AALAS Position Statement on the Humane Care and Use of Laboratory Animals
Comp Med. 2023 Aug 27;73(4):329.ABSTRACTThe American Association for Laboratory Animal Science endorses the United States Government "Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training" and requires that all papers published in Comparative Medicine report research conducted in conformance with these principles. Research for papers submitted from outside the United States must be in conformance with the guidelines of that country's government. The Editor reserves the right to reject papers reporting results of research not adhering to these principles.PMID:37885100 (Source:...
Source: Comparative Medicine - October 27, 2023 Category: Zoology Source Type: research
AALAS Position Statement on the Humane Care and Use of Laboratory Animals
Comp Med. 2023 Aug 27;73(4):329.ABSTRACTThe American Association for Laboratory Animal Science endorses the United States Government "Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training" and requires that all papers published in Comparative Medicine report research conducted in conformance with these principles. Research for papers submitted from outside the United States must be in conformance with the guidelines of that country's government. The Editor reserves the right to reject papers reporting results of research not adhering to these principles.PMID:37885100 (Source:...
Source: Comparative Medicine - October 27, 2023 Category: Zoology Source Type: research
AALAS Position Statement on the Humane Care and Use of Laboratory Animals
Comp Med. 2023 Aug 27;73(4):329.ABSTRACTThe American Association for Laboratory Animal Science endorses the United States Government "Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training" and requires that all papers published in Comparative Medicine report research conducted in conformance with these principles. Research for papers submitted from outside the United States must be in conformance with the guidelines of that country's government. The Editor reserves the right to reject papers reporting results of research not adhering to these principles.PMID:37885100 (Source:...
Source: Comparative Medicine - October 27, 2023 Category: Zoology Source Type: research
AALAS Position Statement on the Humane Care and Use of Laboratory Animals
Comp Med. 2023 Aug 27;73(4):329.ABSTRACTThe American Association for Laboratory Animal Science endorses the United States Government "Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training" and requires that all papers published in Comparative Medicine report research conducted in conformance with these principles. Research for papers submitted from outside the United States must be in conformance with the guidelines of that country's government. The Editor reserves the right to reject papers reporting results of research not adhering to these principles.PMID:37885100 (Source:...
Source: Comparative Medicine - October 27, 2023 Category: Zoology Source Type: research
AALAS Position Statement on the Humane Care and Use of Laboratory Animals
Comp Med. 2023 Aug 27;73(4):329.ABSTRACTThe American Association for Laboratory Animal Science endorses the United States Government "Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training" and requires that all papers published in Comparative Medicine report research conducted in conformance with these principles. Research for papers submitted from outside the United States must be in conformance with the guidelines of that country's government. The Editor reserves the right to reject papers reporting results of research not adhering to these principles.PMID:37885100 (Source:...
Source: Comparative Medicine - October 27, 2023 Category: Zoology Source Type: research
AALAS Position Statement on the Humane Care and Use of Laboratory Animals
Comp Med. 2023 Aug 27;73(4):329.ABSTRACTThe American Association for Laboratory Animal Science endorses the United States Government "Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training" and requires that all papers published in Comparative Medicine report research conducted in conformance with these principles. Research for papers submitted from outside the United States must be in conformance with the guidelines of that country's government. The Editor reserves the right to reject papers reporting results of research not adhering to these principles.PMID:37885100 (Source:...
Source: Comparative Medicine - October 27, 2023 Category: Zoology Source Type: research
AALAS Position Statement on the Humane Care and Use of Laboratory Animals
Comp Med. 2023 Aug 27;73(4):329.ABSTRACTThe American Association for Laboratory Animal Science endorses the United States Government "Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training" and requires that all papers published in Comparative Medicine report research conducted in conformance with these principles. Research for papers submitted from outside the United States must be in conformance with the guidelines of that country's government. The Editor reserves the right to reject papers reporting results of research not adhering to these principles.PMID:37885100 (Source:...
