High-aspect-ratio three-dimensional polymer and metallic microstructure microfabrication using two-photon polymerization
Biomed Microdevices. 2023 Jul 29;25(3):28. doi: 10.1007/s10544-023-00665-z.ABSTRACTCreating micrometer-resolution high-aspect-ratio three-dimensional (3D) structures remain very challenging despite significant microfabrication methods developed for microelectromechanical systems (MEMS). This is especially the case when such structures are desired to be metallic to support electronic applications. Here, we present a microfabrication process that combines two-photon-polymerization (2PP) printing to create a polymeric high-aspect-ratio three-dimensional structure and electroless metal plating that selectively electroplates on...
Source: Biomedical Microdevices - July 29, 2023 Category: Biomedical Engineering Authors: Ethan Vargas Can Huang Zhiyu Yan Harold White Jun Zou Arum Han Source Type: research
High-aspect-ratio three-dimensional polymer and metallic microstructure microfabrication using two-photon polymerization
Biomed Microdevices. 2023 Jul 29;25(3):28. doi: 10.1007/s10544-023-00665-z.ABSTRACTCreating micrometer-resolution high-aspect-ratio three-dimensional (3D) structures remain very challenging despite significant microfabrication methods developed for microelectromechanical systems (MEMS). This is especially the case when such structures are desired to be metallic to support electronic applications. Here, we present a microfabrication process that combines two-photon-polymerization (2PP) printing to create a polymeric high-aspect-ratio three-dimensional structure and electroless metal plating that selectively electroplates on...
Source: Biomedical Microdevices - July 29, 2023 Category: Biomedical Engineering Authors: Ethan Vargas Can Huang Zhiyu Yan Harold White Jun Zou Arum Han Source Type: research
High-aspect-ratio three-dimensional polymer and metallic microstructure microfabrication using two-photon polymerization
Biomed Microdevices. 2023 Jul 29;25(3):28. doi: 10.1007/s10544-023-00665-z.ABSTRACTCreating micrometer-resolution high-aspect-ratio three-dimensional (3D) structures remain very challenging despite significant microfabrication methods developed for microelectromechanical systems (MEMS). This is especially the case when such structures are desired to be metallic to support electronic applications. Here, we present a microfabrication process that combines two-photon-polymerization (2PP) printing to create a polymeric high-aspect-ratio three-dimensional structure and electroless metal plating that selectively electroplates on...
Source: Biomedical Microdevices - July 29, 2023 Category: Biomedical Engineering Authors: Ethan Vargas Can Huang Zhiyu Yan Harold White Jun Zou Arum Han Source Type: research
High-aspect-ratio three-dimensional polymer and metallic microstructure microfabrication using two-photon polymerization
Biomed Microdevices. 2023 Jul 29;25(3):28. doi: 10.1007/s10544-023-00665-z.ABSTRACTCreating micrometer-resolution high-aspect-ratio three-dimensional (3D) structures remain very challenging despite significant microfabrication methods developed for microelectromechanical systems (MEMS). This is especially the case when such structures are desired to be metallic to support electronic applications. Here, we present a microfabrication process that combines two-photon-polymerization (2PP) printing to create a polymeric high-aspect-ratio three-dimensional structure and electroless metal plating that selectively electroplates on...
Source: Biomedical Microdevices - July 29, 2023 Category: Biomedical Engineering Authors: Ethan Vargas Can Huang Zhiyu Yan Harold White Jun Zou Arum Han Source Type: research
High-aspect-ratio three-dimensional polymer and metallic microstructure microfabrication using two-photon polymerization
Biomed Microdevices. 2023 Jul 29;25(3):28. doi: 10.1007/s10544-023-00665-z.ABSTRACTCreating micrometer-resolution high-aspect-ratio three-dimensional (3D) structures remain very challenging despite significant microfabrication methods developed for microelectromechanical systems (MEMS). This is especially the case when such structures are desired to be metallic to support electronic applications. Here, we present a microfabrication process that combines two-photon-polymerization (2PP) printing to create a polymeric high-aspect-ratio three-dimensional structure and electroless metal plating that selectively electroplates on...
Source: Biomedical Microdevices - July 29, 2023 Category: Biomedical Engineering Authors: Ethan Vargas Can Huang Zhiyu Yan Harold White Jun Zou Arum Han Source Type: research
Biosensors; noninvasive method in detection of C-reactive protein (CRP)
Biomed Microdevices. 2023 Jul 27;25(3):27. doi: 10.1007/s10544-023-00666-y.ABSTRACTEarly diagnosis of C reactive protein (CRP) is critical to applying effective therapies for related diseases. Diagnostic technology in today's healthcare systems is mostly deployed in central laboratories, involves expensive and time-consuming processes, and is operated by specialized personnel. For example, the enzyme-linked immunosorbent assay (ELISA), considered the gold standard diagnostic method, is labor-intensive and requires complex procedures such as multiple washing and labeling steps. Due to these limitations of current diagnostic...
