, Veltkamp R, Weber R Tags: Nervenarzt Source Type: research

[Placebos and placeboids in clinical practice: conceptual and ethical considerations].
t B Abstract Reflecting on results of recent placebo research, this article analyzes relevant key concepts and ethical positions. "Placeboids" and possibly open-label placebo treatments should replace any deceptive use of sham medication. Their use should give rise to a critical consideration of the modern patient-physician relationship. PMID: 32617632 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - July 1, 2020 Category: Neurology Authors: Schöne-Seifert B Tags: Nervenarzt Source Type: research

[The role of placebo and nocebo mechanisms in depressive diseases and their treatment].
CONCLUSION: The success of treatment in the use of antidepressants can be increased and the probability of side effects can be reduced by the effective use of placebo mechanisms and reduction of nocebo effects. The results emphasize the influence of clinician-patient interactions, the role of the treatment context and previous experiences with other treatments of the patient. Simultaneously, the results of this research field stimulate a new understanding of mental disorders, in particular depression and also provide points of reference for optimization of psychotherapeutic treatment. PMID: 32607602 [PubMed - as suppl...
Source: Der Nervenarzt - June 29, 2020 Category: Neurology Authors: Rief W Tags: Nervenarzt Source Type: research

[Quality psychiatry and destigmatization : Can quality psychiatry and psychotherapy contribute to destigmatization of mental illnesses?]
CONCLUSION: The components of quality psychiatry that can contribute to the destigmatization of persons with mental illnesses include the implementation of regularly updated evidence-based treatment guidelines, the individualization of psychiatric treatment (precision psychiatry) and the application of quality indicators within the framework of comprehensive quality management. The postulated relationships must be empirically verified, further analyzed and communicated to the public to be made systematically useful for the destigmatization of mental illnesses. PMID: 32607603 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - June 29, 2020 Category: Neurology Authors: Gaebel W, Stricker J Tags: Nervenarzt Source Type: research

[Rolf Hassler: from leucotomy to stereotaxy].
Abstract Rolf Hassler is one of the most renowned German specialists in psychiatry, neurology and neuroanatomy. Hassler's career exemplifies medicine as scientific endeavor. Relaying on an expertise in neuroanatomy gained at Oscar and Cecile Vogt's Kaiser Wilhelm Institute, especially regarding the structure of the thalamus, Hassler enabled Freiburg University's neurosurgery clinic the invention of stereotactic "stepped leucotomy" and established thalamotomy internationally in a leading way. While directing the Neuroanatomical/Neurobiological department of the Max Planck Institute for Brain Research from...
Source: Der Nervenarzt - June 15, 2020 Category: Neurology Authors: Rzesnitzek L Tags: Nervenarzt Source Type: research

[New insights into diagnostics and therapy of personality disorders-Changes in ICD-11].
Abstract Personality disorders (PD) occur frequently and show high remission rates in the long term, while psychosocial recovery remains unsuccessful in a substantial proportion of cases. In ICD-11 the traditional view that PDs have a high stability is abandoned. Instead, the minimum duration is 2 years. The diagnostic process differentiates between three degrees of severity (mild, moderate, severe) and five prominent personality trait domains. Optionally, a borderline qualifying factor can be additionally codified. There is sufficient empirical evidence only for the treatment of borderline PD (BPD). Disorder...
Source: Der Nervenarzt - June 14, 2020 Category: Neurology Authors: Jeung-Maarse H, Herpertz SC Tags: Nervenarzt Source Type: research

[The introduction of antipsychotics in the neurological psychiatric hospital of the University of Leipzig and their effects on other forms of therapy, the length of stay and transferrals].
CONCLUSION: Evidence of facilitation of mental rehabilitation through the use of antipsychotics cannot be directly confirmed; however, it appears that the administration beyond a time-limited treatment has contributed to this development and also to the establishment of outpatient facilities. Thus, both a watershed in the psychiatric treatment and a change for the patients themselves could be identified. PMID: 32542433 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - June 14, 2020 Category: Neurology Authors: Oeser C, Steinberg H Tags: Nervenarzt Source Type: research

