Multi-parameter surface plasmon resonance instrument for multiple nucleic acid quantitative detection
Biomed Microdevices. 2023 Jul 7;25(3):24. doi: 10.1007/s10544-023-00664-0.ABSTRACTMultiplex nucleic acid assays can simultaneously detect the characteristics of different target nucleic acids in complex mixtures and are used in disease diagnosis, environmental monitoring, and food safety. However, traditional nucleic acid amplification assays have limitations such as complicated operation, long detection time, unstable fluorescent labeling, and mutual interference of multiplex nucleic acids. We developed a real-time, rapid, and label-free surface plasmon resonance (SPR) instrument for multiplex nucleic acid detection. The ...
Source: Biomedical Microdevices - July 7, 2023 Category: Biomedical Engineering Authors: Huixiang Wang Honggang Wang Yafeng Huang Hao Zhang Yongdong Fu Zhenwei Yang Yuanyuan Chen Xianbo Qiu Duli Yu Lulu Zhang Source Type: research

Multi-parameter surface plasmon resonance instrument for multiple nucleic acid quantitative detection
Biomed Microdevices. 2023 Jul 7;25(3):24. doi: 10.1007/s10544-023-00664-0.ABSTRACTMultiplex nucleic acid assays can simultaneously detect the characteristics of different target nucleic acids in complex mixtures and are used in disease diagnosis, environmental monitoring, and food safety. However, traditional nucleic acid amplification assays have limitations such as complicated operation, long detection time, unstable fluorescent labeling, and mutual interference of multiplex nucleic acids. We developed a real-time, rapid, and label-free surface plasmon resonance (SPR) instrument for multiplex nucleic acid detection. The ...
Source: Biomedical Microdevices - July 7, 2023 Category: Biomedical Engineering Authors: Huixiang Wang Honggang Wang Yafeng Huang Hao Zhang Yongdong Fu Zhenwei Yang Yuanyuan Chen Xianbo Qiu Duli Yu Lulu Zhang Source Type: research

Multi-parameter surface plasmon resonance instrument for multiple nucleic acid quantitative detection
Biomed Microdevices. 2023 Jul 7;25(3):24. doi: 10.1007/s10544-023-00664-0.ABSTRACTMultiplex nucleic acid assays can simultaneously detect the characteristics of different target nucleic acids in complex mixtures and are used in disease diagnosis, environmental monitoring, and food safety. However, traditional nucleic acid amplification assays have limitations such as complicated operation, long detection time, unstable fluorescent labeling, and mutual interference of multiplex nucleic acids. We developed a real-time, rapid, and label-free surface plasmon resonance (SPR) instrument for multiplex nucleic acid detection. The ...
Source: Biomedical Microdevices - July 7, 2023 Category: Biomedical Engineering Authors: Huixiang Wang Honggang Wang Yafeng Huang Hao Zhang Yongdong Fu Zhenwei Yang Yuanyuan Chen Xianbo Qiu Duli Yu Lulu Zhang Source Type: research

Multi-parameter surface plasmon resonance instrument for multiple nucleic acid quantitative detection
Biomed Microdevices. 2023 Jul 7;25(3):24. doi: 10.1007/s10544-023-00664-0.ABSTRACTMultiplex nucleic acid assays can simultaneously detect the characteristics of different target nucleic acids in complex mixtures and are used in disease diagnosis, environmental monitoring, and food safety. However, traditional nucleic acid amplification assays have limitations such as complicated operation, long detection time, unstable fluorescent labeling, and mutual interference of multiplex nucleic acids. We developed a real-time, rapid, and label-free surface plasmon resonance (SPR) instrument for multiplex nucleic acid detection. The ...
Source: Biomedical Microdevices - July 7, 2023 Category: Biomedical Engineering Authors: Huixiang Wang Honggang Wang Yafeng Huang Hao Zhang Yongdong Fu Zhenwei Yang Yuanyuan Chen Xianbo Qiu Duli Yu Lulu Zhang Source Type: research

Multi-parameter surface plasmon resonance instrument for multiple nucleic acid quantitative detection
Biomed Microdevices. 2023 Jul 7;25(3):24. doi: 10.1007/s10544-023-00664-0.ABSTRACTMultiplex nucleic acid assays can simultaneously detect the characteristics of different target nucleic acids in complex mixtures and are used in disease diagnosis, environmental monitoring, and food safety. However, traditional nucleic acid amplification assays have limitations such as complicated operation, long detection time, unstable fluorescent labeling, and mutual interference of multiplex nucleic acids. We developed a real-time, rapid, and label-free surface plasmon resonance (SPR) instrument for multiplex nucleic acid detection. The ...
Source: Biomedical Microdevices - July 7, 2023 Category: Biomedical Engineering Authors: Huixiang Wang Honggang Wang Yafeng Huang Hao Zhang Yongdong Fu Zhenwei Yang Yuanyuan Chen Xianbo Qiu Duli Yu Lulu Zhang Source Type: research

