Dose-dependent effects of enteral nutrition on the faecal microbiota and short chain fatty acids
Enteral nutrition (EN) involves replacing all or part of a person ’s habitual diet with a nutritional formula. The impact of varying doses of EN on the gut microbiome remains understudied. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 8, 2024 Category: Nutrition Authors: Aleksandra Jatkowska, Konstantinos Gkikas, Ben Nichols, Bryn Short, Vasiliki-Konstantina Rizou, Panagiotis Kapranos, Jennifer Klein Gunnewiek, Edelyn Christina, Vaios Svolos, Christopher Quince, Konstantinos Gerasimidis Source Type: research

The role of the aryl hydrocarbon receptor (AhR) in modulating intestinal ILC3s to optimise gut pathogen resistance in lupus and benefits of nutritional AhR ligands.
Dysbiosis is emerging as a potential trigger of systemic lupus erythematosus (SLE). Group 3 innate lymphoid cells (ILC3s) are recognised as key regulators of intestinal homeostasis. The aryl hydrocarbon receptor (AhR) is critical to intestinal ILC3 development and function. This mechanistic review aimed to investigate whether AhR activation of gut ILC3s facilitates IL-22-mediated antimicrobial peptide (AMP) production to enhance colonisation resistance and ameliorate SLE pathology associated with intestinal dysbiosis. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 8, 2024 Category: Nutrition Authors: Niamh Hanlon, Natalie Gillan, James Neil, Karin Seidler Source Type: research

β-hydroxybutyrate exposure restores mitochondrial function in skeletal muscle satellite cells of critically ill patients
This study aimed to elucidate the distinct metabolic effects of critical illness and β-OHB on satellite cells isolated from these patients. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 8, 2024 Category: Nutrition Authors: Lucie Genserov á, František Duška, Adéla Krajčová Source Type: research

Association of added sugar intake and its forms and sources with handgrip strength decline among middle-aged and older adults: A prospective cohort study
This study aimed to investigate the association between added sugar intake and longitudinal changes in handgrip strength among middle-aged and elderly Chinese adults. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 4, 2024 Category: Nutrition Authors: Lin Zhu, Yeqing Gu, Jianguo Li, Shuna Yu, Jinhan Wang, Hongmei Wu, Ge Meng, Xuena Wang, Qing Zhang, Li Liu, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Kun Song, Qiang Liu, Kaijun Niu Tags: Original article Source Type: research

Prognosis of Patients With Coexisting Obesity and Malnutrition After Ischemic Stroke: A Cohort Study
The double burden of malnutrition, defined as the coexistence of obesity and malnutrition, is an increasing global health concern and is unclear in patients after ischemic stroke. The current study explored the combined impacts of obesity and malnutrition on patients with ischemic stroke. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 4, 2024 Category: Nutrition Authors: Huicong Niu, Min Chu, Ning Yang, Daosheng Wang, Yang Liu, Xueyu Mao, Shiliang Xia, Delong Wang, Xuechun Wu, Jing Zhao Tags: Original article Source Type: research

The potential of machine learning models to identify malnutrition diagnosed by GLIM combined with NRS-2002 in colorectal cancer patients without weight loss information
The key step of the Global Leadership Initiative on Malnutrition (GLIM) is nutritional risk screening, while the most appropriate screening tool for colorectal cancer (CRC) patients is yet unknown. The GLIM diagnosis relies on weight loss information, and bias or even failure to recall patients ’ historical weight can cause misestimates of malnutrition. We aimed to compare the suitability of several screening tools in GLIM diagnosis, and establish machine learning (ML) models to predict malnutrition in CRC patients without weight loss information. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 4, 2024 Category: Nutrition Authors: Tiantian Wu, Hongxia Xu, Wei Li, Fuxiang Zhou, Zengqing Guo, Kunhua Wang, Min Weng, Chunling Zhou, Ming Liu, Yuan Lin, Suyi Li, Ying He, Qinghua Yao, Hanping Shi, Chunhua Song, The Investigation on Nutrition Status and its Clinical Outcome of Common Cance Tags: Original article Source Type: research

The infant gut microbiome and cognitive development in malnutrition
Malnutrition affects 195 million children under the age of five worldwide with long term effects that include impaired cognitive development. Brain development occurs rapidly over the first 36 months of life. Whilst seemingly independent, changes to the brain and gut microbiome are linked by metabolites, hormones, and neurotransmitters as part of the gut-brain axis. In the context of severe malnutrition, the composition of the gut microbiome and the repertoire of biochemicals exchanged via the gut-brain axis vary when compared to healthy individuals. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 3, 2024 Category: Nutrition Authors: Inoli Shennon, B.C. Wilson, A.H. Behling, T. Portlock, R. Haque, T. Forrester, C.A. Nelson, J.M. O ’Sullivan, M4EFaD consortium Tags: Narrative Review Source Type: research

Effect of a 12-WEEK nutritional intervention in the food intake of patients on the waiting list for liver transplantation: A secondary analysis of a randomized controlled trial
Inadequate food intake contributes to malnutrition in patients with cirrhosis on the waiting list for liver transplantation (LTx). (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 3, 2024 Category: Nutrition Authors: Samanta Catherine Ferreira, Amanda de Souza Rezende Cardoso, Arimluz de Almeida Santos, Lucilene Rezende Anast ácio Tags: Original article Source Type: research

