Syphilitic Proctitis With Clinical Features of Lymphoma
A 34-year-old man presented with left lower quadrant pain, tenesmus, occasional blood in stool, and malaise. A computed tomography scan revealed rectal wall thickening and enlarged pelvic lymph nodes (Figure A). A palpable mass was found during digital rectal examination. Colonoscopy showed a 1.5-cm ulcerated mass in the rectum, clinically suspicious for lymphoma (Figure B). (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 25, 2020 Category: Gastroenterology Authors: Taylor Bronson, Amir Behdad, Maryam K. Pezhouh Tags: IMAGE OF THE MONTH Source Type: research

Syphilitic Proctitis Clinically Mimicking Lymphoma
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 25, 2020 Category: Gastroenterology Authors: Taylor Bronson, Amir Behdad, Maryam K. Pezhouh Tags: Image of the Month Source Type: research

Organo-axial Gastric Volvulus
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 25, 2020 Category: Gastroenterology Authors: Adnan Aman Khan, Ahsan Ullah Khan, Justin Thomas Kupec Tags: Image of the Month Source Type: research

Peak Concentrations of Ustekinumab After Intravenous Induction Therapy Identify Patients With Crohn ’s Disease Likely to Achieve Endoscopic and Biochemical Remission
Little is known about the relationship between ustekinumab exposure during the first 2 weeks of treatment and outcomes of patients with Crohn ’s disease (CD). We investigated the relationship between serum concentrations of ustekinumab during the first 2 weeks of treatment and endoscopic and biochemical remission in patients with CD. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 25, 2020 Category: Gastroenterology Authors: Jurij Han žel, Jurij Zdovc, Tina Kurent, Nejc Sever, Katarina Javornik, Katja Tuta, Matic Koželj, Nataša Smrekar, Gregor Novak, Borut Štabuc, Erwin Dreesen, Debby Thomas, Tomaž Vovk, Iztok Grabnar, David Drobne Source Type: research

Rome IV Functional Gastrointestinal Disorders and Health Impairment in Subjects With Hypermobility Spectrum Disorders or Hypermobile Ehlers-Danlos Syndrome
Individuals with hypermobility spectrum disorder or hypermobile Ehlers-Danlos Syndrome (HSD/hEDS) are increasingly encountered by gastroenterologists and pose complex clinical challenges. Uncontrolled studies have found functional gastrointestinal disorders (FGIDs) to be common in patients with HSD/hEDS. Some patients have somatic symptoms (medically unexplained symptoms) that might affect FGIDs. We performed a case –control study to determine the prevalence of and factors associated with Rome IV FGIDs in subjects with HSD/hEDS compared with age- and sex- matched population-based controls. (Source: Clinical Gastroent...
Source: Clinical Gastroenterology and Hepatology - February 25, 2020 Category: Gastroenterology Authors: Ching Y. Lam, Olafur S. Palsson, William E. Whitehead, Ami D. Sperber, Hans Tornblom, Magnus Simren, Imran Aziz Source Type: research

Effectiveness of Ustekinumab Dose Escalation in Patients with Crohn ’s Disease
A subset of patients with Crohn ’s disease (CD) do not respond to ustekinumab at the standard dose of 90 mg every 8 weeks. Little is known about the efficacy of shortening the interval between doses. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 25, 2020 Category: Gastroenterology Authors: Jacob E. Ollech, Inessa Normatov, Noam Peleg, Jingzhou Wang, Shivani A. Patel, Victoria Rai, Yangtian Yi, Jorie Singer, Sushila R. Dalal, Atsushi Sakuraba, Russell D. Cohen, David T. Rubin, Joel Pekow Source Type: research

Biopsies From Ascending and Descending Colon are Sufficient for Diagnosis of Microscopic Colitis
Lymphocytic and collagenous colitis are types of microscopic colitis (MC) that commonly cause chronic watery diarrhea, but there are no macroscopic features of MC that can be detected during colonoscopy. Endoscopists therefore often collect multiple random colonic biopsies, potentially over sampling, increasing times of colonoscopy and slide review. We sought to identify sites from which biopsies could be taken and analyzed to identify patients with MC with a high level of sensitivity and determine the appropriate number of biopsies to take at these sites. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 25, 2020 Category: Gastroenterology Authors: Boris Virine, Nilesh Chande, David K. Driman Source Type: research

