Letter to the Editor
Comp Med. 2023 Apr 1;73(2):107.NO ABSTRACTPMID:37170457 | PMC:PMC10162379 (Source: Comparative Medicine)
Source: Comparative Medicine - May 12, 2023 Category: Zoology Authors: Jake Murkin Ana I Faustino-Rocha Paula A Oliveira Source Type: research
The Aalas Journals: Opinions
Comp Med. 2023 Apr 1;73(2):108.NO ABSTRACTPMID:37170456 | PMC:PMC10162373 (Source: Comparative Medicine)
Source: Comparative Medicine - May 12, 2023 Category: Zoology Authors: Linda A Toth Source Type: research
Letter to the Editor
Comp Med. 2023 Apr 1;73(2):107.NO ABSTRACTPMID:37170457 | PMC:PMC10162379 (Source: Comparative Medicine)
Source: Comparative Medicine - May 12, 2023 Category: Zoology Authors: Jake Murkin Ana I Faustino-Rocha Paula A Oliveira Source Type: research
The Aalas Journals: Opinions
Comp Med. 2023 Apr 1;73(2):108.NO ABSTRACTPMID:37170456 | PMC:PMC10162373 (Source: Comparative Medicine)
Source: Comparative Medicine - May 12, 2023 Category: Zoology Authors: Linda A Toth Source Type: research
Letter to the Editor
Comp Med. 2023 Apr 1;73(2):107.NO ABSTRACTPMID:37170457 | PMC:PMC10162379 (Source: Comparative Medicine)
Source: Comparative Medicine - May 12, 2023 Category: Zoology Authors: Jake Murkin Ana I Faustino-Rocha Paula A Oliveira Source Type: research
The Aalas Journals: Opinions
Comp Med. 2023 Apr 1;73(2):108.NO ABSTRACTPMID:37170456 | PMC:PMC10162373 (Source: Comparative Medicine)
Source: Comparative Medicine - May 12, 2023 Category: Zoology Authors: Linda A Toth Source Type: research
Letter to the Editor
Comp Med. 2023 Apr 1;73(2):107.NO ABSTRACTPMID:37170457 | PMC:PMC10162379 (Source: Comparative Medicine)
Source: Comparative Medicine - May 12, 2023 Category: Zoology Authors: Jake Murkin Ana I Faustino-Rocha Paula A Oliveira Source Type: research
The Aalas Journals: Opinions
Comp Med. 2023 Apr 1;73(2):108.NO ABSTRACTPMID:37170456 | PMC:PMC10162373 (Source: Comparative Medicine)
Source: Comparative Medicine - May 12, 2023 Category: Zoology Authors: Linda A Toth Source Type: research
Letter to the Editor
Comp Med. 2023 Apr 1;73(2):107.NO ABSTRACTPMID:37170457 | PMC:PMC10162379 (Source: Comparative Medicine)
Source: Comparative Medicine - May 12, 2023 Category: Zoology Authors: Jake Murkin Ana I Faustino-Rocha Paula A Oliveira Source Type: research
The Aalas Journals: Opinions
Comp Med. 2023 Apr 1;73(2):108.NO ABSTRACTPMID:37170456 (Source: Comparative Medicine)
Source: Comparative Medicine - May 12, 2023 Category: Zoology Authors: Linda A Toth Source Type: research
Letter to the Editor
Comp Med. 2023 Apr 1;73(2):107.NO ABSTRACTPMID:37170457 (Source: Comparative Medicine)
Source: Comparative Medicine - May 12, 2023 Category: Zoology Authors: Jake Murkin Ana I Faustino-Rocha Paula A Oliveira Source Type: research
Bioactivity and Pharmacodynamics of X002, a Follicle-stimulating Hormone-IgG4 Fc Fusion Protein
Comp Med. 2023 Apr 1;73(2):145-52. doi: 10.30802/AALAS-CM-22-000001. Online ahead of print.ABSTRACTCurrent follicle-stimulating hormone (FSH) drugs meet safety criteria but have suboptimal efficacy, poor patient compliance, and high cost. Alternative FSH-like drugs would help to meet the high market demand. Here, we evaluated X002, an FSH-Fc fusion protein, for bioactivity and half-life in vitro and in vivo. In all cases, the effects of X002 were compared with those of a commercially available short-acting FSH recombinant hormone. First, female Kunming mice (age, 21 to 24 d) were stimulated with pregnant mare serum gonadot...
