Aluminum and Other Chemical Elements in Parenteral Nutrition Components and All-in-One Admixtures
Parenteral nutrition (PN) can lead to high or even toxic exposure to aluminum (Al). We aimed to quantify concentrations of Al and other chemical elements of all-in-one (AIO) PN admixtures for adults prepared from commercial multichamber bags (Olimel ® 5.7%, Omegaflex® special, SmofKabiven®, all with and without electrolytes) and vitamin and trace element additives over a 48-hour period. Secondly, we determined the level of Al contamination resulting from admixing and infusion set use. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 18, 2023 Category: Nutrition Authors: Katja A. Sch önenberger, Christoph Saxer, Peter J. Neyer, Valentina V. Huwiler, Emilie Reber, Angelika Hammerer-Lercher, Zeno Stanga, Stefan Mühlebach Tags: Original article Source Type: research
Individualised energy and protein targets achieved during intensive care admission are associated with lower mortality in mechanically ventilated COVID-19 patients: the COFEED-19 study
This study explores the association between energy and protein intake and 90-day mortality in invasively mechanically ventilated COVID-19 patients, utilizing fat-free mass (FFM) and actual body weight (ABW) for nutritional requirements. Furthermore, the study investigates the occurrence of gastrointestinal (GI) intolerance in critically ill COVID-19 patients in relation to their nutritional intake and survival. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 17, 2023 Category: Nutrition Authors: Max Melchers, Anoek Jacqueline Hubertine Hermans, Suzanne Belia Hulsen, Imre Willemijn Kehinde Kouw, Arthur Raymond Hubert van Zanten Tags: Original article Source Type: research
The effect of overweight or obesity on osteoporosis: A systematic review and meta-analysis
Osteoporosis and obesity are closely related, and the relationships between different types of obesity and osteoporosis are inconsistent. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 17, 2023 Category: Nutrition Authors: Yupeng Liu, Yi Liu, Yufeng Huang, Siyu Le, Huinan Jiang, Binye Ruan, Xuemei Ao, Xudong Shi, Xiaoyi Fu, Shuran Wang Tags: Original article Source Type: research
A prospective study to assess the impact of a novel CFTR therapy combination on body composition in patients with cystic fibrosis with F508del mutation.
Malnutrition is a prevalent condition in Cystic Fibrosis (CF) and can result in worsening of pulmonary function and other comorbidities. Cystic fibrosis transmembrane regulator (CFTR) modulator therapies are improving the CF-related care and outcomes. Body Mass Index (BMI) is the most commonly used parameter to assess nutritional status, albeit it is a very unspecific indicator. Hence, current guidelines recommend body composition analysis as a part of nutritional assessment. The aim of our study was to evaluate the impact of elexacaftor-tezacaftor-ivacaftor (ELX/TEZ/IVA) treatment on body composition and respiratory funct...
Source: Clinical Nutrition - October 17, 2023 Category: Nutrition Authors: Carolina Knott-Torcal, Fernando Sebasti án-Valles, Rosa María Girón Moreno, José Carlos Martín- Adán, Jessica Jiménez-Díaz, Mónica Marazuela, Nuria Sánchez de la Blanca, Raúl Fernández-Contreras, Alfonso Arranz-Martín Tags: Original article Source Type: research
Crosstalk within peripheral blood mononuclear cells mediates anti-inflammatory effects of n-3 PUFA-rich lipid emulsions in parenteral nutrition
In this study, we compare the effect on inflammation of the commonly used lipid emulsions Omegaven (n-3-rich) and Intralipid (n-6-rich) in human peripheral blood mononuclear cells (PBMCs). (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 17, 2023 Category: Nutrition Authors: Paulina Wawrzyniak, Barbara Hubeli, Marcin Wawrzyniak, Nazek Noureddine, Asa Walberg, Sylvie Scharl, Matthias Turina, Michael Scharl, Michael Zaugg, Stefanie D. Kr ämer, Gerhard Rogler, Martin Hersberger Tags: Original article Source Type: research
Different Computed Tomography Parameters for Defining Myosteatosis in Patients with Advanced Non-Small Cell Lung Cancer
Myosteatosis, excess muscle fat infiltration, is a novel prognostic factor in cancer patients. To define myosteatosis, skeletal muscle radiodensity (SMD) is most commonly used, while intramuscular adipose tissue (IMAT) is newly introduced. We aimed to compare SMD-defined and IMAT-defined myosteatosis for predicting overall survival (OS) in patients with advanced non-small cell lung cancer (NSCLC) and to explore whether patients with both low SMD and high IMAT had a shorter OS than patients with low SMD or high IMAT alone. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 16, 2023 Category: Nutrition Authors: Wenyi Zhang, Jing Tang, Huiyu Tang, Lingling Xie, Jing Wang, Jinhui Wu, Ming Yang Tags: Original article Source Type: research
Human milk miRNAs associate to maternal dietary nutrients, milk microbiota, infant gut microbiota and growth
Maternal diet influences the milk composition, yet little information is available on the impact of maternal diet on milk miRNAs expression. Further, the association of milk miRNAs to maternal diet and milk microbiota is not explored. In addition, the role of milk miRNAs on the infant gut microbiota, infant growth and development has not been investigated. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 16, 2023 Category: Nutrition Authors: Laxmi Yeruva, Bharat Kumar Mulakala, Dhivyaa Rajasundaram, Sonia Gonzalez, Raul Cabrera-Rubio, Cecilia Martinez-Costa, Maria Carmen Collado Tags: Original article Source Type: research
Omega-3 fatty acids supplementation improves early-stage diabetic nephropathy and subclinical atherosclerosis in pediatric patients with type 1 diabetes: A randomized controlled trial
