An in silico model of the capturing of magnetic nanoparticles in tumour spheroids in the presence of flow
Biomed Microdevices. 2023 Nov 27;26(1):1. doi: 10.1007/s10544-023-00685-9.ABSTRACTOne of the main challenges in improving the efficacy of conventional chemotherapeutic drugs is that they do not reach the cancer cells at sufficiently high doses while at the same time affecting healthy tissue and causing significant side effects and suffering in cancer patients. To overcome this deficiency, magnetic nanoparticles as transporter systems have emerged as a promising approach to achieve more specific tumour targeting. Drug-loaded magnetic nanoparticles can be directed to the target tissue by applying an external magnetic field. ...
Source: Biomedical Microdevices - November 26, 2023 Category: Biomedical Engineering Authors: Barbara Wirthl Christina Janko Stefan Lyer Bernhard A Schrefler Christoph Alexiou Wolfgang A Wall Source Type: research

An in silico model of the capturing of magnetic nanoparticles in tumour spheroids in the presence of flow
Biomed Microdevices. 2023 Nov 27;26(1):1. doi: 10.1007/s10544-023-00685-9.ABSTRACTOne of the main challenges in improving the efficacy of conventional chemotherapeutic drugs is that they do not reach the cancer cells at sufficiently high doses while at the same time affecting healthy tissue and causing significant side effects and suffering in cancer patients. To overcome this deficiency, magnetic nanoparticles as transporter systems have emerged as a promising approach to achieve more specific tumour targeting. Drug-loaded magnetic nanoparticles can be directed to the target tissue by applying an external magnetic field. ...
Source: Biomedical Microdevices - November 26, 2023 Category: Biomedical Engineering Authors: Barbara Wirthl Christina Janko Stefan Lyer Bernhard A Schrefler Christoph Alexiou Wolfgang A Wall Source Type: research

An in silico model of the capturing of magnetic nanoparticles in tumour spheroids in the presence of flow
Biomed Microdevices. 2023 Nov 27;26(1):1. doi: 10.1007/s10544-023-00685-9.ABSTRACTOne of the main challenges in improving the efficacy of conventional chemotherapeutic drugs is that they do not reach the cancer cells at sufficiently high doses while at the same time affecting healthy tissue and causing significant side effects and suffering in cancer patients. To overcome this deficiency, magnetic nanoparticles as transporter systems have emerged as a promising approach to achieve more specific tumour targeting. Drug-loaded magnetic nanoparticles can be directed to the target tissue by applying an external magnetic field. ...
Source: Biomedical Microdevices - November 26, 2023 Category: Biomedical Engineering Authors: Barbara Wirthl Christina Janko Stefan Lyer Bernhard A Schrefler Christoph Alexiou Wolfgang A Wall Source Type: research

An in silico model of the capturing of magnetic nanoparticles in tumour spheroids in the presence of flow
Biomed Microdevices. 2023 Nov 27;26(1):1. doi: 10.1007/s10544-023-00685-9.ABSTRACTOne of the main challenges in improving the efficacy of conventional chemotherapeutic drugs is that they do not reach the cancer cells at sufficiently high doses while at the same time affecting healthy tissue and causing significant side effects and suffering in cancer patients. To overcome this deficiency, magnetic nanoparticles as transporter systems have emerged as a promising approach to achieve more specific tumour targeting. Drug-loaded magnetic nanoparticles can be directed to the target tissue by applying an external magnetic field. ...
Source: Biomedical Microdevices - November 26, 2023 Category: Biomedical Engineering Authors: Barbara Wirthl Christina Janko Stefan Lyer Bernhard A Schrefler Christoph Alexiou Wolfgang A Wall Source Type: research

An in silico model of the capturing of magnetic nanoparticles in tumour spheroids in the presence of flow
Biomed Microdevices. 2023 Nov 27;26(1):1. doi: 10.1007/s10544-023-00685-9.ABSTRACTOne of the main challenges in improving the efficacy of conventional chemotherapeutic drugs is that they do not reach the cancer cells at sufficiently high doses while at the same time affecting healthy tissue and causing significant side effects and suffering in cancer patients. To overcome this deficiency, magnetic nanoparticles as transporter systems have emerged as a promising approach to achieve more specific tumour targeting. Drug-loaded magnetic nanoparticles can be directed to the target tissue by applying an external magnetic field. ...
Source: Biomedical Microdevices - November 26, 2023 Category: Biomedical Engineering Authors: Barbara Wirthl Christina Janko Stefan Lyer Bernhard A Schrefler Christoph Alexiou Wolfgang A Wall Source Type: research

