Correction to: Evaluation of subclinical left ventricular myocardial systolic dysfunction in type 2 diabetes mellitus patients with and without diabetes peripheral neuropathy by global myocardial work
(Source: Acta Diabetologica)
Source: Acta Diabetologica - November 30, 2023 Category: Endocrinology Source Type: research

Association between continuous glucose monitoring-derived glycemic control indices and urinary biomarkers of diabetic kidney disease: Hyogo Diabetes Hypoglycemia Cognition Complications study
ConclusionThe findings of this study indicated that uNAG/Cr was elevated before albuminuria development and was associated with CGM-derived TIR and GRI. (Source: Acta Diabetologica)
Source: Acta Diabetologica - November 25, 2023 Category: Endocrinology Source Type: research

Relationship between family function, self-perceived burden and loneliness in patients with type 2 diabetes mellitus: a cross-lagged analysis
ConclusionsThe results of the cross-lagged analysis show that there is a mutually predictive and moderating relationship between family functioning and loneliness in patients with type 2 diabetes. Loneliness can predict the level of self-perceived burden at the next time point. (Source: Acta Diabetologica)
Source: Acta Diabetologica - November 22, 2023 Category: Endocrinology Source Type: research

Retinal age gap as a predictive biomarker for future risk of clinically significant diabetic retinopathy
ConclusionsWe found that higher retinal age gap was associated with an increased risk of incident DR. As an easy and non-invasive biomarker, the retinal age gap may serve as an informative tool to facilitate the individualized risk assessment and personalized screening protocol for DR. (Source: Acta Diabetologica)
Source: Acta Diabetologica - November 21, 2023 Category: Endocrinology Source Type: research

Body composition assessment in a large cohort of Olympic athletes with different training loads: possible reference values for fat mass and fat-free mass domains
ConclusionsOur findings might provide a basis to optimize the practical approach to body composition in athletes, highlighting the importance of considering indicators of fat mass and lean mass “simultaneously” and not specularly, according to different sport disciplines as well. Moreover, these data might contribute to standardize reference values for body composition in elite athletes, with a view to potentially helping to monitor and guide training regimens, prevent related detrimen tal practices and plan cardiometabolic prevention and rehabilitation programs. (Source: Acta Diabetologica)
Source: Acta Diabetologica - November 9, 2023 Category: Endocrinology Source Type: research

The effect of gestational diabetes mellitus on carotid artery intima-media thickness in and after pregnancy: a systematic review and meta-analysis
ConclusionsGDM in and after pregnancy is independently associated with subclinical atherosclerosis. The association between GDM and carotid remodeling is potentially mediated by the longstanding underlying risk. (Source: Acta Diabetologica)
Source: Acta Diabetologica - November 8, 2023 Category: Endocrinology Source Type: research

Statins and new-onset diabetes in primary prevention setting: an updated meta-analysis stratified by baseline diabetes risk
ConclusionGlobally, the use of statins in patients in primary prevention was associated with an increased risk of new-onset diabetes. In the stratified analysis, this association was observed only in the group of studies with a high baseline rate of events. (Source: Acta Diabetologica)
Source: Acta Diabetologica - November 7, 2023 Category: Endocrinology Source Type: research

Scans per day as predictors of optimal glycemic control in people with type 1 diabetes mellitus using flash glucose monitoring: what number of scans per day should raise a red flag?
ConclusionsThe results suggest that a higher frequency of daily scans by T1D patients using FGM systems leads to improved chronic glycemic control. The minimum recommended frequency for optimal control is 13 scans per day, and more than 6 daily scans are needed to improve HbA1c. (Source: Acta Diabetologica)
Source: Acta Diabetologica - November 6, 2023 Category: Endocrinology Source Type: research

The stress hyperglycemic ratio can predict the no-reflow phenomenon following saphenous vein graft intervention in patients with acute coronary syndrome
ConclusionsThis study showed that SHR, a parameter that can be easily calculated noninvasively, is an independent predictor of NRP development in ACS patients undergoing saphenous interventions. In addition, high thrombus burden and predilatation before stenting were also found to be factors that increase the likelihood of developing NRP. (Source: Acta Diabetologica)
Source: Acta Diabetologica - November 2, 2023 Category: Endocrinology Source Type: research

A comparative study using insulin pump therapy and continuous glucose monitoring in newly diagnosed very young children with type 1 diabetes: it is possible to bend the curve of HbA1c
ConclusionsEarly initiation of diabetes technologies is safe and able to determine a better long term glycemic control in young children with T1D. It also allows to flatten the trajectory of HbA1c, probably reducing microvascular, macrovascular and neurological complications of diabetes in this very peculiar age group. (Source: Acta Diabetologica)
Source: Acta Diabetologica - October 20, 2023 Category: Endocrinology Source Type: research

Assessment of selected muscle damage markers and zonulin concentration after maximum-intensity exercise in men with type 1 diabetes treated with a personal insulin pump
ConclusionMaximum-intensity exercise increased muscle and intestinal damage in T1D participants. In patients with lower physical activity, very-high-intensity exercise should be recommended with caution. Observing the anabolic-catabolic index may help individualize effort intensity in T1D individuals. (Source: Acta Diabetologica)
Source: Acta Diabetologica - October 20, 2023 Category: Endocrinology Source Type: research

Gremlin-1 in pregnancy and postpartum: relation to the fatty liver index, markers of bone health, glucose metabolism and gestational diabetes mellitus status
ConclusionGremlin-1 levels decreased significantly during pregnancy. The biomarker is not related to GDM status, but correlates negatively with the Insulinogenic Index, an index related to beta cell function.Trial Registry Number ACTRN12616000924459. (Source: Acta Diabetologica)
Source: Acta Diabetologica - October 20, 2023 Category: Endocrinology Source Type: research

Clinical efficacy and safety of okra (Abelmoschus esculentus (L.) Moench) in type 2 diabetic patients: a randomized, double-blind, placebo-controlled, clinical trial
ConclusionsThe present study demonstrated that adjunctive consumption of okra, in type 2 diabetic patients with 1000 mg three times a day for three months, improves lipid profile, glycemic control, and chronic inflammation without any tangible adverse effects.Clinical Trial Registry: IRCT.Ir (IRCT20120112008712N2).https://www.irct.ir/trial/42042.Graphical abstract (Source: Acta Diabetologica)
Source: Acta Diabetologica - October 20, 2023 Category: Endocrinology Source Type: research

GCKR and ADIPOQ gene polymorphisms in women with gestational diabetes mellitus
ConclusionsThe genesGCKR andADIPOQ may be involved in the pathophysiology of GDM. (Source: Acta Diabetologica)
Source: Acta Diabetologica - October 20, 2023 Category: Endocrinology Source Type: research

Correction to: Clinical efficacy and safety of okra (Abelmoschus esculentus (L.) Moench) in type 2 diabetic patients: a randomized, double ‑blind, placebo‑controlled, clinical trial
(Source: Acta Diabetologica)
Source: Acta Diabetologica - October 20, 2023 Category: Endocrinology Source Type: research