In-silico activity prediction and docking studies of some flavonol derivatives as anti-prostate cancer agents based on Monte Carlo optimization
The QSAR models are employed to predict the anti-proliferative activity of 81 derivatives of flavonol against prostate cancer using the Monte Carlo algorithm based on the index of ideality of correlation (IIC)... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 26, 2023 Category: Chemistry Authors: Faezeh Tajiani, Shahin Ahmadi, Shahram Lotfi, Parvin Kumar and Ali Almasirad Tags: Research Source Type: research
Synthetic strategy towards novel composite based on substituted pyrido[2,1-b][1,3,4]oxadiazine-dialdehyde chitosan conjugate with antimicrobial and anticancer activities
Synthesis of new compounds that have biological activity is an indispensible issue in order to deal with the drug resistant bacteria. This wok reports preparation of a novel composite based on substituted pyri... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 26, 2023 Category: Chemistry Authors: Reham A. Mohamed-Ezzat, Amr H. Hashem and Sawsan Dacrory Tags: Research Source Type: research
Green and white MEKC for determination of different anti-diabetic binary mixtures and their triple-combo pill
The work introduces green and white sustainable micellar electrokinetic chromatography (MEKC) procedure that could analyze therapeutically related drugs, empagliflozin (EMP), linagliptin (LIN) and metformin (M... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 25, 2023 Category: Chemistry Authors: Aya R. Ahmed, Mohamed A. Korany, Shereen M. Galal and Marwa A. A. Ragab Tags: Research Source Type: research
Adsorption of chromium from electroplating wastewater using activated carbon developed from water hyacinth
Industrial wastewater polluted with high concentrations of Cr is commonly discharged into water resources without proper treatment. This gives rise to the deterioration of water quality and imposes adverse eff... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 24, 2023 Category: Chemistry Authors: Zemene Worku, Samuel Tibebu, Jemal Fito Nure, Solomon Tibebu, Welldone Moyo, Abera Demeke Ambaye and Thabo T. I. Nkambule Tags: Research Source Type: research
Thermoplastic starch (TPS)-based composite films for wastewater treatment: synthesis and fundamental characterization
Modification of starch is a potential basic research aiming to improve its water barrier properties. The general purpose of this study is to manufacture cross-linked iodinated starch citrate (ISC) with a degre... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 24, 2023 Category: Chemistry Authors: Khadiga Mohamed Abas and Amina Abdel Meguid Attia Tags: Research Source Type: research
Green microwave quantum dots as luminescent probes for quantifying prucalopride: consistency of content and application to pharmacokinetic studies
Prucalopride (PCP) is a medication used for the management of constipation via regulating bowel motions. PCP is widely used all over the world. So, novel, rapid, and highly sensitive carbon dots N-CQDs were ob... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 19, 2023 Category: Chemistry Authors: Baher I. Salman Tags: Research Source Type: research
Discovery of a new potent oxindole multi-kinase inhibitor among a series of designed 3-alkenyl-oxindoles with ancillary carbonic anhydrase inhibitory activity as antiproliferative agents
An optimization strategy was adopted for designing and synthesizing new series of 2-oxindole conjugates. Selected compounds were evaluated for their antiproliferative effect in vitro against NCI-60 cell lines ... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 18, 2023 Category: Chemistry Authors: Rania S. M. Ismail, Ahmed M. El Kerdawy, Dalia H. Soliman, Hanan H. Georgey, Nagwa M. Abdel Gawad, Andrea Angeli and Claudiu T. Supuran Tags: Research Source Type: research
The application of Rumex abyssinicus based activated carbon for Brilliant Blue Reactive dye adsorption from aqueous solution
The environmental pollution and human health impacts associated with the discharge of massive dye-containing effluents necessitate a search for cost-effective treatment technology. Therefore, this research wor... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 18, 2023 Category: Chemistry Authors: Ashagrie Mengistu, Mikiyas Abewaa, Eba Adino, Ebisa Gizachew and Jemal Abdu Tags: Research Source Type: research
