Isolation and Characterization of a Novel Alpha-Hemolytic Streptococcus spp. from the Oral Cavity and Blood of Septicemic Periparturient Immunodeficient Mice
Comp Med. 2023 Sep 11. doi: 10.30802/AALAS-CM-23-000020. Online ahead of print.ABSTRACTMISTRG is an immunodeficient mouse strain that expresses multiple human cytokines that support hematopoietic stem cell maintenance and myelopoiesis. While establishing a breeding colony of MISTRG mice in a dedicated barrier room, 6 cases of death or disease occurred in pregnant or postpartum mice. Clinically, this manifested as hunched posture, dyspnea, and 1 case of emaciation with ataxia. Pathologic analysis of 7 mice revealed multisystemic necrosuppurative inflammation variably affecting the uterus and placenta, joints, meninges, inne...
Source: Comparative Medicine - September 11, 2023 Category: Zoology Authors: Amy Funk Qidong Jia Laura Janke Ashley Crawford Amy Iverson Jason Rosch Joseph Emmons Chandra Savage Heather Glasgow Randall Hayden Elisa Margolis Harshan Pisharath Source Type: research
Polyomavirus-associated Disseminated T-cell Lymphoma in a Colony of Zebra Finches (Taeniopygia guttata)
Comp Med. 2023 Sep 11. doi: 10.30802/AALAS-CM-23-000011. Online ahead of print.ABSTRACTFour zebra finches in a closed research colony presented with variable clinical signs, including masses, skin lesions,shivering, and/or ruffled feathers. These birds were not responsive to treatment efforts; 3 died and one was euthanized. All4 were submitted for necropsy to determine the cause of the clinical signs. Gross necropsy and histopathologic findings fromall birds resulted in a diagnosis of round cell neoplasia in multiple organs, including the skin, liver, kidney, and reproductivetract, with intranuclear inclusion bodies in the...
Source: Comparative Medicine - September 11, 2023 Category: Zoology Authors: Katherine A Shuster Tzushan S Yang Kate T Snyder Nicole Creanza Patrick K Mitchell Laura B Goodman Jennifer K Grenier Nicholas M Tataryn Lauren E Himmel Katherine N Gibson-Corley Source Type: research
Isolation and Characterization of a Novel Alpha-Hemolytic Streptococcus spp. from the Oral Cavity and Blood of Septicemic Periparturient Immunodeficient Mice
Comp Med. 2023 Sep 11. doi: 10.30802/AALAS-CM-23-000020. Online ahead of print.ABSTRACTMISTRG is an immunodeficient mouse strain that expresses multiple human cytokines that support hematopoietic stem cell maintenance and myelopoiesis. While establishing a breeding colony of MISTRG mice in a dedicated barrier room, 6 cases of death or disease occurred in pregnant or postpartum mice. Clinically, this manifested as hunched posture, dyspnea, and 1 case of emaciation with ataxia. Pathologic analysis of 7 mice revealed multisystemic necrosuppurative inflammation variably affecting the uterus and placenta, joints, meninges, inne...
Source: Comparative Medicine - September 11, 2023 Category: Zoology Authors: Amy Funk Qidong Jia Laura Janke Ashley Crawford Amy Iverson Jason Rosch Joseph Emmons Chandra Savage Heather Glasgow Randall Hayden Elisa Margolis Harshan Pisharath Source Type: research
Polyomavirus-associated Disseminated T-cell Lymphoma in a Colony of Zebra Finches (Taeniopygia guttata)
Comp Med. 2023 Sep 11. doi: 10.30802/AALAS-CM-23-000011. Online ahead of print.ABSTRACTFour zebra finches in a closed research colony presented with variable clinical signs, including masses, skin lesions,shivering, and/or ruffled feathers. These birds were not responsive to treatment efforts; 3 died and one was euthanized. All4 were submitted for necropsy to determine the cause of the clinical signs. Gross necropsy and histopathologic findings fromall birds resulted in a diagnosis of round cell neoplasia in multiple organs, including the skin, liver, kidney, and reproductivetract, with intranuclear inclusion bodies in the...
