Immunogenicity and safety of adsorbed diphtheria-purified pertussis-tetanus-inactivated polio (Sabin strain)-Haemophilus type b conjugate combined vaccine (DPT-IPV-Hib) in healthy Japanese Infants ≥ 2 and & lt; 43 months of Age: A phase III, multicenter, active controlled, assessor-blinded, randomized, parallel-group study
CONCLUSION: A single-agent Gobik, the first DPT-IPV-Hib pentavalent vaccine approved in Japan, was confirmed to simultaneously provide primary and booster immunizations against Hib infection, pertussis, diphtheria, tetanus, and poliomyelitis and to have a preventive effect and safety comparable to concomitant vaccination with Hib (ActHIB®) and DPT-IPV quadrivalent vaccine (Tetrabik).PMID:38582691 | DOI:10.1016/j.vaccine.2023.03.077
Source: Vaccine - Category: Allergy & Immunology Authors: Takashi Nakano Masumi Hasegawa Mai Endo Keiko Matsuda Hoshio Tamai Source Type: research