Validation of index-based IWATE criteria as an improved difficulty scoring system for laparoscopic liver resection
The original difficulty scoring system was revised after discussion at the 2nd International Consensus Conference on Laparoscopic Liver Resection held in Morioka (Iwate Prefecture) in Japan and renamed the IWATE criteria (a 4-level classification system involving 6 preoperative factors). We used Japanese and French cohorts to validate the IWATE criteria by evaluating their association with the procedure-based difficulty classification proposed by the Institut Mutualiste Montsouris. (Source: Surgery)
Source: Surgery - November 13, 2018 Category: Surgery Authors: Shogo Tanaka, Yoshikuni Kawaguchi, Shoji Kubo, Akishige Kanazawa, Yutaka Takeda, Fumitoshi Hirokawa, Hiroyuki Nitta, Takayoshi Nakajima, Takashi Kaizu, Masaki Kaibori, Toru Kojima, Yuichiro Otsuka, David Fuks, Kiyoshi Hasegawa, Norihiro Kokudo, Hironori K Source Type: research

Innovative surgical guidance for label-free real-time parathyroid identification
Difficulty in identifying the parathyroid gland during neck operations can lead to accidental parathyroid gland excisions and postsurgical hypocalcemia. A clinical prototype called as PTeye was developed to guide parathyroid gland identification using a fiber-optic probe that detects near-infrared autofluorescence from parathyroid glands as operating room lights remain on. An Overlay Tissue Imaging System was designed concurrently to detect near-infrared autofluorescence and project visible light precisely onto parathyroid gland location. (Source: Surgery)
Source: Surgery - November 12, 2018 Category: Surgery Authors: Giju Thomas, Melanie A. McWade, John Q. Nguyen, Melinda E. Sanders, James T. Broome, Naira Baregamian, Carmen C. Sol órzano, Anita Mahadevan-Jansen Source Type: research

Building community resilience: A scalable model for hemorrhage-control training at a mass gathering site, using the RE-AIM framework
This study evaluates the implementation of American College of Surgeons Bleeding Control training at a National Football League stadium as a prospective model for general mass gathering site implementation. (Source: Surgery)
Source: Surgery - November 10, 2018 Category: Surgery Authors: Muhammad Ali Chaudhary, Justin McCarty, Samir Shah, Zain Hashmi, Edward Caterson, Scott Goldberg, Craig Goolsby, Adil Haider, Eric Goralnick Source Type: research

Disagreement: Should the duration of primary hyperparathyroidism impact guidelines for evaluation and treatment?
We reviewed the article by Randle and Lee.1 We agree thoroughly with the authors that greater duration of primary hyperparathyroidism (PHPT) should prompt us to evaluate end-organ involvement even in normocalcemic or asymptomatic PHPT.2,3 But we believe that the treatment planning should not be tailored according to the duration of PHPT. We have the following comments to support our disagreement with the authors. (Source: Surgery)
Source: Surgery - November 10, 2018 Category: Surgery Authors: Kavindra Singh, Manish Khattar, Chitresh Kumar Source Type: research

Mortality and morbidity after pancreatoduodenectomy in patients undergoing hemodialysis: Analysis using a national inpatient database
Whether patients undergoing hemodialysis have greater risks of mortality and morbidity after pancreatoduodenectomy remains unknown. (Source: Surgery)
Source: Surgery - November 10, 2018 Category: Surgery Authors: Hiroji Shinkawa, Hideo Yasunaga, Kiyoshi Hasegawa, Hiroki Matsui, Nobuaki Michihata, Kiyohide Fushimi, Norihiro Kokudo Source Type: research

End-organ effects of primary hyperparathyroidism: A population-based study
Patients with primary hyperparathyroidism are at risk for skeletal and renal end-organ damage. (Source: Surgery)
Source: Surgery - November 9, 2018 Category: Surgery Authors: Yasmine Assadipour, Hui Zhou, Eric J. Kuo, Philip I. Haigh, Annette L. Adams, Michael W. Yeh Source Type: research