The Complementary Roles of Iron and Estrogen in Menopausal Differences in Cardiometabolic Outcomes
Biological hormonal changes are frequently cited as an explanatory factor of sex and menopause differences in cardiometabolic diseases (CMD) and its associated risk factors. However, iron metabolism which varies between sexes and among women of different reproductive stages could also play a role. Recent evidence suggest that iron may contribute to CMD risk by modulating oxidative stress pathways and inflammatory responses, offering insights into the mechanistic interplay between iron and CMD development. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 3, 2024 Category: Nutrition Authors: Noushin Sadat Ahanchi, Farnaz Khatami, Erand Llanaj, Hugo G. Quezada-Pinedo, Helga Dizdari, Arjola Bano, Marija Glisic, Michele F. Eisenga, Pedro-Marques Vidal, Taulant Muka Tags: Narrative Review Source Type: research

Arachidonic acid and docosahexaenoic acid levels correlate with the inflammation proteome in extremely preterm infants
This study aimed to determine associations between DHA, AA, and inflammation-related proteins during the neonatal period in extremely preterm infants. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 3, 2024 Category: Nutrition Authors: Susanna Klevebro, Simon Kebede Merid, Ulrika Sj öbom, Wen Zhong, Hanna Danielsson, Dirk Wackernagel, Ingrid Hansen-Pupp, David Ley, Karin Sävman, Mathias Uhlén, Lois EH. Smith, Ann Hellström, Anders K. Nilsson Tags: Original article Source Type: research

Prevalence of Sarcopenic Obesity According to Different Diagnostic Methods and Cut-Off Points in Candidates for Bariatric Surgery
Sarcopenic obesity (SO) is defined as a combination of low strength and muscle mass along with excess adiposity. Our study aimed to determine the prevalence of sarcopenic obesity in candidates for bariatric surgery, according to ESPEN/EASO criteria using bioimpedance analysis (BIA) and dual-energy X-ray absorptiometry (DXA). (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 1, 2024 Category: Nutrition Authors: Elena Gonz ález Arnáiz, Diana Ariadel Cobo, Brisamar Estébanez, David Barajas Galindo, Begoña Pintor de la Maza, Ana Urioste Fondo, Carmen Dameto Pons, María J. Cuevas, María D. Ballesteros Pomar Tags: Original article Source Type: research

Difference in association of carbohydrate intake with all-cause mortality between middle-aged and older Korean adults with and without diabetes mellitus: A prospective study
The relationship between diet and health, particularly the role of carbohydrates, has been extensively studied. However, carbohydrate intake based on individual health conditions remains unclear. Here, we aimed to investigate whether the association between carbohydrate intake and all-cause mortality varied between individuals with and without diabetes mellitus (DM). (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 1, 2024 Category: Nutrition Authors: Young-Hwan Park, Hye Sun Lee, Juyeon Yang, Li Rang Lim, Yu-Jin Kwon, Ji-Won Lee Tags: Original article Source Type: research

Adherence to the ultra-processed dietary pattern and risk of depressive outcomes: findings from the NutriNet Brasil cohort study and an updated systematic review and meta-analysis
We aimed to analyze the prospective association between adherence to the ultra-processed dietary pattern and risk of depressive outcomes using original data from the NutriNet Brasil cohort and via a systematic review and meta-analysis of observational studies that have investigated the same association. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 1, 2024 Category: Nutrition Authors: Andr é O. Werneck, Euridice M. Steele, Felipe M. Delpino, Melissa M. Lane, Wolfgang Marx, Felice N. Jacka, Brendon Stubbs, Mathilde Touvier, Bernard Srour, Maria LC. Louzada, Renata B. Levy, Carlos A. Monteiro Tags: Original article Source Type: research

Geriatric nutritional risk index as a predictor for fragility fracture risk in elderly with type 2 diabetes mellitus: A 9-year ambispective longitudinal cohort study
This study aims to delve into the association between the GNRI and a fragility fracture and the 10-year probability of hip fracture (HF) and major osteoporotic fracture (MOF) evaluated by FRAX in elderly with T2DM. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 1, 2024 Category: Nutrition Authors: Jiangmei Pan, Guoling Xu, Zhenwei Zhai, Jingxia Sun, Qiu Wang, Xiuxian Huang, Yanli Guo, Quan Lu, Jianming Mo, Yuechou Nong, Jianhao Huang, Wensheng Lu Tags: Original article Source Type: research

Comment on: “effects of resistance training on sarcopenia in patients with intestinal failure: A randomized controlled trial”
We have read with interest the article published by Xiao Y et  al. [1]. This is a very meaningful research and has a good guiding role in clinical practice. Although we believe it is a very interesting topic, we would like to offer the following points for your consideration. (Source: Clinical Nutrition)
Source: Clinical Nutrition - March 31, 2024 Category: Nutrition Authors: Jingjing Yu, Qiang Hu Tags: Letter to the Editor Source Type: research