Outcomes of cytoreductive operations for peritoneal carcinomatosis with or without liver cytoreduction in patients with small bowel neuroendocrine tumors
This study determines how much cytoreduction for small bowel neuroendocrine tumors with peritoneal carcinomatosis and liver metastases can be achieved and the corresponding survival benefits of different levels of clearance. (Source: Surgery)
Source: Surgery - May 27, 2020 Category: Surgery Authors: Sarah M. Wonn, Kristen E. Limbach, SuEllen J. Pommier, Anna N. Ratzlaff, E.J. Leon, Belinda H. McCully, Rodney F. Pommier Source Type: research

Routine histopathologic examination of the appendix after appendectomy for presumed appendicitis: Is it really necessary? A systematic review and meta-analysis
Owing to substantial costs and increasing interest in the nonoperative management of appendicitis, the necessity of routine histopathologic examination of appendectomy specimens is being questioned. The aim of this study was to determine whether routine histopathologic examination after appendectomy for suspected appendicitis should still be performed. (Source: Surgery)
Source: Surgery - May 27, 2020 Category: Surgery Authors: Vivian P. Bastiaenen, Wies M. Allema, Charlotte E.L. Klaver, Susan van Dieren, Lianne Koens, Pieter J. Tanis, Willem A. Bemelman Source Type: research

Lessons in flexibility from a general surgery program at the epicenter of the pandemic in New York City
New York City (NYC) evolved rapidly into the epicenter of the coronavirus disease 2019 (COVID-19) pandemic in the United States. Throughout the month of March, cases of COVID-19 infection in NYC increased rapidly with 41,771 positive patients and 1,096 mortalities as of March 31.1 Infection among health care workers strained hospital systems by limiting the number providers available for patient care as institutions become overwhelmed with COVID-19 patients. To preserve personal protective equipment (PPE), expand hospital bed capacity, and protect the safety of staff and patients, the Centers for Disease Control and Preven...
Source: Surgery - May 27, 2020 Category: Surgery Authors: Tamar B. Nobel, Michael Marin, Celia M. Divino Source Type: research

The Detrimental Effect of Covid-19 on Subspecialty Medical Education
As the Coronavirus pandemic stresses medical infrastructures, innovative healthcare recruitment efforts are being trialed. From reinstating licenses of retired physicians and nurses, to early medical school graduation and residency start dates – policies are being enacted to meet demand shortages. Undoubtably, healthcare providers at virus hotspots are short staffed, but is the demand equal among all specialties? Moreover, is this pandemic an unprecedented learning opportunity for trainees, or can it actually be a detriment? (Source: Surgery)
Source: Surgery - May 26, 2020 Category: Surgery Authors: Bartlomiej Imielski Source Type: research

Malignancy is in the eye of the beholder: Pathologic diagnosis of challenging follicular neoplasms in the era of noninvasive follicular thyroid neoplasms with papillary-like nuclear features and immunohistochemical and molecular adjuncts
Classification of thyroid follicular neoplasms can be challenging for pathologists. Introduction of noninvasive follicular thyroid neoplasms with papillary-like nuclear features, the utilization of immunohistochemistry, and molecular analysis are all thought to be valuable diagnostic adjuncts. Our aim was to determine whether interobserver variability for follicular neoplasms has improved since the application of these adjuncts. (Source: Surgery)
Source: Surgery - May 26, 2020 Category: Surgery Authors: Steven Craig, Moosa Khalil, Markus Eszlinger, Doha Itani, Martin Koebel, Konstantin Koro, Parham Minoo, Travis Ogilvie, Paul Stewardson, Carolin Teman, Bjoern Ziehr, Janice L. Pasieka Source Type: research

