Nanotechnology Integrated Innovative Drug Delivery and Therapy for Cancer
Curr Pharm Biotechnol. 2024 Apr 22. doi: 10.2174/0113892010279483240417050548. Online ahead of print.ABSTRACTCancer remains a significant global health challenge, necessitating innovative approaches to enhance the efficacy and specificity of therapeutic interventions while minimizing adverse effects on healthy tissues. Nanotechnology has emerged as a promising avenue in cancer treatment, offering novel strategies for targeted drug delivery. Nanoparticles, liposomes, and polymer-based systems have played pivotal roles in revolutionizing cancer therapy. Nanotechnology possesses unique physicochemical properties, enabling eff...
Source: Current Pharmaceutical Biotechnology - May 8, 2024 Category: Biotechnology Authors: Romulo R Macadangdang Rutvi Agrawal Bharat Bhushan Akash Garg Kuldeep Singh Shivendra Kumar Atul Kumar Source Type: research

Fisetin from Dietary Supplement to a Drug Candidate: An Assessment of Potential - A Review
Curr Pharm Biotechnol. 2024 Apr 22. doi: 10.2174/0113892010304479240415074928. Online ahead of print.ABSTRACTFisetin is a bioactive compound found in numerous fruits and vegetables, including strawberries, apples, grapes, persimmon, cucumber, onion, etc. The compound is also wellknown for its neurotrophic, anti-inflammatory, anti-carcinogenic, anti-diabetic, and other healthpromoting properties. Although there is increasing agreement that it has therapeutic properties, its poor water solubility, high lipophilicity, and lower oral bioavailability make it difficult to use clinically. Extensive research has attempted to overc...
Source: Current Pharmaceutical Biotechnology - May 8, 2024 Category: Biotechnology Authors: Mohd Aamir Mirza Santwana Padhi Sradhanjali Mohapatra Syed Mahmood Zeenat Iqbal Source Type: research

Nanotechnology-Powered Meningitis Therapies: Lipid Nanoparticles Lead the Way
Curr Pharm Biotechnol. 2024 May 3. doi: 10.2174/0113892010303028240429073144. Online ahead of print.ABSTRACTThe meninges serve as a protective layer, and the fluid around the brain and spinal cord can become inflamed, known as meningitis. Lipid-based pharmaceutical formulations, by their high lipophilicity, can negotiate the Blood-Brain Barrier (BBB). The current mode of treatment of meningitis is mainly through antibiotics, which, at best, is partially effective. The success of antibiotic therapy depends on several factors, for example, the difficulty of reaching the infection site, maintaining proper concentrations of th...
Source: Current Pharmaceutical Biotechnology - May 6, 2024 Category: Biotechnology Authors: Dipanjan Karati Swarupananda Mukherjee Susmita Paul Suchana Das Bhupendra Prajapati Ravish J Patel Sajal Kumar Jha Source Type: research

Nanotechnology-Powered Meningitis Therapies: Lipid Nanoparticles Lead the Way
Curr Pharm Biotechnol. 2024 May 3. doi: 10.2174/0113892010303028240429073144. Online ahead of print.ABSTRACTThe meninges serve as a protective layer, and the fluid around the brain and spinal cord can become inflamed, known as meningitis. Lipid-based pharmaceutical formulations, by their high lipophilicity, can negotiate the Blood-Brain Barrier (BBB). The current mode of treatment of meningitis is mainly through antibiotics, which, at best, is partially effective. The success of antibiotic therapy depends on several factors, for example, the difficulty of reaching the infection site, maintaining proper concentrations of th...
Source: Current Pharmaceutical Biotechnology - May 6, 2024 Category: Biotechnology Authors: Dipanjan Karati Swarupananda Mukherjee Susmita Paul Suchana Das Bhupendra Prajapati Ravish J Patel Sajal Kumar Jha Source Type: research

Optimization of Phloretin-loaded Nanospanlastics for Targeting of FAS/SREBP1c/AMPK/ OB-Rb Signaling Pathway in HFD-induced Obesity
CONCLUSIONS: Administration of PTN-NSLs significantly attenuated the levels of glycemic, oxidative stress, and inflammatory biomarkers. The biochemical and PCR findings are aided by histological investigations. Also, the present findings imply that PTN-NSLs might be a promising pharmacological tool for the treatment of obesity-related diseases.PMID:38698746 | DOI:10.2174/0113892010278684240105115516 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - May 3, 2024 Category: Biotechnology Authors: Mohamed Alamir Mohammed Abdalla Hussein Heba M Aboud Mohamed H Khedr Mohamed I Zanaty Source Type: research

Optimization of Phloretin-loaded Nanospanlastics for Targeting of FAS/SREBP1c/AMPK/ OB-Rb Signaling Pathway in HFD-induced Obesity
CONCLUSIONS: Administration of PTN-NSLs significantly attenuated the levels of glycemic, oxidative stress, and inflammatory biomarkers. The biochemical and PCR findings are aided by histological investigations. Also, the present findings imply that PTN-NSLs might be a promising pharmacological tool for the treatment of obesity-related diseases.PMID:38698746 | DOI:10.2174/0113892010278684240105115516 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - May 3, 2024 Category: Biotechnology Authors: Mohamed Alamir Mohammed Abdalla Hussein Heba M Aboud Mohamed H Khedr Mohamed I Zanaty Source Type: research

