Untangling pathways of risk factors associated with hypertension among dysglycemia adults in eastern China: a structural equation model approach
ConclusionAccordingly, we emphasized the importance of lifestyle intervention, mainly including obesity management, choosing healthy diets and decreasing smoking control, which may profoundly benefit this high-risk group among Chinese population. (Source: Acta Diabetologica)
Source: Acta Diabetologica - February 6, 2024 Category: Endocrinology Source Type: research

Association of pro-inflammatory cytokines, adipokines and hepatokine with incident diabetes in India: a nested case –control study within CARRS cohort
ConclusionsHigher TNF- α and MCP-1 levels and lower IL-6 were associated with higher risk of developing diabetes. Better understanding and potential methods of addressing these biomarkers, especially in relation to family history, are needed to address diabetes in South Asians. (Source: Acta Diabetologica)
Source: Acta Diabetologica - February 5, 2024 Category: Endocrinology Source Type: research

Impact of intravitreal anti-VEGF therapy on intraretinal microvascular abnormalities in proliferative diabetic retinopathy
(Source: Acta Diabetologica)
Source: Acta Diabetologica - February 1, 2024 Category: Endocrinology Source Type: research

Beware of buying online noninvasive continuous glucose monitoring devices: danger is just around the corner!
(Source: Acta Diabetologica)
Source: Acta Diabetologica - February 1, 2024 Category: Endocrinology Source Type: research

MIDD due to variants m.3243A   & gt;  G or m.12258C  & gt;  A not necessarily carries an increased risk of obstetric complications
(Source: Acta Diabetologica)
Source: Acta Diabetologica - February 1, 2024 Category: Endocrinology Source Type: research

Explaining improvement in diabetes distress: a longitudinal analysis of the predictive relevance of resilience and acceptance in people with type 1 diabetes
ConclusionsDiabetes acceptance is inversely related to diabetes distress, and increasing acceptance explained greater improvement in diabetes distress. These findings suggest that increasing diabetes acceptance may facilitate the reduction of diabetes distress. Treatment approaches targeting acceptance might be useful for the mental healthcare of people with type 1 diabetes and clinically elevated diabetes distress. (Source: Acta Diabetologica)
Source: Acta Diabetologica - February 1, 2024 Category: Endocrinology Source Type: research

Beware of buying online noninvasive continuous glucose monitoring devices: danger is just around the corner!
(Source: Acta Diabetologica)
Source: Acta Diabetologica - February 1, 2024 Category: Endocrinology Source Type: research

Impact of intravitreal anti-VEGF therapy on intraretinal microvascular abnormalities in proliferative diabetic retinopathy
(Source: Acta Diabetologica)
Source: Acta Diabetologica - February 1, 2024 Category: Endocrinology Source Type: research

Association of serum CTRP4 levels with vascular endothelial function in patients with type 2 diabetes mellitus: CTRP4 ameliorating inflammation, proliferation and migration in human umbilical vein endothelial cells
ConclusionsSerum CTRP4 concentrations were negatively associated with FMD. CTRP4 alleviated proliferation, migration and inflammation in HUVECs through the suppression of NF- κB and STAT3 signaling pathways. (Source: Acta Diabetologica)
Source: Acta Diabetologica - January 29, 2024 Category: Endocrinology Source Type: research

Association between a polygenic lipodystrophy genetic risk score and diabetes risk in the high prevalence Maltese population
ConclusionThis study consolidates the association between polygenic lipodystrophy risk alleles, metabolic syndrome parameters and T2DM risk particularly in normal-weight individuals. Our findings demonstrate that polygenic lipodystrophy risk alleles drive insulin resistance and diabetes risk independent of an increased BMI. (Source: Acta Diabetologica)
Source: Acta Diabetologica - January 27, 2024 Category: Endocrinology Source Type: research

LOX-1 regulation of H-type vascular endothelial cell regeneration in hyperglycemia
ConclusionsThe activation of LOX-1 and the inhibition of Notch/HIF-1 α/VEGF in THVECs are the main causes of DOP. These findings contribute to our understanding of the pathogenesis of DOP and offer a novel approach for preventing and treating osteoporosis. (Source: Acta Diabetologica)
Source: Acta Diabetologica - January 20, 2024 Category: Endocrinology Source Type: research

Obstetric complications in women with mitochondrial disease
(Source: Acta Diabetologica)
Source: Acta Diabetologica - January 18, 2024 Category: Endocrinology Source Type: research

Edible traditional Chinese medicines improve type 2 diabetes by modulating gut microbiotal metabolites
AbstractType 2 diabetes mellitus (T2DM) is a metabolic disorder with intricate pathogenic mechanisms. Despite the availability of various oral medications for controlling the condition, reports of poor glycemic control in type 2 diabetes persist, possibly involving unknown pathogenic mechanisms. In recent years, the gut microbiota have emerged as a highly promising target for T2DM treatment, with the metabolites produced by gut microbiota serving as crucial intermediaries connecting gut microbiota and strongly related to T2DM. Increasingly, traditional Chinese medicine is being considered to target the gut microbiota for T...
Source: Acta Diabetologica - January 16, 2024 Category: Endocrinology Source Type: research