Risk factors for complications after cholecystectomy for common bile duct stones: An EAST multicenter study
We sought to prospectively identify risk factors for biliary complications and 30-day readmission after cholecystectomy for choledocholithiasis and gallstone pancreatitis across multiple US hospitals. (Source: Surgery)
Source: Surgery - May 26, 2020 Category: Surgery Authors: Brett M. Tracy, Cameron W. Paterson, Denise M. Torres, Katelyn Young, Beth R. Hochman, Martin D. Zielinski, Sigrid K. Burruss, Michelle B. Mulder, Daniel Dante Yeh, Rondi B. Gelbard, EAST Retained Common Bile Duct Stones Study Group Source Type: research

Thyroidectomy for euthyroid patients with Hashimoto thyroiditis and persisting symptoms: A cost-effectiveness analysis
This study evaluates the cost-effectiveness of total thyroidectomy for euthyroid patients who have Hashimoto thyroiditis with persistent symptoms. (Source: Surgery)
Source: Surgery - May 24, 2020 Category: Surgery Authors: Kelvin Memeh, Brian Ruhle, Tanaz Vaghaiwalla, Edwin Kaplan, Xavier Keutgen, Peter Angelos Source Type: research

Smoking and obesity are associated with increased readmission after elective repair of small primary ventral hernias: A nationwide database study
Smoking and obesity are well-known risk factors for surgical site infection, but it is unknown whether these factors influence outcomes after repair of small umbilical and epigastric hernias with defects ≤2 cm. The aim of this study was to evaluate whether smoking and obesity are associated with readmission, reoperation for complications, and recurrence rates after elective repair of small umbilical and epigastric hernias. (Source: Surgery)
Source: Surgery - May 24, 2020 Category: Surgery Authors: Nadia A. Henriksen, Thue Bisgaard, Frederik Helgstrand, Danish Hernia Database Source Type: research

Geriatric patients undergoing appendectomy have increased risk of intraoperative perforation and/or abscess
The number of geriatric patients is expected to grow 3-fold over the next 30 years, and as many as 50% of the surgeries done in the United States may occur in geriatric patients. Geriatric patients often have increased comorbidities and more often present in a delayed manner for acute appendicitis. The aim of this study was to evaluate outcomes between geriatric patients and younger patients undergoing appendectomy, hypothesizing that geriatric patients will have a higher risk of abscess and/or perforation, conversion to open surgery, postoperative intra-abdominal abscess, and 30-day readmission. (Source: Surgery)
Source: Surgery - May 24, 2020 Category: Surgery Authors: Shannon M. Fan, Areg Grigorian, Brian R. Smith, Catherine M. Kuza, Michael Lekawa, Sebastian D. Schubl, Ninh T. Nguyen, Jeffry Nahmias Source Type: research

Palliative care consults should be considered standard of care for patients presenting with ruptured abdominal aortic aneurysms
In the manuscript, “Palliative care is underutilized and impacts healthcare costs in ruptured abdominal aortic aneurysms,” by Dr Liu et al,1 the authors use administrative data from the Nationwide Inpatient Sample to evaluate the use and costs associated with palliative care consultations in patients presenting w ith ruptured abdominal aortic aneurysms (rAAA). They report that palliative care consultations were only obtained in 14% of patients and were more common among nonoperative patients and those undergoing open repair. (Source: Surgery)
Source: Surgery - May 24, 2020 Category: Surgery Authors: Caitlin W. Hicks Source Type: research

Cover 1(with editorial board)
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Source: Surgery - May 23, 2020 Category: Surgery Source Type: research

Information for readers
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Source: Surgery - May 23, 2020 Category: Surgery Source Type: research

Contents
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Source: Surgery - May 23, 2020 Category: Surgery Source Type: research

Information for authors
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Source: Surgery - May 23, 2020 Category: Surgery Source Type: research

Acknowledgments of peer reviewers
We would like to thank the reviewers listed below who contributed their time to review manuscripts for the past 6 months for Surgery. These individuals, as well as members of the Editorial Board, commit their time and careful consideration to ensure that published articles in Surgery reflect the highest standards of scholarship and relevance (Source: Surgery)
Source: Surgery - May 23, 2020 Category: Surgery Source Type: research