Optimization of Phloretin-loaded Nanospanlastics for Targeting of FAS/SREBP1c/AMPK/ OB-Rb Signaling Pathway in HFD-induced Obesity
CONCLUSIONS: Administration of PTN-NSLs significantly attenuated the levels of glycemic, oxidative stress, and inflammatory biomarkers. The biochemical and PCR findings are aided by histological investigations. Also, the present findings imply that PTN-NSLs might be a promising pharmacological tool for the treatment of obesity-related diseases.PMID:38698746 | DOI:10.2174/0113892010278684240105115516 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - May 3, 2024 Category: Biotechnology Authors: Mohamed Alamir Mohammed Abdalla Hussein Heba M Aboud Mohamed H Khedr Mohamed I Zanaty Source Type: research

DHA and Cancer: The Uncharted Territory of Nutritional Oncology
Curr Pharm Biotechnol. 2024 Apr 26. doi: 10.2174/0113892010305256240422110943. Online ahead of print.NO ABSTRACTPMID:38676504 | DOI:10.2174/0113892010305256240422110943 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - April 27, 2024 Category: Biotechnology Authors: Devank Shekho Abhishek Chauhan Ritika Mishra Ankit Awasthi Source Type: research

DHA and Cancer: The Uncharted Territory of Nutritional Oncology
Curr Pharm Biotechnol. 2024 Apr 26. doi: 10.2174/0113892010305256240422110943. Online ahead of print.NO ABSTRACTPMID:38676504 | DOI:10.2174/0113892010305256240422110943 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - April 27, 2024 Category: Biotechnology Authors: Devank Shekho Abhishek Chauhan Ritika Mishra Ankit Awasthi Source Type: research

DHA and Cancer: The Uncharted Territory of Nutritional Oncology
Curr Pharm Biotechnol. 2024 Apr 26. doi: 10.2174/0113892010305256240422110943. Online ahead of print.NO ABSTRACTPMID:38676504 | DOI:10.2174/0113892010305256240422110943 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - April 27, 2024 Category: Biotechnology Authors: Devank Shekho Abhishek Chauhan Ritika Mishra Ankit Awasthi Source Type: research

DHA and Cancer: The Uncharted Territory of Nutritional Oncology
Curr Pharm Biotechnol. 2024 Apr 26. doi: 10.2174/0113892010305256240422110943. Online ahead of print.NO ABSTRACTPMID:38676504 | DOI:10.2174/0113892010305256240422110943 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - April 27, 2024 Category: Biotechnology Authors: Devank Shekho Abhishek Chauhan Ritika Mishra Ankit Awasthi Source Type: research

Quantum Dots in Cancer Theranostics: A Thorough Review of Recent Advancements in Bioimaging, Tracking, and Therapy across Various Cancer Types
This study provides an overview of the most recent developments in applying QDs for diagnostic and therapeutic purposes, also known as theranostics. It emphasizes specifically the use of QDs in cancer therapy.PMID:38644717 | DOI:10.2174/0113892010294163240407153842 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - April 22, 2024 Category: Biotechnology Authors: Amir Matini Seyed Morteza Naghib M R Mozafari Source Type: research

Quantum Dots in Cancer Theranostics: A Thorough Review of Recent Advancements in Bioimaging, Tracking, and Therapy across Various Cancer Types
This study provides an overview of the most recent developments in applying QDs for diagnostic and therapeutic purposes, also known as theranostics. It emphasizes specifically the use of QDs in cancer therapy.PMID:38644717 | DOI:10.2174/0113892010294163240407153842 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - April 22, 2024 Category: Biotechnology Authors: Amir Matini Seyed Morteza Naghib M R Mozafari Source Type: research

Quantum Dots in Cancer Theranostics: A Thorough Review of Recent Advancements in Bioimaging, Tracking, and Therapy across Various Cancer Types
This study provides an overview of the most recent developments in applying QDs for diagnostic and therapeutic purposes, also known as theranostics. It emphasizes specifically the use of QDs in cancer therapy.PMID:38644717 | DOI:10.2174/0113892010294163240407153842 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - April 22, 2024 Category: Biotechnology Authors: Amir Matini Seyed Morteza Naghib M R Mozafari Source Type: research

Quantum Dots in Cancer Theranostics: A Thorough Review of Recent Advancements in Bioimaging, Tracking, and Therapy across Various Cancer Types
This study provides an overview of the most recent developments in applying QDs for diagnostic and therapeutic purposes, also known as theranostics. It emphasizes specifically the use of QDs in cancer therapy.PMID:38644717 | DOI:10.2174/0113892010294163240407153842 (Source: Current Pharmaceutical Biotechnology)
Source: Current Pharmaceutical Biotechnology - April 22, 2024 Category: Biotechnology Authors: Amir Matini Seyed Morteza Naghib M R Mozafari Source Type: research