Homogeneous liquid –liquid microextraction coupled with HPLC/DAD for determination of nirmatrelvir and ritonavir as COVID-19 combination therapy in human plasma
The study reports the development of a high-performance liquid chromatography/diode array detection method to measure the levels of nirmatrelvir and ritonavir in human plasma. These two antiviral medications a... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 24, 2023 Category: Chemistry Authors: Inas A. Abdallah, Sherin F. Hammad, Alaa Bedair and Fotouh R. Mansour Tags: Research Source Type: research
Logic-based modeling and drug repurposing for the prediction of novel therapeutic targets and combination regimens against E2F1-driven melanoma progression
Melanoma presents increasing prevalence and poor outcomes. Progression to aggressive stages is characterized by overexpression of the transcription factor E2F1 and activation of downstream prometastatic gene r... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 22, 2023 Category: Chemistry Authors: Nivedita Singh, Faiz M Khan, Lakshmi Bala, Julio Vera, Olaf Wolkenhauer, Brigitte P ützer, Stella Logotheti and Shailendra K. Gupta Tags: Research Source Type: research
Impact of carbonization conditions and adsorbate nature on the performance of activated carbon in water treatment
The physical and chemical structure of activated carbon (AC) varies with the carbonization temperature, activation process and time. The texture and toughness of the starting raw material also determine the mo... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 22, 2023 Category: Chemistry Authors: Ibrahim Karume, Simon Bbumba, Simon Tewolde, Is ’harq Z. T. Mukasa and Muhammad Ntale Tags: Review Source Type: research
Phenolic content, antioxidant and antimicrobial activities evaluation and relationship of commercial spices in the lebanese market
This study co... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 20, 2023 Category: Chemistry Authors: Youssef El Rayess, Lea Nehme, Chantal Ghanem, Marc El Beyrouthy, Carmen Sadaka, Samar Azzi-Achkouty, Nancy Nehme, Eda S önmez Gürer and Javad Sharifi-Rad Tags: Research Source Type: research
Facile solvent-free modified biochar for removal of mixed steroid hormones and heavy metals: isotherm and kinetic studies
Water contamination has become a global challenge to human survival. Non-biodegradable heavy metal cations and steroid hormones could accumulate in the human body and could result in serious health problems. I... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 20, 2023 Category: Chemistry Authors: Sefiu Olaitan Amusat, Temesgen Girma Kebede, Edward Ndumiso Nxumalo, Simiso Dube and Mathew Muzi Nindi Tags: Research Source Type: research
Synthesis, characterization, DNA binding interactions, DFT calculations, and Covid-19 molecular docking of novel bioactive copper(I) complexes developed via unexpected reduction of azo-hydrazo ligands
In this work, we focused on the 3rd goal of the sustainable development plan: achieving good health and supporting well-being. Two redox-active hydrazo ligands namely, phenylcarbonohydrazonoyldicyanide (PCHD) and... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 20, 2023 Category: Chemistry Authors: Eman Hassan Elsayed, Dhuha Al-Wahaib, Ali El-Dissouky Ali, Beshir A. Abd-El-Nabey and Hemmat A. Elbadawy Tags: Research Source Type: research
Environmentally friendly catalyst- and solvent-free synthesis of 2-anilino nicotinic acids derivatives as potential lead COX inhibitors
In this study, an environmentally friendly, solvent- and catalyst-free synthesis of 2-anilino nicotinic acids derivatives is reported. This operationally simple and green procedure was applied to a selection o... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 20, 2023 Category: Chemistry Authors: Mahsa Yarhorhosseini, Shahrzad Javanshir, Ahmad Shahir Sadr, Milad Noori, Navid Dastyafteh, Maryam Esmkhani, Aida Iraji and Mohammad Mahdavi Tags: Research Source Type: research
Thiazolopyrimidine derivatives as novel class of small molecule tyrosinase inhibitor