Numerous studies have evaluated the beneficial effects of omega-3 fatty acids on inflammatory, autoimmune and renal diseases. However, data about the effects of omega-3 fatty acids on diabetic kidney disease in type 1 diabetes mellitus (T1DM) are lacking. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 12, 2023 Category: Nutrition Authors: Nancy Samir Elbarbary, Eman Abdel Rahman Ismail, Sarah Abdelaal Mohamed Tags: Randomized Control Trials Source Type: research
The impact of prolonged fasting on 24h energy metabolism and its 24h rhythmicity in healthy, lean males: A randomized cross-over trial
Human energy expenditure and substrate oxidation are under circadian control and food intake is a time cue for the human biological clock, leading to 24h feeding –fasting cycles in energy and substrate metabolism. In recent years, (intermittent) fasting protocols have also become popular to improve metabolic health. Here, we aimed to investigate the impact of food intake on the 24h patterns of energy metabolism as well as to provide data on the timeline of changes in energy metabolism that occur upon an extended period of fasting. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 11, 2023 Category: Nutrition Authors: Charlotte Andriessen, Daniel Doligkeit, Esther Moonen-Kornips, Marco Mensink, Matthijs K.C. Hesselink, Joris Hoeks, Patrick Schrauwen Tags: Original article Source Type: research
The impact of prolonged fasting on 24h energy metabolism in healthy, lean males: a randomized cross-over trial
Human energy expenditure and substrate oxidation are under circadian control and food intake is a time cue for the human biological clock, leading to 24h feeding-fasting cycles in energy and substrate metabolism. In recent years, (intermittent) fasting protocols have also become popular to improve metabolic health. Here, we aimed to investigate the impact of food intake on the 24h patterns of energy metabolism as well as to provide data on the timeline of changes in energy metabolism that occur upon an extended period of fasting. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 11, 2023 Category: Nutrition Authors: Charlotte Andriessen, Daniel Doligkeit, Esther Moonen-Kornips, Marco Mensink, Matthijs K.C. Hesselink, Joris Hoeks, Patrick Schrauwen Tags: Original article Source Type: research
The inflammatory potential of diet is associated with the risk of age-related eye diseases
Inflammation is involved in the pathogenesis of cataract, age-related macular degeneration (AMD), and possibly open-angle glaucoma (OAG). We assessed whether the inflammatory potential of diet (quantified using the dietary inflammatory index; DII) affects the incidence of these common blinding age-related eye diseases. Serum inflammation markers were investigated as possible mediators. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 11, 2023 Category: Nutrition Authors: Jo ëlle E. Vergroesen, Eric F. Thee, Tosca O.E. de Crom, Jessica C. Kiefte-de Jong, Magda A. Meester-Smoor, Trudy Voortman, Caroline C.W. Klaver, Wishal D. Ramdas Tags: Original article Source Type: research
Associations of predominant night-eating with plasma glycemic status and continuous glucose monitoring measures among pregnant women
To examine whether predominant night-eating, defined as more than 50% of total daily energy intake consumed between 1900-0659 hours, is associated with glycemic outcomes in pregnancy. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 11, 2023 Category: Nutrition Authors: See Ling Loy, Chee Wai Ku, Ruther Teo Zheng, Celeste Hong Fei Lim, Ting Yu Chang, Ling-Wei Chen, Yin Bun Cheung, Keith M. Godfrey, Kok Hian Tan, Mary Foong-Fong Chong, Jerry Kok Yen Chan, Ngee Lek, Fabian Yap Tags: Original article Source Type: research
A low-carbohydrate diet with different fatty acids' sources in the treatment of obesity: impact on insulin resistance and adipogenesis
The search for nutritional intervention strategies against obesity has grown, highlighting the low-carbohydrate diet model. However, little is known about the impact of the quality of fatty acids consumed in this diet. Thus, we aim to investigate the influence of fatty acid quality on dietary strategy on obesity. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 10, 2023 Category: Nutrition Authors: Aline B. Santamarina, La ís V. Mennitti, Esther A. de Souza, Leonardo M.de Souza Mesquita, Isaú H. Noronha, José Ronnie C. Vasconcelos, Carla M. Prado, Luciana P. Pisani Tags: Original article Source Type: research
Effect of arachidonic and docosahexaenoic acid supplementation on quality of growth in preterm infants: A secondary analysis of a randomized controlled trial
A balanced supply of arachidonic acid (ARA) and docosahexaenoic acid (DHA) may be crucial for quality of growth in preterm infants. This secondary analysis of a randomized controlled trial aimed to determine the effect of enhanced ARA and DHA supplementation on growth and body composition in infants born before 29 weeks of gestation. Furthermore, we aimed to study associations between human milk feeding, growth patterns and body composition. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 9, 2023 Category: Nutrition Authors: Madelaine Eloranta Rossholt, Marianne Bratlie, Kristina Wendel, Marlen Fossan Aas, Gunnthorunn Gunnarsdottir, Drude Fugelseth, Are Hugo Pripp, Magnus Domell öf, Ketil Størdal, Tom Stiris, Sissel Jennifer Moltu Tags: Original article Source Type: research
The associations of erythrocyte membrane polyunsaturated fatty acids with skeletal muscle loss: A prospective cohort study
This study investigated the longitudinal relationship between the concentrations of erythrocyte membrane PUFAs and age-related changes in skeletal muscle mass over an average 6.5 years of follow-up in a Chinese middle-aged and older adult population. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 6, 2023 Category: Nutrition Authors: Mengyang Su, Xuanrui Zhang, Wei Hu, Zhenxiao Yang, Danyu Chen, Yingdi Yang, Keliang Xie, Yuming Chen, Zheqing Zhang Tags: Original article Source Type: research
