Sodium-glucose co-transporter 2 inhibitors and Sarcopenia: A Controversy that must be Solved
Diabetes mellitus is a risk factor for muscle loss and sarcopenia. Sodium-glucose co-transporter 2 inhibitors (SGLT2i) or “gliflozins” are one of the newest anti-hyperglycemic drugs. They reduce blood glucose levels by inhibiting renal glucose reabsorption in the early proximal convoluted tubule. Various randomized trials showed that SGLT2i have cardio-protective and reno-protective action. SGLT2i also affect body composition. They usually decrease body fat percentage, visceral and subcutaneous adipose tissue. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 5, 2023 Category: Nutrition Authors: Baris Afsar, Rengin Elsurer Afsar Tags: Narrative Review Source Type: research
Development and Validation of a Nomogram for Predicting Enteral Feeding Intolerance in Critically ill Patients (NOFI): Mixed retrospective and prospective cohort study
Developing and validating a clinical prediction nomogram of enteral feeding intolerance (NOFI) in critically ill patients. So as to help clinicians implement pre-intervention for patients with high risk of enteral feeding intolerance (FI), formulate individualized feeding strategies, and reduce the probability of FI occurrence. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 5, 2023 Category: Nutrition Authors: Youquan Wang, Yanhua Li, Huimei Wang, Hongxiang Li, Yuting Li, Liying Zhang, Chaoyang Zhang, Meng Gao, Nan Zhang, Dong Zhang Tags: Original article Source Type: research
A nutritional supplement during preconception and pregnancy increases human milk vitamin D but not B-vitamin concentrations
Optimal maternal vitamin status during pregnancy and lactation is essential to support maternal and infant health. For instance, vitamin D3 is involved in infant bone development, and B-vitamins are involved in various metabolic processes, including energy production. Through a double-blind randomised controlled trial, we investigated the effects of maternal supplementation from preconception throughout pregnancy until birth on human milk (HM) concentrations of vitamin D3 and B-vitamins. In addition, we aimed to characterise longitudinal changes in milk concentrations of these vitamins. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 4, 2023 Category: Nutrition Authors: Soo Min Han, Fang Huang, Jos é G.B. Derraik, Mark H. Vickers, Surabhi Devaraj, Karine Redeuil, Esther Campos-Giménez, Wei Wei Pang, Keith M. Godfrey, Shiao-Yng Chan, Sagar K. Thakkar, Wayne S. Cutfield, NiPPeR Study Group Tags: Randomized Control Trials Source Type: research
A micronutrient supplement during preconception and pregnancy increases human milk vitamin D but not B vitamin concentrations
Optimal maternal vitamin status during pregnancy and lactation is essential to support maternal and infant health. For instance, vitamin D3 is involved in infant bone development, and B vitamins are involved in various metabolic processes, including energy production. Through a double-blind randomized controlled trial, we investigated the effects of maternal supplementation from preconception throughout pregnancy until birth on human milk (HM) concentrations of vitamin D3 and B vitamins. In addition, we aimed to characterize longitudinal changes in milk concentrations of these vitamins. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 4, 2023 Category: Nutrition Authors: Soo Min Han, Fang Huang, Jos é G.B. Derraik, Mark H. Vickers, Surabhi Devaraj, Karine Redeuil, Esther Campos-Giménez, Wei Wei Pang, Keith M. Godfrey, Shiao-Yng Chan, Sagar K. Thakkar, Wayne S. Cutfield, The NiPPeR Study Group authors comprises Tags: Randomized Control Trials Source Type: research
Cost-utility analysis of teduglutide compared to standard care in weaning parenteral nutrition support in children with short bowel syndrome
This study aims to assess the incremental costs of teduglutide plus standard of care compared to standard of care alone in weaning PN support per quality-adjusted life year (QALY) gained in children with SBS. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 4, 2023 Category: Nutrition Authors: Daniela Gattini, Christina Belza, Raphael Kraus, Yaron Avitzur, Wendy J. Ungar, Paul W. Wales Tags: Original article Source Type: research
The 2023 Sir David Cuthbertson Lecture. A Fluid Journey: Experiments that Influenced Clinical Practice
This review summarises some of my work on fluid and electrolyte balance over the past 25 years and shows how the studies have influenced clinical practice. Missing pieces in the jigsaw will be filled in by summarising the work of others. The main theme is the chemical, physiological and clinical problems caused by inappropriate use of saline solutions including the hyperchloraemic acidosis caused by 0.9% saline. The importance of accurate and near-zero fluid balance in clinical practice is also emphasised. (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 2, 2023 Category: Nutrition Authors: Dileep N. Lobo Tags: Narrative Review Source Type: research
Associations Between Ultra-Processed Food Consumption and Kidney Function in an Older Adult Population with Metabolic Syndrome
This study aimed to cross-sectionally and longitudinally assess the association between UPF consumption and estimated-glomerular filtration rate (eGFR) based on Cystatin C (CysC). (Source: Clinical Nutrition)
Source: Clinical Nutrition - October 2, 2023 Category: Nutrition Authors: Cristina Valle-Hita, Andr és Díaz-López, Nerea Becerra-Tomás, Estefania Toledo, Isabel Cornejo-Pareja, Itziar Abete, Antoni Sureda, Maira Bes-Rastrollo, J. Alfredo Martínez, Francisco J. Tinahones, Josep A. Tur, Tany E. Garcidueñas-Fimbres, Francisc Tags: Original article Source Type: research