Tyrosinase, the rate-limiting enzyme of melanogenesis, plays a crucial role in hyperpigmentation. As a result, in this study, a novel class of thiazolopyrimidine derivatives was developed and synthesized as ty... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 19, 2023 Category: Chemistry Authors: Nastaran Ghasemi, Shahram Moradi, Aida Iraji and Mohammad Mahdavi Tags: Research Source Type: research
Cu (II)-catalyzed: synthesis of imidazole derivatives and evaluating their larvicidal, antimicrobial activities with DFT and molecular docking studies
This paper deals with the evaluation of novel imidazole molecules for their antimicrobial and larvicidal activities. A series of imidazole derivatives 1(a –f) and 2(a–e) were prepared by the Mannich base technique... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 18, 2023 Category: Chemistry Authors: Janani Mullaivendhan, Idhayadhulla Akbar, Mansour K. Gatasheh, Ashraf Atef Hatamleh, Anis Ahamed, Mohamed Hussain Syed Abuthakir and Raman Gurusamy Tags: Research Source Type: research
Efficient synthesis of 3-alkyl-2-(-1H-1,2,3-triazolyl)methyl)thio)-2,3-dihydroquinazolin-4(1H)-one derivative via multistep synthesis approach by novel Cu@Py-Oxa@SPION catalyst
In this pared, an efficient method is introduced for the synthesis of 3-alkyl-2-(((4-(2-oxopropyl)-1H-1,2,3-triazol-1-yl)alkyl)thio)-2,3-dihydroquinazolin-4(1H)-one derivatives. These novel products have both 1,2... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 14, 2023 Category: Chemistry Authors: Alireza Sherafati, Shahram Moradi and Mohammad Mahdavi Tags: Research Source Type: research
Design, spectral, molecular modeling, antimitotic, analytical and mechanism studies of phenyl isothiocyanate Girard's T derived metal complexes
The ligand N-{[(phenyl amino) thioxomethyl] hydrazino carbonyl methyl} trimethyl ammonium chloride (PTHAC) was prepared by the refluxing phenyl isothiocyanate and Girard-T (trimethyl ammonium-acethydrazide) in... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 12, 2023 Category: Chemistry Authors: Magda A. Akl, Nora A. El Mahdy, Zizi Elbadrawy, Abdelrahman S. El-Zeny and Mohsen M. Mostafa Tags: Research Source Type: research
Synthesis of hydroxyapatite/polyethylene glycol 6000 composites by novel dissolution/precipitation method: optimization of the adsorption process using a factorial design: DFT and molecular dynamic
In this work, we presented a synthesis of a composite based on HAp and PEG 6000 using a new method of synthesis dissolution precipitation to be applied for application of wastewater purification from toxic met... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 8, 2023 Category: Chemistry Authors: K. Azzaoui, S. Jodeh, E. Mejdoubi, B. Hammouti, M. Taleb, G. Ennabety, A. Berisha, M. Aaddouz, M. H. Youssouf, S. Shityakov, R. Sabbahi and M. Algarra Tags: Research Source Type: research
Green chromatographic methods for determination of co-formulated lidocaine hydrochloride and miconazole nitrate along with an endocrine disruptor preservative and potential impurity
Recently, green analytical chemistry (GAC) is a key issue towards the idea of sustainability, the analytical community is focused on developing analytical methods that incorporate green chemistry principles to... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 8, 2023 Category: Chemistry Authors: Esraa S. Ashour, Maha A. Hegazy, Amal M. Abou Al-Alamein, Ghada M. El-Sayed and Nermine S. Ghoniem Tags: Research Source Type: research
Developing an analytical method for quantification of trientine based on modified silver nanoparticles
In this study, the modified silver na... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 8, 2023 Category: Chemistry Authors: Mahsa Khodadadi and Ali Shayanfar Tags: Research Source Type: research
Removal of Pb(II) ions by cellulose modified-LaFeO3 sorbents from different biomasses
LaFeO3 perovskite is prepared by the cellulose-modified microwave-assisted citrate method using two different biomasses as a cellulose source; rice straw (RS) and banana peel (BP). The prepared samples are assign... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - November 4, 2023 Category: Chemistry Authors: Shimaa M. Ali, Mohamed A. El Mansop, Ahmed Galal, Soha M. Abd El Wahab, Wafaa M. T. El-Etr and Hanaa A. Zein El-Abdeen Tags: Research Source Type: research