[Ocrelizumab for treatment of multiple sclerosis].
Abstract Ocrelizumab is a monoclonal antibody directed against the differentiation antigen CD20, which leads to an effective long-term depletion of lymphocytes, in particular B cells. Recently published phase 3 studies confirmed that ocrelizumab is effective in the treatment of both relapsing multiple sclerosis (RMS) and primary progressive multiple sclerosis (PPMS). Based on these results, ocrelizumab was the first drug to be approved for primary chronic progressive MS. To place this therapeutic breakthrough in the context of the current MS therapeutic landscape, it is worthwhile taking a look...
Source: Der Nervenarzt - June 9, 2020 Category: Neurology Authors: Graf J, Albrecht P, Goebels N, Aktas O, Hartung HP Tags: Nervenarzt Source Type: research

[Therese Neumann between passion experience and trauma sequelae disorder-an informative example for the present?]
PMID: 32504249 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - June 4, 2020 Category: Neurology Authors: Braun B, Demling J, Loew T Tags: Nervenarzt Source Type: research

[Neuropsychological disorders of memory].
This article provides an introduction to the neuropsychology of human memory. The terms short-term memory, working memory, episodic memory, semantic and procedural memory are defined and the anatomical correlates of these various memory systems are presented. Additionally, a brief introduction to the methods for neuropsychological research on human memory is given together with advice on the neuropsychological diagnostics and therapy. PMID: 32504250 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - June 4, 2020 Category: Neurology Authors: Bormann T, Weiller C Tags: Nervenarzt Source Type: research

[Psychopharmacotherapy during the COVID-19 pandemic].
Abstract In view of the current coronavirus disease 2019 (COVID-19) pandemic, patient care, including that of psychiatric patients, is facing unprecedented challenges. Treatment strategies for mental illness include psychotherapy and psychopharmacological interventions. The latter are associated with a multitude of adverse drug reactions (ADR); however, they may currently represent the preferred treatment due to restrictions regarding patient care (i.e. social distancing). Direct contact to patients may have to be reduced in favor of telephone calls or video conferences, so that new techniques in diagnosing a...
Source: Der Nervenarzt - June 1, 2020 Category: Neurology Authors: Seifert J, Heck J, Eckermann G, Singer M, Bleich S, Grohmann R, Toto S Tags: Nervenarzt Source Type: research

[Risk factors for risky cannabis use : A  retrospective cohort study of 7671 cannabis users].
CONCLUSION: Potentially influenceable risk factors for risky cannabis use are relationship quality in the parental home and early onset of cannabis use. PMID: 32488414 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - June 1, 2020 Category: Neurology Authors: Seidel AK, Morgenstern M, Hanewinkel R Tags: Nervenarzt Source Type: research

[Confusion, grand mal series and lactic acidosis in a  46-year-old woman].
[Confusion, grand mal series and lactic acidosis in a 46-year-old woman]. Nervenarzt. 2020 Jun 02;: Authors: Friedrich M, Herrmann R, Klötzsch C PMID: 32488415 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - June 1, 2020 Category: Neurology Authors: Friedrich M, Herrmann R, Klötzsch C Tags: Nervenarzt Source Type: research

[Effectiveness of short-term therapy: the concept of the crisis day clinic].
PMID: 32488416 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - June 1, 2020 Category: Neurology Authors: Illner SC, Ueberberg B, Assion HJ Tags: Nervenarzt Source Type: research

[Social milieu: A  relevant concept for a better understanding of stigma and help-seeking?]
CONCLUSION: The concept of the social milieu constitutes a potentially important and so far barely used intersection between sociology and medicine. Against the backdrop of rising public polarization and social inequality, the concept could contribute to achieving a better understanding of the stigma of mental illness. It appears to be of relevance in a number of ways for secondary and tertiary preventive considerations regarding the treatment gap in mental healthcare. PMID: 32458012 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - May 25, 2020 Category: Neurology Authors: Speerforck S, Schomerus G Tags: Nervenarzt Source Type: research

[Chronic pain syndromes and other persistent functional somatic symptoms].
Abstract Somatic symptoms including pain are everyday human experiences. They usually result from a complex interaction of stimuli, interpretation and reaction, and are not necessarily proportional to structural damage. Persistent functional somatic symptoms can be associated with a significant impairment of quality of life and functioning, even without mental or somatic comorbidity. Dysfunctional experiences, expectancies and behavior, not only by patients but also by physicians, can increase the risk of chronification. From the outset, management should be graded with respect to the severity and biopsychoso...
Source: Der Nervenarzt - May 19, 2020 Category: Neurology Authors: Roenneberg C, Henningsen P, Hausteiner-Wiehle C Tags: Nervenarzt Source Type: research

