Dynamic assessment of Prealbumin for nutrition support effectiveness in critically ill patients
Serum prealbumin is considered to be a sensitive predictor of clinical outcomes and a quality marker for nutrition support. However, its susceptibility to inflammation restricts its usage in critically ill patients according to current guidelines. We assessed the performance of the initial value of prealbumin and dynamic changes for predicting the ICU mortality and the effectiveness of nutrition support in critically ill patients. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 14, 2024 Category: Nutrition Authors: Emmanuel Pardo, Matthieu Jabaudon, Thomas Godet, Bruno Pereira, Dominique Morand, Emmanuel Futier, Gauthier Arpajou, Elena Le Cam, Marie-Pierre Bonnet, Jean-Michel Constantin Source Type: research

Real-world evidence of combined treatment of biologics and exclusive enteral nutrition in patients with ileum-dominant Crohn ’s Disease: a multicenter study
Although biologics were prescribed to achieve and maintain clinical remission of active Crohn ’s disease (CD), almost half of patients experienced a loss of response or intolerance. Here, we investigated the efficacy of combined treatment of biologics and 16-weeks exclusive enteral nutrition (EEN) in moderate-to-severe CD patients with small intestine lesions. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 14, 2024 Category: Nutrition Authors: Wei Wang, Anning Yin, Jing Wang, Jiao Li, Jingyun Cheng, Jian Kang, Yaqing Xu, Yueyue Lu, Yuanping Yang, Juan Su, Qian Zhou, Ya Liu, Zhishun Tang, Haixia Ren, Weiwei Li, Weiguo Dong, Baoping Yu, Ping An Source Type: research

The Association Between Wet Overactive Bladder and Consumption of Tea, Coffee, and Caffeine: Results from 2005-2018 National Health and Nutrition Examination Survey
Previous studies have reported an inconsistent relationship between overactive bladder (OAB) and the consumption of tea, coffee, and caffeine. Our study aims to determine these associations in a large and nationally representative adult sample. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 12, 2024 Category: Nutrition Authors: Fucai Tang, Jiahao Zhang, Ruiying Huang, Haobin Zhou, Ting Yan, Zhicheng Tang, Zhibiao Li, Zechao Lu, Shuqiang Huang, Zhaohui He Source Type: research

Optimal probiotic combinations for treating nonalcoholic fatty liver disease: A systematic review and network meta-analysis
Probiotic administration is a promising therapy for improving conditions in NAFLD patients. This network meta-analysis aimed to compare and estimate the relative effects of probiotic interventions and identify the optimal probiotic species for the treatment of NAFLD (Nonalcoholic fatty liver disease) patients. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 12, 2024 Category: Nutrition Authors: Yafang Yang, Ligang Yang, Jiale Wu, Jing Hu, Min Wan, Jindi Bie, Jiaxin Li, Da Pan, Guiju Sun, Chao Yang Source Type: research

Role of one-carbon nutrient intake and diabetes during pregnancy in children ’s growth and neurodevelopment: a 2-year follow-up study of a prospective cohort
This study aimed to determine how maternal 1C nutrient intake was associated with DNA methylation and further, development of children, as well as whether maternal GDM status modified the association in a prospective cohort. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 12, 2024 Category: Nutrition Authors: Isma ’il Kadam, Mudar Dalloul, Jeanette Hausser, Doron Vaday, Ella Gilboa, Liang Wang, Joan Hittelman, Lori Hoepner, Lawrence Fordjour, Pavani Chitamanni, Anjana Saxena, Xinyin Jiang Source Type: research

Serum trace elements during treatment in pancreatic cancer patients and their associations with cancer prognosis
In this study, we assessed serum trace element concentrations in patients with pancreatic cancer and compared the results to those of healthy controls and patients with chronic pancreatitis. We evaluated the association between trace element concentrations during cancer treatment and the risk of cancer progression and mortality in pancreatic cancer patients. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 12, 2024 Category: Nutrition Authors: Jee Ah Kim, Jong Kyun Lee, Soo-Youn Lee Source Type: research

Weight Loss Impacts Risky Decisions in Obesity
Risk decision making is shaped by individual psychological and metabolic state. Individuals with obesity show not only altered risk behavior, but also metabolic and psychological abnormalities. The aim of the present study was to investigate whether a substantial weight loss in individuals with severe obesity will 1) normalize their metabolic and psychological state and 2) will change their pattern of decision guidance. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 11, 2024 Category: Nutrition Authors: Beatrix Keweloh, Damiano Terenzi, Eva Froehlich, Carol Coricelli, Paula St ürmer, Nathalie Rohmann, Perdita Wietzke-Braun, Alexia Beckmann, Matthias Laudes, Soyoung Q. Park Source Type: research

