Vaccines in cardiology, an underutilized strategy to reduce the residual cardiovascular risk
Arch Peru Cardiol Cir Cardiovasc. 2024 Mar 19;5(1):29-39. doi: 10.47487/apcyccv.v5i1.349. eCollection 2024 Jan-Mar.ABSTRACTCardiovascular diseases stand as the leading cause of mortality among adults globally. For decades, comprehensive evidence has underscored the correlation between infections, particularly those involving the respiratory system, and an elevated risk of cardiovascular and cerebrovascular events, as well as all-cause mortality. The mechanisms through which infections heighten cardiovascular events are intricate, encompassing immune system activation, systemic inflammation, hypercoagulable states, sympathe...
Source: Herpes - April 10, 2024 Category: Infectious Diseases Authors: Sebasti án García-Zamora Laura Pulido Source Type: research

Childhood vaccination coverage and regional differences in Swiss birth cohorts 2012-2021: Are we on track?
CONCLUSION: Full vaccination coverage in Swiss children is still below 90 % with many vaccinations administered delayed. Given regional differences, missed or delayed booster vaccinations, and differences in vaccine-specific acceptability, more effort may be needed to achieve national vaccination targets.PMID:38593195 | DOI:10.1016/j.vaccine.2023.10.043 (Source: Vaccine)
Source: Vaccine - April 9, 2024 Category: Allergy & Immunology Authors: Simeon J Z ürcher Andri Signorell Anja L échot-Huser Christoph Aebi Carola A Huber Source Type: research

A comparative analysis of knowledge, attitude, and practice (KAP) towards influenza and influenza vaccination among healthcare workers in Kyrgyzstan prior to and during the COVID-19 pandemic
CONCLUSION: Our investigation provides valuable insights into HCWs KAP concerning influenza vaccination in Kyrgyzstan, highlighting the need for targeted interventions addressing factors influencing vaccine acceptance. The study suggests policy implications, advocating for the revision of national strategies to strengthen capacity building for medical staff.PMID:38594119 | DOI:10.1016/j.vaccine.2024.04.008 (Source: Vaccine)
Source: Vaccine - April 9, 2024 Category: Allergy & Immunology Authors: Rakhat Akmatova Malembe S Ebama Sanjar Temirbekov Venera Alymkulova Dinara Otorbaeva Source Type: research

Adherence to Advisory Committee on Immunization Practices in diabetes mellitus patients in Saudi Arabia: A multicenter retrospective study
CONCLUSION: In Saudi Arabia, patients with DM showed higher vaccination rates for annual influenza and COVID-19 vaccines compared to other vaccinations such as herpes zoster, Tdap, pneumococcal, and HPV. Factors such as vaccine recommendations provided by family physicians or specialists, the site of care, income level, DM-related hospitalization history, residency site, HbA1c level, and health sector type can significantly influence the vaccination rate in patients with DM.PMID:38591075 | PMC:PMC10999047 | DOI:10.4239/wjd.v15.i3.440 (Source: Herpes)
Source: Herpes - April 9, 2024 Category: Infectious Diseases Authors: Saleh Fahad Alqifari Aya K Esmail Dalal M Alarifi Ghalya Y Alsuliman Maram M Alhati May R Mutlaq Mohammed Aldhaeefi Shaden A Alshuaibi Palanisamy Amirthalingam Abrar Abdallah Afaf S Wasel Heba R Hamad Shoroq Alamin Tasneem H Atia Tariq Alqahtani Source Type: research

Childhood vaccination coverage and regional differences in Swiss birth cohorts 2012-2021: Are we on track?
CONCLUSION: Full vaccination coverage in Swiss children is still below 90 % with many vaccinations administered delayed. Given regional differences, missed or delayed booster vaccinations, and differences in vaccine-specific acceptability, more effort may be needed to achieve national vaccination targets.PMID:38593195 | DOI:10.1016/j.vaccine.2023.10.043 (Source: Vaccine)
Source: Vaccine - April 9, 2024 Category: Allergy & Immunology Authors: Simeon J Z ürcher Andri Signorell Anja L échot-Huser Christoph Aebi Carola A Huber Source Type: research

A comparative analysis of knowledge, attitude, and practice (KAP) towards influenza and influenza vaccination among healthcare workers in Kyrgyzstan prior to and during the COVID-19 pandemic
CONCLUSION: Our investigation provides valuable insights into HCWs KAP concerning influenza vaccination in Kyrgyzstan, highlighting the need for targeted interventions addressing factors influencing vaccine acceptance. The study suggests policy implications, advocating for the revision of national strategies to strengthen capacity building for medical staff.PMID:38594119 | DOI:10.1016/j.vaccine.2024.04.008 (Source: Vaccine)
Source: Vaccine - April 9, 2024 Category: Allergy & Immunology Authors: Rakhat Akmatova Malembe S Ebama Sanjar Temirbekov Venera Alymkulova Dinara Otorbaeva Source Type: research