NIFT-P: Are they indolent tumors? Results of a multi-institutional study
Encapsulated follicular variant of papillary thyroid carcinoma has recently been reclassified as noninvasive follicular thyroid neoplasm with papillary-like nuclear features on the basis of its highly indolent behavior, as proposed by an international group of experienced thyroid pathologists. (Source: Surgery)
Source: Surgery - November 9, 2018 Category: Surgery Authors: Nathalie Chereau, T. Greilsamer, Eric Miralli é, S.M. Sadowski, M. Pusztaszeri, Frederic Triponez, G. Baud, Francois Pattou, N. Christou, M. Mathonnet, Laurent Brunaud, N. Santucci, Pierre Goudet, C. Guérin, Frédéric Sebag, G. Donatini, Jean-Louis Kra Source Type: research

Characterization of somatostatin receptors (SSTRs) expression and antiproliferative effect of somatostatin analogues in aggressive thyroid cancers
This study seeks to characterize somatostatin receptor expression in follicular thyroid cancer and anaplastic thyroid cancer and to assess the effects of somatostatin analogues. (Source: Surgery)
Source: Surgery - November 8, 2018 Category: Surgery Authors: Danilea M Carmona Matos, Samuel Jang, Baraa Hijaz, Alex W Chang, Ricardo V Lloyd, Herbert Chen, Renata Jaskula-Sztul Source Type: research

Unilateral benign multinodular versus solitary goiter: Long-term contralateral reoperation rates after lobectomy
Few long-term studies define the appropriate extent of surgery and recurrence rates for unilateral multinodular goiter. We compared the rate and time to reoperation in patients with multinodular goiter who underwent lobectomy to that of patients with benign solitary nodule. (Source: Surgery)
Source: Surgery - November 8, 2018 Category: Surgery Authors: Beatriz de Rienzo-Madero, John P Sabra, Elise Gand, Gianluca Donatini, Jean-Louis Kraimps Source Type: research

Stage migration with the new American Joint Committee on Cancer (AJCC) staging system (8th edition) for differentiated thyroid cancer
Tumor, node, and metastasis staging in thyroid carcinoma is important for assessing prognosis. However, patients with stage III or IV disease have an overall survival rate of 90%. The change to 55 years of age as the cutoff will create stage migration and many patients will be downstaged. (Source: Surgery)
Source: Surgery - November 8, 2018 Category: Surgery Authors: Ashok R. Shaha, Jocelyn C. Migliacci, Iain J. Nixon, Laura Y. Wang, Richard J. Wong, Luc G.T. Morris, Snehal G. Patel, Jatin P. Shah, R. Michael Tuttle, Ian Ganly Source Type: research

68Gallium-DOTATATE positron emission tomography –computed tomography (PET CT) changes management in a majority of patients with neuroendocrine tumors
68Gallium-DOTATATE positron emission tomography –computed tomography (PET CT) has shown superior accuracy in detecting grade 1 and 2 neuroendocrine tumors over previous imaging modalities and was recently included in National Comprehensive Cancer Network guidelines. It remains unclear which patients benefit most from this imaging modality. We t herefore reviewed our initial experience with 68Gallium-DOTATATE PET CT to evaluate its usefulness in diagnosing, staging, and surveilling neuroendocrine tumors. (Source: Surgery)
Source: Surgery - November 8, 2018 Category: Surgery Authors: John F. Tierney, Cory Kosche, Erik Schadde, Amjad Ali, Sumeet Virmani, Sam G. Pappas, Jennifer Poirier, Xavier M. Keutgen Source Type: research

Parathyroidectomy versus Cinacalcet in the Management of Tertiary Hyperparathyroidism: Surgery Improves Renal Transplant Allograft Survival
Renal transplant allograft function in patients with tertiary hyperparathyroidism who are treated with cinacalcet versus parathyroidectomy remains unclear. (Source: Surgery)
Source: Surgery - November 8, 2018 Category: Surgery Authors: Brendan M. Finnerty, Tyler W. Chan, Gregory Jones, Tarek Khader, Maureen Moore, Katherine D. Gray, Toni Beninato, Anthony C. Watkins, Rasa Zarnegar, Thomas J. Fahey Source Type: research

