Clinical Gastroenterology and Hepatology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Multilevel Interventions to Improve Colorectal Cancer Screening in an Urban Native American Community: A Pilot Randomized Clinical Trial
Native Americans have the highest burden of colorectal cancer (CRC) and the lowest rates of CRC screening across the United States.1 The disparities in CRC screening were made worse during the pandemic, creating an unmet need to implement evidence-based, multilevel interventions to improve CRC screening uptake. This can be achieved through an organized outreach program with identification of screen-eligible individuals using health records from the clinic; and a screening program with the following: (1) a mailed invitation, (2) a package of materials so patients can complete a fecal immunochemical test (FIT) kit from their...
Source: Clinical Gastroenterology and Hepatology - February 14, 2024 Category: Gastroenterology Authors: Aasma Shaukat, Jack Wolf, Kyle Ryder, Jennifer P. Wisdom, Timothy R. Church Tags: Research Letters Source Type: research

The Emerging Role of Glucagon-Like Peptide-1 Receptor Agonists for the Treatment of Metabolic- Dysfunction Associated Steatohepatitis
Metabolic dysfunction-associated steatotic liver disease (MASLD) affects one in three to four adult individuals and can progress to metabolic dysfunction-associated steatohepatitis (MASH) and cirrhosis. Insulin resistance plays a central role in MASLD/MASH pathophysiology with higher rates of MASLD (two in three) and MASH with fibrosis (one in five) in adults with obesity and diabetes. This review summarizes the role of glucagon-like peptide (GLP) -1 receptor agonists in treating MASLD/MASH. Although not approved by the Food and Drug Administration for the treatment of MASLD, this class of medication is available to treat ...
Source: Clinical Gastroenterology and Hepatology - February 14, 2024 Category: Gastroenterology Authors: Layla A. Abushamat, Pir Ahmad Shah, Robert H. Eckel, Stephen A. Harrison, Diana Barb Tags: Narrative Reviews Source Type: research

Sex Differences and Immunoglobulin E Should Not Be Forgotten in Type 1 Autoimmune Pancreatitis
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 14, 2024 Category: Gastroenterology Authors: Wen-Feng Xi, Xiao-Ying Bai, Ai-Ming Yang Tags: Letter to the Editor Source Type: research

Assessment and significance of histologic activity in Crohn disease
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 14, 2024 Category: Gastroenterology Authors: Alexandros D. Polydorides Tags: Editorial Source Type: research

Multi-level interventions to improve colorectal cancer screening in an urban Native American community: A pilot randomized clinical trial
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 14, 2024 Category: Gastroenterology Authors: Aasma Shaukat, Jack Wolf, Kyle Ryder, Jennifer P. Wisdom, Timothy R. Church Tags: Research Letter Source Type: research

Association between Vonoprazan and the risk of gastric cancer after Helicobacter pylori eradication
Potassium-competitive acid blockers (PCABs) have been increasingly used to treat upper gastrointestinal disorders, replacing proton pump inhibitors (PPIs). While PPIs are associated with an increased risk of gastric cancer (GC) after Helicobacter pylori (Hp) eradication, it is uncertain whether PCABs carry the same risk. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 12, 2024 Category: Gastroenterology Authors: Junya Arai, Atsushi Miyawaki, Tomonori Aoki, Ryota Niikura, Yoku Hayakawa, Hiroaki Fujiwara, Sozaburo Ihara, Mitsuhiro Fujishiro, Masato Kasuga Source Type: research

Hypercholesterolemia is associated with dysregulation of lipid metabolism and poor prognosis in primary biliary cholangitis
In this study, we aimed to investigate the prognostic value of baseline total cholesterol (TC) levels in PBC and characterized the lipid metabolism. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 12, 2024 Category: Gastroenterology Authors: Linhua Zheng, Siyuan Tian, Chunmei Yang, Bo Li, Gui Jia, Yansheng Liu, Ruiqing Sun, Xiufang Wang, Juan Deng, Miao Zhang, Lina Cui, Changcun Guo, Xinmin Zhou, Patrick S.C. Leung, Christopher L. Bowlus, M. Eric Gershwin, Yulong Shang, Ying Han Source Type: research

