Modulation of faecal miRNAs highlights the preventive effects of a Mediterranean Low-Inflammatory Dietary Intervention
Dietary interventions have been proposed as therapeutic approaches for several diseases, including cancer. A low-inflammatory Mediterranean dietary intervention, conducted as a pilot study in subjects with Familial Adenomatous Polyposis (FAP), reduced markers of local and systemic inflammation. We aim to determine whether this diet may modulate faecal microRNA (miRNA) and gene expression in the gut. (Source: Clinical Nutrition)
Source: Clinical Nutrition - February 25, 2024 Category: Nutrition Authors: Oscar Illescas, Giulio Ferrero, Antonino Belfiore, Barbara Pardini, Sonia Tarallo, Chiara M. Ciniselli, Sara Noci, Elena Daveri, Stefano Signoroni, Laura Cattaneo, Andrea Mancini, Daniele Morelli, Massimo Milione, Francesca Cordero, Licia Rivoltini, Paolo Tags: Original article Source Type: research
Assessment of muscle endocrine function and inflammatory signalling in male school children following a physical activity programme.
The objective of this study was to determine the effect of a vigorous physical activity intervention on endocrine muscle function and cytokine output in children. (Source: Clinical Nutrition)
Source: Clinical Nutrition - February 25, 2024 Category: Nutrition Authors: Javier Diaz-Castro, Daniela Reyes-Olavarr ía, Juan M. Toledano, María Puche-Juarez, Jose Eulogio Garcia-Vega, Julio J. Ochoa, Jorge Moreno-Fernandez Tags: Original article Source Type: research
The clinical significance of hypoalbuminaemia
Albumin is a relatively small molecule with a radius of 7.5 nm and a molecular weight of 65 kDa. It is the most abundant protein in plasma, accounting for 60–75% of its oncotic pressure. Its concentration in plasma is merely one static measurement reflecting a dynamic and complex system of albumin physiology, and is the net result of several different p rocesses, one or more of which may become deranged by disease or its treatment. It is also unsurprising that hypoalbuminaemia has proved to be an indicator of morbidity and mortality risk since the underlying conditions which cause it, including protein energy malnutri...
Source: Clinical Nutrition - February 22, 2024 Category: Nutrition Authors: Simon P. Allison, Dileep N. Lobo Tags: Opinion paper Source Type: research
Association of a low-inflammatory diet with survival among adults: The role of cardiometabolic diseases and lifestyle
Evidence on the association between dietary inflammation and longevity is limited. We aimed to examine the association of a low-inflammatory diet with mortality and longevity, and to explore whether cardiometabolic diseases (CMDs) and lifestyle factors may play a role in this association. (Source: Clinical Nutrition)
Source: Clinical Nutrition - February 22, 2024 Category: Nutrition Authors: Huiying Da, Rongrong Yang, Jiaxin Liang, Jiao Wang, Wenzhe Yang, Michelle M. Dunk, Xiuying Qi, Weili Xu Tags: Original article Source Type: research
Glycemic variability assessed using continuous glucose monitoring in individuals without diabetes and associations with cardiometabolic risk markers: a systematic review and meta-analysis
Continuous glucose monitoring (CGM) provides data on short-term glycemic variability (GV). GV is associated with adverse outcomes in individuals with diabetes. Whether GV is associated with cardiometabolic risk in individuals without diabetes is unclear. We systematically reviewed the literature to assess whether GV is associated with cardiometabolic risk markers or outcomes in individuals without diabetes. (Source: Clinical Nutrition)
Source: Clinical Nutrition - February 20, 2024 Category: Nutrition Authors: Anna Hjort, David Iggman, Fredrik Rosqvist Tags: Meta-analyses Source Type: research
Effect of dietary interventions on nutritional status in patients with rheumatoid arthritis and spondyloarthritis - A systematic review and meta-analysis.
Patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA) have an increased risk of developing altered body composition, such as low muscle mass, and an increased risk of developing cardiovascular diseases (CVD).Thus, investigating how to improve body composition and CVD risk factors is a relevant topic to improve management of RA and SpA. The aim of this study was to identify dietary interventions that can improve body composition, as well as reduce CVD risk factors in RA and SpA. (Source: Clinical Nutrition)
Source: Clinical Nutrition - February 20, 2024 Category: Nutrition Authors: Marie Njerve Olsen, Anne-Kristine Halse, Elisabeth Skeie, Regina K üfner Lein, Roy M. Nilsen, Randi J. Tangvik Tags: Meta-analyses Source Type: research
Quantifying the Severity of Sarcopenia in Patients with Cancer of the Head and Neck
In this study we aimed to define criterion values for moderate and severe skeletal muscle depletion based on the risk of mortality in a population of patients with head and neck cancer (HNC). Additionally, we aimed to identify clinical and demographic predictors of skeletal muscle depletion, evaluate the survival impact of skeletal muscle depletion in patients with minimal nutritional risk or good performance status, and finally, benchmarking SMI values of patients with HNC against healthy young adults. (Source: Clinical Nutrition)
Source: Clinical Nutrition - February 20, 2024 Category: Nutrition Authors: Catherine Kubrak, Lisa Martin, Aaron J. Grossberg, Brennan Olson, Faith Ottery, Merran Findlay, Judith D. Bauer, Naresh Jha, Rufus Scrimger, Brock Debenham, Neil Chua, John Walker, Vickie Baracos Tags: Original article Source Type: research
Clinical nutrition in primary care: ESPEN position paper
Primary care healthcare professionals (PCHPs) are pivotal in managing chronic diseases and present a unique opportunity for nutrition-related disease prevention. However, the active involvement of PCHPs in nutritional care is limited, influenced by factors like insufficient education, lack of resources, and time constraints. In this position paper The European Society for Clinical Nutrition and Metabolism (ESPEN) promotes the active engagement of PCHPs in nutritional care. We emphasize the importance of early detection of malnutrition by screening and diagnosis, particularly in all individuals presenting with risk factors ...