A prospective study of the pathophysiology of carcinoid crisis
Sudden massive release of serotonin, histamine, kallikrein, and bradykinin is postulated to cause an intraoperative carcinoid crisis. The exact roles of each of these possible agents, however, remain unknown. Optimal treatment will require an improved understanding of the pathophysiology of the carcinoid crisis. (Source: Surgery)
Source: Surgery - November 8, 2018 Category: Surgery Authors: Mary E. Condron, Nora E. Jameson, Kristen E. Limbach, Ann E. Bingham, Valerie A. Sera, Ryan B. Anderson, Katie J. Schenning, Shaun Yockelson, Izumi Harukuni, Edward A. Kahl, Elizabeth Dewey, SuEllen J. Pommier, Rodney F. Pommier Source Type: research

The association between the ultrasonography TIRADS classification system and surgical pathology among indeterminate thyroid nodules
A high proportion of cytologically indeterminate, Afirma-suspicious thyroid nodules are benign. The Thyroid Imaging Reporting and Data System was proposed by the American College of Radiology in 2015 to determine appropriate management of thyroid nodules in a standardized fashion. Our aim was to determine the diagnostic value of the Thyroid Imaging Reporting and Data System in cytologically indeterminate and Afirma-suspicious nodules. (Source: Surgery)
Source: Surgery - November 8, 2018 Category: Surgery Authors: Zeyad T Sahli, Farah Karipineni, Jen-Fan Hang, Joseph K Canner, Aarti Mathur, Jason D Prescott, Sheila Sheth, Syed Z Ali, Martha A Zeiger Source Type: research

The effect of total thyroidectomy on the recovery of bone mineral density in subjects with hyperthyroidism
Although hyperthyroidism is associated with high turnover osteopenia and its recovery after treatment, the extent of recovery with different forms of therapy remains controversial. This prospective study evaluated the bone mineral density in thyrotoxic subjects undergoing total thyroidectomy and 131I radioactive iodine therapy. (Source: Surgery)
Source: Surgery - November 8, 2018 Category: Surgery Authors: Poongkodi Karunakaran, Chandrasekaran Maharajan, Rajasekaran Chockalingam, Premkumar Asokumar, Kamaleswaran Koramadai Karuppusamy, Vijay Sadasivam Source Type: research

Keeping primary aldosteronism in mind: Deficiencies in screening at-risk hypertensives
Primary aldosteronism is a common but underdiagnosed cause of hypertension. Patients with this disorder have worse morbidity compared with those with essential hypertension, but with timely diagnosis and appropriate intervention these patients are potentially cured and may have reversal of target organ damage. The goal of this study was to determine if hypertensive patients considered high risk were checked for primary aldosteronism. (Source: Surgery)
Source: Surgery - November 8, 2018 Category: Surgery Authors: Brian C. Ruhle, Michael G. White, Salman Alsafran, Edwin L. Kaplan, Peter Angelos, Raymon H. Grogan Source Type: research

Are PROMs ideally suited for most common endocrine surgical patients and procedures?
Patient-Reported Outcome Measures (PROMs) represent a powerful tool to help patients and physicians understand the impact of their disease, as well as the proposed therapeutic options. The National Institutes of Health has funded the development of numerous surveys for patient self-reported measures of physical, mental, and social health.1 Whereas many of the more basic surveys may focus on more general feelings of mental and physical health, additional tools exist to identify specific symptoms, function, mental health issues, or social well-being. (Source: Surgery)
Source: Surgery - November 8, 2018 Category: Surgery Authors: Sarah C. Oltmann, Fiemu E. Nwariaku Source Type: research

High prevalence of chronic kidney disease in patients with multiple endocrine neoplasia type 1 and improved kidney function after parathyroidectomy
Because chronic kidney disease is an important comorbidity associated with primary hyperparathyroidism, we sought to evaluate the prevalence of chronic kidney disease and effects of parathyroidectomy on kidney function in patients with multiple endocrine neoplasia type 1 –associated primary hyperparathyroidism. (Source: Surgery)
Source: Surgery - November 7, 2018 Category: Surgery Authors: Patience Green, Jonathan Zagzag, Dhaval Patel, Lee S. Weinstein, William F. Simonds, Jenny Blau, Stephen Marx, Electron Kebebew, Nancy Perrier, Naris Nilubol Source Type: research