Dissecting Geographical and Racial Disparities in H.  pylori Infection Rates: Screening and Eradication Strategies in the U.S.
We read with interest the paper by Shah et  al1 describing the geographic variation of Helicobacter pylori positivity in the United States, using a large sample of adults in the Veterans Health Administration. H pylori infection rates were more than 40% in the South, including Texas and Alabama, but fell lower than 25% in the West and North east. Several points deserve attention. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 10, 2024 Category: Gastroenterology Authors: Yasutoshi Shiratori, Naoki Ishii, Anthony Kalloo Tags: Letters to the Editor Source Type: research

Reply
We appreciate the interest of Fouad and coworkers in our study regarding the prevalence of steatotic liver disease (SLD) in the United States.1 Our research is in line with the revised nomenclature to categorize SLD subtypes. In their recent letter to the editor, Fouad et  al2 express concerns about the newly adapted nomenclature, particularly in the context of mixed etiologies contributing to SLD. They suggest that the previously proposed nomenclature, specifically metabolic-associated fatty liver disease (MAFLD), might be superior in certain scenarios. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 10, 2024 Category: Gastroenterology Authors: Markos Kalligeros, Eleftherios Mylonakis, Mazen Noureddin Tags: Letters to the Editor Source Type: research

Steatotic Liver Disease: Advancing Science and Patient Care Beyond Traditions
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 10, 2024 Category: Gastroenterology Authors: Markos Kalligeros, Eleftherios Mylonakis, Mazen Noureddin Tags: Letter to the Editor Source Type: research

Dissecting Geographical and Racial Disparities in H. pylori Infection Rates: Screening and Eradication Strategies in the U.S.
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 10, 2024 Category: Gastroenterology Authors: Yasutoshi Shiratori, Naoki Ishii, Anthony Kalloo Tags: Letter to the Editor Source Type: research

Glucagon-Like Peptide-1 Receptor Agonists in Patients With Cirrhosis: Answering the Unanswered Questions?
Nonalcoholic fatty liver disease, now termed metabolic dysfunction-associated steatotic liver disease (MASLD),1 continues to be a growing public health issue, with cirrhosis-related mortality increasing at an alarming pace.2 Many studies have researched the use of glucagon-like peptide-1 receptor agonists (GLP1-RA) in patients with MASLD/metabolic dysfunction-associated steatohepatitis with demonstrable effects on reducing liver fat and lowering cardiovascular events.3 In a recent phase 2 trial in patients with metabolic dysfunction-associated steatohepatitis compensated cirrhosis, semaglutide did not significantly improve...
Source: Clinical Gastroenterology and Hepatology - February 9, 2024 Category: Gastroenterology Authors: Sara Mahgoub, Philip N. Newsome Tags: Editorial Source Type: research

From ChatGPT to GutGPT: Enhancing AI for Personalized Health Care
We recently read with great interest the recent study by Kerbage et  al,1 which accessed the accuracy of Chat Generative Pre-trained Transformer (ChatGPT) in addressing queries related to prevalent gastrointestinal diseases. The study revealed that ChatGPT demonstrated an 84% accuracy rate in responding to issues concerning inflammatory bowel disease, irritable bow el syndrome, colonoscopy, and colorectal cancer screening. This outcome bolsters the potential of ChatGPT as a physician educational tool, particularly in the realm of gut health care. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 9, 2024 Category: Gastroenterology Authors: Qingzhou Kong, Yueyue Li, Yanqing Li Tags: Letters to the Editor Source Type: research

From ChatGPT to GutGPT: Enhancing AI for Personalized Healthcare
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 9, 2024 Category: Gastroenterology Authors: Qingzhou Kong, Yueyue Li, Yanqing Li Tags: Letter to the Editor Source Type: research

Glucagon-like peptide-1 receptor agonists in patients with cirrhosis – answering the unanswered questions?
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 9, 2024 Category: Gastroenterology Authors: Sara Mahgoub, Philip N. Newsome Tags: Editorial Source Type: research