Electrochemically-selective electrode for quantification of dorzolamide in bulk drug substance and dosage form
Three smart carbon paste electrodes were fabricated to quantify dorzolamide hydrochloride DRZ, including conventional carbon paste I, modified carbon paste embedding Silica II, and modified carbon paste embedd... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - August 21, 2023 Category: Chemistry Authors: Mai M. Mora, Nahla S. Ismail, Hala E. Zaazaa and Shereen A. Boltia Tags: Research Source Type: research
Sustainable chromatographic quantitation of multi-antihypertensive medications: application on diverse combinations containing hydrochlorothiazide along with LC –MS/MS profiling of potential impurities: greenness and whiteness evaluation
Cardiovascular disorders are among the leading causes of death worldwide, especially hypertension, a silent killer syndrome requiring multiple drug therapy for appropriate management. Hydrochlorothiazide is an... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - August 19, 2023 Category: Chemistry Authors: Hoda M. Marzouk, Sara El-Hanboushy, Reem H. Obaydo, Yasmin M. Fayez, Mohamed Abdelkawy and Hayam M. Lotfy Tags: Research Source Type: research
Ionic liquid-based ultrasonic-assisted extraction coupled with HPLC to analyze isoquercitrin, trifolin and afzelin in Amygdalus persica L. flowers
This study aimed to establish a method for the simultaneous determination of isoquercitrin, trifolin and afzelin in A. persica flowers by high performance liquid chromatography (HPLC) with ionic liquid as extract... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - August 19, 2023 Category: Chemistry Authors: Wei Zhang, Zhenhua Yin, Qingfeng Guo, Lin Chen and Juanjuan Zhang Tags: Research Source Type: research
Sustainable eco-friendly ratio-based spectrophotometric and HPTLC-densitometric methods for simultaneous analysis of co-formulated anti-migraine drugs with overlapped spectra
Considering the green chemistry perspective and improving the environmental impact of quality control labs; two direct techniques with less hazardous solvents, less waste production and less energy consumption... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - August 17, 2023 Category: Chemistry Authors: Christine Maged El-Maraghy Tags: Research Source Type: research
Biosynthesis approach of zinc oxide nanoparticles for aqueous phosphorous removal: physicochemical properties and antibacterial activities
In this study, phosphorus (PO43 –-P) is removed from water samples using zinc oxide nanoparticles (ZnO NPs). These nanoparticles are produced easily, quickly, and sustainably using Onion extracts (Allium cepa) at ... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - August 16, 2023 Category: Chemistry Authors: Mona Khamis, Gamal A. Gouda and Adham M. Nagiub Tags: Research Source Type: research
Spectrum subtraction as a complementary method for six resolution techniques resolving overlapping spectra; application to multicomponent veterinary formulation with greenness and whiteness assessment
Mathematical filtration is an efficient tool to resolve the overlapping spectra of binary mixtures in zero or first order form. Herein, a comparative study was conducted between six economic, accurate and prec... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - August 15, 2023 Category: Chemistry Authors: Mahmoud G. Hagag, Ahmed M. Hemdan, Ahmed H. Nadim, Samah S. Abbas and Nesma M. Fahmy Tags: Research Source Type: research
Computational and theoretical chemistry of newly synthesized and characterized 2,2 ’-(5,5’-(1,4-phenylene)bis(1H-tetrazole-5,1-diyl))bis-N-acetamides
Energetic heterocycles, including pyridines, triazoles, and tetrazoles, exhibit greater density, heats of formation, and oxygen balance compared to their carbocyclic counterparts, making them a promising appro... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - August 14, 2023 Category: Chemistry Authors: Syeda Abida Ejaz, Aftab Farid, Seema Zargar, Pervaiz Ali Channar, Mubashir Aziz, Tanveer A. Wani, Hafiz Muhammad Attaullah, Rabail Ujhan, Arfa Tehzeeb, Aamer Saeed, Hafiz Saqib Ali and Mauricio F. Erben Tags: Research Source Type: research
Synthesis, DFT and molecular docking of novel (Z)-4-bromo-N-(4-butyl-3 (quinolin-3-yl)thiazol-2(3H)-ylidene)benzamide as elastase inhibitor