Multi-parameter surface plasmon resonance instrument for multiple nucleic acid quantitative detection
Biomed Microdevices. 2023 Jul 7;25(3):24. doi: 10.1007/s10544-023-00664-0.ABSTRACTMultiplex nucleic acid assays can simultaneously detect the characteristics of different target nucleic acids in complex mixtures and are used in disease diagnosis, environmental monitoring, and food safety. However, traditional nucleic acid amplification assays have limitations such as complicated operation, long detection time, unstable fluorescent labeling, and mutual interference of multiplex nucleic acids. We developed a real-time, rapid, and label-free surface plasmon resonance (SPR) instrument for multiplex nucleic acid detection. The ...
Source: Biomedical Microdevices - July 7, 2023 Category: Biomedical Engineering Authors: Huixiang Wang Honggang Wang Yafeng Huang Hao Zhang Yongdong Fu Zhenwei Yang Yuanyuan Chen Xianbo Qiu Duli Yu Lulu Zhang Source Type: research

Multi-parameter surface plasmon resonance instrument for multiple nucleic acid quantitative detection
Biomed Microdevices. 2023 Jul 7;25(3):24. doi: 10.1007/s10544-023-00664-0.ABSTRACTMultiplex nucleic acid assays can simultaneously detect the characteristics of different target nucleic acids in complex mixtures and are used in disease diagnosis, environmental monitoring, and food safety. However, traditional nucleic acid amplification assays have limitations such as complicated operation, long detection time, unstable fluorescent labeling, and mutual interference of multiplex nucleic acids. We developed a real-time, rapid, and label-free surface plasmon resonance (SPR) instrument for multiplex nucleic acid detection. The ...
Source: Biomedical Microdevices - July 7, 2023 Category: Biomedical Engineering Authors: Huixiang Wang Honggang Wang Yafeng Huang Hao Zhang Yongdong Fu Zhenwei Yang Yuanyuan Chen Xianbo Qiu Duli Yu Lulu Zhang Source Type: research

Multi-parameter surface plasmon resonance instrument for multiple nucleic acid quantitative detection
Biomed Microdevices. 2023 Jul 7;25(3):24. doi: 10.1007/s10544-023-00664-0.ABSTRACTMultiplex nucleic acid assays can simultaneously detect the characteristics of different target nucleic acids in complex mixtures and are used in disease diagnosis, environmental monitoring, and food safety. However, traditional nucleic acid amplification assays have limitations such as complicated operation, long detection time, unstable fluorescent labeling, and mutual interference of multiplex nucleic acids. We developed a real-time, rapid, and label-free surface plasmon resonance (SPR) instrument for multiplex nucleic acid detection. The ...
Source: Biomedical Microdevices - July 7, 2023 Category: Biomedical Engineering Authors: Huixiang Wang Honggang Wang Yafeng Huang Hao Zhang Yongdong Fu Zhenwei Yang Yuanyuan Chen Xianbo Qiu Duli Yu Lulu Zhang Source Type: research

Multi-parameter surface plasmon resonance instrument for multiple nucleic acid quantitative detection
Biomed Microdevices. 2023 Jul 7;25(3):24. doi: 10.1007/s10544-023-00664-0.ABSTRACTMultiplex nucleic acid assays can simultaneously detect the characteristics of different target nucleic acids in complex mixtures and are used in disease diagnosis, environmental monitoring, and food safety. However, traditional nucleic acid amplification assays have limitations such as complicated operation, long detection time, unstable fluorescent labeling, and mutual interference of multiplex nucleic acids. We developed a real-time, rapid, and label-free surface plasmon resonance (SPR) instrument for multiplex nucleic acid detection. The ...
Source: Biomedical Microdevices - July 7, 2023 Category: Biomedical Engineering Authors: Huixiang Wang Honggang Wang Yafeng Huang Hao Zhang Yongdong Fu Zhenwei Yang Yuanyuan Chen Xianbo Qiu Duli Yu Lulu Zhang Source Type: research

Multi-parameter surface plasmon resonance instrument for multiple nucleic acid quantitative detection
Biomed Microdevices. 2023 Jul 7;25(3):24. doi: 10.1007/s10544-023-00664-0.ABSTRACTMultiplex nucleic acid assays can simultaneously detect the characteristics of different target nucleic acids in complex mixtures and are used in disease diagnosis, environmental monitoring, and food safety. However, traditional nucleic acid amplification assays have limitations such as complicated operation, long detection time, unstable fluorescent labeling, and mutual interference of multiplex nucleic acids. We developed a real-time, rapid, and label-free surface plasmon resonance (SPR) instrument for multiplex nucleic acid detection. The ...
Source: Biomedical Microdevices - July 7, 2023 Category: Biomedical Engineering Authors: Huixiang Wang Honggang Wang Yafeng Huang Hao Zhang Yongdong Fu Zhenwei Yang Yuanyuan Chen Xianbo Qiu Duli Yu Lulu Zhang Source Type: research

