Analytical and Bioanalytical Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Artificial neural networks in the modeling of the catalytic activity of a biosensor composed of conjugated polymers and urease
Anal Bioanal Chem. 2024 Jan 5. doi: 10.1007/s00216-023-05114-7. Online ahead of print.ABSTRACTThin films of conjugated polymer and enzyme can be used to unravel the interaction between components in a biosensor. Using artificial neural networks (ANNs) improves data interpretability and helps construct models with great capacity for classifying and processing information. The present work used kinetic data from the catalytic activity of urease immobilized in different conjugated polymers to create ANN models using time, substrate concentration, and absorbance as input variables since the models had absorbance in a posterior...
Source: Analytical and Bioanalytical Chemistry - January 5, 2024 Category: Chemistry Authors: Cl éber Gomes de Jesus Rebeca da Rocha Rodrigues Carlos Alexandre Moreira da Silva Laura Oliveira P éres Source Type: research

Label-free detection of biomolecules using inductively coupled plasma mass spectrometry (ICP-MS)
Anal Bioanal Chem. 2024 Jan 4. doi: 10.1007/s00216-023-05106-7. Online ahead of print.ABSTRACTBioassays using inductively coupled plasma mass spectrometry (ICP-MS) have gained increasing attention because of the high sensitivity of ICP-MS and the various strategies of labeling biomolecules with detectable metal tags. The classic strategy to tag the target biomolecules is through direct antibody-antigen interaction and DNA hybridization, and requires the separation of the bound from the unbound tags. Label-free ICP-MS techniques for biomolecular assays do not require direct labeling: they generate detectable metal ions indi...
Source: Analytical and Bioanalytical Chemistry - January 4, 2024 Category: Chemistry Authors: Jianyu Hu Xiaowen Yan X Chris Le Source Type: research

Comparison of LC-MS-based methods for the determination of carboxylic acids in animal matrices
Anal Bioanal Chem. 2024 Jan 5. doi: 10.1007/s00216-023-05113-8. Online ahead of print.ABSTRACTCarboxylic acids (CAs) are key players in human and animal metabolism. As they are hardly retained under reversed-phase liquid chromatography (RP-LC) conditions in their native form, derivatization is an option to make them accessible to RP-LC and simultaneously increase their response for mass spectrometric detection. In this work, two RP-LC tandem mass spectrometry-based methods using aniline or 3-nitrophenylhydrazine (3-NPH) as derivatization agents were compared with respect to several factors including completeness of derivat...
Source: Analytical and Bioanalytical Chemistry - January 4, 2024 Category: Chemistry Authors: Heidi E Schwartz-Zimmermann Manuel H ündler Nicole Reiterer Sara Ricci Raul Rivera-Chacon Ezequias Castillo-Lopez Qendrim Zebeli Franz Berthiller Source Type: research

Development of a high-performance thin-layer chromatography-based method for targeted glycerolipidome profiling of microalgae
Anal Bioanal Chem. 2024 Jan 4. doi: 10.1007/s00216-023-05101-y. Online ahead of print.ABSTRACTThe conditionally essential very-long-chain polyunsaturated fatty acids (VLC-PUFAs), such as eicosapentaenoic acid (EPA, C20:5 n-3), play a vital role in human nutrition. Their biological activity is thereby greatly influenced by the distinct glycerolipid molecule that they are esterified to. Here, microalgae differ from the conventional source, fish oil, both in quantity and distribution of VLC-PUFAs among the glycerolipidome. Therefore, the aim of this study was to develop a fast and reliable one-dimensional high-performance thi...
Source: Analytical and Bioanalytical Chemistry - January 3, 2024 Category: Chemistry Authors: Kolos Makay Carola Griehl Claudia Grewe Source Type: research

Elemental analysis challenge
Anal Bioanal Chem. 2024 Jan;416(1):1-2. doi: 10.1007/s00216-023-05037-3. Epub 2024 Jan 2.NO ABSTRACTPMID:38163820 | DOI:10.1007/s00216-023-05037-3 (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - January 1, 2024 Category: Chemistry Authors: Juris Meija Source Type: research

Solution to best measurement challenge
Anal Bioanal Chem. 2024 Jan;416(1):3-4. doi: 10.1007/s00216-023-05044-4. Epub 2024 Jan 2.NO ABSTRACTPMID:38163821 | DOI:10.1007/s00216-023-05044-4 (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - January 1, 2024 Category: Chemistry Authors: Juris Meija Source Type: research

Comparison of high-resolution mass spectrometry acquisition methods for the simultaneous quantification and identification of per- and polyfluoroalkyl substances (PFAS)
This study validated HRMS acquisition approaches for quantification (based upon precursor data) and exploration of identification workflows for a range of PFAS compounds.PMID:38159142 | DOI:10.1007/s00216-023-05075-x (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - December 30, 2023 Category: Chemistry Authors: Jordan M Partington Sahil Rana Drew Szabo Tarun Anumol Bradley O Clarke Source Type: research

Fluorometric and colorimetric quantitative analysis platform for acid phosphatase by cerium ions-directed AIE and oxidase-like activity
Anal Bioanal Chem. 2023 Dec 27. doi: 10.1007/s00216-023-05103-w. Online ahead of print.ABSTRACTA facile and sensitive fluorescent and colorimetric dual-readout assay for detection of acid phosphatase (ACP) was developed via Ce(III) ions-directed aggregation-induced emission (AIE) of glutathione-protected gold nanoclusters (GSH-AuNCs) and oxidase-mimicking activity of Ce(IV) ions. Free Ce(IV) ions exhibited a strong oxidase-mimetic activity, catalytically oxidizing colorless 3,3',5,5'-tetramethylbenzidine (TMB) into its blue product oxTMB in the presence of dissolved O2, thus triggering a remarkable color reaction detected ...
Source: Analytical and Bioanalytical Chemistry - December 26, 2023 Category: Chemistry Authors: Qing Li Yue Gao Si-Hua Liu Source Type: research