An in silico model of the capturing of magnetic nanoparticles in tumour spheroids in the presence of flow
Biomed Microdevices. 2023 Nov 27;26(1):1. doi: 10.1007/s10544-023-00685-9.ABSTRACTOne of the main challenges in improving the efficacy of conventional chemotherapeutic drugs is that they do not reach the cancer cells at sufficiently high doses while at the same time affecting healthy tissue and causing significant side effects and suffering in cancer patients. To overcome this deficiency, magnetic nanoparticles as transporter systems have emerged as a promising approach to achieve more specific tumour targeting. Drug-loaded magnetic nanoparticles can be directed to the target tissue by applying an external magnetic field. ...
Source: Biomedical Microdevices - November 26, 2023 Category: Biomedical Engineering Authors: Barbara Wirthl Christina Janko Stefan Lyer Bernhard A Schrefler Christoph Alexiou Wolfgang A Wall Source Type: research

An in silico model of the capturing of magnetic nanoparticles in tumour spheroids in the presence of flow
Biomed Microdevices. 2023 Nov 27;26(1):1. doi: 10.1007/s10544-023-00685-9.ABSTRACTOne of the main challenges in improving the efficacy of conventional chemotherapeutic drugs is that they do not reach the cancer cells at sufficiently high doses while at the same time affecting healthy tissue and causing significant side effects and suffering in cancer patients. To overcome this deficiency, magnetic nanoparticles as transporter systems have emerged as a promising approach to achieve more specific tumour targeting. Drug-loaded magnetic nanoparticles can be directed to the target tissue by applying an external magnetic field. ...
Source: Biomedical Microdevices - November 26, 2023 Category: Biomedical Engineering Authors: Barbara Wirthl Christina Janko Stefan Lyer Bernhard A Schrefler Christoph Alexiou Wolfgang A Wall Source Type: research

An in silico model of the capturing of magnetic nanoparticles in tumour spheroids in the presence of flow
Biomed Microdevices. 2023 Nov 27;26(1):1. doi: 10.1007/s10544-023-00685-9.ABSTRACTOne of the main challenges in improving the efficacy of conventional chemotherapeutic drugs is that they do not reach the cancer cells at sufficiently high doses while at the same time affecting healthy tissue and causing significant side effects and suffering in cancer patients. To overcome this deficiency, magnetic nanoparticles as transporter systems have emerged as a promising approach to achieve more specific tumour targeting. Drug-loaded magnetic nanoparticles can be directed to the target tissue by applying an external magnetic field. ...
Source: Biomedical Microdevices - November 26, 2023 Category: Biomedical Engineering Authors: Barbara Wirthl Christina Janko Stefan Lyer Bernhard A Schrefler Christoph Alexiou Wolfgang A Wall Source Type: research

An in silico model of the capturing of magnetic nanoparticles in tumour spheroids in the presence of flow
Biomed Microdevices. 2023 Nov 27;26(1):1. doi: 10.1007/s10544-023-00685-9.ABSTRACTOne of the main challenges in improving the efficacy of conventional chemotherapeutic drugs is that they do not reach the cancer cells at sufficiently high doses while at the same time affecting healthy tissue and causing significant side effects and suffering in cancer patients. To overcome this deficiency, magnetic nanoparticles as transporter systems have emerged as a promising approach to achieve more specific tumour targeting. Drug-loaded magnetic nanoparticles can be directed to the target tissue by applying an external magnetic field. ...
Source: Biomedical Microdevices - November 26, 2023 Category: Biomedical Engineering Authors: Barbara Wirthl Christina Janko Stefan Lyer Bernhard A Schrefler Christoph Alexiou Wolfgang A Wall Source Type: research

Cell phone microscopy enabled low-cost manufacturable colorimetric urine glucose test
Biomed Microdevices. 2023 Nov 6;25(4):43. doi: 10.1007/s10544-023-00682-y.ABSTRACTGlucose serves as a pivotal biomarker crucial for the monitoring and diagnosis of a spectrum of medical conditions, encompassing hypoglycemia, hyperglycemia, and diabetes, all of which may precipitate severe clinical manifestations in individuals. As a result, there is a growing demand within the medical domain for the development of rapid, cost-effective, and user-friendly diagnostic tools. In this research article, we introduce an innovative glucose sensor that relies on microfluidic devices meticulously crafted from disposable, medical-gra...
Source: Biomedical Microdevices - November 6, 2023 Category: Biomedical Engineering Authors: Zhuolun Meng Hassan Raji Muhammad Tayyab Mehdi Javanmard Source Type: research

