Reply – Letter to the editor: Reconsidering 1.2–1.5 g/kg as beneficially high protein provision in critically ill patients
We thank Lee et  al. for their interest in our systematic review and meta-analysis (SRMA) [1]. As discussed in our SRMA, the vast majority of observational studies had at least a serious risk of bias due to confounding, which underlies the nature of the study design. We upfront decided to include a wide variety of study designs to specifically evaluate the current support for the guideline of ≥1.2 g/kg of protein, which lacks sufficient RCT's. The risk of publication bias was assessed by visual inspection of funnel plots and Egger's tests (Supplementary File 4). (Source: Clinical Nutrition)
Source: Clinical Nutrition - November 28, 2023 Category: Nutrition Authors: Isabel M. van Ruijven, Anja H. Brunsveld-Reinders, Sandra N. Stapel, Peter J.M. Weijs Tags: Letter to the Editor Source Type: research

Comment on “Chronotype as a predictor of weight loss and body composition improvements in women with overweight or obesity undergoing a very low-calorie ketogenic diet (VLCKD)” Clinical Nutrition 2023
(Source: Clinical Nutrition)
Source: Clinical Nutrition - November 28, 2023 Category: Nutrition Authors: Ingrid Thayanne Souza Alves da Silva, D ébora Eduarda da Silva Fidelis, Matheus Santos de Sousa Fernandes Tags: Letter to the Editor Source Type: research

Reply – Letter to the Editor: Reconsidering 1.2-1.5 g/kg as beneficially high protein provision in critically ill patients
(Source: Clinical Nutrition)
Source: Clinical Nutrition - November 28, 2023 Category: Nutrition Authors: Isabel M. van Ruijven, Anja H. Brunsveld-Reinders, Sandra N. Stapel, Peter J.M. Weijs Tags: Letter to the Editor Source Type: research

Guidance for Assessment of the Inflammation Etiologic Criterion for the Global Leadership Initiative (GLIM) on Diagnosis of Malnutrition: A Modified Delphi Approach
The Global Leadership Initiative on Malnutrition (GLIM) approach to malnutrition diagnosis is based on assessment of three phenotypic (weight loss, low body mass index, and reduced skeletal muscle mass) and two etiologic (reduced food intake/assimilation and disease burden/inflammation) criteria, with diagnosis confirmed by fulfillment of any combination of at least one phenotypic and at least one etiologic criterion. The original GLIM description provided limited guidance regarding assessment of inflammation and this has been a factor impeding further implementation of the GLIM criteria. (Source: Clinical Nutrition)
Source: Clinical Nutrition - November 28, 2023 Category: Nutrition Authors: Tommy Cederholm, Gordon L. Jensen, Maria D. Ballesteros-Pomar, Renee Blaauw, M. Isabel T.D. Correia, Cristina Cuerda, David C. Evans, Ryoji Fukushima, Juan Bernardo Ochoa Gautier, M. Cristina Gonzalez, Andre van Gossum, Leah Gramlich, Joseph Hartono, Stev Tags: ESPEN Endorsed Recommendation Source Type: research

Reply-Letter to the editor
(Source: Clinical Nutrition)
Source: Clinical Nutrition - November 28, 2023 Category: Nutrition Authors: Yaqin Xiao, Xuejin Gao, Xinying Wang Tags: Letter to the Editor Source Type: research

Arachidonic and Docosahexaenoic Acid Supplementation and Brain Maturation in Preterm Infants; a double blind RCT
&Aim: Arachidonic acid (ARA) and docosahexaenoic acid (DHA) are important structural components of neural cellular membranes and possess anti-inflammatory properties. Very preterm infants are deprived of the enhanced placental supply of these fatty acids, but the benefit of postnatal supplementation on brain development is uncertain. The aim of this study was to test the hypothesis that early enteral supplementation with ARA and DHA in preterm infants improves white matter (WM) microstructure assessed by diffusion-weighted MRI at term equivalent age. (Source: Clinical Nutrition)
Source: Clinical Nutrition - November 28, 2023 Category: Nutrition Authors: Sissel J. Moltu, Tone Nordvik, Madelaine E. Rossholt, Kristina Wendel, Maninder Chawla, Andres Server, Gunnthorunn Gunnarsdottir, Are Hugo Pripp, Magnus Domell öf, Marianne Bratlie, Marlen Aas, Petra S. Hüppi, Alexandre Lapillonne, Mona K. Beyer, Tom St Tags: Randomized Control Trials Source Type: research