Effect of Transfer Status on Outcomes of Emergency General Surgery Patients
Transferred emergency general surgery (EGS) patients are a vulnerable, high acuity population. The outcomes of and health care utilization among transferred (TRAN) as compared to directly admitted (DA) patients have been studied primarily using single institution or hospital system data which limits generalizability. We evaluated these outcomes among EGS patients using a national database. (Source: Surgery)
Source: Surgery - May 23, 2020 Category: Surgery Authors: Jennifer L. Philip, Dou-Yan Yang, Xing Wang, Sara Fernandes-Taylor, Bret M. Hanlon, Jessica Schumacher, Megan C. Saucke, Jeffrey Havlena, Heena P. Santry, Angela M. Ingraham Source Type: research

Re: Chronic pain and risk for reoperation for recurrence after inguinal hernia repair using self-gripping mesh
We read with interest the report by Axman et  al1 entitled “Chronic pain and risk for reoperation for recurrence after inguinal hernia using self-gripping mesh.” We found this subject relevant because chronic pain after inguinal hernia repair remains one of the main postoperative complications than can cause chronic distress to patients. The authors reported a rate of 15% of patients with chronic pain after inguinal hernia repair, and although in their methods section they reported to have recorded how the surgeon handled the nerves, these data were not published. (Source: Surgery)
Source: Surgery - May 23, 2020 Category: Surgery Authors: Carolina Castro Ruiz, Erica Pavesi, Lara Ugoletti, Maurizio Zizzo, Valerio Annessi Source Type: research

Editors ’ introductory note
We have all been exposed to the horrors of the devastating coronavirus disease pandemic of 2019, and we have heard on the news and through social media the challenges that so many of our brave first responders, nurses, respiratory therapists, fellow physicians, families, and healthcare workers have suffered through. The following unsolicited editorial was written by a group of clinicians confronting the ethical problems they may face if a shortage of ventilators were to occur in their setting. Although not true ethicists as such, they represent the real world of dedicated, thoughtful, caring ethical surgeons. (Source: Surgery)
Source: Surgery - May 23, 2020 Category: Surgery Authors: Michael Sarr, Kevin Behrns Source Type: research

Primer for ICU Redeployment of the Non-Critical Care Surgeon: Insights from the Epicenter of the COVID-19 Pandemic
On April 6, 2020, our seven-person team of non-intensivists was redeployed to run a COVID-19 intensive care unit (ICU). (Source: Surgery)
Source: Surgery - May 23, 2020 Category: Surgery Authors: Danielle K. DePeralta, Andrew R. Hong, Charles Choy, John Wang, John P. Ricci, Brenda V. Marcano-Benfante, Aaron M. Lipskar Source Type: research

The management of surgical patients during the coronavirus dieases 2019 (COVID-19) pandemic
The coronavirus disease 2019 (COVID-19) pandemic has raised several issues regarding the management of surgical patients. The aim of the current study was to clarify the management of oncologic and surgical patients during the pandemic. (Source: Surgery)
Source: Surgery - May 22, 2020 Category: Surgery Authors: Gaya Spolverato, Giulia Capelli, Angelo Restivo, Quoc Riccardo Bao, Salvatore Pucciarelli, Timothy M. Pawlik, Alessandro Gronchi Source Type: research

Evaluating the quality of reporting of melanoma prediction models
This study evaluates the quality of reporting of prediction models using the Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis (TRIPOD) checklist. (Source: Surgery)
Source: Surgery - May 21, 2020 Category: Surgery Authors: Matthew Y. Jiang, Nathalie C. Dragnev, Sandra L. Wong Source Type: research

Response rates in metastatic neuroendocrine tumors receiving peptide receptor radionuclide therapy and implications for future treatment strategies
The objective of this study was to evaluate response rates among neuroendocrine tumors of different primaries and identify factors relevant to future treatment strategies. (Source: Surgery)
Source: Surgery - May 20, 2020 Category: Surgery Authors: Tanaz Vaghaiwalla, Brian Ruhle, Kelvin Memeh, Peter Angelos, Edwin Kaplan, Chih-Yi Liao, Blase Polite, Xavier Keutgen Source Type: research