Expression of the SARS-CoV-2 receptor-binding domain by live attenuated influenza vaccine virus as a strategy for designing a bivalent vaccine against COVID-19 and influenza
Influenza and SARS-CoV-2 are two major respiratory pathogens that cocirculate in humans and cause serious illness with the potential to exacerbate disease in the event of co-infection. To develop a bivalent va... (Source: Virology Journal)
Source: Virology Journal - April 9, 2024 Category: Virology Authors: Ekaterina Stepanova, Irina Isakova-Sivak, Daria Mezhenskaya, Sergei Niskanen, Victoria Matyushenko, Ekaterina Bazhenova, Alexandra Rak, Pei Fong Wong, Polina Prokopenko, Tatiana Kotomina, Elena Krutikova, Sergei Legotskiy, Bogdan Neterebskii, Tatiana Ostr Tags: Research Source Type: research

Estimating averted illnesses from influenza vaccination for children and pregnant women - El Salvador, Panama, and Peru, 2011-2018
DISCUSSION: Influenza vaccination campaigns in El Salvador, Panama, and Peru conducted between 2011 and 2018 prevented hundreds to thousands of influenza-associated hospitalizations and illnesses in young children and pregnant women. Existing vaccination programs could prevent additional illnesses, using the same number of vaccines, by achieving the highest possible coverage within the first two months of an influenza vaccine campaign.PMID:38584055 | DOI:10.1016/j.vaccine.2024.04.007 (Source: Vaccine)
Source: Vaccine - April 7, 2024 Category: Allergy & Immunology Authors: Anna N Chard Chiedza Machingaidze Sergio Loayza Radhika Gharpure Francisco Nogareda Rosalba Gonz ález Rhina Dom ínguez Yeny O Tinoco Fatimah S Dawood Joseph Daniel Carreon Kathryn E Lafond Jorge Jara Eduardo Azziz-Baumgartner Vanessa Cozza Paula Couto M Source Type: research

Estimating averted illnesses from influenza vaccination for children and pregnant women - El Salvador, Panama, and Peru, 2011-2018
DISCUSSION: Influenza vaccination campaigns in El Salvador, Panama, and Peru conducted between 2011 and 2018 prevented hundreds to thousands of influenza-associated hospitalizations and illnesses in young children and pregnant women. Existing vaccination programs could prevent additional illnesses, using the same number of vaccines, by achieving the highest possible coverage within the first two months of an influenza vaccine campaign.PMID:38584055 | DOI:10.1016/j.vaccine.2024.04.007 (Source: Vaccine)
Source: Vaccine - April 7, 2024 Category: Allergy & Immunology Authors: Anna N Chard Chiedza Machingaidze Sergio Loayza Radhika Gharpure Francisco Nogareda Rosalba Gonz ález Rhina Dom ínguez Yeny O Tinoco Fatimah S Dawood Joseph Daniel Carreon Kathryn E Lafond Jorge Jara Eduardo Azziz-Baumgartner Vanessa Cozza Paula Couto M Source Type: research

Estimating averted illnesses from influenza vaccination for children and pregnant women - El Salvador, Panama, and Peru, 2011-2018
DISCUSSION: Influenza vaccination campaigns in El Salvador, Panama, and Peru conducted between 2011 and 2018 prevented hundreds to thousands of influenza-associated hospitalizations and illnesses in young children and pregnant women. Existing vaccination programs could prevent additional illnesses, using the same number of vaccines, by achieving the highest possible coverage within the first two months of an influenza vaccine campaign.PMID:38584055 | DOI:10.1016/j.vaccine.2024.04.007 (Source: Vaccine)
Source: Vaccine - April 7, 2024 Category: Allergy & Immunology Authors: Anna N Chard Chiedza Machingaidze Sergio Loayza Radhika Gharpure Francisco Nogareda Rosalba Gonz ález Rhina Dom ínguez Yeny O Tinoco Fatimah S Dawood Joseph Daniel Carreon Kathryn E Lafond Jorge Jara Eduardo Azziz-Baumgartner Vanessa Cozza Paula Couto M Source Type: research

