A discussion about the velocity distribution commonly used as the boundary condition in surface acoustic wave numerical simulations
This study suggests not replacing the piezoelectric actuation with the boundary condition to avoid inaccuracy in resulting fields that are being used in calculations of particle tracing and acoustic radiation forces.PMID:37874402 | DOI:10.1007/s10544-023-00679-7 (Source: Biomedical Microdevices)
Source: Biomedical Microdevices - October 24, 2023 Category: Biomedical Engineering Authors: Farnaz Jazini Dorcheh Majid Ghassemi Source Type: research

A discussion about the velocity distribution commonly used as the boundary condition in surface acoustic wave numerical simulations
This study suggests not replacing the piezoelectric actuation with the boundary condition to avoid inaccuracy in resulting fields that are being used in calculations of particle tracing and acoustic radiation forces.PMID:37874402 | DOI:10.1007/s10544-023-00679-7 (Source: Biomedical Microdevices)
Source: Biomedical Microdevices - October 24, 2023 Category: Biomedical Engineering Authors: Farnaz Jazini Dorcheh Majid Ghassemi Source Type: research

Assessing the manufacturable 32-channel cochlear electrode array: evaluation results for clinical trials
Biomed Microdevices. 2023 Oct 23;25(4):41. doi: 10.1007/s10544-023-00681-z.ABSTRACTReliability evaluation results of a manufacturable 32-channel cochlear electrode array are reported in this paper. Applying automated laser micro-machining process and a layer-by-layer silicone deposition scheme, authors developed the manufacturing methods of the electrode array for fine patterning and mass production. The developed electrode array has been verified through the requirements specified by the ISO Standard 14708-7. And the insertion trauma of the electrode array has been evaluated based on human temporal bone studies. According...
Source: Biomedical Microdevices - October 23, 2023 Category: Biomedical Engineering Authors: Gwangjin Choi Yoonhee Ha Doo-Hee Kim Soowon Shin Junewoo Hyun Sangwoo Kim Seung-Ha Oh Kyou-Sik Min Source Type: research

Assessing the manufacturable 32-channel cochlear electrode array: evaluation results for clinical trials
Biomed Microdevices. 2023 Oct 23;25(4):41. doi: 10.1007/s10544-023-00681-z.ABSTRACTReliability evaluation results of a manufacturable 32-channel cochlear electrode array are reported in this paper. Applying automated laser micro-machining process and a layer-by-layer silicone deposition scheme, authors developed the manufacturing methods of the electrode array for fine patterning and mass production. The developed electrode array has been verified through the requirements specified by the ISO Standard 14708-7. And the insertion trauma of the electrode array has been evaluated based on human temporal bone studies. According...
Source: Biomedical Microdevices - October 23, 2023 Category: Biomedical Engineering Authors: Gwangjin Choi Yoonhee Ha Doo-Hee Kim Soowon Shin Junewoo Hyun Sangwoo Kim Seung-Ha Oh Kyou-Sik Min Source Type: research

Role of interleukin 6 and its soluble receptor on the diffusion barrier dysfunction of alveolar tissue
In this study, alveolar-like tissue was reconstructed in a microfluidic device with: (1) human microvascular lung endothelial cells (HULEC-5a) cultured under flow-induced shear stress and (2) human epithelial cells (Calu-3) cultured at air-liquid interface. The effects of IL-6 and the soluble form of its receptor (sIL-6R) on the permeability, electrical resistance, and morphology of the endothelial and epithelial layers were evaluated. The diffusion barrier properties of both the endothelial and epithelial layers were significantly degraded only when IL-6 treatment was combined with sIL-6R. As suggested by recent review an...
Source: Biomedical Microdevices - October 18, 2023 Category: Biomedical Engineering Authors: Chao Sui Woo Lee Source Type: research

Role of interleukin 6 and its soluble receptor on the diffusion barrier dysfunction of alveolar tissue
In this study, alveolar-like tissue was reconstructed in a microfluidic device with: (1) human microvascular lung endothelial cells (HULEC-5a) cultured under flow-induced shear stress and (2) human epithelial cells (Calu-3) cultured at air-liquid interface. The effects of IL-6 and the soluble form of its receptor (sIL-6R) on the permeability, electrical resistance, and morphology of the endothelial and epithelial layers were evaluated. The diffusion barrier properties of both the endothelial and epithelial layers were significantly degraded only when IL-6 treatment was combined with sIL-6R. As suggested by recent review an...
Source: Biomedical Microdevices - October 18, 2023 Category: Biomedical Engineering Authors: Chao Sui Woo Lee Source Type: research