Prevalence and Clinical Significance of Portal Vein Thrombosis in Patients with Cirrhosis and Acute Decompensation
Portal vein thrombosis (PVT) is a common and serious complication in patients with cirrhosis. However, little is known about PVT in patients with cirrhosis and acute decompensation (AD). We investigated the prevalence and clinical significance of PVT in nonmalignant patients with cirrhosis and AD. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 25, 2020 Category: Gastroenterology Authors: Yan Zhang, Bao-yan Xu, Xian-bo Wang, Xin Zheng, Yan Huang, Jinjun Chen, Zhong-ji Meng, Yan-hang Gao, Zhi-ping Qian, Feng Liu, Xiao-bo Lu, Yu Shi, Jia Shang, Hai Li, Shao-yang Wang, Shan Yin, Shu-ning Sun, Yi-Xin Hou, Yan Xiong, Jun Chen, Bei-ling Li, Qing Source Type: research

Effects of Apremilast, an Oral Inhibitor of Phosphodiesterase 4, in a Randomized Trial of Patients with Active Ulcerative Colitis
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 25, 2020 Category: Gastroenterology Authors: Radhika Nittala, Ayaskanta Singh Source Type: research

Longitudinal Change in Thyroid-stimulating Hormone and Risk of Nonalcoholic Fatty Liver Disease
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 25, 2020 Category: Gastroenterology Authors: Goh Eun Chung, Donghee Kim, Min-Sun Kwak, Jeong Yoon Yim, Aijaz Ahmed, Joo Sung Kim Source Type: research

Risk factors of diverticulitis with special reference to inflammation
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 25, 2020 Category: Gastroenterology Authors: Tomoyuki Kawada Source Type: research

10 things every gastroenterologist should know about anti-reflux surgery!
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 25, 2020 Category: Gastroenterology Authors: Steven Park, Russell Weg, Vivek Kaul Source Type: research

Use of Total Underwater Colonoscopy to Navigate Endoscopic Challenges
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 25, 2020 Category: Gastroenterology Authors: Joseph C. Anderson Source Type: research

Is the Combination of Pharmacokinetic and Pharmacodynamic Monitoring of Infliximab-Treated Patients the Way Forward?
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 21, 2020 Category: Gastroenterology Authors: Nat ália Sousa Freitas Queiroz, Aline Charabaty Source Type: research

Systems-based strategies to consider treatment costs in clinical practice
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 21, 2020 Category: Gastroenterology Authors: Eric D. Shah, Corey A. Siegel Source Type: research

Undesirable Long-Term Outcome of Entecavir Therapy in Chronic Hepatitis B With Cirrhosis
The large study of Hou et  al1 is interesting and has provided important information on nucleos(t)ide analogue (Nuc) therapy up to 10 years in chronic hepatitis B virus (HBV) infection. The authors are to be commended for conducting such a well-designed study, with stringent definitions of clinical outcome events (COE), to confirm the long-term efficacy and safety of entecavir (ETV) therapy in chronic HBV infection. However, some important data of this study were not utilized for additional or further analyses and discussion. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Yun-Fan Liaw Tags: Letter to the Editor Source Type: research

Differences in Incidence and Mortality Trends of Colorectal Cancer Worldwide Based on Sex, Age, and Anatomic Location
We studied incidence and mortality trends of colorectal cancer (CRC) in 39 countries according to age, sex, and anatomic location (colon vs rectum). (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Martin C.S. Wong, Junjie Huang, Veeleah Lok, Jingxuan Wang, Franklin Fung, Hanyue Ding, Zhi-Jie Zheng Source Type: research

Trachealization in a Patient With Eosinophilic Esophagitis
A40-year-old man was referred for an esophagogastroduodenoscopy (EGD) for evaluation of intermittent nausea and vomiting of 2 months ’ duration. The patient denied obvious dysphagia but reported occasional difficulty with swallowing large pills since childhood. The EGD showed markedly prominent mucosal rings in the proximal esophagus (trachealization of esophagus) (Figure A), along with a stricture at 23 cm (Figure B) from the incisors that could not be traversed with a regular upper endoscope. The remainder of the examination was completed using an ultraslim scope and showed the presence of prominent rings in the di...
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Swathi Paleti, Joshua A. Hanson, Tarun Rustagi Tags: Electronic Image of the Month Source Type: research

Multiple Cycles of Granulocyte Colony-Stimulating Factor Increase Survival Times of Patients With Decompensated Cirrhosis in a Randomized Trial
There is controversy regarding the inclusion of granulocyte colony stimulating factor (G-CSF) in the treatment of decompensated cirrhosis. Previous studies tested only a single cycle of G-CSF administration or were underpowered to detect changes in survival time. We performed an adequately powered study to determine whether multiple cycles of G-CSF increased the survival of patients 1 year after the start of therapy. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Arka De, Sunita Kumari, Akash Singh, Amritjyot Kaur, Rattiram Sharma, Ashish Bhalla, Navneet Sharma, Naveen Kalra, Virendra Singh Source Type: research