High protein provision of more than 1.2 g/kg improves muscle mass preservation and mortality in ICU patients: A systematic review and meta-analyses
ICU patients lose muscle mass rapidly and maintenance of muscle mass may contribute to improved survival rates and quality of life. Protein provision may be beneficial for preservation of muscle mass and other clinical outcomes, including survival. Current protein recommendations are expert-based and range from 1.2 to 2.0 g/kg. Thus, we performed a systematic review and meta-analysis on protein provision and all clinically relevant outcomes recorded in the available literature. (Source: Clinical Nutrition)
Source: Clinical Nutrition - September 29, 2023 Category: Nutrition Authors: Isabel M. van Ruijven, Jos é Abma, Anja H. Brunsveld-Reinders, Sandra N. Stapel, Faridi van Etten-Jamaludin, Yves Boirie, Rocco Barazzoni, Peter J.M. Weijs Tags: Meta-analyses Source Type: research
Evidence for the Protein Leverage Hypothesis in Preschool Children Prone to Obesity
The protein leverage hypothesis (PLH) proposed that strict regulation of protein intake drives energy overconsumption and obesity when diets are diluted by fat and/or carbohydrates. Evidence about the PLH has been found in adults, while studies in children are limited. Thus, we aimed to test the PLH by assessing the role of dietary protein on macronutrients, energy intake, and obesity risk using data from preschool children followed for 1.3 years. (Source: Clinical Nutrition)
Source: Clinical Nutrition - September 29, 2023 Category: Nutrition Authors: Hanyue Zhang, Alistair M. Senior, Christoph Saner, Nanna J. Olsen, Sofus C. Larsen, Stephen J. Simpson, David Raubenheimer, Berit L. Heitmann Tags: Original article Source Type: research
High protein provision of more than 1.2 g/kg improves muscle mass preservation and mortality in ICU patients: A systematic review and meta-analyses
ICU patients lose muscle mass rapidly and maintenance of muscle mass may contribute to improved survival rates and quality of life. Protein provision may be beneficial for preservation of muscle mass and other clinical outcomes, including survival. Current protein recommendations are expert-based and range from 1.2 to 2.0 g/kg. Thus, we performed a systematic review and meta-analysis on protein provision and all clinically relevant outcomes recorded in the available literature. (Source: Clinical Nutrition)
Source: Clinical Nutrition - September 29, 2023 Category: Nutrition Authors: Isabel M. van Ruijven, Jos é Abma, Anja H. Brunsveld-Reinders, Sandra N. Stapel, Faridi van Etten-Jamaludin, Yves Boirie, Rocco Barazzoni, Peter J.M. Weijs Tags: Meta-analyses Source Type: research
Reply – Letter to the editor (YCLNU-D-23-01653)
We thank Damani and colleagues for their interest and comments on our research regarding cystic fibrosis (CF)-related bone disease [1]. (Source: Clinical Nutrition)
Source: Clinical Nutrition - September 27, 2023 Category: Nutrition Authors: Halime Nayir Buyuksahin, Deniz Dogru, Alev Ozon Tags: Letter to the Editor Source Type: research
Reply- Letter to the editor (YCLNU-D-23-01653)
(Source: Clinical Nutrition)
Source: Clinical Nutrition - September 27, 2023 Category: Nutrition Authors: Halime Nayir Buyuksahin, Deniz Dogru, Alev Ozon Tags: Letter to the Editor Source Type: research
Walnut Consumption and Gut Microbial Metabolism: Results of an Exploratory Analysis from a Randomized, Crossover, Controlled-Feeding Study
The effect of walnut-related modulation of gut microbiota composition on microbiota functionality is unknown. The aim was to characterize the effect of a walnut-enriched diet (WD), compared to a fatty acid-matched diet devoid of walnuts (WFMD) and a diet where oleic acid replaces alpha-linolenic acid (ORAD), on bacterial gene expression. (Source: Clinical Nutrition)
Source: Clinical Nutrition - September 27, 2023 Category: Nutrition Authors: Kristina S. Petersen, Mansi Chandra, Jeremy R. Chen See, Jillian Leister, Fatemeh Jafari, Alyssa Tindall, Penny M. Kris-Etherton, Regina Lamendella Tags: Randomized Control Trials Source Type: research
Risk factors for catheter-related bloodstream infections associated with home parental nutrition in children with intestinal failure: a prospective cohort study
Catheter-related bloodstream infection (CRBSI) is the most common, potentially life-threatening complication of long-term parenteral nutrition (PN). We prospectively assessed the incidence and risk factors for CRBSI in children receiving long-term home PN (HPN) for intestinal failure (IF) in a single IF rehabilitation center. (Source: Clinical Nutrition)
Source: Clinical Nutrition - September 26, 2023 Category: Nutrition Authors: Maria Giovanna Puoti, Chiara D ’Eusebio, Hannah Littlechild, Emily King, Jutta Koeglmeier, Susan Hill Tags: Original article Source Type: research
Gut microbiota alterations induced by intensive chemotherapy in acute myeloid leukaemia patients are associated with gut barrier dysfunction and body weight loss
In this study, we investigated using a multi -omics strategy the changes in the gut microbiome induced by AML intense therapy and their association with gut barrier function and cachectic hallmarks. (Source: Clinical Nutrition)
Source: Clinical Nutrition - September 25, 2023 Category: Nutrition Authors: Sarah A. P ötgens, Sophie Lecop, Violaine Havelange, Fuyong Li, Audrey M. Neyrinck, Nathalie Neveux, Johan Maertens, Jens Walter, Hélène Schoemans, Nathalie M. Delzenne, Laure B. Bindels Tags: Original article Source Type: research