Role of interleukin 6 and its soluble receptor on the diffusion barrier dysfunction of alveolar tissue
In this study, alveolar-like tissue was reconstructed in a microfluidic device with: (1) human microvascular lung endothelial cells (HULEC-5a) cultured under flow-induced shear stress and (2) human epithelial cells (Calu-3) cultured at air-liquid interface. The effects of IL-6 and the soluble form of its receptor (sIL-6R) on the permeability, electrical resistance, and morphology of the endothelial and epithelial layers were evaluated. The diffusion barrier properties of both the endothelial and epithelial layers were significantly degraded only when IL-6 treatment was combined with sIL-6R. As suggested by recent review an...
Source: Biomedical Microdevices - October 18, 2023 Category: Biomedical Engineering Authors: Chao Sui Woo Lee Source Type: research

Role of interleukin 6 and its soluble receptor on the diffusion barrier dysfunction of alveolar tissue
In this study, alveolar-like tissue was reconstructed in a microfluidic device with: (1) human microvascular lung endothelial cells (HULEC-5a) cultured under flow-induced shear stress and (2) human epithelial cells (Calu-3) cultured at air-liquid interface. The effects of IL-6 and the soluble form of its receptor (sIL-6R) on the permeability, electrical resistance, and morphology of the endothelial and epithelial layers were evaluated. The diffusion barrier properties of both the endothelial and epithelial layers were significantly degraded only when IL-6 treatment was combined with sIL-6R. As suggested by recent review an...
Source: Biomedical Microdevices - October 18, 2023 Category: Biomedical Engineering Authors: Chao Sui Woo Lee Source Type: research

Use of high frequency electrorotation to identify cytoplasmic changes in cells non-disruptively
Biomed Microdevices. 2023 Oct 6;25(4):39. doi: 10.1007/s10544-023-00677-9.ABSTRACTIn this paper we demonstrate how the use of frequencies ranging from 50 kHz to 5 GHz in the analysis of cells by electrorotation can open the path to the identification of differences not detectable by conventional set-ups. Earlier works usually reported electrorotation devices operating below 20 MHz, limiting the response obtained to properties associated with the cell membrane. Those devices are thus unable to resolve the physiological properties in the cytoplasm. We used microwave-based technology to extend the frequency operation to 5 GHz...
Source: Biomedical Microdevices - October 6, 2023 Category: Biomedical Engineering Authors: Camila D M Campos Kevin T Uning Pawel Barmuta Tomislav Markovic Rahul Yadav Giovanni Mangraviti Ilja Ocket Willem Van Roy Liesbet Lagae Chengxun Liu Source Type: research

Use of high frequency electrorotation to identify cytoplasmic changes in cells non-disruptively
Biomed Microdevices. 2023 Oct 6;25(4):39. doi: 10.1007/s10544-023-00677-9.ABSTRACTIn this paper we demonstrate how the use of frequencies ranging from 50 kHz to 5 GHz in the analysis of cells by electrorotation can open the path to the identification of differences not detectable by conventional set-ups. Earlier works usually reported electrorotation devices operating below 20 MHz, limiting the response obtained to properties associated with the cell membrane. Those devices are thus unable to resolve the physiological properties in the cytoplasm. We used microwave-based technology to extend the frequency operation to 5 GHz...
Source: Biomedical Microdevices - October 6, 2023 Category: Biomedical Engineering Authors: Camila D M Campos Kevin T Uning Pawel Barmuta Tomislav Markovic Rahul Yadav Giovanni Mangraviti Ilja Ocket Willem Van Roy Liesbet Lagae Chengxun Liu Source Type: research

Use of high frequency electrorotation to identify cytoplasmic changes in cells non-disruptively
Biomed Microdevices. 2023 Oct 6;25(4):39. doi: 10.1007/s10544-023-00677-9.ABSTRACTIn this paper we demonstrate how the use of frequencies ranging from 50 kHz to 5 GHz in the analysis of cells by electrorotation can open the path to the identification of differences not detectable by conventional set-ups. Earlier works usually reported electrorotation devices operating below 20 MHz, limiting the response obtained to properties associated with the cell membrane. Those devices are thus unable to resolve the physiological properties in the cytoplasm. We used microwave-based technology to extend the frequency operation to 5 GHz...
Source: Biomedical Microdevices - October 6, 2023 Category: Biomedical Engineering Authors: Camila D M Campos Kevin T Uning Pawel Barmuta Tomislav Markovic Rahul Yadav Giovanni Mangraviti Ilja Ocket Willem Van Roy Liesbet Lagae Chengxun Liu Source Type: research