Source: Biomedical Microdevices - July 27, 2023 Category: Biomedical Engineering Authors: Hamidreza Hassanzadeh Khanmiri Fatemeh Yazdanfar Ahmad Mobed Fatemeh Rezamohammadi Mehrnoush Rahmani Tannaz Haghgouei Source Type: research
Biosensors; noninvasive method in detection of C-reactive protein (CRP)
Biomed Microdevices. 2023 Jul 27;25(3):27. doi: 10.1007/s10544-023-00666-y.ABSTRACTEarly diagnosis of C reactive protein (CRP) is critical to applying effective therapies for related diseases. Diagnostic technology in today's healthcare systems is mostly deployed in central laboratories, involves expensive and time-consuming processes, and is operated by specialized personnel. For example, the enzyme-linked immunosorbent assay (ELISA), considered the gold standard diagnostic method, is labor-intensive and requires complex procedures such as multiple washing and labeling steps. Due to these limitations of current diagnostic...
Source: Biomedical Microdevices - July 27, 2023 Category: Biomedical Engineering Authors: Hamidreza Hassanzadeh Khanmiri Fatemeh Yazdanfar Ahmad Mobed Fatemeh Rezamohammadi Mehrnoush Rahmani Tannaz Haghgouei Source Type: research
Biosensors; noninvasive method in detection of C-reactive protein (CRP)
Biomed Microdevices. 2023 Jul 27;25(3):27. doi: 10.1007/s10544-023-00666-y.ABSTRACTEarly diagnosis of C reactive protein (CRP) is critical to applying effective therapies for related diseases. Diagnostic technology in today's healthcare systems is mostly deployed in central laboratories, involves expensive and time-consuming processes, and is operated by specialized personnel. For example, the enzyme-linked immunosorbent assay (ELISA), considered the gold standard diagnostic method, is labor-intensive and requires complex procedures such as multiple washing and labeling steps. Due to these limitations of current diagnostic...
Source: Biomedical Microdevices - July 27, 2023 Category: Biomedical Engineering Authors: Hamidreza Hassanzadeh Khanmiri Fatemeh Yazdanfar Ahmad Mobed Fatemeh Rezamohammadi Mehrnoush Rahmani Tannaz Haghgouei Source Type: research
A standard 96-well based high throughput microfluidic perfusion biofilm reactor for in situ optical analysis
We describe the system fabrication and usage in optical analysis of biomass and viability of Escherichia coli (E. coli) biofilms. The HT-μPBR was set to perfuse at 1 mL/min corresponding to an average shear rate of approximately [Formula: see text] on the bottom surface of a single well. Biofilms were detected on well plate bottoms and measured using a fluorescence microscope and plate reader to determine biomass and viability. Samples cultured in the HT-μPBR showed increased biomass while maintaining viability after 24 h. The HT-μPBR can further be combined with HT antibiotic susceptibility testing and additional optic...
Source: Biomedical Microdevices - July 26, 2023 Category: Biomedical Engineering Authors: David McLeod Lai Wei Zhenyu Li Source Type: research
Ultrasensitive FET biosensor chip based on self-assembled organic nanoporous membrane for femtomolar detection of Amyloid- β
Biomed Microdevices. 2023 Jul 20;25(3):25. doi: 10.1007/s10544-023-00667-x.ABSTRACTEarly diagnosis of Alzheimer's disease (AD) is critical for preventing disease progression, however, the diagnosis of AD remains challenging for most patients due to limitations of current sensing technologies. A common pathological feature found in AD-affected brains is the accumulation of Amyloid-β (Aβ) polypeptides, which lead to neurofibrillary tangles and neuroinflammatory plaques. Here, we developed a portable ultrasensitive FET biosensor chip based on a self-assembled nanoporous membrane for ultrasensitive detection of Aβ protein i...
Source: Biomedical Microdevices - July 20, 2023 Category: Biomedical Engineering Authors: Xiaona Cao Xiaoping Hu Ziyi Qiu Ting Xu Zhenhua Yu Zhe Li Huawei Jin Bingzhe Xu Source Type: research
Ultrasensitive FET biosensor chip based on self-assembled organic nanoporous membrane for femtomolar detection of Amyloid- β
Biomed Microdevices. 2023 Jul 20;25(3):25. doi: 10.1007/s10544-023-00667-x.ABSTRACTEarly diagnosis of Alzheimer's disease (AD) is critical for preventing disease progression, however, the diagnosis of AD remains challenging for most patients due to limitations of current sensing technologies. A common pathological feature found in AD-affected brains is the accumulation of Amyloid-β (Aβ) polypeptides, which lead to neurofibrillary tangles and neuroinflammatory plaques. Here, we developed a portable ultrasensitive FET biosensor chip based on a self-assembled nanoporous membrane for ultrasensitive detection of Aβ protein i...
