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Gut Microbiota Exchange in Domestic Animals and Rural-urban People Axis
In this study, we examined the gut microbiota in various animals, including dogs, cats, dairy cows, sheep, chickens, horses, and people who live in urban and rural areas. Based on the review of various studies, it has been determined that the population of microbiota in animals and humans is different, and various factors such as the environment, nutrition, and contact with animals can affect the microbiota of people living in urban and rural areas.PMID:37877143 | DOI:10.2174/0113892010261535230920062107 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - October 25, 2023 Category: Biotechnology Authors: Javad Nezhadi Mohammad Ahangarzadeh Rezaee Mahdi Asghari Ozma Khudaverdi Ganbarov Hossein Samadi Kafil Source Type: research

Probiotics Show Promise as a Novel Natural Treatment for Neurological Disorders
Curr Pharm Biotechnol. 2023 Oct 18. doi: 10.2174/0113892010261604230919170143. Online ahead of print.ABSTRACTProbiotics are beneficial microorganisms shown to improve human health when consumed regularly and in sufficient quantities. Numerous health benefits can be attained by possessing important metabolites with nutritional and medicinal qualities. It has been shown through scientific research that these living microbial consortiums can influence a variety of mental health outcomes, including but not limited to anxiety, depression, cognitive processes, stress responses, and behavioral patterns. Selected strains of bacter...
Source: Current Pharmaceutical Biotechnology - October 25, 2023 Category: Biotechnology Authors: Preeti Jha Neha Dangi Shikha Sharma Source Type: research

Effect of Nigella sativa Intake on Oxidative Stress and Inflammation in Patients with Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-analysis of Randomized Controlled Trials
CONCLUSION: Our results showed that THE consumption of N. sativa could be associated with improved oxidative stress and inflammation in patients with metabolic syndrome and related disorders.PMID:37859312 | DOI:10.2174/0113892010266109230928000134 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - October 20, 2023 Category: Biotechnology Authors: Hossein Hosseini Farideh Ghavidel Mahdieh Aliyari Seyed Isaac Hashemy Tannaz Jamialahmadi Amirhossein Sahebkar Source Type: research

A Glance on Nanovaccine: A Potential Approach for Disease Prevention
Curr Pharm Biotechnol. 2023 Oct 11. doi: 10.2174/0113892010254221231006100659. Online ahead of print.ABSTRACTThere are several vaccines available for preventing various bacterial and viral infections, but still, there are many challenges that require the development of noninvasive, more efficient, and active vaccines. The advancement in biotechnological tools has provided safer antigens, such as nucleic acids, proteins etc., but due to their lower immunogenic property, adjuvants of stronger immune response are required. Nanovaccines are effective vaccines when compared with conventional vaccines as they can induce both Hum...
Source: Current Pharmaceutical Biotechnology - October 20, 2023 Category: Biotechnology Authors: Akash Garg Himansu Chopra Talever Singh Ramkumar Chaudhary Rutvi Agrawal Abhishek Tankara Source Type: research

Exploring the Theranostic Applications and Prospects of Nanobubbles
Curr Pharm Biotechnol. 2023 Oct 12. doi: 10.2174/0113892010248189231010085827. Online ahead of print.ABSTRACTAnticancer medications as well as additional therapeutic compounds, have poor clinical effectiveness due to their diverse distribution, non-selectivity for malignant cells, and undesirable off-target side effects. As a result, ultrasound-based targeted delivery of therapeutic compounds carried in sophisticated nanocarriers has grown in favor of cancer therapy and control. Nanobubbles are nanoscale bubbles that exhibit unique physiochemical properties in both their inner core and outer shell. Manufacturing nanobubble...
Source: Current Pharmaceutical Biotechnology - October 20, 2023 Category: Biotechnology Authors: Rahul Shah Niraj Phatak Ashok Choudhary Sakshi Gadewar Ajaz Uddin Sankha Bhattacharya Source Type: research

Folate-chitosan Coated Quercetin Liposomes for Targeted Cancer Therapy
CONCLUSION: FA-CS-QUE-LP exhibited a significant inhibitory effect on HepG2 cells, influenced the pharmacokinetics of quercetin in mice, and demonstrated a certain inhibitory effect on S180 tumor-bearing mice, thus offering novel avenues for cancer treatment.PMID:37861012 | DOI:10.2174/0113892010264479231006045014 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - October 20, 2023 Category: Biotechnology Authors: Chunhui Chang Deen Han Yuying Ji Donghong Li Zhiling Xu Jiahao Li Shengnan Huang Xiali Zhu Yongyan Jia Mengyan -Wang Source Type: research

Sida cordifolia L.: Ethnobotany, Phytochemistry, Phytonanotechnology, and Commercial Application
CONCLUSION: Several in-vitro and in-vivo studies validated the usage of S. cordifolia as antiinflammatory, antibacterial, antifungal, antiprotozoal, anthelmintic, anticancer, antiulcer, cardioprotective, hypoglycemic, etc. agent. Few patents are also related to S. cordifolia, and more research work needs to be carried out for its potential granted to use as an antiviral agent and other new drug discovery molecules.PMID:37861013 | DOI:10.2174/0113892010262937230919100024 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - October 20, 2023 Category: Biotechnology Authors: Sachin Kumar Sandeep Kumar Vineet Kumar Vishnoi Pradeep Kumar Dinesh Kumar Maheshwari Source Type: research

BAO-Ag-NPs as Promising Suppressor of ET-1/ICAM-1/VCAM-1 Signaling Pathway in ISO-induced AMI in Rats
CONCLUSION: BAO-Ag-NPs protect against AMI in vivo by regulating inflammation, excessive autophagy, and oxidative stress, as well as lowering apoptosis via suppression of the ET-1, ICAM-1, and VCAM-1 signaling pathways.PMID:37861014 | DOI:10.2174/0113892010256434231010062233 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - October 20, 2023 Category: Biotechnology Authors: Hayam Ateyya Mohammed Hussein Ahmed Moro Ebtsam Abdel-Wahab Amr A El-Ella Yasser Mosaa Zahraa Nassar Source Type: research

Review on Nutritional Potential of Underutilized Millets as a Miracle Grain
Curr Pharm Biotechnol. 2023 Oct 9. doi: 10.2174/0113892010248721230921093208. Online ahead of print.ABSTRACTThe current situation, which includes changes in eating habits, an increasing population, and the unrestricted use of natural resources, has resulted in a lack of resources that could be used to provide nourishing food to everyone. Natural plant resources are quickly being depleted, so it is necessary to consider new alternatives. In addition to the staple grains of rice and wheat, many other crops are being consumed that need to be utilized to their full potential and have the potential to replace the staple crops. ...
Source: Current Pharmaceutical Biotechnology - October 20, 2023 Category: Biotechnology Authors: Sonia Singh Himanshu Sharma Raghavan Ramankutty Sarada Ramaswamy Source Type: research