Source: Comparative Medicine - October 27, 2023 Category: Zoology Source Type: research
Cold Agglutinin Disease in a Rhesus Macaque (Macaca mulatta)
In this report, we describe a case of CAD in a previouslyhealthy and experimentally naïve adult Indian rhesus macaque that was housed indoors and presented with blood in theurine. After our observations of hemoglobinuria and anemia led us to suspect CAD, we demonstrated that the macaque'sblood agglutinated at reduced temperatures. We also noticed that the provision of cold foraging treats triggered episodes ofhemoglobinuria. Further investigation revealed that serum from the macaque agglutinated RBCs in vitro with high thermalamplitude (at or below 30 °C) and had an antibody titer of 8 to 32. The serum contained autoanti...
Source: Comparative Medicine - October 23, 2023 Category: Zoology Authors: Cris Kamperschroer Karrie Tartaro Laurie Goodchild Chelsea Menke Ashley Artrip Harshan Pisharath Source Type: research
Assessment of Oral Albendazole and Fumagillin in the Treatment of Pseudoloma neurophilia in Adult Zebrafish
Comp Med. 2023 Oct 23. doi: 10.30802/AALAS-CM-23-000035. Online ahead of print.ABSTRACTPseudoloma neurophilia (Pn), the causative agent of the most commonly reported disease of zebrafish, is a microsporidianparasite that confounds research by inducing behavioral and physiologic changes in zebrafish. Although a treatmentfor P. neurophilia has not been documented in zebrafish, albendazole (ALB) and fumagillin (FUM) have been used to treatmicrosporidian infections of other fish species. To investigate the efficacy of oral ALB and FUM in the treatment of Pn, weperformed a pilot study that demonstrated the safety and palatabili...
Source: Comparative Medicine - October 23, 2023 Category: Zoology Authors: Elizabeth S Lavin Rodman G Getchell Erin K Daugherity Michael L Kent Adam D Frosolone Renata Ivanek Source Type: research
Cold Agglutinin Disease in a Rhesus Macaque (Macaca mulatta)
In this report, we describe a case of CAD in a previouslyhealthy and experimentally naïve adult Indian rhesus macaque that was housed indoors and presented with blood in theurine. After our observations of hemoglobinuria and anemia led us to suspect CAD, we demonstrated that the macaque'sblood agglutinated at reduced temperatures. We also noticed that the provision of cold foraging treats triggered episodes ofhemoglobinuria. Further investigation revealed that serum from the macaque agglutinated RBCs in vitro with high thermalamplitude (at or below 30 °C) and had an antibody titer of 8 to 32. The serum contained autoanti...
Source: Comparative Medicine - October 23, 2023 Category: Zoology Authors: Cris Kamperschroer Karrie Tartaro Laurie Goodchild Chelsea Menke Ashley Artrip Harshan Pisharath Source Type: research
Assessment of Oral Albendazole and Fumagillin in the Treatment of Pseudoloma neurophilia in Adult Zebrafish
Comp Med. 2023 Oct 23. doi: 10.30802/AALAS-CM-23-000035. Online ahead of print.ABSTRACTPseudoloma neurophilia (Pn), the causative agent of the most commonly reported disease of zebrafish, is a microsporidianparasite that confounds research by inducing behavioral and physiologic changes in zebrafish. Although a treatmentfor P. neurophilia has not been documented in zebrafish, albendazole (ALB) and fumagillin (FUM) have been used to treatmicrosporidian infections of other fish species. To investigate the efficacy of oral ALB and FUM in the treatment of Pn, weperformed a pilot study that demonstrated the safety and palatabili...
