The tightest self-assembled ruthenium metal-organic framework combined with proximity hybridization for ultrasensitive electrochemiluminescence analysis of paraquat
Anal Bioanal Chem. 2024 Mar 23. doi: 10.1007/s00216-024-05237-5. Online ahead of print.ABSTRACTMetal-organic frameworks (MOFs), as porous materials, have great potential for exploring high-performance electrochemiluminescence (ECL) probes. However, the constrained applicability of MOFs in the realm of ECL biosensing is primarily attributed to their inadequate water stability, which consequently impairs the overall ECL efficiency. Herein, we developed a competitive ECL biosensor based on a novel tightest structural ruthenium-based organic framework emitter combining the proximity hybridization-induced catalytic hairpin asse...
Source: Analytical and Bioanalytical Chemistry - March 23, 2024 Category: Chemistry Authors: Ling Qin Wenbin Liang Weiguo Yang Shenghan Tang Ruo Yuan Jun Yang Yan Li Shanshan Hu Source Type: research

Inorganic arsenic in seaweed: a fast HPLC-ICP-MS method without coelution of arsenosugars
Anal Bioanal Chem. 2024 Mar 23. doi: 10.1007/s00216-024-05250-8. Online ahead of print.ABSTRACTSeaweed is becoming increasingly popular in the Western diet as consumers opt for more sustainable food sources. However, seaweed is known to accumulate high levels of arsenic-which may be in the form of carcinogenic inorganic arsenic (iAs). Here we propose a fast method for the routine measurement of iAs in seaweed using HPLC-ICP-MS without coelution of arsenosugars that may complicate quantification. The developed method was optimised using design of experiments (DOE) and tested on a range of reference materials including TORT-...
Source: Analytical and Bioanalytical Chemistry - March 23, 2024 Category: Chemistry Authors: Rebecca Sim Marta Weyer Ásta H Pétursdóttir Source Type: research

The tightest self-assembled ruthenium metal-organic framework combined with proximity hybridization for ultrasensitive electrochemiluminescence analysis of paraquat
Anal Bioanal Chem. 2024 Mar 23. doi: 10.1007/s00216-024-05237-5. Online ahead of print.ABSTRACTMetal-organic frameworks (MOFs), as porous materials, have great potential for exploring high-performance electrochemiluminescence (ECL) probes. However, the constrained applicability of MOFs in the realm of ECL biosensing is primarily attributed to their inadequate water stability, which consequently impairs the overall ECL efficiency. Herein, we developed a competitive ECL biosensor based on a novel tightest structural ruthenium-based organic framework emitter combining the proximity hybridization-induced catalytic hairpin asse...
Source: Analytical and Bioanalytical Chemistry - March 23, 2024 Category: Chemistry Authors: Ling Qin Wenbin Liang Weiguo Yang Shenghan Tang Ruo Yuan Jun Yang Yan Li Shanshan Hu Source Type: research

Inorganic arsenic in seaweed: a fast HPLC-ICP-MS method without coelution of arsenosugars
Anal Bioanal Chem. 2024 Mar 23. doi: 10.1007/s00216-024-05250-8. Online ahead of print.ABSTRACTSeaweed is becoming increasingly popular in the Western diet as consumers opt for more sustainable food sources. However, seaweed is known to accumulate high levels of arsenic-which may be in the form of carcinogenic inorganic arsenic (iAs). Here we propose a fast method for the routine measurement of iAs in seaweed using HPLC-ICP-MS without coelution of arsenosugars that may complicate quantification. The developed method was optimised using design of experiments (DOE) and tested on a range of reference materials including TORT-...
Source: Analytical and Bioanalytical Chemistry - March 23, 2024 Category: Chemistry Authors: Rebecca Sim Marta Weyer Ásta H Pétursdóttir Source Type: research