Source: Comparative Medicine - April 18, 2023 Category: Zoology Authors: Guili Xu Yi Yang Yunhui Liu Fang Chen Lihou Dong Deyou Wan Hongjie Li Cuima Yang Xin Gao Source Type: research
Bioactivity and Pharmacodynamics of X002, a Follicle-stimulating Hormone-IgG4 Fc Fusion Protein
Comp Med. 2023 Apr 1;73(2):145-52. doi: 10.30802/AALAS-CM-22-000001. Online ahead of print.ABSTRACTCurrent follicle-stimulating hormone (FSH) drugs meet safety criteria but have suboptimal efficacy, poor patient compliance, and high cost. Alternative FSH-like drugs would help to meet the high market demand. Here, we evaluated X002, an FSH-Fc fusion protein, for bioactivity and half-life in vitro and in vivo. In all cases, the effects of X002 were compared with those of a commercially available short-acting FSH recombinant hormone. First, female Kunming mice (age, 21 to 24 d) were stimulated with pregnant mare serum gonadot...
Source: Comparative Medicine - April 18, 2023 Category: Zoology Authors: Guili Xu Yi Yang Yunhui Liu Fang Chen Lihou Dong Deyou Wan Hongjie Li Cuima Yang Xin Gao Source Type: research
Bioactivity and Pharmacodynamics of X002, a Follicle-stimulating Hormone-IgG4 Fc Fusion Protein
Comp Med. 2023 Apr 1;73(2):145-52. doi: 10.30802/AALAS-CM-22-000001. Online ahead of print.ABSTRACTCurrent follicle-stimulating hormone (FSH) drugs meet safety criteria but have suboptimal efficacy, poor patient compliance, and high cost. Alternative FSH-like drugs would help to meet the high market demand. Here, we evaluated X002, an FSH-Fc fusion protein, for bioactivity and half-life in vitro and in vivo. In all cases, the effects of X002 were compared with those of a commercially available short-acting FSH recombinant hormone. First, female Kunming mice (age, 21 to 24 d) were stimulated with pregnant mare serum gonadot...
Source: Comparative Medicine - April 18, 2023 Category: Zoology Authors: Guili Xu Yi Yang Yunhui Liu Fang Chen Lihou Dong Deyou Wan Hongjie Li Cuima Yang Xin Gao Source Type: research
Bioactivity and Pharmacodynamics of X002, a Follicle-stimulating Hormone-IgG4 Fc Fusion Protein
Comp Med. 2023 Apr 1;73(2):145-52. doi: 10.30802/AALAS-CM-22-000001. Online ahead of print.ABSTRACTCurrent follicle-stimulating hormone (FSH) drugs meet safety criteria but have suboptimal efficacy, poor patient compliance, and high cost. Alternative FSH-like drugs would help to meet the high market demand. Here, we evaluated X002, an FSH-Fc fusion protein, for bioactivity and half-life in vitro and in vivo. In all cases, the effects of X002 were compared with those of a commercially available short-acting FSH recombinant hormone. First, female Kunming mice (age, 21 to 24 d) were stimulated with pregnant mare serum gonadot...
Source: Comparative Medicine - April 18, 2023 Category: Zoology Authors: Guili Xu Yi Yang Yunhui Liu Fang Chen Lihou Dong Deyou Wan Hongjie Li Cuima Yang Xin Gao Source Type: research