Source: Biomedical Microdevices - July 20, 2023 Category: Biomedical Engineering Authors: Xiaona Cao Xiaoping Hu Ziyi Qiu Ting Xu Zhenhua Yu Zhe Li Huawei Jin Bingzhe Xu Source Type: research
Ultrasensitive FET biosensor chip based on self-assembled organic nanoporous membrane for femtomolar detection of Amyloid- β
Biomed Microdevices. 2023 Jul 20;25(3):25. doi: 10.1007/s10544-023-00667-x.ABSTRACTEarly diagnosis of Alzheimer's disease (AD) is critical for preventing disease progression, however, the diagnosis of AD remains challenging for most patients due to limitations of current sensing technologies. A common pathological feature found in AD-affected brains is the accumulation of Amyloid-β (Aβ) polypeptides, which lead to neurofibrillary tangles and neuroinflammatory plaques. Here, we developed a portable ultrasensitive FET biosensor chip based on a self-assembled nanoporous membrane for ultrasensitive detection of Aβ protein i...
Source: Biomedical Microdevices - July 20, 2023 Category: Biomedical Engineering Authors: Xiaona Cao Xiaoping Hu Ziyi Qiu Ting Xu Zhenhua Yu Zhe Li Huawei Jin Bingzhe Xu Source Type: research
Ultrasensitive FET biosensor chip based on self-assembled organic nanoporous membrane for femtomolar detection of Amyloid- β
Biomed Microdevices. 2023 Jul 20;25(3):25. doi: 10.1007/s10544-023-00667-x.ABSTRACTEarly diagnosis of Alzheimer's disease (AD) is critical for preventing disease progression, however, the diagnosis of AD remains challenging for most patients due to limitations of current sensing technologies. A common pathological feature found in AD-affected brains is the accumulation of Amyloid-β (Aβ) polypeptides, which lead to neurofibrillary tangles and neuroinflammatory plaques. Here, we developed a portable ultrasensitive FET biosensor chip based on a self-assembled nanoporous membrane for ultrasensitive detection of Aβ protein i...
Source: Biomedical Microdevices - July 20, 2023 Category: Biomedical Engineering Authors: Xiaona Cao Xiaoping Hu Ziyi Qiu Ting Xu Zhenhua Yu Zhe Li Huawei Jin Bingzhe Xu Source Type: research
Ultrasensitive FET biosensor chip based on self-assembled organic nanoporous membrane for femtomolar detection of Amyloid- β
Biomed Microdevices. 2023 Jul 20;25(3):25. doi: 10.1007/s10544-023-00667-x.ABSTRACTEarly diagnosis of Alzheimer's disease (AD) is critical for preventing disease progression, however, the diagnosis of AD remains challenging for most patients due to limitations of current sensing technologies. A common pathological feature found in AD-affected brains is the accumulation of Amyloid-β (Aβ) polypeptides, which lead to neurofibrillary tangles and neuroinflammatory plaques. Here, we developed a portable ultrasensitive FET biosensor chip based on a self-assembled nanoporous membrane for ultrasensitive detection of Aβ protein i...
Source: Biomedical Microdevices - July 20, 2023 Category: Biomedical Engineering Authors: Xiaona Cao Xiaoping Hu Ziyi Qiu Ting Xu Zhenhua Yu Zhe Li Huawei Jin Bingzhe Xu Source Type: research
Ultrasensitive FET biosensor chip based on self-assembled organic nanoporous membrane for femtomolar detection of Amyloid- β
Biomed Microdevices. 2023 Jul 20;25(3):25. doi: 10.1007/s10544-023-00667-x.ABSTRACTEarly diagnosis of Alzheimer's disease (AD) is critical for preventing disease progression, however, the diagnosis of AD remains challenging for most patients due to limitations of current sensing technologies. A common pathological feature found in AD-affected brains is the accumulation of Amyloid-β (Aβ) polypeptides, which lead to neurofibrillary tangles and neuroinflammatory plaques. Here, we developed a portable ultrasensitive FET biosensor chip based on a self-assembled nanoporous membrane for ultrasensitive detection of Aβ protein i...
Source: Biomedical Microdevices - July 20, 2023 Category: Biomedical Engineering Authors: Xiaona Cao Xiaoping Hu Ziyi Qiu Ting Xu Zhenhua Yu Zhe Li Huawei Jin Bingzhe Xu Source Type: research