Source: Comparative Medicine - September 11, 2023 Category: Zoology Authors: Katherine A Shuster Tzushan S Yang Kate T Snyder Nicole Creanza Patrick K Mitchell Laura B Goodman Jennifer K Grenier Nicholas M Tataryn Lauren E Himmel Katherine N Gibson-Corley Source Type: research
Isolation and Characterization of a Novel Alpha-Hemolytic Streptococcus spp. from the Oral Cavity and Blood of Septicemic Periparturient Immunodeficient Mice
Comp Med. 2023 Sep 11. doi: 10.30802/AALAS-CM-23-000020. Online ahead of print.ABSTRACTMISTRG is an immunodeficient mouse strain that expresses multiple human cytokines that support hematopoietic stem cell maintenance and myelopoiesis. While establishing a breeding colony of MISTRG mice in a dedicated barrier room, 6 cases of death or disease occurred in pregnant or postpartum mice. Clinically, this manifested as hunched posture, dyspnea, and 1 case of emaciation with ataxia. Pathologic analysis of 7 mice revealed multisystemic necrosuppurative inflammation variably affecting the uterus and placenta, joints, meninges, inne...
Source: Comparative Medicine - September 11, 2023 Category: Zoology Authors: Amy Funk Qidong Jia Laura Janke Ashley Crawford Amy Iverson Jason Rosch Joseph Emmons Chandra Savage Heather Glasgow Randall Hayden Elisa Margolis Harshan Pisharath Source Type: research
Polyomavirus-associated Disseminated T-cell Lymphoma in a Colony of Zebra Finches (Taeniopygia guttata)
Comp Med. 2023 Sep 11. doi: 10.30802/AALAS-CM-23-000011. Online ahead of print.ABSTRACTFour zebra finches in a closed research colony presented with variable clinical signs, including masses, skin lesions,shivering, and/or ruffled feathers. These birds were not responsive to treatment efforts; 3 died and one was euthanized. All4 were submitted for necropsy to determine the cause of the clinical signs. Gross necropsy and histopathologic findings fromall birds resulted in a diagnosis of round cell neoplasia in multiple organs, including the skin, liver, kidney, and reproductivetract, with intranuclear inclusion bodies in the...
Source: Comparative Medicine - September 11, 2023 Category: Zoology Authors: Katherine A Shuster Tzushan S Yang Kate T Snyder Nicole Creanza Patrick K Mitchell Laura B Goodman Jennifer K Grenier Nicholas M Tataryn Lauren E Himmel Katherine N Gibson-Corley Source Type: research
Isolation and Characterization of a Novel Alpha-Hemolytic Streptococcus spp. from the Oral Cavity and Blood of Septicemic Periparturient Immunodeficient Mice
Comp Med. 2023 Sep 11. doi: 10.30802/AALAS-CM-23-000020. Online ahead of print.ABSTRACTMISTRG is an immunodeficient mouse strain that expresses multiple human cytokines that support hematopoietic stem cell maintenance and myelopoiesis. While establishing a breeding colony of MISTRG mice in a dedicated barrier room, 6 cases of death or disease occurred in pregnant or postpartum mice. Clinically, this manifested as hunched posture, dyspnea, and 1 case of emaciation with ataxia. Pathologic analysis of 7 mice revealed multisystemic necrosuppurative inflammation variably affecting the uterus and placenta, joints, meninges, inne...
Source: Comparative Medicine - September 11, 2023 Category: Zoology Authors: Amy Funk Qidong Jia Laura Janke Ashley Crawford Amy Iverson Jason Rosch Joseph Emmons Chandra Savage Heather Glasgow Randall Hayden Elisa Margolis Harshan Pisharath Source Type: research
Polyomavirus-associated Disseminated T-cell Lymphoma in a Colony of Zebra Finches (Taeniopygia guttata)
Comp Med. 2023 Sep 11. doi: 10.30802/AALAS-CM-23-000011. Online ahead of print.ABSTRACTFour zebra finches in a closed research colony presented with variable clinical signs, including masses, skin lesions,shivering, and/or ruffled feathers. These birds were not responsive to treatment efforts; 3 died and one was euthanized. All4 were submitted for necropsy to determine the cause of the clinical signs. Gross necropsy and histopathologic findings fromall birds resulted in a diagnosis of round cell neoplasia in multiple organs, including the skin, liver, kidney, and reproductivetract, with intranuclear inclusion bodies in the...