Reflections on the COVID-19 epidemic: The first 30 days in one of New York ’s largest academic Departments of Surgery
Surgeons have always been on the front line for the management of many emergent and severe medical problems. Recent events have resulted in unprecedented challenges in the delivery of surgical care. The demands of the COVID-19 pandemic highlight the extraordinary resilience and adaptability of American healthcare providers and trainees while testing the capacity of the healthcare system. The courage and willingness of surgeons to participate in crisis management was demonstrated during the recent surge in New York City (NYC) - the epicenter of the COVID-19 pandemic in the United States. (Source: Surgery)
Source: Surgery - May 19, 2020 Category: Surgery Authors: Haejin In, Peter Muscarella, Erin Moran-Atkin, Robert E. Michler, W. Scott Melvin Source Type: research

Quality of life and occupational outcomes after laparoscopic Roux-en-Y gastric bypass surgery
Until now, no detailed long-term data regarding patients with declining quality of life or occupational status after laparoscopic Roux-en-Y gastric bypass surgery have been presented. The aim of this study was to evaluate the long-term effect of laparoscopic Roux-en-Y gastric bypass surgery on quality of life and occupational status. (Source: Surgery)
Source: Surgery - May 19, 2020 Category: Surgery Authors: Johanne Gormsen, Ismail G ögenur, Frederik Helgstrand Source Type: research

Clinical characteristics of emergency surgery patients-infected COVID-19 pneumonia in Wuhan, China
We aimed to investigate clinical symptom and epidemiological features of ESP-infected COVID-19 (Source: Surgery)
Source: Surgery - May 19, 2020 Category: Surgery Authors: Jinpeng Li, Rongfen Gao, Gaosong Wu, Xiaolin Wu, Zeming Liu, Hongjing Wang, Yihui Huang, Zhenyu Pan, Jincao Chen, Xiaohui Wu Source Type: research

Intraoperative application of inactivated Pseudomonas aeruginosa in patients undergoing lateral neck dissection for metastatic thyroid cancer: A randomized, parallel group, placebo-controlled trial
We hypothesize that the intraoperative, prophylactic application of Pseudomonas aeruginosa can decrease postoperative chylous fistula and enhance recovery after surgery in patients with thyroid cancer undergoing lateral neck lymph node dissection. (Source: Surgery)
Source: Surgery - May 18, 2020 Category: Surgery Authors: Li Genpeng, Song Jinen, Wei Tao, Li Zhihui, Gong Rixiang, Lei Jianyong, Zhu Jingqiang Source Type: research

National trends in ventral hernia repairs for patients with intra-abdominal metastases
Ventral hernias in patients with intra-abdominal metastases may not be addressed owing to other oncologic priorities, but they can affect quality of life and lead to sequelae necessitating an emergency operation. We compared the national trends and perioperative outcomes for elective and nonelective ventral hernia repairs for patients with intra-abdominal metastases. (Source: Surgery)
Source: Surgery - May 18, 2020 Category: Surgery Authors: Yun Song, Adrienne B. Shannon, Robert E. Roses, Douglas L. Fraker, Rachel R. Kelz, Giorgos C. Karakousis Source Type: research

Inside the courtroom: An analysis of malpractice litigation in gallbladder surgery
Cholecystectomy is one of the most commonly performed operations in the United States, yet it still carries up to a 6% risk of major morbidity. Lawsuits are a major source of emotional, financial, and personal stress for surgeons. We sought to characterize malpractice claims associated with gallbladder surgery as well as define contributing factors and costs with these claims. (Source: Surgery)
Source: Surgery - May 18, 2020 Category: Surgery Authors: Ayesha Farooq, Junu Bae, Daniel Rice, Amika Moro, Anghela Z. Paredes, Anna L. Crisp, Monica Windholtz, Kota Sahara, Diamantis I. Tsilimigras, J. Madison Hyer, Katiuscha Merath, Rittal Mehta, Efthimios Parasidis, Timothy M. Pawlik Source Type: research

