Hypertrophic Obstructive Cardiomyopathy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Septal Microsphere Embolization in Hypertrophic Obstructive Cardiomyopathy
Alcohol septal ablation is an established treatment for selected patients with hypertrophic cardiomyopathy and left ventricular outflow tract obstruction (LVOT). The safety and efficacy of septal microsphere embolization (SME) have not been studied. We conducted a retrospective analysis of SME procedures performed at our center from 2006 to 2021 using 75- µm microspheres. The primary end point was LVOT gradient reduction. Secondary outcomes included periprocedural mortality, conduction disturbances, access site complications, and duration of hospitalization. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - June 23, 2023 Category: Cardiology Authors: Emyal Alyaydin, Rolf Alexander J ánosi, Peter Luedike, Tienush Rassaf, Maria Papathanasiou Source Type: research

The lncRNA ADAMTS9-AS1/miR-185-5p/KAT7 ceRNA network inhibits cardiomyocyte hypertrophy in hypertrophic obstructive cardiomyopathy
This study was conducted to explore the role of lncRNA ADAMTS9 antisense RNA 1 (ADAMTS9-AS1) in HOCM-induced cardiomyocyte hypertrophy. The serum of HOCM patients was collected. AC16 cells were treated with isoproterenol (ISO) and transfected with oe-ADAMTS9-AS1 vector, miR-185-5p mimic, and lysine acetyltransferase 7 (KAT7) specific small interfering RNA. lncRNA ADAMTS9-AS1, miR-185-5p, KAT7, brain natriuretic peptide (BNP), and atrial natriuretic peptide (ANP) in the serum or cells were determine by qRT-PCR or Western blot assay. Cell surface area was observed by Texas Red-Phalloidin staining. Subcellular localization of...
Source: Biomed Res - May 31, 2023 Category: Research Authors: Bangrong Song Wei Li Xiaoyu Xu Haiming Dang Ran Dong Source Type: research

Outcomes of concomitant surgical ablation in patients undergoing surgical myectomy for hypertrophic obstructive cardiomyopathy: A systematic review and meta-analysis
Studies investigating the efficacy of concomitant surgical atrial fibrillation (AF) ablation in hypertrophic obstructive cardiomyopathy (HOCM) patients undergoing myectomy are scarce and limited in terms of sample size. We aim to summarize current outcomes of concomitant surgical AF ablation in HOCM patients undergoing surgical myectomy. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - May 30, 2023 Category: Cardiology Authors: Rohit K. Kharbanda, Nawin L. Ramdat Misier, Jef Van den Eynde, Sulayman El Mathari, Anton Tom šič, Meindert Palmen, Robert J.M. Klautz Source Type: research

Volume-outcome relationship in septal myectomy for hypertrophic obstructive cardiomyopathy
Septal myectomy is the gold standard treatment for refractory hypertrophic obstructive cardiomyopathy. The present study characterized the association of septal myectomy volume and cardiac surgery volume with outcomes after septal myectomy. (Source: Surgery)
Source: Surgery - May 23, 2023 Category: Surgery Authors: Joseph Hadaya, Arjun Verma, Yas Sanaiha, Richard J. Shemin, Peyman Benharash Source Type: research

Evaluation and implications of mitral regurgitation using cMRI in patients with hypertrophic cardiomyopathy
CONCLUSIONS: cMRI can accurately assess MR in patients with HCM, especially by using novel indicators, MRV and MRF respectively, along with LAV index and E/E' ratio. Severe MR, due to SAM, is more frequent in the obstructive form of HCM (HOCM). Also, the severity of MR is significantly associated with significantly associated with MRV, MRF, LAV index and E/E' ratio.PMID:37203824 | DOI:10.26355/eurrev_202305_32306 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - May 19, 2023 Category: Drugs & Pharmacology Authors: I D Muresan R Agoston A Serban S C D Mot S Costea A Zlibut R I Orzan B O Cojan-Minzat C Cionca D Horvat L Agoston-Coldea Source Type: research

Evaluation and implications of mitral regurgitation using cMRI in patients with hypertrophic cardiomyopathy
CONCLUSIONS: cMRI can accurately assess MR in patients with HCM, especially by using novel indicators, MRV and MRF respectively, along with LAV index and E/E' ratio. Severe MR, due to SAM, is more frequent in the obstructive form of HCM (HOCM). Also, the severity of MR is significantly associated with significantly associated with MRV, MRF, LAV index and E/E' ratio.PMID:37203824 | DOI:10.26355/eurrev_202305_32306 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - May 19, 2023 Category: Drugs & Pharmacology Authors: I D Muresan R Agoston A Serban S C D Mot S Costea A Zlibut R I Orzan B O Cojan-Minzat C Cionca D Horvat L Agoston-Coldea Source Type: research