Source: Comparative Medicine - September 11, 2023 Category: Zoology Authors: Katherine A Shuster Tzushan S Yang Kate T Snyder Nicole Creanza Patrick K Mitchell Laura B Goodman Jennifer K Grenier Nicholas M Tataryn Lauren E Himmel Katherine N Gibson-Corley Source Type: research
Isolation and Characterization of a Novel Alpha-Hemolytic Streptococcus spp. from the Oral Cavity and Blood of Septicemic Periparturient Immunodeficient Mice
Comp Med. 2023 Sep 11. doi: 10.30802/AALAS-CM-23-000020. Online ahead of print.ABSTRACTMISTRG is an immunodeficient mouse strain that expresses multiple human cytokines that support hematopoietic stem cell maintenance and myelopoiesis. While establishing a breeding colony of MISTRG mice in a dedicated barrier room, 6 cases of death or disease occurred in pregnant or postpartum mice. Clinically, this manifested as hunched posture, dyspnea, and 1 case of emaciation with ataxia. Pathologic analysis of 7 mice revealed multisystemic necrosuppurative inflammation variably affecting the uterus and placenta, joints, meninges, inne...
Source: Comparative Medicine - September 11, 2023 Category: Zoology Authors: Amy Funk Qidong Jia Laura Janke Ashley Crawford Amy Iverson Jason Rosch Joseph Emmons Chandra Savage Heather Glasgow Randall Hayden Elisa Margolis Harshan Pisharath Source Type: research
Polyomavirus-associated Disseminated T-cell Lymphoma in a Colony of Zebra Finches (Taeniopygia guttata)
Comp Med. 2023 Sep 11. doi: 10.30802/AALAS-CM-23-000011. Online ahead of print.ABSTRACTFour zebra finches in a closed research colony presented with variable clinical signs, including masses, skin lesions,shivering, and/or ruffled feathers. These birds were not responsive to treatment efforts; 3 died and one was euthanized. All4 were submitted for necropsy to determine the cause of the clinical signs. Gross necropsy and histopathologic findings fromall birds resulted in a diagnosis of round cell neoplasia in multiple organs, including the skin, liver, kidney, and reproductivetract, with intranuclear inclusion bodies in the...
Source: Comparative Medicine - September 11, 2023 Category: Zoology Authors: Katherine A Shuster Tzushan S Yang Kate T Snyder Nicole Creanza Patrick K Mitchell Laura B Goodman Jennifer K Grenier Nicholas M Tataryn Lauren E Himmel Katherine N Gibson-Corley Source Type: research
Isolation and Characterization of a Novel Alpha-Hemolytic Streptococcus spp. from the Oral Cavity and Blood of Septicemic Periparturient Immunodeficient Mice
Comp Med. 2023 Sep 11. doi: 10.30802/AALAS-CM-23-000020. Online ahead of print.ABSTRACTMISTRG is an immunodeficient mouse strain that expresses multiple human cytokines that support hematopoietic stem cell maintenance and myelopoiesis. While establishing a breeding colony of MISTRG mice in a dedicated barrier room, 6 cases of death or disease occurred in pregnant or postpartum mice. Clinically, this manifested as hunched posture, dyspnea, and 1 case of emaciation with ataxia. Pathologic analysis of 7 mice revealed multisystemic necrosuppurative inflammation variably affecting the uterus and placenta, joints, meninges, inne...