Total versus subtotal parathyroidectomy for secondary hyperparathyroidism
It remains unclear whether total or subtotal parathyroidectomy for secondary hyperparathyroidism yields the best outcomes. We investigated mortality, cardiovascular events, hip fracture, and recurrent parathyroidectomy after total versus subtotal parathyroidectomy in patients on renal replacement therapy. (Source: Surgery)
Source: Surgery - November 6, 2018 Category: Surgery Authors: Elin Isaksson, Kerstin Ivarsson, Shahriar Akaberi, Andreas Muth, Karl-G öran Prütz, Naomi Clyne, Gunnar Sterner, Martin Almquist Source Type: research

Primary aldosteronism with nonlocalizing imaging
Unilateral primary aldosteronism is surgically curable. The goal of this study was to examine outcomes based on preoperative imaging findings. (Source: Surgery)
Source: Surgery - November 6, 2018 Category: Surgery Authors: Heather Wachtel, Sonia Bhandari, Robert E. Roses, Debbie L. Cohen, Scott O. Trerotola, Douglas L. Fraker Source Type: research

Over expression of DNA damage and cell cycle dependent proteins are associated with poor survival in patients with adrenocortical carcinoma
Adrenocortical carcinoma is a rare and aggressive malignancy with poor survival. With limited treatment options and high risk of relapse, identifying improved targets and therapies for adrenocortical carcinoma is important. We hypothesized that analysis of the database of The Cancer Genome Atlas could identify important novel biomarkers for improved therapeutic targeting of adrenocortical carcinoma. (Source: Surgery)
Source: Surgery - November 6, 2018 Category: Surgery Authors: Chitra Subramanian, Mark S Cohen Source Type: research

Expression of programmed death ligand 1 and 2 in adrenocortical cancer tissues: An exploratory study
In this study, we investigated programmed death ligand 1 and 2 expression in adrenocortical carcinoma to determine the potential usefulness of checkpoint inhibitors in these malignant neoplasms. (Source: Surgery)
Source: Surgery - November 6, 2018 Category: Surgery Authors: John F. Tierney, Alyx Vogle, Jennifer Poirier, Irene M. Min, Brendan Finnerty, Rasa Zarnegar, Sam G. Pappas, Theresa Scognamiglio, Ritu Ghai, Paolo Gattuso, Thomas J. Fahey, Xavier M. Keutgen Source Type: research

Preoperative calcitriol reduces postoperative intravenous calcium requirements and length of stay in parathyroidectomy for renal-origin hyperparathyroidism
Patients undergoing subtotal parathyroidectomy for renal-origin hyperparathyroidism often develop postoperative hypocalcemia, requiring calcitriol and intravenous calcium (Postop-IVCa). We hypothesized that in subtotal parathyroidectomy for renal-origin hyperparathyroidism, preoperative calcitriol treatment reduces the use of postoperative administration of intravenous calcium. (Source: Surgery)
Source: Surgery - November 6, 2018 Category: Surgery Authors: Salman Alsafran, Scott K. Sherman, Fadi S. Dahdaleh, Brian Ruhle, Frederic Mercier, Edwin L. Kaplan, Peter Angelos, Raymon H. Grogan Source Type: research

Evacuation of postoperative hematomas after thyroid and parathyroid surgery: An analysis of the CESQIP Database
A feared complication after thyroid and parathyroid operations is postoperative hematoma that threatens the airway. The aim of this study was to identify factors associated with postoperative hematoma. (Source: Surgery)
Source: Surgery - November 6, 2018 Category: Surgery Authors: Stephanie D. Talutis, F. Thurston Drake, Teviah Sachs, Sowmya R. Rao, David McAneny Source Type: research

Treatment strategy of end-stage renal disease related hyperparathyroidism before, during, and after the era of calcimimetics
Since 2004, end-stage renal disease related hyperparathyroidism patients are treated mainly with cinacalcet, which ceased to be subsidized through the Australian Pharmaceutical Benefits Scheme in 2015. We aimed to investigate the impact of these changes on the treatment strategy in the Australian end-stage renal disease population. (Source: Surgery)
Source: Surgery - November 6, 2018 Category: Surgery Authors: Willemijn Y. van der Plas, Anton F. Engelsman, Marille Umakanthan, Amanda Mather, Stan B. Sidhu, Leigh W. Delbridge, Carol Pollock, David Waugh, Mark S. Sywak, Schelto Kruijff Source Type: research