Milk fat globule membrane modulates inflammatory pathways in human monocytes: a crossover human intervention study
Intake of high-fat foods raises postprandial plasma triglycerides and inflammatory markers, which may depend on the type of fat ingested. Dairy products are commonly consumed, but not much is known about the impact of milk fat and the milk fat globule membrane on postprandial inflammation. Here, we aimed to study the effect of milk fat with and without milk fat globule membrane and vegetable blend fat on post-prandial inflammation, with a focus on blood monocyte gene expression. (Source: Clinical Nutrition)
Source: Clinical Nutrition - November 28, 2023 Category: Nutrition Authors: Lei Deng, Charlotte C.J.R. Michelsen, Frank Vrieling, Guido J.E.J. Hooiveld, Rinke Stienstra, Anouk L. Feitsma, Sander Kersten, Lydia A. Afman Tags: Original article Source Type: research

Superior vena cava syndrome in chronic intestinal failure patients: when the going gets tough
In this study, we aimed to determine the incidence of SVCS in HPN patients and describe SVCS-related outcomes. (Source: Clinical Nutrition)
Source: Clinical Nutrition - November 28, 2023 Category: Nutrition Authors: V.E.L.M. Gillis, J.W. Korzilius, Y. Wouters, S.F.M. Jenniskens, G.J.A. Wanten Tags: Original article Source Type: research

The importance of ethnic-specific cut-offs of low muscle mass for survival prediction in oncology
While skeletal muscle index (SMI) is the most widely used indicator of low muscle mass (or sarcopenia) in oncology, optimal cut-offs (or definitions) to better predict survival are not standardized. (Source: Clinical Nutrition)
Source: Clinical Nutrition - November 27, 2023 Category: Nutrition Authors: Satoru Taguchi, Kotaro Sugawara, Wataru Gonoi, Shouhei Hanaoka, Shinichiro Shiomi, Kenjiro Kishitani, Yukari Uemura, Nobuhiko Akamatsu, Shohei Inui, Koji Tanaka, Koichi Yagi, Taketo Kawai, Tohru Nakagawa, Hiroshi Fukuhara, Osamu Abe, Yasuyuki Seto, M. Cri Tags: Original article Source Type: research

Nutritional status as prognostic factor of advanced oesophageal cancer patients treated with immune checkpoint inhibitors
In this study, we explored the associations between pretreatment nutrition-related indicators and clinical outcomes in patients with advanced EC who were treated with immune checkpoint inhibitors (ICIs). (Source: Clinical Nutrition)
Source: Clinical Nutrition - November 27, 2023 Category: Nutrition Authors: Ning Chen, Ying Yu, Wanji Shen, Xiaoling Xu, Yun Fan Tags: Original article Source Type: research

Gene variants and the response to childhood obesity interventions: A systematic review and meta-analysis
Multiple lifestyle-based childhood obesity interventions have been conducted to address childhood obesity, but individual ’s response to the universal intervention approach varied greatly. Whether gene variants related to children and adolescents' varied responses to obesity interventions remained unclear. (Source: Clinical Nutrition)
Source: Clinical Nutrition - November 27, 2023 Category: Nutrition Authors: Jing Chen, Wu-Cai Xiao, Jia-Jun Zhao, Rui Shan, Melanie Heitkamp, Xiao-Rui Zhang, Zheng Liu Tags: Meta-analyses Source Type: research

The association between human milk fatty acid composition in mothers with an elevated body mass index and infant growth changes
This study explored whether maternal weight status and breastfeeding type influence human milk FA composition and infant anthropometry during the first six months of life. (Source: Clinical Nutrition)
Source: Clinical Nutrition - November 26, 2023 Category: Nutrition Authors: Man-Chin Hua, Hui-Min Su, Tsung-Chieh Yao, Sui-Ling Liao, Ming-Han Tsai, Kuan-Wen Su, Li ‐Chen Chen, Shen-Hao Lai, Chih-Yung Chiu, Kuo-Wei Yeh, Jing-Long Huang Tags: Original article Source Type: research

Editorial Board
(Source: Clinical Nutrition)
Source: Clinical Nutrition - November 24, 2023 Category: Nutrition Source Type: research

Altered gut microbiome associated with metabolic-associated fatty liver disease in Chinese children
Limited studies have investigated the association between gut microbiota and metabolic dysfunction-associated fatty liver disease (MAFLD) because of its association with metabolic dysfunction in children and adolescents. We aimed to identify differences in gut microbiota composition and diversity between children with MAFLD and healthy counterparts. (Source: Clinical Nutrition)
Source: Clinical Nutrition - November 24, 2023 Category: Nutrition Authors: Jing Ji, Jiahong Sun, Juan Li, Jintang Xie, Bo Xi, Min Zhao Tags: Original article Source Type: research

Response to Letter to the Editor Clinical Nutrition
(Source: Clinical Nutrition)
Source: Clinical Nutrition - November 24, 2023 Category: Nutrition Authors: Arthur R.H. van Zanten, Pierre Singer Tags: Letter to the Editor Source Type: research