Source: Comparative Medicine - September 11, 2023 Category: Zoology Authors: Amy Funk Qidong Jia Laura Janke Ashley Crawford Amy Iverson Jason Rosch Joseph Emmons Chandra Savage Heather Glasgow Randall Hayden Elisa Margolis Harshan Pisharath Source Type: research
Polyomavirus-associated Disseminated T-cell Lymphoma in a Colony of Zebra Finches (Taeniopygia guttata)
Comp Med. 2023 Sep 11. doi: 10.30802/AALAS-CM-23-000011. Online ahead of print.ABSTRACTFour zebra finches in a closed research colony presented with variable clinical signs, including masses, skin lesions,shivering, and/or ruffled feathers. These birds were not responsive to treatment efforts; 3 died and one was euthanized. All4 were submitted for necropsy to determine the cause of the clinical signs. Gross necropsy and histopathologic findings fromall birds resulted in a diagnosis of round cell neoplasia in multiple organs, including the skin, liver, kidney, and reproductivetract, with intranuclear inclusion bodies in the...
Source: Comparative Medicine - September 11, 2023 Category: Zoology Authors: Katherine A Shuster Tzushan S Yang Kate T Snyder Nicole Creanza Patrick K Mitchell Laura B Goodman Jennifer K Grenier Nicholas M Tataryn Lauren E Himmel Katherine N Gibson-Corley Source Type: research
Dietary Linoleic Acid: An Omega-6 Fatty Acid Essential for Liver Regeneration in Buffalo Rats
Comp Med. 2023 Aug 31. doi: 10.30802/AALAS-CM-23-000004. Online ahead of print.ABSTRACTRodents are currently the most common animals used for hepatic surgical resection studies that investigate liver regeneration,chronic liver disease, acute liver failure, hepatic metastasis, hepatic function, and hepatic cancer. Our previous workhas shown that dietary consumption of linoleic acid (LA) stimulates the growth of rodent and human tumors in vivo. Herewe compared 3 diets─a 5% corn oil diet (control), a diet deficient in essential fatty acids (EFAD), and an EFAD supplementedwith LA in amounts equal to those in the control diet...
Source: Comparative Medicine - August 31, 2023 Category: Zoology Authors: Robert T Dauchy Leonard A Sauer David E Blask Source Type: research
Dietary Linoleic Acid: An Omega-6 Fatty Acid Essential for Liver Regeneration in Buffalo Rats
Comp Med. 2023 Aug 31. doi: 10.30802/AALAS-CM-23-000004. Online ahead of print.ABSTRACTRodents are currently the most common animals used for hepatic surgical resection studies that investigate liver regeneration,chronic liver disease, acute liver failure, hepatic metastasis, hepatic function, and hepatic cancer. Our previous workhas shown that dietary consumption of linoleic acid (LA) stimulates the growth of rodent and human tumors in vivo. Herewe compared 3 diets─a 5% corn oil diet (control), a diet deficient in essential fatty acids (EFAD), and an EFAD supplementedwith LA in amounts equal to those in the control diet...
Source: Comparative Medicine - August 31, 2023 Category: Zoology Authors: Robert T Dauchy Leonard A Sauer David E Blask Source Type: research
Dietary Linoleic Acid: An Omega-6 Fatty Acid Essential for Liver Regeneration in Buffalo Rats
Comp Med. 2023 Aug 31. doi: 10.30802/AALAS-CM-23-000004. Online ahead of print.ABSTRACTRodents are currently the most common animals used for hepatic surgical resection studies that investigate liver regeneration,chronic liver disease, acute liver failure, hepatic metastasis, hepatic function, and hepatic cancer. Our previous workhas shown that dietary consumption of linoleic acid (LA) stimulates the growth of rodent and human tumors in vivo. Herewe compared 3 diets─a 5% corn oil diet (control), a diet deficient in essential fatty acids (EFAD), and an EFAD supplementedwith LA in amounts equal to those in the control diet...
Source: Comparative Medicine - August 31, 2023 Category: Zoology Authors: Robert T Dauchy Leonard A Sauer David E Blask Source Type: research
