Synthesis, antileishmanial, antimalarial evaluation and molecular docking study of some hydrazine-coupled pyrazole derivatives
Pyrazole-bearing compounds are known for their diverse pharmacological effects including potent antileishmanial and antimalarial activities. Herein, some hydrazine-coupled pyrazoles were successfully synthesiz... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - January 8, 2024 Category: Chemistry Authors: Halefom Gebreselasse Berhe, Yihenew Simegniew Birhan, Botros Youssef Beshay, Huda Jawad Habib, Ariaya Hymete and Adnan Ahmed Bekhit Tags: Research Source Type: research
Green synthesis of silver nanoparticles and its environmental sensor ability to some heavy metals
This study marks a pioneering effort in utilizing Vachellia tortilis subsp. raddiana (Savi) Kyal.& Boatwr., (commonly known as acacia raddiana) leaves as both a reducing and stabilizing agent in the green “eco-f... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - January 6, 2024 Category: Chemistry Authors: Nesma H. Ibrahim, Gharib M. Taha, Noura Sh. A. Hagaggi and Marwa A. Moghazy Tags: Research Source Type: research
Tosyl-carrageenan/alginate composite adsorbent for removal of Pb2+ ions from aqueous solutions
The current study effectively designed novel cross-linked tosyl-carrageenan/alginate (Ts-Car/Alg) beads to remove Pb2+ ions from their aqueous solutions. To confirm the structure of the produced matrix, character... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - January 6, 2024 Category: Chemistry Authors: Mohamed Awed, Riham R. Mohamed, Kholod H. Kamal, Magdy W. Sabaa and Korany A. Ali Tags: Research Source Type: research
Synthesis and cytotoxic activity evaluation of novel imidazopyridine carbohydrazide derivatives
Two series of novel imidazo[1,2-a]pyridine-2-carbohydrazide derivatives have been designed, synthesized, and evaluated for cytotoxic activity. Target compounds were designed in two series: aryl hydrazone deriv... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - January 6, 2024 Category: Chemistry Authors: Maryam Firouzi, Zahra Haghighijoo, Masoomeh Eskandari, Maryam Mohabbati, Ramin Miri, Mohammad Hasan Jamei, Alireza Poustforoosh, Somayeh Nazari, Omidreza Firuzi, Mehdi Khoshneviszadeh and Najmeh Edraki Tags: Research Source Type: research
Targeting apoptosis; design, synthesis and biological evaluation of new benzoxazole and thiazole based derivatives
Several novel approaches to target Bcl-2 proteins and apoptotic pathways have been identified in recent years for the treatment of different types of cancer including colorectal cancer. However, no effective t... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - January 3, 2024 Category: Chemistry Authors: Sama W. Helmy, Mai I. Shahin, Nermin Samir, Deena S. Lasheen and Dalal A. Abou El Ella Tags: Research Source Type: research
Discovery of dual rho-associated protein kinase 1 (ROCK1)/apoptosis signal –regulating kinase 1 (ASK1) inhibitors as a novel approach for non-alcoholic steatohepatitis (NASH) treatment
In the current study we suggest a novel approach to curb non-alcoholic steatohepatitis (NASH) progression, and we suggest privileged scaffolds for the design of novel compounds for this aim. NASH is an advance... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - January 3, 2024 Category: Chemistry Authors: Yara A. Zaky, Mai W. Rashad, Marwa A. Zaater and Ahmed M. El Kerdawy Tags: Research Source Type: research
Synthesis, design, biological evaluation, and computational analysis of some novel uracil-azole derivatives as cytotoxic agents
In this study, a novel series of uraci... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - January 3, 2024 Category: Chemistry Authors: Leila Emami, Fateme Zare, Soghra Khabnadideh, Zahra Rezaei, Zahra Sabahi, Saman Zare Gheshlaghi, Marzieh Behrouz, Mina Emami, Zahra Ghobadi, Sedighe Madadelahi Ardekani, Fatemeh Barzegar, Ali Ebrahimi and Razieh Sabet Tags: Research Source Type: research
Olive industry liquid waste from trash to metal adsorbent for wastewater purification
The development of biobased polymeric materials for wastewater purification has become a demand due to the growing need for water free of hazardous metal ions for safe purposes. The organic components of the O... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - January 3, 2024 Category: Chemistry Authors: Isra Ishraydeh, Othman Hamed, Abdalhadi Deghles, Shehdeh Jodeh, Khalil Azzaoui, Abdelfattah Hasan, Mohyeddin Assali, Ataa Jaseer, Waseem Mansour, G ül Gülenay Hacıosmanoğlu, Zehra Semra Can and Manuel Algarra Tags: Research Source Type: research