Simultaneous determination of diquat, paraquat, glufosinate, and glyphosate in plasma by liquid chromatography/tandem mass spectrometry: from method development to clinical application
Anal Bioanal Chem. 2024 Mar 22. doi: 10.1007/s00216-024-05257-1. Online ahead of print.ABSTRACTDiquat (DQ), paraquat (PQ), glufosinate (GLU), and glyphosate (GLYP) are commonly used herbicides that have been confirmed to be toxic to humans. Rapid and accurate measurements of these toxicants in clinical practice are beneficial for the correct diagnosis and timely treatment of herbicide-poisoned patients. The present study aimed to establish an efficient, convenient, and reliable method to achieve the simultaneous quantification of DQ, PQ, GLU, and GLYP in human plasma using liquid chromatography-tandem mass spectrometry (LC...
Source: Analytical and Bioanalytical Chemistry - March 22, 2024 Category: Chemistry Authors: Maozhu Liu Fei Fan Jing Zhang Shiyong Fang Yangjuan Bai Yamei Li Yuangao Zou Yunfei An Xinhua Dai Source Type: research

Advanced tools for molecular characterization of bio-based and biodegradable polymers
Anal Bioanal Chem. 2024 Mar 22. doi: 10.1007/s00216-024-05255-3. Online ahead of print.ABSTRACTBio-based and biodegradable materials play a vital role in a sustainable and green economy. These materials must exhibit properties that are similar to or better than the properties of oil- or coal-based materials and require sophisticated synthesis technologies and detailed knowledge of structure-property correlations. For comprehensive molecular structure elucidation, advanced analytical methods, including coupled and hyphenated techniques that combine advanced fractionation and information-rich spectroscopic detectors, are an ...
Source: Analytical and Bioanalytical Chemistry - March 22, 2024 Category: Chemistry Authors: Ndumiso Sibanda Helen Pfukwa Paul Eselem Bungu Harald Pasch Source Type: research

Simultaneous determination of diquat, paraquat, glufosinate, and glyphosate in plasma by liquid chromatography/tandem mass spectrometry: from method development to clinical application
Anal Bioanal Chem. 2024 Mar 22. doi: 10.1007/s00216-024-05257-1. Online ahead of print.ABSTRACTDiquat (DQ), paraquat (PQ), glufosinate (GLU), and glyphosate (GLYP) are commonly used herbicides that have been confirmed to be toxic to humans. Rapid and accurate measurements of these toxicants in clinical practice are beneficial for the correct diagnosis and timely treatment of herbicide-poisoned patients. The present study aimed to establish an efficient, convenient, and reliable method to achieve the simultaneous quantification of DQ, PQ, GLU, and GLYP in human plasma using liquid chromatography-tandem mass spectrometry (LC...
Source: Analytical and Bioanalytical Chemistry - March 22, 2024 Category: Chemistry Authors: Maozhu Liu Fei Fan Jing Zhang Shiyong Fang Yangjuan Bai Yamei Li Yuangao Zou Yunfei An Xinhua Dai Source Type: research

Advanced tools for molecular characterization of bio-based and biodegradable polymers
Anal Bioanal Chem. 2024 Mar 22. doi: 10.1007/s00216-024-05255-3. Online ahead of print.ABSTRACTBio-based and biodegradable materials play a vital role in a sustainable and green economy. These materials must exhibit properties that are similar to or better than the properties of oil- or coal-based materials and require sophisticated synthesis technologies and detailed knowledge of structure-property correlations. For comprehensive molecular structure elucidation, advanced analytical methods, including coupled and hyphenated techniques that combine advanced fractionation and information-rich spectroscopic detectors, are an ...
Source: Analytical and Bioanalytical Chemistry - March 22, 2024 Category: Chemistry Authors: Ndumiso Sibanda Helen Pfukwa Paul Eselem Bungu Harald Pasch Source Type: research

Correction to: A new methodology to reveal potential nucleic acid modifications associated with the risk of endometrial cancer through dispersive solid ‑phase extraction coupled with UHPLC‑QE‑Orbitrap‑MS/MS and HPLC-UV
Anal Bioanal Chem. 2024 Mar 21. doi: 10.1007/s00216-024-05247-3. Online ahead of print.NO ABSTRACTPMID:38509355 | DOI:10.1007/s00216-024-05247-3 (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - March 21, 2024 Category: Chemistry Authors: Huanhuan Zhao Xiaoguang Zhang Lujie Zuo Li Li Hongfang Yang Mengyu Zhang Na Wang Qingzhong Jia Yan Liu Source Type: research