Hybridization of the effective pharmacophores for treatment of epilepsy: design, synthesis, in vivo anticonvulsant activity, and in silico studies of phenoxyphenyl-1,3,4-oxadiazole-thio-N-phenylacetamid hybrids
In this study, a new series of phenoxypheny... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 17, 2023 Category: Chemistry Authors: Azadeh Fakhrioliaei, Fahimeh Abedinifar, Pedram Salehi Darjani, Maryam Mohammadi-Khanaposhtani, Bagher Larijani, Nematollah Ahangar and Mohammad Mahdavi Tags: Research Source Type: research
A new strategy for the determination of the antidiabetics alogliptin, saxagliptin and vildagliptin using all-solid state potentiometric sensors
Herein, we report on the development of disposable screen printed carbon, nanostructure thin film Au/Pt and Pt/Pt all-solid state potentiometric sensors for some antidiabetic compounds called glibtins. The ele... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 16, 2023 Category: Chemistry Authors: Abeer Rashad Derar, Neven Ahmed and Emad Mohamed Hussien Tags: Research Source Type: research
Chromatographic reversed HPLC and TLC-densitometry methods for simultaneous determination of serdexmethylphenidate and dexmethylphenidate in presence of their degradation products —with computational assessment
Two Chromatographic methods have been established and optimized for simultaneous determination of serdexmethylphenidate (SER.DMP) and dexmethylphenidate (DMP) in the presence of their degradation products. The... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 15, 2023 Category: Chemistry Authors: Khadiga M. Kelani, Ahmed M. W. Nassar, Gamal A. Omran, Samir Morshedy, Ahmed Elsonbaty and Wael Talaat Tags: Research Source Type: research
Modification of conducting arylidene copolymers by formation of inclusion complexes: synthesis, characterization, and applications as highly corrosion inhibitors for mild steel
Modifying the metal surface is one solution to the industry ’s growing corrosion problem. Thus, via threading approach and insertion of copolymers (CoP5-7) containing polyarylidenes through the internal cavity ... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 15, 2023 Category: Chemistry Authors: Hemat M. Dardeer, Mohamed Abdel-Hakim, Kamal I. Aly and Marwa M. Sayed Tags: Research Source Type: research
Study of novel bidentate heterocyclic amine-based metal complexes and their biological activities: cytotoxicity and antimicrobial activity evaluation
Metallic antitumor drugs with heterocyclic ligands, such as novel AMI (amino methyl imidazole) complexes [Pd(AMI)Cl2](1), [Cu(AMI)L1](2), and [Cu(AMI)L2 ·2H2O](3) where L1 = oxalate and L2 = malonate, were synthes... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 15, 2023 Category: Chemistry Authors: Heba M. Fahmy, Fatma M. Abdel-Rahman, Anwar A. El-Sayed and Ahmed A. El-Sherif Tags: Research Source Type: research
Mathematical processing of absorption as green smart spectrophotometric methods for concurrent assay of hepatitis C antiviral drugs, Sofosbuvir and Simeprevir: application to combined pharmaceutical dosage forms and evaluation of the method greenness
The present work was developed to create three rapid, simple, eco-friendly, cheap spectrophotometric methods for concurrent assay of Sofosbuvir (SOF) and Simeprevir (SMV) in their pure, laboratory prepared mix... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 14, 2023 Category: Chemistry Authors: Sayed M. Derayea, Ahmed A. Abu-hassan, Ahmed A. Hamad, Walid E. Eltoukhi, Amal E. Hamad and Bassam Shaaban Mohammed Tags: Research Source Type: research
Cefoperazone rapidly and sensitive quantitative assessment via a validated RP-HPLC method for different dosage forms, in-use stability, and antimicrobial activities
Cefoperazone (Cfz) is a member of the third generation of parenteral cephalosporin antibiotics. It is used on a wide scale in prescribed antibiotic drugs as anti-infection, especially for Gram-negative and als... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 12, 2023 Category: Chemistry Authors: Mostafa F. Al-Hakkani, Nourhan Ahmed, Alaa A. Abbas and Mohammad H. A. Hassan Tags: Research Source Type: research