Reply
We appreciate Oungpasuk et  al’s reply to our manuscript, which used a large, nationally representative sample of the U.S. population to demonstrate that chronic diarrhea and constipation are more common in depressed individuals.1 (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Sarah Ballou Tags: Letter to the Editor Source Type: research

Intussusception due to intestinal melanoma
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Hideaki Kinugasa, Fuminori Teraishi, Hiroyuki Okada Tags: Image of the Month Source Type: research

“Starry Sky” on Liver MRCP: Multiple Biliary Dilatation with Cyst Formation
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Bin Zhang, Jiasheng Cao, Xiujun Cai Tags: Image of the Month Source Type: research

Multiple Cycles of Granulocyte Colony Stimulating Factor Increase Survival Times of Patients With Decompensated Cirrhosis in a Randomized Trial
There is controversy over inclusion of granulocyte colony stimulating factor (G-CSF) in treatment of decompensated cirrhosis. Previous studies tested only a single cycle of G-CSF administration or were underpowered to detect changes in survival time. We performed an adequately powered study to determine whether multiple cycles of G-CSF increase survival of patients 1 year after the start of therapy. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Arka De, Sunita Kumari, Akash Singh, Amritjyot Kaur, Rattiram Sharma, Ashish Bhalla, Navneet Sharma, Naveen Kalra, Virendra Singh Source Type: research

Tyrosine Kinase Inhibitor-induced Colitis as A Rare Cause of Bloody Diarrhea
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Ye Ji Jung, Jae Joon Han, Chang Kyun Lee Tags: Image of the Month Source Type: research

Reply to Ms. Oungpasuk et al
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Sarah Ballou Source Type: research

Trachealization of Esophagus: Eosinophilic Esophagitis
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Swathi Paleti, Joshua A. Hanson, Tarun Rustagi Tags: Image of the Month Source Type: research

Differences in Incidence and Mortality Trends of Colorectal Cancer, Worldwide, Based on Sex, Age, and Anatomic Location
We studied incidence and mortality trends of colorectal cancer (CRC) in 39 countries according to age, sex, and anatomical location (colon vs rectum). (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Martin CS. Wong, Junjie Huang, Veeleah Lok, Jingxuan Wang, Franklin Fung, Hanyue Ding, Zhi-Jie Zheng Source Type: research

Effects of Colesevelam on Bowel Symptoms, Biomarkers, and Colonic Mucosal Gene Expression in Patients with Bile Acid Diarrhea in a Randomized Trial
Approximately one-third of patients with IBS-diarrhea (IBS-D) have increased bile acid (BA) synthesis or excretion. An open-label study showed benefits of colesevelam on bowel functions, consistent with luminal BA sequestration by colesevelam. We compared the effects of colesevelam vs placebo on symptoms and gene expression patterns in the sigmoid colon mucosa in patients with BA diarrhea associated with IBS-D. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Priya Vijayvargiya, Michael Camilleri, Paula Carlson, Asha Nair, Sara Linker Nord, Michael Ryks, Deborah Rhoten, Duane Burton, Irene Busciglio, Alan Lueke, W. Scott Harmsen, Leslie J. Donato Source Type: research

Long-term outcome of entecavir therapy in chronic hepatitis B with cirrhosis
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 20, 2020 Category: Gastroenterology Authors: Yun-Fan Liaw Source Type: research

Optimal Management in Preventing Mother-to-Infant Transmission of Hepatitis B: More Requires to Be Done
Dr Hou and colleagues1 proposed the management algorithm to interrupt mother-to-infant transmission of hepatitis B virus (HBV) in a recent issue of Clinical Gastroenterology and Hepatology. Although the article provides valuable information in preventing mother-to-infant transmission of HBV, I have some concerns about this article. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 19, 2020 Category: Gastroenterology Authors: Yi-Hua Zhou Tags: Letter to the Editor Source Type: research

Endoscopic Mucosal Resection Is a Dynamic Technique: Ongoing Refinement Continues to Improve Outcomes
We thank Jacques et  al1 for their insight on selecting the appropriate endoscopic resection modality for large colorectal laterally spreading lesions (LSLs). In response, we would like to make a few critical points. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 19, 2020 Category: Gastroenterology Authors: Michael J. Bourke, Neal Shahidi, Steven J. Heitman Tags: Letter to the Editor Source Type: research

