Synthesis, biological evaluation, and computational studies of some novel quinazoline derivatives as anticancer agents
A series of quinazolinone derivatives (7a –7h) were synthesized as antiproliferative agents. All compounds, were synthesized through three steps method and structurally evaluated by FTIR, 1H-NMR, 13CNMR and Mass s... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 22, 2022 Category: Chemistry Authors: Leila Emami, Soghra Khabnadideh, Zahra Faghih, Farnoosh Farahvasi, Fatemeh Zonobi, Saman Zare Gheshlaghi, Shadi Daili, Ali Ebrahimi and Zeinab Faghih Tags: Research Source Type: research
Hydrophilic gold nanospheres: influence of alendronate, memantine, and tobramycin on morphostructural features
Turkevich gold nanospheres are the original nanospheres that have been modified over time. Its combination with targeting medications such as alendronate, memantine, and tobramycin will provide additional bene... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 22, 2022 Category: Chemistry Authors: Dina M. Eissa, Mokhtar M. Mabrouk, El Zeiny M. Ebeid and Mohamed A. Abdel Hamid Tags: Research Source Type: research
Synthesis and bioactivities evaluation of quinazolin-4(3H)-one derivatives as α-glucosidase inhibitors
The development of new antidiabetes agents is necessary to obtain optimal glycemic control and overcome its complications. Different quinazolin-4(3H)-one bearing phenoxy-acetamide derivatives (7a –r) were designed... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 15, 2022 Category: Chemistry Authors: Mahshid Moheb, Aida Iraji, Navid Dastyafteh, Minoo Khalili Ghomi, Milad Noori, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Fatemeh Rasekh, Bagher Larijani, Kamiar Zomorodian, Seyed Esmaeil Sadat-Ebrahimi and Mohammad Mahdavi Tags: Research Source Type: research
Nitrogen and sulfur-doped carbon quantum dots as fluorescent nanoprobes for spectrofluorimetric determination of olanzapine and diazepam in biological fluids and dosage forms: application to content uniformity testing
A validated, sensitive, and simple spectrofluorimetric method was developed for the analysis of two important CNS-acting drugs, olanzapine and diazepam, in their commercial tablets without the need for any pre... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 15, 2022 Category: Chemistry Authors: Galal Magdy, Noura Said, Ramadan A. El-Domany and Fathalla Belal Tags: Research Source Type: research
Bioactive isopimarane and 3,4-seco isopimarane diterpenoids from Isodon amethystoides
Isodon amethystoides (Lamiaceae) is a popular plant in folk medicine in the southern provinces of China. Our phytochemical investigation of the twigs and leaves of this plant led to the discovery of five new dite... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 14, 2022 Category: Chemistry Authors: Chenliang Zhao, Lang Zhou, Wenjian Xie, Lihan Zhao, Chiyuan Zhang, Kang He, Jianghai Ye, Jingjie Zhang, Lutai Pan, Juan Zou and Hongjie Zhang Tags: Research Source Type: research