Natural history of papillary thyroid microcarcinoma: Kinetic analyses on tumor volume during active surveillance and before presentation
We report on the growth of papillary microcarcinoma during active surveillance and before clinical presentation. (Source: Surgery)
Source: Surgery - November 6, 2018 Category: Surgery Authors: Akira Miyauchi, Takumi Kudo, Yasuhiro Ito, Hitomi Oda, Masatoshi Yamamoto, Hisanori Sasai, Takuya Higashiyama, Hiroo Masuoka, Mitsuhiro Fukushima, Minoru Kihara, Akihiro Miya Source Type: research

The optimal dosing scheme for levothyroxine after thyroidectomy: A comprehensive comparison and evaluation
The objectives of this study were to review the literature for existing levothyroxine dosing schemes and compare estimation accuracies with novel schemes developed with machine learning. (Source: Surgery)
Source: Surgery - November 6, 2018 Category: Surgery Authors: Nick A. Zaborek, Andy Cheng, Joseph R. Imbus, Kristin L. Long, Susan C. Pitt, Rebecca S. Sippel, David F. Schneider Source Type: research

One Way to Approach Accessing and Educating the Community for Delivery of Health Care to Attempt to Address the Disparity of Health Care Delivery
Providing access and empowering medical education to underserved, at-risk populations remains a substantial challenge. We have made great strides in the diagnosis, treatment, and outcomes in a number of troubling health problems, yet huge gaps remain in populations who are isolated by racial, economic, educational, or geographic characteristics. (Source: Surgery)
Source: Surgery - November 6, 2018 Category: Surgery Authors: Scott A. Dulchavsky Source Type: research

Regarding: A clinical prediction model to estimate the metastatic potential of pheochromocytoma/paraganglioma: ASES score
It was quite interesting to read the article by Cho et al1 in which the authors have tried to create a clinical prediction model to estimate the metastatic potential of pheochromocytoma/paragangliomas (PPGL). This indeed seems to be a novel effort and the authors deserve appreciation in this endeavour. (Source: Surgery)
Source: Surgery - November 5, 2018 Category: Surgery Authors: Suneel Mattoo, Amit Agarwal, Sabaretnam Mayilvaganan, Gaurav Agarwal, Anjali Mishra, Saroj K. Mishra, Gyan Chand Source Type: research

Validation of a novel patient-reported outcome measure for parathyroid and thyroid disease (PROMPT)
Patient-reported outcome measures are being used increasingly to assess disease severity and response to surgery. The purpose of this study was to create and validate a patient-reported outcome measure for symptoms of thyroid enlargement and hyperparathyroidism, 2 conditions where the presence of preoperative symptoms and response to surgery is often questioned. (Source: Surgery)
Source: Surgery - November 3, 2018 Category: Surgery Authors: Talia Burneikis, Jennifer Colvin, Judy Jin, Eren Berber, Vikram D Krishnamurthy, Joyce Shin, Allan Siperstein Source Type: research

Genetic characterization of medullary thyroid cancer in childhood survivors of the Chernobyl accident
Radiation-associated fusion oncogenes play a direct role in papillary thyroid cancer development and pathogenic fusions have recently been reported in medullary thyroid cancer. To date, no studies have evaluated oncogenic events in medullary thyroid cancer in a radiation-exposed population. (Source: Surgery)
Source: Surgery - November 1, 2018 Category: Surgery Authors: Sarah B. Fisher, Gilbert J. Cote, Jacquelin H. Bui-Griffith, Wei Lu, Ximing Tang, Tao Hai, Kevin E. Fisher, Michelle D. Williams, Ignacio I. Wistuba, Steven G. Waguespack, Clark M. Dorman, Michelle S. Ludwig, Paul H. Graham, Nancy D. Perrier, Jeffrey E. L Source Type: research