Colorectal Cancer Screening Options
Colorectal cancer (CRC) typically occurs when precancerous polyps in the colon or in the rectum transform into cancer. Signs of cancer may include rectal bleeding, blood in the stool, or a change in bowel movements. With routine screening, CRC can be prevented or detected early. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 19, 2020 Category: Gastroenterology Tags: AGA Patient Education Section Source Type: research

Correction
Raffals LE, Nguyen GC, Rubin DT. Switching between biologics and biosimilars in inflammatory bowel disease. Clin Gastroenterol Hepatol 2019;17:818 –823. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 19, 2020 Category: Gastroenterology Tags: Correction Source Type: research

Correction
Zhang Y, Ding H, Chen T, Zhang X, Chen W-F, Li Q, Yao L, Korrapati P, Jin X-J, Zhang Y-X, Xu M-D, Zhou P-H. Outcomes of endoscopic submucosal dissection vs esophagectomy for T1 esophageal squamous cell carcinoma in a real-world cohort. Clin Gastroenterol Hepatol 2019;17:73-81. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 19, 2020 Category: Gastroenterology Tags: Correction Source Type: research

Correction
Feagan BG, Lasch K, Lissoos T, Cao C, Wojtowicz AM, Khalid JM, Colombel J-F. Rapid response to vedolizumab therapy in biologic-na ïve patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol 2019;17:130–138. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 19, 2020 Category: Gastroenterology Tags: Correction Source Type: research

Editorial Board
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 19, 2020 Category: Gastroenterology Source Type: research

Contents
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 19, 2020 Category: Gastroenterology Source Type: research

Elsewhere in the AGA Journals
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 19, 2020 Category: Gastroenterology Source Type: research

Information for Authors and Readers
Clinical Gastroenterology and Hepatology is the go-to resource on a broad spectrum of themes in clinical gastroenterology and hepatology. The official clinical practice journal of the AGA Institute brings you the best original research in the field with a unique combination of reviews, editorials, podcasts, video abstracts, and outcomes research —all supporting clinical practice. Articles on education, policy, and practice management highlight issues pertinent to clinicians. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 19, 2020 Category: Gastroenterology Source Type: research

Cover
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 19, 2020 Category: Gastroenterology Source Type: research

Diagnostic Accuracy of Noninvasive Tests to Detect Advanced Hepatic Fibrosis in Patients With Hepatitis C and End-Stage Renal Disease
For patients with liver disease from hepatitis C virus (HCV) infection complicated by end-stage renal disease (ESRD), it is important to assess liver fibrosis before kidney transplantation. We evaluated the accuracy of non-invasive tests to identify advanced hepatic fibrosis in patients with HCV and ESRD. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 18, 2020 Category: Gastroenterology Authors: Christopher J. Schmoyer, Dhiren Kumar, Gaurav Gupta, Richard K. Sterling Source Type: research

Diagnostic Accuracy of Non-Invasive Tests to Detect Advanced Hepatic Fibrosis in Patients With Hepatitis C and End-Stage Renal Disease
For patients with liver disease from hepatitis C virus (HCV) infection complicated by end-stage renal disease (ESRD), it is important to assess liver fibrosis before kidney transplantation. We evaluated the accuracy of non-invasive tests to identify advanced hepatic fibrosis in patients with HCV and ESRD. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 18, 2020 Category: Gastroenterology Authors: Christopher J. Schmoyer, Dhiren Kumar, Gaurav Gupta, Richard K. Sterling Source Type: research

Dietary Guidance From the International Organization for the Study of Inflammatory Bowel Diseases
Recent evidence points to a plausible role of diet and the microbiome in the pathogenesis of both Crohn ’s disease (CD) and Ulcerative Colitis (UC). Dietary therapies based on exclusion of table foods and replacement with nutritional formulas and/or a combination of nutritional formulas and specific table foods may induce remission in CD. In UC, specific dietary components have also been associated with flare of disease. While evidence of varying quality has identified potential harmful or beneficial dietary components, physicians and patients at the present time do not have guidance as to which foods are safe, may b...
Source: Clinical Gastroenterology and Hepatology - February 14, 2020 Category: Gastroenterology Authors: Arie Levine, Jonathan M. Rhodes, James O. Lindsay, Maria T. Abreu, Michael A. Kamm, Peter R. Gibson, Christoph Gasche, Mark S. Silverberg, Uma Mahadevan, Rotem Sigall Boneh, Eyton Wine, Oriana M. Damas, Graeme Syme, Gina L. Trakman, Chu Kion Yao, Stefanie Tags: Review Article Source Type: research

