External quality assessment scheme for sperm DNA fragmentation: a pilot study in China
ConclusionThis is the first study to evaluate the EQA program on SDF, which involved a number of laboratories and was demonstrated to be feasible. It is recommended that all laboratories participate in the EQA of SDF to ensure the accuracy of the results. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - November 28, 2023 Category: Urology & Nephrology Source Type: research
Association between sleep quality and nocturnal erection monitor by RigiScan in erectile dysfunction patients: a prospective study using fitbit charge 2
ConclusionsTherefore, our study strongly suggests a close association between sleep parameters and NPTR parameters. It emphasizes the importance of incorporating sleep monitoring alongside nocturnal erection monitoring to enhance the reliability of the NPTR results. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - November 27, 2023 Category: Urology & Nephrology Source Type: research
Dnali1 is required for sperm motility and male fertility in mice
ConclusionsOur results uncover a role of DNALI1 in sperm motility and male fertility in mice, and demonstrate that ICSI overcomesDnali1-associated male infertility, thus providing guidance for the diagnosis and genetic counseling ofDNALI1-associated human infertility. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - November 23, 2023 Category: Urology & Nephrology Source Type: research
Male contraception: narrative review of ongoing research
ConclusionsThere exist several hurdles to novel male contraception. Therapeutic development takes decades of time, meticulous work, and financial investment, but with so many strong candidates it is our hope that there will soon be several safe, effective, and reversible contraceptive options available to male patients. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - November 9, 2023 Category: Urology & Nephrology Source Type: research
The role of red ginseng in men ’s reproductive health: a literature review
ConclusionsThe application of RG for the treatment of male infertility, erectile dysfunction, and prostate diseases has the potential to contribute to MRH. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - October 26, 2023 Category: Urology & Nephrology Source Type: research
Suspension of the penis – dissection, anatomical description and highlighting of anatomical risks in sectioning the suspensory ligaments
ConclusionsThe dissections were conducted in layers, corresponding to the operative steps for the penile augmentation procedures. We believe that our study highlights the anatomical basis necessary to safely perform these surgeries. The study contributes to the description of the anatomical variability of the ligaments and logically presents details that contribute to preventing most surgical incidents. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - October 24, 2023 Category: Urology & Nephrology Source Type: research
Motivational stimuli to donate sperm among non-donor students
ConclusionsYoung single men represent a suitable cohort for anonymous donation. Financial reward and willingness to help others are important positive incentives while anonymity preservation is crucial to maintain their willingness towards SD. Regulatory shifting towards open-identity SD necessitates the establishment of an alternative “potential pool” population as a reliable source to recruit donors. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - October 17, 2023 Category: Urology & Nephrology Source Type: research
Mechanism of Shugan Yidan fang, a Chinese herbal formula, in rat model of premature ejaculation
ConclusionsOur study provided evidence for the beneficial effect of Shugan Yidan fang in PE therapy, and proposed a preliminary potential mechanism for the clinical application of the formula. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - October 3, 2023 Category: Urology & Nephrology Source Type: research
Mechanism of Shugan Yidan fan, a Chinese herbal formula, in rat model of premature ejaculation
ConclusionsOur study provided evidence for the beneficial effect of Shugan Yidan fang in PE therapy, and proposed a preliminary potential mechanism for the clinical application of the formula. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - October 3, 2023 Category: Urology & Nephrology Source Type: research
Epigenetics, cryptorchidism, and infertility
ConclusionOur findings suggest that epigenetic mechanisms are critical to better understanding the root causes underlying male infertility related to cryptorchidism and its possible transgenerational transmission. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - September 21, 2023 Category: Urology & Nephrology Source Type: research
Micronutrient supplements as antioxidants in improving sperm quality and reducing DNA fragmentation
ConclusionsMicronutrient supplementation can improve sperm quality and DNA integrity in infertile men. Men with infertility and significant sperm DNA fragmentation who take antioxidants for three months experience a reduction in DNA fragmentation index and an increase in sperm quality as measured by the semen analysis.Trial registrationNCT04509583. Registered 12 August 2020, Hue University of Medicine and Pharmacy Ethics Committee —Retrospectively registered. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - September 14, 2023 Category: Urology & Nephrology Source Type: research
Quality of testicular spermatozoa improves with changes in composition of culture medium
ConclusionThe results demonstrated that in vitro incubation of testicular spermatozoa improved their motility more effectively than Ham ’s F10 medium in the short term (2 h), but had no effect on epididymal spermatozoa. Since the physiology of testicular spermatozoa is different from that of ejaculated spermatozoa, it seems that a special environment should be designed and used for each of them. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - September 7, 2023 Category: Urology & Nephrology Source Type: research
Stepwise mini-incision microdissection testicular sperm extraction in NOA patients with a history of cryptorchidism: a case –control study
ConclusionsIn conclusion, our study suggests that the stepwise mini-incision mTESE could be a promising approach for sperm retrieval in NOA men with a history of cryptorchidism. While the technique may potentially reduce operation time and surgical invasiveness, further research is needed to validate these findings on a larger scale. The results also suggest that age at orchidopexy may affect SRR and have important implications for the management of cryptorchidism. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - August 17, 2023 Category: Urology & Nephrology Source Type: research
Testicular sperm aspiration has a poor effect in predicting micro-TESE outcomes in NOA patients with AZFc deletion
ConclusionThere is a high probability of successful sperm acquisition in the testis of men undergoing micro-TESE. In this group of patients, age, testicular volume, FSH levels, LH levels, and T levels may have little bearing on the micro-TESE outcome. In patients whose preoperative TESA revealed the absence of sperm, the probability of obtaining sperm by micro-TESE remained high (65.1%); negative TESA results appeared to not influence the SRR (63.8%) in patients undergoing micro-TESE. (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - August 10, 2023 Category: Urology & Nephrology Source Type: research
Cooperative cell –cell actin network remodeling to perform Gap junction endocytosis
ConclusionsTogether, these data suggest that the endocytosis of GJP is an example of a unique cooperative mechanism between the Donor (the traction of its actin cables) and the Acceptor cells (forming the actin ring). (Source: Basic and Clinical Andrology)
Source: Basic and Clinical Andrology - August 3, 2023 Category: Urology & Nephrology Source Type: research