Source: Comparative Medicine - October 23, 2023 Category: Zoology Authors: Elizabeth S Lavin Rodman G Getchell Erin K Daugherity Michael L Kent Adam D Frosolone Renata Ivanek Source Type: research
Cold Agglutinin Disease in a Rhesus Macaque (Macaca mulatta)
In this report, we describe a case of CAD in a previouslyhealthy and experimentally naïve adult Indian rhesus macaque that was housed indoors and presented with blood in theurine. After our observations of hemoglobinuria and anemia led us to suspect CAD, we demonstrated that the macaque'sblood agglutinated at reduced temperatures. We also noticed that the provision of cold foraging treats triggered episodes ofhemoglobinuria. Further investigation revealed that serum from the macaque agglutinated RBCs in vitro with high thermalamplitude (at or below 30 °C) and had an antibody titer of 8 to 32. The serum contained autoanti...
Source: Comparative Medicine - October 23, 2023 Category: Zoology Authors: Cris Kamperschroer Karrie Tartaro Laurie Goodchild Chelsea Menke Ashley Artrip Harshan Pisharath Source Type: research
Assessment of Oral Albendazole and Fumagillin in the Treatment of Pseudoloma neurophilia in Adult Zebrafish
Comp Med. 2023 Oct 23. doi: 10.30802/AALAS-CM-23-000035. Online ahead of print.ABSTRACTPseudoloma neurophilia (Pn), the causative agent of the most commonly reported disease of zebrafish, is a microsporidianparasite that confounds research by inducing behavioral and physiologic changes in zebrafish. Although a treatmentfor P. neurophilia has not been documented in zebrafish, albendazole (ALB) and fumagillin (FUM) have been used to treatmicrosporidian infections of other fish species. To investigate the efficacy of oral ALB and FUM in the treatment of Pn, weperformed a pilot study that demonstrated the safety and palatabili...
Source: Comparative Medicine - October 23, 2023 Category: Zoology Authors: Elizabeth S Lavin Rodman G Getchell Erin K Daugherity Michael L Kent Adam D Frosolone Renata Ivanek Source Type: research
Evaluation of Selected Markers in Kidneys of Cynomolgus Monkey (Macaca fascicularis) with Induced Diabetes during Renal Ischemia-reperfusion Injury
Comp Med. 2023 Oct 19. doi: 10.30802/AALAS-CM-22-000127. Online ahead of print.ABSTRACTWe previously reported that induced type 1 diabetes mellitus (DM) increases the susceptibility of acute kidney injury inducedby ischemia-reperfusion injury (IRI) in cynomolgus monkeys. In this follow-up study, we compared the expression ofselected markers in the renal tissues of monkeys subjected to bilateral renal IRI with and without diabetes. All tissues wereobtained from the original study. Renal biopsies were obtained before and 24 and 48 h after ischemia and were examinedfor expression of KI-67 (tubular proliferation), Na+/K+ ATPas...
Source: Comparative Medicine - October 20, 2023 Category: Zoology Authors: Tae M Kim Kyo W Lee Hong D Kim Sung O Hong Hye J Cho Je H Yang Sung J Kim Jae B Park Source Type: research
Evaluation of Selected Markers in Kidneys of Cynomolgus Monkey (Macaca fascicularis) with Induced Diabetes during Renal Ischemia-reperfusion Injury
Comp Med. 2023 Oct 19. doi: 10.30802/AALAS-CM-22-000127. Online ahead of print.ABSTRACTWe previously reported that induced type 1 diabetes mellitus (DM) increases the susceptibility of acute kidney injury inducedby ischemia-reperfusion injury (IRI) in cynomolgus monkeys. In this follow-up study, we compared the expression ofselected markers in the renal tissues of monkeys subjected to bilateral renal IRI with and without diabetes. All tissues wereobtained from the original study. Renal biopsies were obtained before and 24 and 48 h after ischemia and were examinedfor expression of KI-67 (tubular proliferation), Na+/K+ ATPas...
Source: Comparative Medicine - October 20, 2023 Category: Zoology Authors: Tae M Kim Kyo W Lee Hong D Kim Sung O Hong Hye J Cho Je H Yang Sung J Kim Jae B Park Source Type: research