Inhibition of a triggering receptor expressed on myeloid cells-1 (TREM-1) with an extracellular cold-inducible RNA-binding protein (eCIRP)-derived peptide protects mice from intestinal ischemia-reperfusion injury
Intestinal ischemia-reperfusion injury results in morbidity and mortality from both local injury and systemic inflammation and acute lung injury. Extracellular cold-inducible RNA-binding protein is a damage associated molecular pattern that fuels systemic inflammation and potentiates acute lung injury. We recently discovered a triggering receptor expressed on myeloid cells-1 serves as a novel receptor for extracellular cold-inducible RNA-binding protein. We developed a 7-aa peptide, named M3, derived from the cold-inducible RNA-binding protein, which interferes with cold-inducible RNA-binding protein ’s binding to a ...
Source: Surgery - May 18, 2020 Category: Surgery Authors: Naomi-Liza Denning, Monowar Aziz, Mahendar Ochani, Jose M. Prince, Ping Wang Source Type: research

Surgical Outcomes after Systematic Preoperative SARS-CoV-2 Screening
In the context of the COVID-19 pandemic this study showed feasibility and efficacy of systematic preoperative screening for SARS-CoV-2 by chest CT and RT-PCR on nasopharyngeal swabs. This screening strategy allowed performing safely the majority of scheduled oncological interventions. (Source: Surgery)
Source: Surgery - May 17, 2020 Category: Surgery Authors: Gilles Tilmans, Quentin Chenevas-Paule, Xavier Muller, Antoine Breton, Kayvan Mohkam, Christian Ducerf, Jean-Yves Mabrut, Micka ël Lesurtel Source Type: research

Adrenalectomy during pregnancy: A 15-year experience at a tertiary referral center
Adrenal lesions diagnosed during pregnancy remain rare, and their management is challenging because of maternal physiologic modifications, restricted imaging investigations, and contraindications to several treatments. Surgical issues of adrenalectomy during pregnancy and consequences on perinatal outcomes are poorly described. We therefore aimed to report maternal and fetal outcomes after adrenalectomy during pregnancy. (Source: Surgery)
Source: Surgery - May 17, 2020 Category: Surgery Authors: S ébastien Gaujoux, Élisabeth Hain, Louis Marcellin, Anne de Carbonnieres, François Goffinet, Jérôme Bertherat, Bertrand Dousset Source Type: research

Detailed perioperative risk among patients with extreme obesity undergoing nonbariatric general surgery
The obesity epidemic has spread rapidly across the United States. Although overweight and obese patients have a paradoxically lower risk for postoperative morbidity and mortality, the risks associated with extreme classes of obesity (morbid obesity, super obesity, and super-super obesity) have not been described. (Source: Surgery)
Source: Surgery - May 15, 2020 Category: Surgery Authors: Meera Gupta, Adam Dugan, Eduardo Chacon, Daniel L. Davenport, Malay B. Shah, Francesc Marti, J. Scott Roth, Andrew Bernard, Joseph B. Zwischenberger, Roberto Gedaly Source Type: research

Are narcotic pain medications necessary after discharge following thyroidectomy and parathyroidectomy?
The aim of this study was to determine whether patients undergoing thyroidectomy and parathyroidectomy have similar postoperative pain if managed with an opioid-sparing regimen versus an opioid-containing regimen. We hypothesized that an opioid-sparing regimen would provide equivalent analgesia. (Source: Surgery)
Source: Surgery - May 14, 2020 Category: Surgery Authors: Justin T. Brady, Angelina Dreimiller, Suzanne Miller-Spalding, Tiffany Gesang, Ashwini R. Sehgal, Christopher R. McHenry Source Type: research