Ambient ultraviolet-B radiation, supplements and other factors interact to impact vitamin D status differently depending on ethnicity: a cross-sectional study
Many determinants of vitamin D status have been well-described, yet supplementation guidelines largely follow a one-size-for-all model and deficiency remains common. We hypothesised that accounting accurately for ultraviolet-B (UVB) radiation and considering interactions could advance understanding of vitamin D status. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 11, 2024 Category: Nutrition Authors: Margaret M. Brennan, Jos van Geffen, Michiel van Weele, Lina Zgaga, Rasha Shraim Source Type: research

Maternal non-compliance with recommended folic acid supplement use alters global DNA methylation in cord blood of newborns: a cohort study
Prenatal folate exposure may alter epigenetic marks in the offspring. We aimed to evaluate associations between prenatal exposure to folic acid (FA) in preconception and in utero with cord blood DNA methylation in long interspersed nuclear element 1 (LINE-1) and Alu short interspersed nuclear elements (SINEs) as markers of global DNA methylation levels. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 11, 2024 Category: Nutrition Authors: Eva Morales, Mar ía Teresa Prieto-Sánchez, Jaime Mendiola, Ana Cutillas-Tolín, Evdochia Adoamnei, Desirée Valera-Gran, Carmen Martínez-Graciá, Marina Santaella-Pascual, Clara Suárez-Martinez, Jesús Vioque, María Jesús Castaños, Eva del Castillo Source Type: research

The role of the nutrition in malnourished cancer patients: revisiting an old dilemma
GLIM definition of malnutrition is recognised all over the world and, when is referring to cancer, it specifies that weight or muscle loss are associated with an inflammatory status. However, the real-world practice shows that GLIM definition cannot encompass all the wide and heterogenous clinical presentations of cancer patients with malnutrition, which involves many other drivers beyond inflammation. Moreover, placing an excessive emphasis on the inflammation can overshadow, in the clinical practice, the role of the nutritional support in malnourished cancer patients. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 9, 2024 Category: Nutrition Authors: Federico Bozzetti Source Type: research

Efficacy of dietary supplements on mortality and clinical outcomes in adults with sepsis and septic shock: a systematic review and network meta-analysis
The aim of this network meta-analysis (NMA) was to investigate the effects of different dietary supplements on the mortality and clinical status of adults with sepsis. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 9, 2024 Category: Nutrition Authors: Maryam Safabakhsh, Hossein Imani, Hossein Shahinfar, Masoud Mohammadpour, Pejman Rohani, Sakineh Shab-Bidar Source Type: research

Dose-dependent effects of enteral nutrition on the faecal microbiota and short chain fatty acids
Enteral nutrition (EN) involves replacing all or part of a person ’s habitual diet with a nutritional formula. The impact of varying doses of EN on the gut microbiome remains understudied. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 8, 2024 Category: Nutrition Authors: Aleksandra Jatkowska, Konstantinos Gkikas, Ben Nichols, Bryn Short, Vasiliki-Konstantina Rizou, Panagiotis Kapranos, Jennifer Klein Gunnewiek, Edelyn Christina, Vaios Svolos, Christopher Quince, Konstantinos Gerasimidis Source Type: research

The role of the aryl hydrocarbon receptor (AhR) in modulating intestinal ILC3s to optimise gut pathogen resistance in lupus and benefits of nutritional AhR ligands.
Dysbiosis is emerging as a potential trigger of systemic lupus erythematosus (SLE). Group 3 innate lymphoid cells (ILC3s) are recognised as key regulators of intestinal homeostasis. The aryl hydrocarbon receptor (AhR) is critical to intestinal ILC3 development and function. This mechanistic review aimed to investigate whether AhR activation of gut ILC3s facilitates IL-22-mediated antimicrobial peptide (AMP) production to enhance colonisation resistance and ameliorate SLE pathology associated with intestinal dysbiosis. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 8, 2024 Category: Nutrition Authors: Niamh Hanlon, Natalie Gillan, James Neil, Karin Seidler Source Type: research

β-hydroxybutyrate exposure restores mitochondrial function in skeletal muscle satellite cells of critically ill patients
This study aimed to elucidate the distinct metabolic effects of critical illness and β-OHB on satellite cells isolated from these patients. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 8, 2024 Category: Nutrition Authors: Lucie Genserov á, František Duška, Adéla Krajčová Source Type: research

Association of added sugar intake and its forms and sources with handgrip strength decline among middle-aged and older adults: A prospective cohort study
This study aimed to investigate the association between added sugar intake and longitudinal changes in handgrip strength among middle-aged and elderly Chinese adults. (Source: Clinical Nutrition)
Source: Clinical Nutrition - April 4, 2024 Category: Nutrition Authors: Lin Zhu, Yeqing Gu, Jianguo Li, Shuna Yu, Jinhan Wang, Hongmei Wu, Ge Meng, Xuena Wang, Qing Zhang, Li Liu, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Kun Song, Qiang Liu, Kaijun Niu Tags: Original article Source Type: research