Use of high frequency electrorotation to identify cytoplasmic changes in cells non-disruptively
Biomed Microdevices. 2023 Oct 6;25(4):39. doi: 10.1007/s10544-023-00677-9.ABSTRACTIn this paper we demonstrate how the use of frequencies ranging from 50 kHz to 5 GHz in the analysis of cells by electrorotation can open the path to the identification of differences not detectable by conventional set-ups. Earlier works usually reported electrorotation devices operating below 20 MHz, limiting the response obtained to properties associated with the cell membrane. Those devices are thus unable to resolve the physiological properties in the cytoplasm. We used microwave-based technology to extend the frequency operation to 5 GHz...
Source: Biomedical Microdevices - October 6, 2023 Category: Biomedical Engineering Authors: Camila D M Campos Kevin T Uning Pawel Barmuta Tomislav Markovic Rahul Yadav Giovanni Mangraviti Ilja Ocket Willem Van Roy Liesbet Lagae Chengxun Liu Source Type: research

Use of high frequency electrorotation to identify cytoplasmic changes in cells non-disruptively
Biomed Microdevices. 2023 Oct 6;25(4):39. doi: 10.1007/s10544-023-00677-9.ABSTRACTIn this paper we demonstrate how the use of frequencies ranging from 50 kHz to 5 GHz in the analysis of cells by electrorotation can open the path to the identification of differences not detectable by conventional set-ups. Earlier works usually reported electrorotation devices operating below 20 MHz, limiting the response obtained to properties associated with the cell membrane. Those devices are thus unable to resolve the physiological properties in the cytoplasm. We used microwave-based technology to extend the frequency operation to 5 GHz...
Source: Biomedical Microdevices - October 6, 2023 Category: Biomedical Engineering Authors: Camila D M Campos Kevin T Uning Pawel Barmuta Tomislav Markovic Rahul Yadav Giovanni Mangraviti Ilja Ocket Willem Van Roy Liesbet Lagae Chengxun Liu Source Type: research

Use of high frequency electrorotation to identify cytoplasmic changes in cells non-disruptively
Biomed Microdevices. 2023 Oct 6;25(4):39. doi: 10.1007/s10544-023-00677-9.ABSTRACTIn this paper we demonstrate how the use of frequencies ranging from 50 kHz to 5 GHz in the analysis of cells by electrorotation can open the path to the identification of differences not detectable by conventional set-ups. Earlier works usually reported electrorotation devices operating below 20 MHz, limiting the response obtained to properties associated with the cell membrane. Those devices are thus unable to resolve the physiological properties in the cytoplasm. We used microwave-based technology to extend the frequency operation to 5 GHz...
Source: Biomedical Microdevices - October 6, 2023 Category: Biomedical Engineering Authors: Camila D M Campos Kevin T Uning Pawel Barmuta Tomislav Markovic Rahul Yadav Giovanni Mangraviti Ilja Ocket Willem Van Roy Liesbet Lagae Chengxun Liu Source Type: research

Use of high frequency electrorotation to identify cytoplasmic changes in cells non-disruptively
Biomed Microdevices. 2023 Oct 6;25(4):39. doi: 10.1007/s10544-023-00677-9.ABSTRACTIn this paper we demonstrate how the use of frequencies ranging from 50 kHz to 5 GHz in the analysis of cells by electrorotation can open the path to the identification of differences not detectable by conventional set-ups. Earlier works usually reported electrorotation devices operating below 20 MHz, limiting the response obtained to properties associated with the cell membrane. Those devices are thus unable to resolve the physiological properties in the cytoplasm. We used microwave-based technology to extend the frequency operation to 5 GHz...
Source: Biomedical Microdevices - October 6, 2023 Category: Biomedical Engineering Authors: Camila D M Campos Kevin T Uning Pawel Barmuta Tomislav Markovic Rahul Yadav Giovanni Mangraviti Ilja Ocket Willem Van Roy Liesbet Lagae Chengxun Liu Source Type: research