Disparities in utilization of services for racial and ethnic minorities with hepatocellular carcinoma associated with hepatitis C
Hepatitis C affects racial minorities disproportionately and is greatest among the black population. The incidence of hepatocellular carcinoma has increased with the largest increase observed in black and Hispanic populations, but limited data remain on whether hepatitis C hepatocellular carcinoma in racial-ethnic minorities have the same utilization of services compared with the white population. (Source: Surgery)
Source: Surgery - May 12, 2020 Category: Surgery Authors: Aaron Kangas-Dick, Victor Gall, Patrick Hilden, Amber Turner, Alissa Greenbaum, Joanna Sesti, Subroto Paul, Darren Carpizo, Timothy Kennedy, Miral Sadaria Grandhi, H. Richard Alexander, Su Wang, Stuart Geffner, David August, Russell C. Langan Source Type: research

Safety of outpatient adrenalectomy across 3 minimally invasive approaches at 2 academic medical centers
Outpatient adrenalectomy has the potential to decrease costs, improve inpatient capacity, and decrease patient exposure to hospital-acquired conditions. Still, the practice has yet to be widely adopted and current studies demonstrating the safety of outpatient adrenalectomy are limited by sample size, extensive exclusion criteria, and no comparison to inpatient cases. We aimed to study the characteristics and safety of outpatient adrenalectomy using the largest such sample to date across 2 academic medical centers and 3 minimally invasive approaches. (Source: Surgery)
Source: Surgery - May 12, 2020 Category: Surgery Authors: Rajshri M. Gartland, Eva Fuentes, Jessica Fazendin, Zhi Ven Fong, Antonia Stephen, John R. Porterfield, Richard Hodin, Brenessa Lindeman Source Type: research

What is the impact of continuous neuromonitoring on the incidence of injury to the recurrent laryngeal nerve during total thyroidectomy?
Continuous intraoperative neuromonitoring may facilitate reversal of intraoperative injurious operative maneuvers in comparison with intermittent intraoperative neuromonitoring. The aim of this study was to evaluate the impact of the routine use of continuous intraoperative neuromonitoring on intraoperative injuries to the recurrent laryngeal nerve. (Source: Surgery)
Source: Surgery - May 12, 2020 Category: Surgery Authors: Florence Bihain, Claire Nomine-Criqui, L éa Demarquet, Claire Blanchard, Patrice Gallet, Phi-Linh Nguyen, Eric Mirallie, Laurent Brunaud Source Type: research

Does chest wall OIS or AIS predict outcomes? An analysis of 16,000 consecutive rib fractures
Chest wall injuries have serious clinical consequences. It is presumed higher severity of injury correlates with worse outcomes. The two most common chest wall injury severity scores, the Organ Injury Scale and Abbreviated Injury Scale, are based on expert opinion with unknown clinical endpoints. Aim: To determine if either OIS or AIS are associated with clinical outcomes. (Source: Surgery)
Source: Surgery - May 12, 2020 Category: Surgery Authors: Jennifer E. Baker, D. Anderson Millar, Victor Heh, Michael D. Goodman, Timothy A. Pritts, Christopher Janowak Source Type: research

Outcomes of abdominal wall reconstruction in patients with the combination of complex midline and lateral incisional hernias
The best treatment for repair of complex concomitant incisional hernias of the midline and lateral abdominal wall is not known. The importance of this multicenter study is to describe our results based on patient-reported outcomes using a posterior component separation in these difficult hernia repairs. (Source: Surgery)
Source: Surgery - May 11, 2020 Category: Surgery Authors: Joaqu ín Manuel Muñoz Rodríguez, Javier López-Monclús, Carlos San Miguel Méndez, Marina Pérez-Flecha González, Álvaro Robin Valle de Lersundi, Luis Alberto Blázquez Hernando, Diego Curcurullo, Esteban García Hernández, Víctor Sánchez Turrió Source Type: research