Pilot-scale production of a highly efficacious and stable monoglycosylated influenza split virus vaccine
In conclusion, this study provides efficacy and safety profiles of IVR-190mg for further clinical study and shows that this vaccine without a glycan shield has great potential to be safe and protective against H1N1 variants.PMID:38582606 | DOI:10.1016/j.vaccine.2023.11.038 (Source: Vaccine)
Source: Vaccine - April 6, 2024 Category: Allergy & Immunology Authors: Chia-Ying Wu Shao-En Kao Yung-Chieh Tseng Jen-Tzu Hou Li-Yang Wu Juine-Ruey Chen Source Type: research

Immunogenicity and safety of adsorbed diphtheria-purified pertussis-tetanus-inactivated polio (Sabin strain)-Haemophilus type b conjugate combined vaccine (DPT-IPV-Hib) in healthy Japanese Infants  ≥ 2 and  & lt;  43 months of Age: A phase III, multicenter, active controlled, assessor-blinded, randomized, parallel-group study
CONCLUSION: A single-agent Gobik, the first DPT-IPV-Hib pentavalent vaccine approved in Japan, was confirmed to simultaneously provide primary and booster immunizations against Hib infection, pertussis, diphtheria, tetanus, and poliomyelitis and to have a preventive effect and safety comparable to concomitant vaccination with Hib (ActHIB®) and DPT-IPV quadrivalent vaccine (Tetrabik).PMID:38582691 | DOI:10.1016/j.vaccine.2023.03.077 (Source: Vaccine)
Source: Vaccine - April 6, 2024 Category: Allergy & Immunology Authors: Takashi Nakano Masumi Hasegawa Mai Endo Keiko Matsuda Hoshio Tamai Source Type: research

Detection of SARS-CoV-2-specific mucosal antibodies in saliva following concomitant COVID-19 and influenza vaccination in the ComFluCOV trial
Vaccine. 2024 Apr 4:S0264-410X(24)00367-0. doi: 10.1016/j.vaccine.2024.03.061. Online ahead of print.ABSTRACTThe ComFluCOV trial randomized 679 participants to receive an age-appropriate influenza vaccine, or placebo, alongside their second COVID-19 vaccine. Concomitant administration was shown to be safe, and to preserve systemic immune responses to both vaccines. Here we report on a secondary outcome of the trial investigating SARS-CoV-2-specific mucosal antibody responses. Anti-spike IgG and IgA levels in saliva were measured with in-house ELISAs. Concomitant administration of an influenza vaccine did not affect salivar...
Source: Vaccine - April 5, 2024 Category: Allergy & Immunology Authors: Holly E Baum Russell Thirard Alice Halliday Sarah Baos Amy C Thomas Rosie A Harris Elizabeth Oliver Lucy Culliford Benjamin Hitchings Rachel Todd Kapil Gupta Anu Goenka Adam Finn Chris A Rogers Rajeka Lazarus ComFluCOV Trial Group Source Type: research

Detection of SARS-CoV-2-specific mucosal antibodies in saliva following concomitant COVID-19 and influenza vaccination in the ComFluCOV trial
Vaccine. 2024 Apr 4:S0264-410X(24)00367-0. doi: 10.1016/j.vaccine.2024.03.061. Online ahead of print.ABSTRACTThe ComFluCOV trial randomized 679 participants to receive an age-appropriate influenza vaccine, or placebo, alongside their second COVID-19 vaccine. Concomitant administration was shown to be safe, and to preserve systemic immune responses to both vaccines. Here we report on a secondary outcome of the trial investigating SARS-CoV-2-specific mucosal antibody responses. Anti-spike IgG and IgA levels in saliva were measured with in-house ELISAs. Concomitant administration of an influenza vaccine did not affect salivar...
Source: Vaccine - April 5, 2024 Category: Allergy & Immunology Authors: Holly E Baum Russell Thirard Alice Halliday Sarah Baos Amy C Thomas Rosie A Harris Elizabeth Oliver Lucy Culliford Benjamin Hitchings Rachel Todd Kapil Gupta Anu Goenka Adam Finn Chris A Rogers Rajeka Lazarus ComFluCOV Trial Group Source Type: research

Parents and teachers ’ perspectives on a school-located influenza vaccination program: A pilot study in the Region of Murcia, Spain
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - April 4, 2024 Category: Allergy & Immunology Authors: Matilde Zornoza MorenoJaime P érez-MartínMarta Robles Mañuecoa Health Prevention and Protection Service, General Directorate of Public Health and Addictions, Health Council, Region de Murcia, Spainb Immunotherapy and Vaccines Unit, AstraZeneca Farmacé Source Type: research