Rapid electrical impedance detection of sickle cell vaso-occlusion in microfluidic device
Biomed Microdevices. 2023 Jun 22;25(3):23. doi: 10.1007/s10544-023-00663-1.ABSTRACTSickle cell disease is characterized by painful vaso-occlusive crises, in which poorly deformable sickle cells play an important role in the complex vascular obstruction process. Existing techniques are mainly based on optical microscopy and video processing of sickle blood flow under normoxic condition, for measuring vaso-occlusion by a small fraction of dense sickle cells of intrinsic rigidity but not the vaso-occlusion by the rigid, sickled cells due to deoxygenation. Thus, these techniques are not suitable for rapid, point-of-care testin...
Source: Biomedical Microdevices - June 22, 2023 Category: Biomedical Engineering Authors: Yuhao Qiang Darryl Dieujuste Jia Liu Ofelia Alvarez E Du Source Type: research

Rapid electrical impedance detection of sickle cell vaso-occlusion in microfluidic device
Biomed Microdevices. 2023 Jun 22;25(3):23. doi: 10.1007/s10544-023-00663-1.ABSTRACTSickle cell disease is characterized by painful vaso-occlusive crises, in which poorly deformable sickle cells play an important role in the complex vascular obstruction process. Existing techniques are mainly based on optical microscopy and video processing of sickle blood flow under normoxic condition, for measuring vaso-occlusion by a small fraction of dense sickle cells of intrinsic rigidity but not the vaso-occlusion by the rigid, sickled cells due to deoxygenation. Thus, these techniques are not suitable for rapid, point-of-care testin...
Source: Biomedical Microdevices - June 22, 2023 Category: Biomedical Engineering Authors: Yuhao Qiang Darryl Dieujuste Jia Liu Ofelia Alvarez E Du Source Type: research

Rapid electrical impedance detection of sickle cell vaso-occlusion in microfluidic device
Biomed Microdevices. 2023 Jun 22;25(3):23. doi: 10.1007/s10544-023-00663-1.ABSTRACTSickle cell disease is characterized by painful vaso-occlusive crises, in which poorly deformable sickle cells play an important role in the complex vascular obstruction process. Existing techniques are mainly based on optical microscopy and video processing of sickle blood flow under normoxic condition, for measuring vaso-occlusion by a small fraction of dense sickle cells of intrinsic rigidity but not the vaso-occlusion by the rigid, sickled cells due to deoxygenation. Thus, these techniques are not suitable for rapid, point-of-care testin...
Source: Biomedical Microdevices - June 22, 2023 Category: Biomedical Engineering Authors: Yuhao Qiang Darryl Dieujuste Jia Liu Ofelia Alvarez E Du Source Type: research

Rapid electrical impedance detection of sickle cell vaso-occlusion in microfluidic device
Biomed Microdevices. 2023 Jun 22;25(3):23. doi: 10.1007/s10544-023-00663-1.ABSTRACTSickle cell disease is characterized by painful vaso-occlusive crises, in which poorly deformable sickle cells play an important role in the complex vascular obstruction process. Existing techniques are mainly based on optical microscopy and video processing of sickle blood flow under normoxic condition, for measuring vaso-occlusion by a small fraction of dense sickle cells of intrinsic rigidity but not the vaso-occlusion by the rigid, sickled cells due to deoxygenation. Thus, these techniques are not suitable for rapid, point-of-care testin...
Source: Biomedical Microdevices - June 22, 2023 Category: Biomedical Engineering Authors: Yuhao Qiang Darryl Dieujuste Jia Liu Ofelia Alvarez E Du Source Type: research

Rapid electrical impedance detection of sickle cell vaso-occlusion in microfluidic device
Biomed Microdevices. 2023 Jun 22;25(3):23. doi: 10.1007/s10544-023-00663-1.ABSTRACTSickle cell disease is characterized by painful vaso-occlusive crises, in which poorly deformable sickle cells play an important role in the complex vascular obstruction process. Existing techniques are mainly based on optical microscopy and video processing of sickle blood flow under normoxic condition, for measuring vaso-occlusion by a small fraction of dense sickle cells of intrinsic rigidity but not the vaso-occlusion by the rigid, sickled cells due to deoxygenation. Thus, these techniques are not suitable for rapid, point-of-care testin...
Source: Biomedical Microdevices - June 22, 2023 Category: Biomedical Engineering Authors: Yuhao Qiang Darryl Dieujuste Jia Liu Ofelia Alvarez E Du Source Type: research