Cell phone microscopy enabled low-cost manufacturable colorimetric urine glucose test
Biomed Microdevices. 2023 Nov 6;25(4):43. doi: 10.1007/s10544-023-00682-y.ABSTRACTGlucose serves as a pivotal biomarker crucial for the monitoring and diagnosis of a spectrum of medical conditions, encompassing hypoglycemia, hyperglycemia, and diabetes, all of which may precipitate severe clinical manifestations in individuals. As a result, there is a growing demand within the medical domain for the development of rapid, cost-effective, and user-friendly diagnostic tools. In this research article, we introduce an innovative glucose sensor that relies on microfluidic devices meticulously crafted from disposable, medical-gra...
Source: Biomedical Microdevices - November 6, 2023 Category: Biomedical Engineering Authors: Zhuolun Meng Hassan Raji Muhammad Tayyab Mehdi Javanmard Source Type: research

Cell phone microscopy enabled low-cost manufacturable colorimetric urine glucose test
Biomed Microdevices. 2023 Nov 6;25(4):43. doi: 10.1007/s10544-023-00682-y.ABSTRACTGlucose serves as a pivotal biomarker crucial for the monitoring and diagnosis of a spectrum of medical conditions, encompassing hypoglycemia, hyperglycemia, and diabetes, all of which may precipitate severe clinical manifestations in individuals. As a result, there is a growing demand within the medical domain for the development of rapid, cost-effective, and user-friendly diagnostic tools. In this research article, we introduce an innovative glucose sensor that relies on microfluidic devices meticulously crafted from disposable, medical-gra...
Source: Biomedical Microdevices - November 6, 2023 Category: Biomedical Engineering Authors: Zhuolun Meng Hassan Raji Muhammad Tayyab Mehdi Javanmard Source Type: research

Cell phone microscopy enabled low-cost manufacturable colorimetric urine glucose test
Biomed Microdevices. 2023 Nov 6;25(4):43. doi: 10.1007/s10544-023-00682-y.ABSTRACTGlucose serves as a pivotal biomarker crucial for the monitoring and diagnosis of a spectrum of medical conditions, encompassing hypoglycemia, hyperglycemia, and diabetes, all of which may precipitate severe clinical manifestations in individuals. As a result, there is a growing demand within the medical domain for the development of rapid, cost-effective, and user-friendly diagnostic tools. In this research article, we introduce an innovative glucose sensor that relies on microfluidic devices meticulously crafted from disposable, medical-gra...
Source: Biomedical Microdevices - November 6, 2023 Category: Biomedical Engineering Authors: Zhuolun Meng Hassan Raji Muhammad Tayyab Mehdi Javanmard Source Type: research

Cell phone microscopy enabled low-cost manufacturable colorimetric urine glucose test
Biomed Microdevices. 2023 Nov 6;25(4):43. doi: 10.1007/s10544-023-00682-y.ABSTRACTGlucose serves as a pivotal biomarker crucial for the monitoring and diagnosis of a spectrum of medical conditions, encompassing hypoglycemia, hyperglycemia, and diabetes, all of which may precipitate severe clinical manifestations in individuals. As a result, there is a growing demand within the medical domain for the development of rapid, cost-effective, and user-friendly diagnostic tools. In this research article, we introduce an innovative glucose sensor that relies on microfluidic devices meticulously crafted from disposable, medical-gra...
Source: Biomedical Microdevices - November 6, 2023 Category: Biomedical Engineering Authors: Zhuolun Meng Hassan Raji Muhammad Tayyab Mehdi Javanmard Source Type: research

Cell phone microscopy enabled low-cost manufacturable colorimetric urine glucose test
Biomed Microdevices. 2023 Nov 6;25(4):43. doi: 10.1007/s10544-023-00682-y.ABSTRACTGlucose serves as a pivotal biomarker crucial for the monitoring and diagnosis of a spectrum of medical conditions, encompassing hypoglycemia, hyperglycemia, and diabetes, all of which may precipitate severe clinical manifestations in individuals. As a result, there is a growing demand within the medical domain for the development of rapid, cost-effective, and user-friendly diagnostic tools. In this research article, we introduce an innovative glucose sensor that relies on microfluidic devices meticulously crafted from disposable, medical-gra...
Source: Biomedical Microdevices - November 6, 2023 Category: Biomedical Engineering Authors: Zhuolun Meng Hassan Raji Muhammad Tayyab Mehdi Javanmard Source Type: research