Analytical and Bioanalytical Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Correction to: Forensic profiling of smokeless powders (SLPs) by gas chromatography-mass spectrometry (GC ‑MS): a systematic investigation into injector conditions and their effect on the characterisation of samples
Anal Bioanal Chem. 2024 Mar 7. doi: 10.1007/s00216-024-05218-8. Online ahead of print.NO ABSTRACTPMID:38448653 | DOI:10.1007/s00216-024-05218-8 (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - March 6, 2024 Category: Chemistry Authors: Blake Kesic Niamh McCann Samantha L Bowerbank Troy Standley Jana Liechti John R Dean Matteo D Gallidabino Source Type: research

Synergistically enhancing electrocatalysis and non-enzymatic sensing for glucose by iridium single-atom/nickel oxide/N-doped graphene
Anal Bioanal Chem. 2024 Mar 5. doi: 10.1007/s00216-024-05226-8. Online ahead of print.ABSTRACTThe development of novel catalyst with high catalytic activity is important for electrochemical non-enzymatic glucose sensing. Here, iridium single-atom/nickel oxide nanoparticle/N-doped graphene nanosheet (Ir1/NiO/NG) with the loading of 1.13 wt% Ir was successfully synthesized for constructing electrochemical non-enzymatic glucose sensor for the first time. The morphology and structure of Ir1/NiO/NG were characterized by XRD, SEM, TEM, HRTEM, and XPS, and the presence of Ir SAs was confirmed by AC-HAADF-STEM. The Ir1/NiO/NG show...
Source: Analytical and Bioanalytical Chemistry - March 5, 2024 Category: Chemistry Authors: Yaojiang Zhou Wen Wei Wenli Lei Fudong Li Jiaxi Shu Zixuan Deng Wenyu Hui Yuanmeng Zhao Changsheng Shan Source Type: research

Recent developments and challenges in resistance-based hydrogen gas sensors based on metal oxide semiconductors
This article provides a comprehensive review of the surface reaction mechanisms and recent research progress in optimizing the gas sensing performance of MOS-based resistive hydrogen gas sensors (MOS-R-HGS). Particularly, the advancements in metal-assisted or doped MOS, mixed metal oxide (MO)-MOS composites, MOS-carbon composites, and metal-organic framework-derived (MOF)-MOS composites are extensively summarized. Finally, the future research directions and possibilities in this field are discussed.PMID:38443743 | DOI:10.1007/s00216-024-05213-z (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - March 5, 2024 Category: Chemistry Authors: Lili Gao Ye Tian Altaf Hussain Yiran Guan Guobao Xu Source Type: research

Development of surface-enhanced Raman scattering-sensing Method by combining novel Ag@Au core/shell nanoparticle-based SERS probe with hybridization chain reaction for high-sensitive detection of hepatitis C virus nucleic acid
In this study, by combining Ag@Au core/shell nanoparticle (Ag@AuNP)-based surface-enhanced Raman scattering (SERS) tag with hybridization chain reaction (HCR), a novel SERS-sensing method was developed for the ultrasensitive detection of HCV nucleic acid. This SERS-sensing system comprised two different SERS tags, which were constructed by modifying Ag@AuNP with a Raman reporter molecule of 4-ethynylbezaldehyde, two different hairpin-structured HCR sequences (H1 or H2), and a detection plate prepared by immobilizing a capture DNA sequence onto the Ag@AuNP layer surface of the detection wells. When the target nucleic acid w...
Source: Analytical and Bioanalytical Chemistry - March 4, 2024 Category: Chemistry Authors: Ruiying Peng Wenchen Qi Ting Deng Yanmei Si Jishan Li Source Type: research

Potential of ion mobility mass spectrometry in cellulose ether analysis: substitution pattern of hydroxyethyl celluloses
Anal Bioanal Chem. 2024 Mar 4. doi: 10.1007/s00216-024-05224-w. Online ahead of print.ABSTRACTIon mobility mass spectrometry (ESI-tims-ToF-MS, syringe pump infusion) has been applied to glucose and oligosaccharide ethers derived from hydroxyethyl-methyl celluloses (HEMC) and hydroxyethyl celluloses (HEC) after permethylation and partial depolymerization: by hydrolysis without or with subsequent reductive amination with m-amino benzoic acid (mABA) or by reductive cleavage. As model compounds without tandem substitution methoxyethylated methylcellulose was used. Regioisomeric glucose ethers were separated according to their ...
Source: Analytical and Bioanalytical Chemistry - March 4, 2024 Category: Chemistry Authors: Petra Mischnick Sarah Schleicher Source Type: research