A propensity-matched analysis of clinical outcomes between open thyroid lobectomy and high-intensity focused ultrasound (HIFU) ablation of benign thyroid nodules
High-intensity focused ultrasound is a promising, nonoperative treatment for benign thyroid nodules. Our study aimed to compare treatment outcomes of single-session high-intensity focused ultrasound ablation with open lobectomy after propensity score matching. (Source: Surgery)
Source: Surgery - November 1, 2018 Category: Surgery Authors: Brian H.H. Lang, Carlos K.H. Wong, Estella P.M. Ma, Yu-Cho Woo, Keith Wan-Hang Chiu Source Type: research

A challenge to the world of health sciences research and others
The exponential growth of health sciences research has allowed many new avenues of investigation through the queries of large datasets. These studies serve as a reflection of the real world of outcomes, in contrast to the highly artificial, tightly controlled, randomized controlled trial conducted at a single center or the multicenter trials conducted in academic referral centers. Indeed, the studies of large, statewide or national databases, although they have their limitations, serve as an important mirror of the real world —and herein lies their strength. (Source: Surgery)
Source: Surgery - November 1, 2018 Category: Surgery Authors: Michael G. Sarr, Kevin E. Behrns Source Type: research

Does caudate lobe resection really not improve the survival and outcomes in patients with hilar cholangiocarcinoma?
We read with interest the recent publication by Bhutiani et al.1 which presents a large, retrospective, nonrandomized, multi-institutional series of 256 patients with hilar cholangiocarcinoma (HCCA) conducted from January 1, 2000 to May 30, 2015. They suggested that although caudate resection is associated with a greater likelihood of margin-negative resection (R0) in patients with extrahepatic hilar cholangiocarcinoma, the addition of caudate lobe resection did not increase overall survival (OS) or disease-free survival; caudate lobe resection may have improved disease-specific survival (DSS), particularly in patients who...
Source: Surgery - October 31, 2018 Category: Surgery Authors: Wen-Jie Ma, Fu-Yu Li, Nan-sheng Cheng Source Type: research

Databases for surgical health services research: Scientific Registry for Transplant Recipients
As electronic medical records become more prevalent and public reporting of outcomes increases in scope, a new challenge has emerged for researchers: exponential growth of data. The sheer volume of information makes navigating the array of available databases both time consuming and complicated for the busy clinician. Surgeons want to know how each source of data can be used effectively to answer their clinical and research-related questions. In this series, Surgery will explore examples of the most common databases used for surgical health services research —highlighting the strengths, limitations, and most effectiv...
Source: Surgery - October 30, 2018 Category: Surgery Authors: John R. Montgomery, Amit K. Mathur, Raymond J. Lynch Source Type: research

Gestational gigantomastia
A 31-year-old woman gravida 5 para 4, 18 weeks pregnant, presented to our emergency department with rapid bilateral breast enlargement over a 3-month period, with associated erythema and pain (Fig.  1). She had completed a course of antibiotics, prescribed by her primary care physician, but the breast erythema persisted. Magnetic resonance imaging demonstrated thickening and generalized edema or hyperemia of skin overlying the breasts (Fig. 2). Full thickness skin biopsies showed chronic der mal inflammation without evidence of malignancy. (Source: Surgery)
Source: Surgery - October 30, 2018 Category: Surgery Authors: Claire D. Gerall, Ismail Jatoi Source Type: research

The contemporary appendectomy for acute uncomplicated appendicitis in adults
Epidemiologic data related to the surgical management of appendicitis are out of date. As we contemplate the role of nonoperative therapy in uncomplicated appendicitis, a contemporary profile of the risks and benefits of operative appendectomy is needed. (Source: Surgery)
Source: Surgery - October 29, 2018 Category: Surgery Authors: Christopher P. Childers, Jill Q. Dworsky, Melinda Maggard-Gibbons, Marcia M. Russell Source Type: research

Is contralateral prophylactic mastectomy for unilateral breast cancer associated with higher complication rates and an increased hospital stay?
I recently read with interest the article by Dr Huang et al.1 This retrospective study compared the complications between patients with unilateral breast cancer who underwent contralateral prophylactic mastectomy (CPM) with those who underwent unilateral mastectomy and concluded that CPM was associated with a greater hospital stay but not related to a greater reoperation rate for complications. I would like to raise the following comments. (Source: Surgery)
Source: Surgery - October 29, 2018 Category: Surgery Authors: Gang Chen Source Type: research