Effects of Tumor Necrosis Factor Antagonists in Patients With Primary Sclerosing Cholangitis
Few patients with primary sclerosing cholangitis (PSC) and inflammatory bowel diseases (IBD) are exposed to tumor necrosis factor (TNF) antagonists, because of the often mild symptoms of IBD. We assessed the effects of anti-TNF agents on liver function in patients with PSC and IBD and their efficacy in treatment of IBD. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 14, 2020 Category: Gastroenterology Authors: C.R.H. Hedin, G. Sado, N. Ndegwa, E. Lytvyak, A. Mason, A. Montano-Loza, A. Gerussi, F. Saffioti, D. Thorburn, E. Nilsson, G. Larsson, B.A. Moum, K.N. van Munster, C.Y. Ponsioen, C. Levy, N.F. Nogueira, C.L. Bowlus, N. Gotlieb, O. Shibolet, K.D. Lynch, R. Source Type: research

Comorbid Occurrence of Eosinophilic Esophagitis and Inflammatory Bowel Disease
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 14, 2020 Category: Gastroenterology Authors: Amnon Sonnenberg, Kevin O. Turner, Robert M. Genta Source Type: research

Near-complete disappearance of a giant focal nodular hyperplasia in the liver
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 14, 2020 Category: Gastroenterology Authors: Laxague Francisco, Ramallo Dario, McCormack Lucas Tags: Image of the Month Source Type: research

Dietary Guidance for Patients with Inflammatory Bowel Disease from the International Organization for the Study of Inflammatory Bowel Disease
Recent evidence points to a plausible role of diet and the microbiome in the pathogenesis of both Crohn ’s disease (CD) and Ulcerative Colitis (UC). Dietary therapies based on exclusion of table foods and replacement with nutritional formulas and/or a combination of nutritional formulas and specific table foods may induce remission in CD. In UC, specific dietary components have also been associated with flare of disease. While evidence of varying quality has identified potential harmful or beneficial dietary components, physicians and patients at the present time do not have guidance as to which foods are safe, may b...
Source: Clinical Gastroenterology and Hepatology - February 14, 2020 Category: Gastroenterology Authors: A. Levine, J.M. Rhodes, J.O. Lindsay, M.T. Abreu, M.A. Kamm, P.R. Gibson, C. Gasche, M.S. Silverberg, U. Mahadevan, R. Sigall Boneh, E. Wine, O.M. Damas, G. Syme, G.L. Trakman, C.K. Yao, S.I. Stockhamer, M.B. Hammami, L.C. Garces, G. Rogler, I.E. Koutroub Source Type: research

Combination Biologic Therapy in Inflammatory Bowel Disease: Experience from a Tertiary Care Center
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 14, 2020 Category: Gastroenterology Authors: Lukasz Kwapisz, Laura E. Raffals, David H. Bruining, Darrell S. Pardi, William J. Tremaine, Sunanda V. Kane, Konstantinos A. Papadakis, Nayantara Coelho-Prabhu, John B. Kisiel, Valerie Heron, William A. Faubion, Edward V. Loftus Source Type: research

What is Best Testing Ground for Clinical Evaluation of Single-use Duodenoscopes?
(Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 14, 2020 Category: Gastroenterology Authors: Vincenzo Cennamo, Stefano Landi, Marco Bassi, Stefania Ghersi, Emanuele Dabizzi Source Type: research

Model to Predict Progression of Liver Disease in Heavy Drinkers Is Useful Today and Supports the Future of Deep Learning
Alcohol-related liver disease (ALD) encompasses a broad spectrum of hepatic disorders including alcohol-related steatosis, alcoholic hepatitis, alcohol-related cirrhosis, and hepatocellular carcinoma. ALD is among the major causes of chronic liver disease and liver-related mortality worldwide, and is projected to be the leading cause of cirrhosis and indication for liver transplant listing in the coming decades.1 From the onset of heavy drinking, ALD gradually progresses through several stages of steatosis, steatohepatitis (ASH), fibrosis, and cirrhosis. (Source: Clinical Gastroenterology and Hepatology)
Source: Clinical Gastroenterology and Hepatology - February 13, 2020 Category: Gastroenterology Authors: Joseph C. Ahn, Vijay H. Shah Tags: Editorial Source Type: research