A new compound, C23H20BrN3OS, containing a quinoline-based iminothiazoline with a thiazoline ring, was synthesized and its crystal and molecular structures were analyzed through single crystal X-ray analysis. The... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - August 7, 2023 Category: Chemistry Authors: Muhammad Naeem Mustafa, Pervaiz Ali Channar, Syeda Abida Ejaz, Saira Afzal, Mubashir Aziz, Tahira Shamim, Aamer Saeed, Aisha A. Alsfouk, Rabail Ujan, Qamar Abbas and Tuncer H ökelek Tags: Research Source Type: research
LC –MS/MS separation and quantitation of ribavirin in chicken and comparison of different mass spectrometric platforms
A liquid chromatography –tandem mass spectrometry (LC–MS/MS) method was developed for the analysis of ribavirin in chicken. Samples was extracted with 0.1% formic acid and purified by Hypercarb cartridge prior ... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - August 7, 2023 Category: Chemistry Authors: Daokun Xu, Haolun Huang, Wenyan Hu, Xinmei Liu and Jun Yang Tags: Research Source Type: research
Development of green micellar HPLC –DAD method for simultaneous determination of some sulbactam combinations used in COVID-19 regimen
In a new attempt to separate some sulbactam combinations by green chemical method we came up with this research in which an ecofriendly, green, sustainable and selective method was established for separation o... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - August 5, 2023 Category: Chemistry Authors: Gamal H. Ragab, Hanaa M. Saleh, Nermeen M. Abdulla and Eman A. Bahgat Tags: Research Source Type: research
Hydro-organic mobile phase and factorial design application to attain green HPLC method for simultaneous assay of paracetamol and dantrolene sodium in combined capsules
The greenness of any analytical method has become a very important aspect of a good analytical method. However, most chromatographic methods depend on the usage of relatively large amounts of lethal and un-dec... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - August 2, 2023 Category: Chemistry Authors: Nora A. Abdallah, Manar M. Tolba, Amina M. El-Brashy, Fawzia A. Ibrahim and Mona E. Fathy Tags: Research Source Type: research
Acriflavine: an efficient green fluorescent probe for sensitive analysis of aceclofenac in pharmaceutical formulations
Acriflavine is a multipurpose drug that shows antibacterial, antiviral, antimalarial, and antifungal activities. The remarkable native fluorescence of acriflavine is exploited in analytical chemistry field as ... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - August 2, 2023 Category: Chemistry Authors: Amal A. El-Masry and Abdallah M. Zeid Tags: Research Source Type: research
Synthesis of phthalazine-based derivatives as selective anti-breast cancer agents through EGFR-mediated apoptosis: in vitro and in silico studies
The parent 2-(4-benzyl-1-oxophthalazin-2(1H)-yl)-acetohydrazide (4) has twenty-nine compounds. The starting material for their corresponding mono, dipeptides and reactions with active methylene compounds were pro... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 27, 2023 Category: Chemistry Authors: Sara M. Emam, Samir M. El Rayes, Ibrahim A. I. Ali, Hamdy A. Soliman and Mohamed S. Nafie Tags: Research Source Type: research
Ultra-high resolution X-ray structure of orthorhombic bovine pancreatic Ribonuclease A at 100K
The crystal structure of orthorhombic Bovine Pancreatic Ribonuclease A has been determined to 0.85 Å resolution using low temperature, 100 K, synchrotron X-ray data collected at 16000 keV (λ = 0.77 Å). This is... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 27, 2023 Category: Chemistry Authors: David R. Lisgarten, Rex A. Palmer, Jon B. Cooper, Claire E. Naylor, Rosemary C. Talbert, Brendan J. Howlin, John N. Lisgarten, Janez Konc, Shabir Najmudin and Carina M. C. Lobley Tags: Research Source Type: research
Adjusted green spectrophotometric determination of favipiravir and remdesivir in pharmaceutical form and spiked human plasma sample using different chemometric supported models
The environmentally friendly design of analytical methods is gaining interest in pharmaceutical analysis to reduce hazardous environmental impacts and improve safety and health conditions for analysts. The ada... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - July 27, 2023 Category: Chemistry Authors: Mohamed S. Imam, Ahmed H. Abdelazim, Sherif Ramzy, Afnan S. Batubara, Mohammed Gamal, Safwan Abdelhafiz and Abdallah M. Zeid Tags: Research Source Type: research