Ratiometric electrochemiluminescence sensing and intracellular imaging of ClO < sup > - < /sup > via resonance energy transfer
Anal Bioanal Chem. 2024 Mar 21. doi: 10.1007/s00216-024-05236-6. Online ahead of print.ABSTRACTElectrochemiluminescence resonance energy transfer (ECL-RET) is a versatile signal transduction strategy widely used in the fabrication of chem/biosensors. However, this technique has not yet been applied in visualized imaging analysis of intracellular species due to the insulating nature of the cell membrane. Here, we construct a ratiometric ECL-RET analytical method for hypochlorite ions (ClO-) by ECL luminophore, with a luminol derivative (L-012) as the donor and a fluorescence probe (fluorescein hydrazide) as the acceptor. L-...
Source: Analytical and Bioanalytical Chemistry - March 21, 2024 Category: Chemistry Authors: Cheng Ma Yujing Zhu Zhichen Zhang Xuan Chen Zhengping Ji Lu-Nan Zhang Qin Xu Source Type: research

Correction to: A new methodology to reveal potential nucleic acid modifications associated with the risk of endometrial cancer through dispersive solid ‑phase extraction coupled with UHPLC‑QE‑Orbitrap‑MS/MS and HPLC-UV
Anal Bioanal Chem. 2024 Mar 21. doi: 10.1007/s00216-024-05247-3. Online ahead of print.NO ABSTRACTPMID:38509355 | DOI:10.1007/s00216-024-05247-3 (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - March 21, 2024 Category: Chemistry Authors: Huanhuan Zhao Xiaoguang Zhang Lujie Zuo Li Li Hongfang Yang Mengyu Zhang Na Wang Qingzhong Jia Yan Liu Source Type: research

Advances in D-dimer testing: progress in harmonization of clinical assays and innovative detection methods
Anal Bioanal Chem. 2024 Mar 20. doi: 10.1007/s00216-024-05207-x. Online ahead of print.ABSTRACTThe D-dimer is a sensitive indicator of coagulation and fibrinolysis activation, especially valuable as a biomarker of intravascular thrombosis. Measurement of plasma D-dimer levels plays a crucial role in the diagnosis and monitoring of conditions such as deep vein thrombosis, pulmonary embolism, and disseminated intravascular coagulation. A variety of immunoassays, including enzyme-linked immunosorbent assays, latex-enhanced immunoturbidimetric assays, whole-blood aggregation analysis, and immunochromatography assays, are widel...
Source: Analytical and Bioanalytical Chemistry - March 20, 2024 Category: Chemistry Authors: Rong Zhao Mengran Li Peng Xiao Dewei Song Hongmei Li Source Type: research

A passing spaceship NMR challenge
Anal Bioanal Chem. 2024 Apr;416(9):1997-1998. doi: 10.1007/s00216-024-05210-2. Epub 2024 Mar 20.NO ABSTRACTPMID:38504060 | DOI:10.1007/s00216-024-05210-2 (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - March 20, 2024 Category: Chemistry Authors: Reinhard Meusinger Source Type: research

Solution to bridged bicyclic molecule NMR challenge
Anal Bioanal Chem. 2024 Apr;416(9):1999-2000. doi: 10.1007/s00216-024-05211-1. Epub 2024 Mar 20.NO ABSTRACTPMID:38504061 | DOI:10.1007/s00216-024-05211-1 (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - March 20, 2024 Category: Chemistry Authors: Andrii V Kozytskyi Andrii V Bondarenko Source Type: research

Reliable biological and multi-omics research through biometrology
Anal Bioanal Chem. 2024 Mar 20. doi: 10.1007/s00216-024-05239-3. Online ahead of print.ABSTRACTMetrology is the science of measurement and its applications, whereas biometrology is the science of biological measurement and its applications. Biometrology aims to achieve accuracy and consistency of biological measurements by focusing on the development of metrological traceability, biological reference measurement procedures, and reference materials. Irreproducibility of biological and multi-omics research results from different laboratories, platforms, and analysis methods is hampering the translation of research into clini...
Source: Analytical and Bioanalytical Chemistry - March 20, 2024 Category: Chemistry Authors: Lianhua Dong Yu Zhang Boqiang Fu Claudia Swart Huayan Jiang Yahui Liu Jim Huggett Robert Wielgosz Chunyan Niu Qianyi Li Yongzhuo Zhang Sang-Ryoul Park Zhiwei Sui Lianchao Yu Yangyang Liu Qing Xie Hongfu Zhang Yueyuxiao Yang Xinhua Dai Leming Shi Ye Yin Xi Source Type: research