[Dystextia as a  sign of acute stroke].
[Dystextia as a sign of acute stroke]. Nervenarzt. 2020 May 19;: Authors: Hörmanseder B, Heitzeneder T, Hödl G, Topakian R PMID: 32430551 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - May 18, 2020 Category: Neurology Authors: Hörmanseder B, Heitzeneder T, Hödl G, Topakian R Tags: Nervenarzt Source Type: research

[LATE: not every dementia is Alzheimer's disease-Discussion of a  new disease entity based on a case example : Current status of limbic-predominant age-related TDP-43 encephalopathy (LATE)].
This article presents the current state of the discussion on LATE and illustrates the concept and the clinical considerations with a case study. PMID: 32409844 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - May 13, 2020 Category: Neurology Authors: Görß D, Kilimann I, Dyrba M, Nitsch S, Krause B, Teipel S Tags: Nervenarzt Source Type: research

[Therese Neumann between spirituality and religious pathology-an illuminating paradigm for the present?]
PMID: 32409845 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - May 13, 2020 Category: Neurology Authors: Seidl O Tags: Nervenarzt Source Type: research

[Info-Telefon Depression-An exploratory analysis of data from callers to a  German information hotline for depression].
[Info-Telefon Depression-An exploratory analysis of data from callers to a German information hotline for depression]. Nervenarzt. 2020 May 13;: Authors: Görges F, Gravert C, Rummel-Kluge C, Hegerl U PMID: 32405691 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - May 12, 2020 Category: Neurology Authors: Görges F, Gravert C, Rummel-Kluge C, Hegerl U Tags: Nervenarzt Source Type: research

[Nonpharmacological treatment options for attention deficit hyperactivity disorder in adulthood: an update].
Abstract Attention deficit hyperactivity disorder (ADHD) in adulthood is a frequent disorder with a prevalence of 2.5%, which can successfully be treated by pharmacotherapy in 50-70% of cases, depending on the response criteria. Therefore, besides medication nonpharmacological interventions are an important component of the treatment. The essential nonpharmacological interventions are presented and described with respect to the evidence for treatment. According to the S3 guidelines an extensive psychoeducation (PE) functions as the basis of the treatment. If there is still a need for treatment after...
Source: Der Nervenarzt - May 11, 2020 Category: Neurology Authors: Lux S, Rosen H, Aslan B, Philipsen A Tags: Nervenarzt Source Type: research

[The prevalence of people with dementia in Germany-A  nationwide analysis at the district level].
[The prevalence of people with dementia in Germany-A nationwide analysis at the district level]. Nervenarzt. 2020 May 12;: Authors: Thyrian JR, Boekholt M, Hoffmann W, Leiz M, Monsees J, Schmachtenberg T, Schumacher-Schönert F, Stentzel U PMID: 32399609 [PubMed - as supplied by publisher] (Source: Der Nervenarzt)
Source: Der Nervenarzt - May 11, 2020 Category: Neurology Authors: Thyrian JR, Boekholt M, Hoffmann W, Leiz M, Monsees J, Schmachtenberg T, Schumacher-Schönert F, Stentzel U Tags: Nervenarzt Source Type: research

[Recommendations for gene therapy of spinal muscular atrophy with onasemnogene abeparvovec-AVXS-101 : Consensus paper of the German representatives of the Society for Pediatric Neurology (GNP) and the German treatment centers with collaboration of the medical scientific advisory board of the German Society for Muscular Diseases (DGM)].
CONCLUSION: Gene replacement therapy with onasemnogene abeparvovec has the potential to significantly influence the course of SMA. Long-term data on sustainability of effects and possible adverse effects of gene replacement therapy are not yet available. The application of this innovative therapy must be carried out in specialized and appropriately qualified treatment centers under strict safety conditions. This article makes suggestions for the necessary framework conditions and gives recommendations for a systematic pretreatment and posttreatment assessment schedule under gene therapy. The effectiveness and safety o...
Source: Der Nervenarzt - May 10, 2020 Category: Neurology Authors: Ziegler A, Wilichowski E, Schara U, Hahn A, Müller-Felber W, Johannsen J, von der Hagen M, von Moers A, Stoltenburg C, Saffari A, Walter MC, Husain RA, Pechmann A, Köhler C, Horber V, Schwartz O, Kirschner J Tags: Nervenarzt Source Type: research