Elevated serum levels of leukocyte cell-derived chemotaxin 2 are associated with the prevalence of metabolic syndrome
ConclusionsIncreased LECT2 levels were significantly and independently associated with the presence and severity of MetS, indicating that LECT2 could be used as a novel biomarker and clinical predictor of MetS.Graphical abstract (Source: Acta Diabetologica)
Source: Acta Diabetologica - February 22, 2024 Category: Endocrinology Source Type: research

Use of teplizumab in children and adolescents at risk of type 1 diabetes: perspectives of parents and caregivers from an Italian Pediatric Diabetes Center
ConclusionsOur findings underscore the necessity for comprehensive awareness campaigns spreading the current evidence concerning teplizumab in terms of both effectiveness and possible side effects. Additionally, our study reinforces the pivotal role of DKA prevention in successfully integrating disease-modifying treatments into clinical practice. (Source: Acta Diabetologica)
Source: Acta Diabetologica - February 21, 2024 Category: Endocrinology Source Type: research

Counterregulatory hormone and symptom responses to hypoglycaemia in people with type 1 diabetes, insulin-treated type 2 diabetes or without diabetes: the Hypo-RESOLVE hypoglycaemic clamp study
ConclusionAcute counterregulatory hormone and symptom responses to experimental hypoglycaemia are lower in people with type 1 diabetes than in those with long-standing insulin-treated type 2 diabetes and controls. (Source: Acta Diabetologica)
Source: Acta Diabetologica - February 20, 2024 Category: Endocrinology Source Type: research

OCT angiography 2023 update: focus on diabetic retinopathy
AbstractOptical coherence tomography angiography (OCTA) has become part of the clinical practice and its growing applications are in continuous development. Coherently with the growing concern about the human and economic cost of diabetes, diabetic retinopathy (DR) was the most popular topic for OCTA studies in the past year. The analysis of the literature reveals that applications of OCTA in DR are in continuous growth. In particular, ultrawide field (UWF) OCTA and artificial intelligence (AI) based on OCTA images are affirming as the new frontiers of scientific research in the field. Diagnostic accuracy of AI methods bas...
Source: Acta Diabetologica - February 20, 2024 Category: Endocrinology Source Type: research

Counterregulatory hormone and symptom responses to hypoglycaemia in people with type 1 diabetes, insulin-treated type 2 diabetes or without diabetes: the Hypo-RESOLVE hypoglycaemic clamp study
ConclusionAcute counterregulatory hormone and symptom responses to experimental hypoglycaemia are lower in people with type 1 diabetes than in those with long-standing insulin-treated type 2 diabetes and controls. (Source: Acta Diabetologica)
Source: Acta Diabetologica - February 20, 2024 Category: Endocrinology Source Type: research

OCT angiography 2023 update: focus on diabetic retinopathy
AbstractOptical coherence tomography angiography (OCTA) has become part of the clinical practice and its growing applications are in continuous development. Coherently with the growing concern about the human and economic cost of diabetes, diabetic retinopathy (DR) was the most popular topic for OCTA studies in the past year. The analysis of the literature reveals that applications of OCTA in DR are in continuous growth. In particular, ultrawide field (UWF) OCTA and artificial intelligence (AI) based on OCTA images are affirming as the new frontiers of scientific research in the field. Diagnostic accuracy of AI methods bas...
Source: Acta Diabetologica - February 20, 2024 Category: Endocrinology Source Type: research

Network analysis of depression, cognitive functions, and suicidal ideation in patients with diabetes: an epidemiological study in Iran
ConclusionThe findings suggest that suicide ideation is highly prevalent in patients with diabetes, and these symptoms should be carefully monitored in these patients. (Source: Acta Diabetologica)
Source: Acta Diabetologica - February 16, 2024 Category: Endocrinology Source Type: research

Sintilimab-induced autoimmune diabetes mellitus manifesting as diabetic ketoacidosis in a patient with advanced esophageal squamous cell carcinoma
(Source: Acta Diabetologica)
Source: Acta Diabetologica - February 9, 2024 Category: Endocrinology Source Type: research

Continuous improvement of quality of care in pediatric diabetes: the ISPED CARD clinical registry
ConclusionsThis report documents the feasibility of the ISPED CARD initiative and shows lights and shadows in the care provided. Improving care, increasing number of centers, and ameliorating data recording represent future challenges. (Source: Acta Diabetologica)
Source: Acta Diabetologica - February 8, 2024 Category: Endocrinology Source Type: research