Source: Clinical Nutrition - February 20, 2024 Category: Nutrition Authors: Željko Krznarić, Darija Vranešić Bender, Milena Blaž Kovač, Cristina Cuerda, Annemieke van Ginkel-Res, Michael Hiesmayr, Anibal Marinho, Juan Mendive, Isabel Monteiro, Matthias Pirlich, Sanja Music Milanovic, Nada Rotovnik Kozjek, Stephane Schneider Tags: Editorial Source Type: research
Red Cell Distribution Width: as a nutritional risk biomarker; practical or historical?
(Source: Clinical Nutrition)
Source: Clinical Nutrition - February 16, 2024 Category: Nutrition Authors: G özde Şengül Ayçiçek Tags: Letter to the Editor Source Type: research
Circulating MicroRNA-19 and Cardiovascular Risk Reduction in Response to Weight-loss Diets
We examined whether change in circulating miR-19 was associated with change in CVD risk during weight loss. (Source: Clinical Nutrition)
Source: Clinical Nutrition - February 15, 2024 Category: Nutrition Authors: Qiaochu Xue, Yoriko Heianza, Xiang Li, Xuan Wang, Hao Ma, Jennifer Rood, Kirsten S. Dorans, Katherine T. Mills, Xiaowen Liu, George A. Bray, Frank M. Sacks, Lu Qi Tags: Original article Source Type: research
The Effect of Chrono-Nutritional Manipulation of Carbohydrate Intake on Sleep Macrostructure: a Randomized Controlled Trial
Over the years, there is a rapid increase in the prevalence of inadequate sleep and its detrimental consequences. Yet, the impact of prolonged nutritional interventions on sleep optimization remains unexplored. (Source: Clinical Nutrition)
Source: Clinical Nutrition - February 14, 2024 Category: Nutrition Authors: Angelos Vlahoyiannis, Eleni Andreou, Panagiotis Bargiotas, George Aphamis, Giorgos K. Sakkas, Christoforos D. Giannaki Tags: Randomized Control Trials Source Type: research
Red blood cell distribution width is an inflammatory but not a nutritional biomarker
(Source: Clinical Nutrition)
Source: Clinical Nutrition - February 13, 2024 Category: Nutrition Authors: Jialu Wang, Renying Xu Tags: Letter to the Editor Source Type: research
Reply-Letter to the Editor - Red blood cell distribution width is an inflammatory but not a nutritional biomarker
(Source: Clinical Nutrition)
Source: Clinical Nutrition - February 13, 2024 Category: Nutrition Authors: Philipp Schuetz, Eliane Haenggi, Carla Wunderle Tags: Letter to the Editor Source Type: research
Zinc unbound concentration as an anchor to drive individualize repletion
Zinc (Zn) quantification is of particular interest in many clinical condition (e.g. inflammatory disease, critical care). Currently, Zn status is assessed by measuring plasma/serum concentration. This concentration corresponds to the sum of unbound Zn (Zn –Cu) and Zn highly bound to albumin (Zn-Cb). (Source: Clinical Nutrition)
Source: Clinical Nutrition - February 12, 2024 Category: Nutrition Authors: D. Metsu, C. Cinq-Frais, C. Camare, S. Caspar-Bauguil, A. Galinier Tags: Opinion paper Source Type: research
Direct oral and fiber-derived butyrate supplementation as an anti-obesity treatment via different targets
Butyrate (one of the short-chain fatty acids), a major byproduct of the fermentation of non-digestible carbohydrates (e.g. fiber), is supposed to have anti-obesity and anti-inflammatory properties. However, butyrate ’s potential and mechanism in preventing obesity and the efficient form of administration remain to be clarified. (Source: Clinical Nutrition)
Source: Clinical Nutrition - February 12, 2024 Category: Nutrition Authors: Zuzanna Majka, Barbara Zapala, Agnieszka Krawczyk, Krzysztof Czamara, Joanna Mazurkiewicz, Ewa Stanek, Izabela Czyzynska-Cichon, Mariusz Kepczynski, Dominika Salamon, Tomasz Gosiewski, Agnieszka Kaczor Tags: Original article Source Type: research