Role of Interprofessional Teams in Emergency General Surgery Patient Outcomes
In response to duty hour restrictions, hospitals expanded residency programs and added advanced practice providers (APPs). We sought to determine if type of clinical support was associated with emergency general surgery (EGS) outcomes. (Source: Surgery)
Source: Surgery - May 11, 2020 Category: Surgery Authors: Wendelyn M. Oslock, Kevin B. Ricci, Angela M. Ingraham, Amy P. Rushing, Holly E. Baselice, Anghela Z. Paredes, Victor K. Heh, Cindy A. Byrd, Scott A. Strassels, Heena P. Santry Source Type: research

Variation in value among hospitals performing complex cancer operations
While variation in outcomes has driven centralization of complex cancer surgery, variation in cost and value remains unexplored. We evaluated outcomes relative to cost among hospitals performing esophageal and pancreatic resection for cancer. (Source: Surgery)
Source: Surgery - May 11, 2020 Category: Surgery Authors: Adrian Diaz, Anghela Z. Paredes, J. Madison Hyer, Timothy M. Pawlik Source Type: research

An incarcerated inguinal hernia with unusual content
A 74-year-old man presented to the surgical clinic with a 6-month history of epigastric pain, dysphagia, and weight loss of more than 15 kg. His medical history included active smoking and moderate alcohol consumption, and he reported the appearance of an inguinal hernia for several years. Clinical examination revealed a large left inguinoscrotal hernia that was irreducible. In view of the atypical symptoms, an upper gastrointestinal series and an abdominal computed tomography were planned and revealed gastroptosis with incarceration of the stomach in the hernia (Fig 1). (Source: Surgery)
Source: Surgery - May 11, 2020 Category: Surgery Authors: David Martin, Luca Di Mare Source Type: research

Symptom relief and quality of life after combined partial hepatectomy and cyst fenestration in highly symptomatic polycystic liver disease
Polycystic liver disease can cause severe symptomatic hepatomegaly. Combined partial hepatectomy and cyst fenestration can be performed to reduce liver volume and symptom burden. We aimed to assess change in symptom relief and quality of life 6 months after partial hepatectomy and cyst fenestration in polycystic liver disease patients. (Source: Surgery)
Source: Surgery - May 10, 2020 Category: Surgery Authors: Lucas H.P. Bernts, Myrte K. Neijenhuis, Marie E. Edwards, Jeff A. Sloan, Jenna Fischer, Rory L. Smoot, David M. Nagorney, Joost P.H. Drenth, Marie C. Hogan Source Type: research

Impact of surgery versus medical management on cardiovascular manifestations in Graves disease
Graves disease is well known to have multiple adverse effects on the cardiovascular system. We compared the cardiovascular outcomes after surgical intervention versus medical treatment in patients with Graves disease. (Source: Surgery)
Source: Surgery - May 10, 2020 Category: Surgery Authors: Ahmed Elnahla, Abdallah S. Attia, Helmi S. Khadra, Ruhul Munshi, Hosam Shalaby, Grace S. Lee, Emad Kandil Source Type: research

Intraoperative parathyroid hormone (IOPTH) assay might be better than the second-generation assay in parathyroidectomy for primary hyperparathyroidism
It is unclear whether the third-generation intraoperative parathyroid hormone assay can improve surgical outcomes over second-generation assay in primary hyperparathyroidism. We aimed to compare the rate of decrease and diagnostic accuracy between the two assays after parathyroid adenoma excision. (Source: Surgery)
Source: Surgery - May 10, 2020 Category: Surgery Authors: Brian Hung-Hin Lang, Matrix Man Him Fung Source Type: research