Comments on: Cost-effectiveness of immediate biopsy versus surveillance of intermediate-suspicion thyroid nodules
We read with interest the article by Eric J Kuo, et al1 on cost-effectiveness of immediate biopsy versus surveillance of intermediate-suspicion thyroid nodules. We are also in favour of a noninvasive diagnostic test without compromising the accuracy of the test. The American Thyroid Association (ATA) currently recommends fine needle aspiration cytology (FNAC) for ATA intermediate-suspicion nodules ≥1.0 cm because these nodules harbour a 10% to 20% risk of malignancy.2 That means if we execute FNAC, we shall diagnose malignancy in 10% to 20% cases with intermediate suspicion on ultrasonography (USG). (Source: Surgery)
Source: Surgery - October 29, 2018 Category: Surgery Authors: Sarada Khadka, Kavindra Singh, Chitresh Kumar Source Type: research

Quality of reporting in randomized controlled trials of therapeutic cardiovascular medical devices
Therapeutic medical devices play an important role in the treatment of cardiovascular diseases. The reliability of the randomized controlled trial, which is the best design for assessing treatment effects, largely depends on the information found in published reports. Limited information regarding the quality of reporting about therapeutic medical devices in trials was provided. (Source: Surgery)
Source: Surgery - October 29, 2018 Category: Surgery Authors: Wenwen Chen, Jiajie Yu, Longhao Zhang, Guanyue Su, Wen Wang, Joey Kwong, Xin Sun, Youping Li Source Type: research

The definition of lymph node micrometastases in pathologic N1a papillary thyroid carcinoma should be revised
The aim of this study was to identify the risk factors for structural recurrence with a focus on lymph node –related factors and to determine the optimal cutoff size of lymph node micrometastases in patients with pathologic N1a classical papillary thyroid carcinoma. (Source: Surgery)
Source: Surgery - October 29, 2018 Category: Surgery Authors: Yu-Mi Lee, Jae Hyun Park, Jae Won Cho, Suck Joon Hong, Jong Ho Yoon Source Type: research

Re: Quality of life and symptom impact of thyroid cancer: A cross-sectional survey of Canadian patients
Goswami et al1 recently reported on quality of life impairments in thyroid cancer (TC) survivors. We also conducted a self-administered, mail-out survey of Canadian TC patients in an academic outpatient endocrinology clinic.2 One of the aims of our study to was to evaluate quality of life using the Thyroid Cancer module of the MD Anderson Symptom Inventory-Thyroid (MDASI-Thy).3 We specifically explored the severity of quality of life impairment and its interferences with life in this population. (Source: Surgery)
Source: Surgery - October 29, 2018 Category: Surgery Authors: Ahmad Alhashemi, Jennifer M. Jones, David P. Goldstein, Shereen Ezzat, Anna M. Sawka Source Type: research

Reply: Complications in unilateral breast cancer patients who undergo contralateral prophylactic mastectomy versus unilateral mastectomy
We thank Dr Chen for his insightful comments. Certainly, the technique of propensity score matching could be used to assess whether contralateral prophylactic mastectomy (CPM) is an independent predictor of increased complications, taking into account other factors that are different between this cohort of patients and their counterparts undergoing a unilateral mastectomy (UM). We chose not to do this because CPM was not associated with a difference in complication rate compared with patients undergoing UM; therefore, it would be unlikely that an effect would be muted by significant confounding (in opposite directions) by ...
Source: Surgery - October 29, 2018 Category: Surgery Authors: Julian Huang, Anees B. Chagpar Source Type: research

Response to Ja Cuoco
We acknowledge Dr Cuoco's na ïve “enthusiasm” for our work and for the many letters that he crafts on the heels of our publications on head transplants or spinal cord reconstruction, despite his lack of insight into all the crucial details. We take this opportunity to clarify the points he raises in the hopes that the medi cal community—after 5 years of discussion—may finally come around. (Source: Surgery)
Source: Surgery - October 29, 2018 Category: Surgery Authors: Xiaoping Ren Source Type: research

