Analytical and Bioanalytical Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

MNAzyme catalyzed signal amplification-mediated lateral flow biosensor for portable and sensitive detection of mycotoxin in food samples
Anal Bioanal Chem. 2023 Dec 20. doi: 10.1007/s00216-023-05096-6. Online ahead of print.ABSTRACTHere, an enzyme-free lateral flow aptasensor was designed by target-induced strand-displacement effect and followed by the activation of multi-component nucleic acid enzyme (MNAzyme)-mediated cleavage to enable rapid and portable ochratoxin A (OTA) detection. The substrate was prepared as an oligonucleotide strand modified with magnetic beads (MB) and human chorionic gonadotropin (hCG). The interaction of OTA with the aptamer induces the release of blocking DNA, which hybridized with three separated subunits of DNA, forming a seq...
Source: Analytical and Bioanalytical Chemistry - December 20, 2023 Category: Chemistry Authors: Yan Yang Yiheng Shi Xianlong Zhang Guoliang Li Source Type: research

Plant-based meat substitute analysis using microextraction with deep eutectic solvent followed by LC-MS/MS to determine acrylamide, 5-hydroxymethylfurfural and furaneol
Anal Bioanal Chem. 2023 Dec 21. doi: 10.1007/s00216-023-05107-6. Online ahead of print.ABSTRACTFor the analysis of plant-based meat substitutes and the determination of Maillard reaction products such as acrylamide, 5-hydroxymethylfurfural and furaneol, a novel and effective procedure based on hydrophobic natural deep eutectic solvent and liquid chromatography coupled with tandem mass spectrometry was developed for the first time. The 49 compositions of the deep eutectic solvents were designed and screened to select the most suitable option. The terpenoids eugenol and thymol in a molar ratio of 2:1 were selected as precurs...
Source: Analytical and Bioanalytical Chemistry - December 20, 2023 Category: Chemistry Authors: Dominika Osiecka Christina Vakh Patrycja Mako ś-Chełstowska Pawe ł Kubica Source Type: research

Applying a risk assessment guided evaluation for verifying comprehensive two-dimensional gas chromatography to analyse complex pharmaceuticals
In this study, we employ a risk assessment approach to identify critical parameters which might influence the qualitative results derived by online derivatisation - comprehensive two-dimensional gas chromatography coupled to a high-resolution time-of-flight mass spectrometer (GC × GC-HR-ToF-MS) for the analysis of the active pharmaceutical ingredient (API) sodium bituminosulfonate (SBS). To show the complexity and feasibility of such an approach, we focus on investigating three potential risk factors: sample preparation, vapourability, and the thermal stability of sulfonates. Through the individual evaluation of these pot...
Source: Analytical and Bioanalytical Chemistry - December 20, 2023 Category: Chemistry Authors: Lukas Schwalb Ole Tiemann Uwe K äfer Christopher Paul R üger Thomas Gr öger Ralf Zimmermann Source Type: research

High-temperature ultrafast ChipHPLC-MS
Anal Bioanal Chem. 2023 Dec 19. doi: 10.1007/s00216-023-05092-w. Online ahead of print.ABSTRACTHerein, we present a miniaturized chip-based HPLC approach coupled to electrospray ionization mass spectrometry utilizing temperature to achieve high-speed separations. The approach benefits from the low thermal mass of the microfluidic chip and can form an electrospray from the pre-heated mobile phase. With the help of this technology, isothermal and temperature-programmable operations up to 130°C were pursued to perform reversed-phase separations of pesticides in methanol and ethanol-containing eluents in less than 20 s.PMID:3...
Source: Analytical and Bioanalytical Chemistry - December 19, 2023 Category: Chemistry Authors: Chris Weise Hannes Westphal Rico Warias Detlev Belder Source Type: research

Correction to: Enzyme ‑targeted near‑infrared fluorescent probe for organophosphorus pesticide residue detection
Anal Bioanal Chem. 2023 Dec 19. doi: 10.1007/s00216-023-05112-9. Online ahead of print.NO ABSTRACTPMID:38112790 | DOI:10.1007/s00216-023-05112-9 (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - December 19, 2023 Category: Chemistry Authors: Shan Luo Ruichen Peng Ying Wang Xianjun Liu Jiali Ren Wang Li Ying Xiong Sili Yi Qian Wen Source Type: research