Reallocating Ventilators During the COVID-19 Pandemic: Is it Ethical?
The unprecedented COVID-19 pandemic has challenged our society to evaluate our core values and ethics. In a crisis like none other, health care facilities and physicians are now facing shortages of ventilators, beds, and even basic personal protective equipment. Many physicians are already facing a profound ethical dilemma: how to allocate these resources during shortages1-4; with some hospitals, states and countries even having to establish policies on which groups of patients to prioritize in providing lifesaving treatment during the COVID-19 crisis. (Source: Surgery)
Source: Surgery - May 7, 2020 Category: Surgery Authors: Quyen Chu, Ricardo Correa, Tracey L. Henry, Kyle A. McGregor, Hanni Stoklosa, Loren Robinson, Sachin Jha, Alagappan Annamalai, Benson S. Hsu, Rohit Gupta, Desmond Upton Patton, Lisa A. Moreno-Walton, Christine Butts, Christy Chai, SreyRam Kuy Source Type: research

Commentary
This is a timely and important subject worthy of discussion. Although the Covid-19 era has forced scarce medical resource allocation to the front of our consciousness, it has always been with us, and will still be with us when Covid-19 has been vanquished. (Source: Surgery)
Source: Surgery - May 7, 2020 Category: Surgery Authors: Marc D. Basson Source Type: research

Shock after thoracic drainage
An 83-year-old patient with a left pulmonary adenocarcinoma was admitted to the hospital for ipsilateral stage 1 empyema. An ultrasound-guided drainage with a 14 Fr pigtail catheter was performed. In the hours after the drainage, she presented a state of shock with a hemoglobin drop of 30g/L. Initial hemodynamic instability quickly responded to intravenous saline perfusion. (Source: Surgery)
Source: Surgery - May 6, 2020 Category: Surgery Authors: Joe Khallouf, Styliani Mantziari, Emilie Uldry Source Type: research

Small bowel ischemia and SARS-CoV-2 infection: an underdiagnosed distinct clinical entity
Gastrointestinal symptoms have been described in up to 39% of SARS-CoV-2 infected patients (1). Evidence for SARS-CoV-2 gastrointestinal infection was already demonstrated in a series of 73 patients, with 53% of patients tested positive for SARS-CoV-2 RNA in stool, possibly by the mediation through the viral host receptor ACE2, which stained positive in the cytoplasm of gastrointestinal epithelial cells (2). This data suggests that the virus can actively replicate in the bowel, but the computed tomography (CT) rendering of the gastrointestinal infection and its significance for the natural history of the disease remain unc...
Source: Surgery - May 4, 2020 Category: Surgery Authors: Mihaela Ignat, Guillaume Philouze, Lucie Aussenac-Belle, Vanina Faucher, Olivier Collange, Didier Mutter, Patrick Pessaux Source Type: research

Tumor-specific near-infrared nanobody probe rapidly labels tumors in an orthotopic mouse model of pancreatic cancer
Nanobodies, derived from camelid antibodies made of only heavy chains, are the smallest, biologic, antigen-binding fragments (~15kDa) with faster pharmacokinetics and better tumor penetration efficiency than standard antibodies. The present study evaluates the efficacy of a fluorescent, anti-carcinoembryonic antigen (CEA) nanobody for rapid tumor labeling in an orthotopic mouse model of pancreatic cancer. (Source: Surgery)
Source: Surgery - May 3, 2020 Category: Surgery Authors: Thinzar M. Lwin, Sophie Hernot, Hannah Hollandsworth, Siamak Amirfakhri, Filemoni Filemoni, Pieterjan Debie, Robert M. Hoffman, Michael Bouvet Source Type: research

Gilbert double layer graft method for groin hernias in patients with ascites: A retrospective study of 81 patients
Patients with ascites undergoing an inguinal hernia repair have an increased rate of both morbidity and mortality compared with those without ascites, leading to controversy regarding the indications for herniorrhaphy in patients with ascites. The purpose of this retrospective study was to analyze the clinical results of a tension-free herniorrhaphy using the Gilbert approach in 81 patients with an inguinal hernia complicated by the presence of ascites. (Source: Surgery)
Source: Surgery - May 3, 2020 Category: Surgery Authors: Shiwei Yang, Yongyang Yu, Yong Wang, Wenqin Luo, Bing Wu, Wenzhang Lei, Zongguang Zhou Source Type: research