A chemometric approach based on response surface methodology for optimization of antibiotic and organic dyes removal from water samples
In this study, the Fe3O4/rGO/Ag magnetic nanocomposite was synthesized and employed as an adsorbent for the removal of tetracycline (TC), crystal violet (CV), and methylene blue (MB) from water samples. The influ... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - January 3, 2024 Category: Chemistry Authors: Chou-Yi Hsu, Eyhab Ali, Haider Falih Shamikh Al-Saedi, Amjed Qasim Mohammed, Nadia Khalid Mustafa, Maysm Barzan Talib, Usama Kadem Radi, Montather F. Ramadan, Ahmed Ali Ami, Saeb Jasim Al-Shuwaili, Ahmed Alawadi, Ali Alsalamy and Leila Baharinikoo Tags: Research Source Type: research
Synthesis of 3-formyl-eudistomin U with anti-proliferation, anti-migration and apoptosis-promoting activities on melanoma cells
The discovery of new lead skeleton against melanoma are urgently needed due to its highly malignant and mortality. Herein, a new molecular entity (EU-5) derived from eudistomin U was synthesized with total yie... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - December 20, 2023 Category: Chemistry Authors: Jixiang Gao, Jinyi Liu, Tao Yu, Chenggong Xu, Hao Sun, Chunbo Lu, Wenjia Dan and Jiangkun Dai Tags: Research Source Type: research
Identification of isothiazolones analogues as potent bactericidal agents against antibiotic resistant CRE and MRSA strains
Carbapenem-resistant Enterobacterales (CRE) has emerged as a worldwide spread nosocomial superbug exhibiting antimicrobial resistance (AMR) to all current antibiotics, leaving limited options for treating its ... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - December 16, 2023 Category: Chemistry Authors: Wenbin Jin, Chen Xu, Ning Dong, Kaichao Chen, Die Zhang, Jinhua Ning, Yunbing Li, Guangfen Zhang, Jin Ke, Anguo Hou, Linyun Chen, Sheng Chen and Kin-Fai Chan Tags: Research Source Type: research
Smart green spectrophotometric assay of the ternary mixture of drotaverine, caffeine and paracetamol in their pharmaceutical dosage form
Three green and facile spectrophotometric methods were developed for the assay of Petro ® components; drotaverine HCl (DRT), caffeine (CAFF), and paracetamol (PAR). The three methods depend on measuring the absorb... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - December 13, 2023 Category: Chemistry Authors: Rana Ghonim, Manar M. Tolba, Fawzia Ibrahim and Mohamed I. El-Awady Tags: Research Source Type: research
Glycosides from the leaves of Fraxinus Hubeiensis
Fraxinus hubeiensis is a plant endemic to China and widely used as folk medicine to treat various diseases. However, its chemical constituents have never been reported sufficiently. Thus, the primary objective of... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - December 13, 2023 Category: Chemistry Authors: Xin-Yi Liu, Hong-Xia Tang, Wen-Bing Sheng, Qu-Jing Luo, Lin-Xi Mao, Yu-Pei Yang, Xiao-Zhou Guo, Qing-Lai Wu, Yu-Qing Jian, Wei Wang and Xu-Dong Zhou Tags: Research Source Type: research
The effect of nanoparticle coating on biological, chemical and biophysical parameters influencing radiosensitization in nanoparticle-aided radiation therapy
Nanoparticle-based composites have the potential to meet requirements for radiosensitization in both therapeutic and diagnostic applications. The radiosensitizing properties of nanoparticles could be reliant o... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - December 11, 2023 Category: Chemistry Authors: Elham Mansouri, Asghar Mesbahi, Hamed Hamishehkar, Soheila Montazersaheb, Vahid Hosseini and Saeed Rajabpour Tags: Review Source Type: research
Smartphone based colorimetric point-of-care sensor for abused drugs: case of baclofen determination in urine
As a GABA- β receptor agonist, the central muscle relaxant Baclofen (BAC) has a potential of abuse. Unfortunately, the sense of wellbeing and pleasure is obtained at very high BAC doses. This is associated with... (Source: Chemistry Central Journal)
Source: Chemistry Central Journal - December 10, 2023 Category: Chemistry Authors: Mariam O. Abd el-Aziz, Ahmed H. Nadim, Hany H. Monir, M. Nebsen and Sameh E. Younis Tags: Research Source Type: research