Application of gold nanoclusters in fluorescence sensing and biological detection
Anal Bioanal Chem. 2024 Mar 4. doi: 10.1007/s00216-024-05220-0. Online ahead of print.ABSTRACTGold nanoclusters (Au NCs) exhibit broad fluorescent spectra from visible to near-infrared regions and good enzyme-mimicking catalytic activities. Combined with excellent stability and exceptional biocompatibility, the Au NCs have been widely exploited in biomedicine such as biocatalysis and bioimaging. Especially, the long fluorescence lifetime and large Stokes shift attribute Au NCs to good probes for fluorescence sensing and biological detection. In this review, we systematically summarized the molecular structure and fluoresce...
Source: Analytical and Bioanalytical Chemistry - March 4, 2024 Category: Chemistry Authors: Kexin Tan Huizhen Ma Xiaoyu Mu Zhidong Wang Qi Wang Hao Wang Xiao-Dong Zhang Source Type: research

Determination of linearized pDNA template in mRNA production process using HPLC
Anal Bioanal Chem. 2024 Mar 5. doi: 10.1007/s00216-024-05204-0. Online ahead of print.ABSTRACTThe recent clinical success of messenger RNA (mRNA) technology in managing the Covid pandemic has triggered an unprecedented innovation in production and analytical technologies for this therapeutic modality. mRNA is produced by enzymatic transcription of plasmid DNA (pDNA) using polymerase in a cell-free process of in vitro transcription. After transcription, the pDNA is considered a process-related impurity and is removed from the mRNA product enzymatically, chromatographically, or by precipitation. Regulatory requirements are c...
Source: Analytical and Bioanalytical Chemistry - March 4, 2024 Category: Chemistry Authors: Marta Leban Tina Vodopivec Seravalli Martina Hauer Ernst B öhm Nina Mencin Sandra Potu šek Andrej Thompson Jurij Trontelj Ale š Štrancar Rok Sekirnik Source Type: research

Quantification of SARS-CoV-2 monoclonal IgG mass fraction by isotope dilution mass spectrometry
Anal Bioanal Chem. 2024 Mar 1. doi: 10.1007/s00216-024-05205-z. Online ahead of print.ABSTRACTThe availability of serology assays to measure antibodies against the SARS coronavirus 2 (SARS-CoV-2) expanded rapidly during the Covid-19 pandemic. The interchangeable use of such assays to monitor disease progression and immune protection requires their standardization, for which suitably characterized monoclonal antibody materials can be useful. The methods, based on isotope dilution mass spectrometry, to value assign the mass fraction of such a material in solution within the context of an international interlaboratory compari...
Source: Analytical and Bioanalytical Chemistry - March 1, 2024 Category: Chemistry Authors: G Martos M Bedu R D Josephs S Westwood R I Wielgosz Source Type: research

Self-assembly of CuAuTA nanozymes for intelligent detection of ginkgolic acids
Anal Bioanal Chem. 2024 Feb 28. doi: 10.1007/s00216-024-05221-z. Online ahead of print.ABSTRACTToxic ginkgolic acids (GAs) are a challenge for Ginkgo biloba-related food. Although a detection method for GAs is available, bulky instruments limit the field testing of GAs. Herein, by assembling gold nanoclusters with copper tannic acid (CuTA), CuAuTA nanocomposites were designed as peroxidase mimics for the colorimetric determination of GAs. Compared with single CuTA, the obtained CuAuTA nanocomposites possessed enhanced peroxidase-like properties. Based on the inhibitory effect of GAs for the catalytic activity of CuAuTA nan...
Source: Analytical and Bioanalytical Chemistry - February 28, 2024 Category: Chemistry Authors: Huimin Zhong Cong Jiang Jiahui Zou Guancheng Zhu Mengyue Cheng Yanyan Huang Source Type: research