Epigenetic chromatin conformation changes in peripheral blood can detect thyroid cancer
Fine needle aspiration has been the traditional method for diagnosing thyroid cancer. Epigenetic chromatin conformation changes offer an alternative method of diagnosing cancer. The purpose of this study is to evaluate an EpiSwitch assay of epigenetic markers that can be used to diagnose thyroid cancer in blood samples. (Source: Surgery)
Source: Surgery - October 27, 2018 Category: Surgery Authors: Huan Yan, Ewan Hunter, Alexandre Akoulitchev, Patricia Park, David J Winchester, Tricia A Moo-Young, Richard A Prinz Source Type: research

Influence of carcinoid syndrome on the clinical characteristics and outcomes of patients with gastroenteropancreatic neuroendocrine tumors undergoing operative resection
The incidence, clinical characteristics, and long-term outcomes of patients with gastroenteropancreatic neuroendrocrine tumors and carcinoid syndrome undergoing operative resection have not been well characterized. (Source: Surgery)
Source: Surgery - October 27, 2018 Category: Surgery Authors: Charles W. Kimbrough, Eliza W. Beal, Mary E. Dillhoff, Carl R. Schmidt, Timothy M. Pawlik, Alexandra G. Lopez-Aguiar, George Poultsides, Eleftherios Makris, Flavio G. Rocha, Angelena Crown, Daniel E. Abbott, Alexander V. Fisher, Ryan C. Fields, Bradley A. Source Type: research

Comments on: Effect of wound massage on neck discomfort and voice changes after thyroidectomy
We read the article “Effect of wound massage on neck discomfort and voice changes after thyroidectomy”1 with great interest. The efforts of the authors to find a simple solution to a problem of great concern to both surgeons and patients are commendable. However, we have queries that we wish to put forward. (Source: Surgery)
Source: Surgery - October 27, 2018 Category: Surgery Authors: Shreyamsa M, Sasi Mouli V, Kul Ranjan Singh, Pooja Ramakant, Anand Kumar Mishra Source Type: research

Surgery for perihilar cholangiocarcinoma in octogenarians
We would like to compliment Akashi et al on a thorough analysis regarding the outcomes of surgery for perihilar cholangiocarcinoma (PHC) from the viewpoint of age.1 The authors showed that the average age of patients who undergo surgery for PHC has increased over the last decades, a trend that will likely continue in our aging society, and therefore the outcomes of surgery in older patients are of major interest. The authors show that surgery for PHC in octogenarians is feasible with similar morbidity and mortality as compared with younger age groups. (Source: Surgery)
Source: Surgery - October 27, 2018 Category: Surgery Authors: Pim B. Olthof, Thomas M. van Gulik Source Type: research

Re: Cost-effectiveness of immediate biopsy versus surveillance of intermediate-suspicion thyroid nodules
In their recent paper, Kuo et al.1 found that ultrasound surveillance was more cost-effective than immediate fine needle aspiration for 1.0 cm thyroid nodules classified as intermediate-suspicion based on the 2015 American Thyroid Association (ATA) guidelines.2 The authors wrote that Thyroid Imaging, Reporting and Data System (TIRADS), which offers an alternative approach to nodule management, is points-based and recommends 2.5 cm and 1.5 cm size cutoffs for aspiration of mildly and moderately suspicious nodules, respectively. (Source: Surgery)
Source: Surgery - October 26, 2018 Category: Surgery Authors: Franklin N. Tessler, William D. Middleton, Edward G. Grant, Jenny K. Hoang Source Type: research

Third-generation cephalosporin for antimicrobial prophylaxis in pancreatoduodenectomy in patients with internal preoperative biliary drainage
The aim of the present study was to investigate whether the incidence of surgical site infection after pancreatoduodenectomy decreased after changing the prophylactic antibiotic to a third-generation cephalosporin in patients with unknown preoperative bile culture results after biliary drainage. (Source: Surgery)
Source: Surgery - October 26, 2018 Category: Surgery Authors: Shusei Sano, Teiichi Sugiura, Ichiro Kawamura, Yukiyasu Okamura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi, Hanako Kurai, Katsuhiko Uesaka Source Type: research