Investigation of metabolite alterations in the kidneys of methionine-choline-deficient mouse by mass spectrometry imaging
This study presents unique regional metabolic data, providing a more comprehensive understanding of the molecular characteristics of the MCD diet in the kidney.PMID:38108841 | DOI:10.1007/s00216-023-05091-x (Source: Analytical and Bioanalytical Chemistry)
Source: Analytical and Bioanalytical Chemistry - December 18, 2023 Category: Chemistry Authors: Xiaoqun Wang Yingying Hu Wentao Zhu Dianlei Wang Source Type: research

Single-atom Fe nanozymes with excellent oxidase-like and laccase-like activity for colorimetric detection of ascorbic acid and hydroquinone
Anal Bioanal Chem. 2023 Dec 18. doi: 10.1007/s00216-023-05077-9. Online ahead of print.ABSTRACTAlthough traditional Fe-based nanozymes have shown great potential, generally only a small proportion of the Fe atoms on the catalyst's surface are used. Herein, we synthesized single-atom Fe on N-doped graphene nanosheets (Fe-CNG) with high atom utilization efficiency and a unique coordination structure. Active oxygen species including superoxide radicals (O2•-) and singlet oxygen (1O2) were efficiently generated from the interaction of the Fe-CNG with dissolved oxygen in acidic conditions. The Fe-CNG nanozymes were found to d...
Source: Analytical and Bioanalytical Chemistry - December 18, 2023 Category: Chemistry Authors: Shushu Chu Mingyuan Xia Peng Xu Dalei Lin Yuanyuan Jiang Yizhong Lu Source Type: research

New analytical method for the determination of endocrine disruptors in human faeces using gas chromatography coupled to tandem mass spectrometry
Anal Bioanal Chem. 2023 Dec 18. doi: 10.1007/s00216-023-05087-7. Online ahead of print.ABSTRACTEndocrine-disrupting chemicals are environmental pollutants that can enter our bodies and cause diverse pathologies. Some bisphenols and parabens have been shown to be capable of modifying proper functioning of the endocrine system. Among other dysfunctions, endocrine-disrupting chemicals can cause changes in intestinal microbiota. Faeces are a convenient matrix that can be useful for identifying the quantity of endocrine disruptors that reach the intestine and the extent to which the organism is exposed to these pollutants. The ...
Source: Analytical and Bioanalytical Chemistry - December 18, 2023 Category: Chemistry Authors: Inmaculada Moscoso-Ruiz Samuel Cantarero-Malag ón Ana Rivas Alberto Zafra-G ómez Source Type: research

A liquid chromatography-mass spectrometry method for the enantioselective multiresidue determination of nine chiral agrochemicals in urine using an enrichment procedure based on graphitized carbon black
Anal Bioanal Chem. 2023 Dec 18. doi: 10.1007/s00216-023-05098-4. Online ahead of print.ABSTRACTMany agrochemicals are chiral molecules, and most of them are marketed as racemates or diastereomeric mixtures. Stereoisomers that are not the active enantiomer have little or no pesticidal activity and can exert serious toxic effects towards non-target organisms. Thus, investigating the possible exposure to different isomers of chiral pesticides is an urgent need. The present work was aimed at developing a new enantioselective high-performance liquid chromatography-mass spectrometry method for the simultaneous determination of n...
Source: Analytical and Bioanalytical Chemistry - December 18, 2023 Category: Chemistry Authors: Elena Lucci Lorenzo Antonelli Monica Gherardi Chiara Fanali Salvatore Fanali Anita Scipioni Paolo Lupattelli Alessandra Gentili Bezhan Chankvetadze Source Type: research

eCerto-versatile software for interlaboratory data evaluation and documentation during reference material production
Anal Bioanal Chem. 2023 Dec 18. doi: 10.1007/s00216-023-05099-3. Online ahead of print.ABSTRACTThe statistical tool eCerto was developed for the evaluation of measurement data to assign property values and associated uncertainties of reference materials. The analysis is based on collaborative studies of expert laboratories and was implemented using the R software environment. Emphasis was put on comparability of eCerto with SoftCRM, a statistical tool based on the certification strategy of the former Community Bureau of Reference. Additionally, special attention was directed towards easy usability from data collection thro...
Source: Analytical and Bioanalytical Chemistry - December 18, 2023 Category: Chemistry Authors: Jan Lisec Sebastian Recknagel Carsten Prinz Kristin Vogel Matthias Koch Roland Becker Source Type: research