Hypertrophic Obstructive Cardiomyopathy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Po-02-208 characterization of atrial electrophysiological properties in patients with hypertrophic obstructive cardiomyopathy
Atrial fibrillation (AF) occurs frequently in patients with hypertrophic obstructive cardiomyopathy (HOCM) and the success rate of pulmonary vein isolation in these patients is less effective compared to other populations. This may be explained by the presence of an extensive arrhythmogenic substrate in both atria due to a primary atrial myopathy, but electrophysiological properties of the right (RA) and left atrium (LA) have never been investigated. (Source: Heart Rhythm)
Source: Heart Rhythm - May 1, 2023 Category: Cardiology Authors: Nawin Ramdat Misier, Yannick Taverne, Jorik Amesz, Rohit K. Kharbanda, Hoang H. Nguyen, Mathijs S. van Schie, Paulus Knops, Peter L. de Jong, Bianca Brundel, Natasja M. De Groot Source Type: research

P13 Trametinib for chylothorax management in Noonan syndrome: discussion about efficacy, safety and tolerability
In conclusion, our experience has demonstrated that it is possible to manage the side effects of trametinib in a patient with multiple comorbidities using a patient centred and MDT approach. References Roberts AE, Allanson JE, Tartaglia M, Gelb BD. Noonan syndrome. Lancet 2013;381(9863):333–342. Dori Y, Smith C, Pinto E, Snyder K, March ME, Hakonarson H, Belasco J. Severe lymphatic disorder resolved with MEK inhibition in a patient with Noonan syndrome and SOS1 mutation. Pediatrics 2020;146(6):e20200167. doi: 10.1542/peds.2020-0167. PMID: 33219052. O’Hare P, Ahmed M, Samrin-Balch L. Guideline for the prescri...
Source: Archives of Disease in Childhood - April 19, 2023 Category: Pediatrics Authors: Brooks, T., Whiteley, S., Morris, S., Dunlop-Jones, A., Hribernik, I., Bentham, J. Tags: Abstract from the Neonatal and Paediatric Pharmacists Conference 2022 Source Type: research

A Narrative Review of Emerging Therapies for Hypertrophic Obstructive Cardiomyopathy
Curr Cardiol Rev. 2023 Mar 24. doi: 10.2174/1573403X19666230324102828. Online ahead of print.ABSTRACTHypertrophic obstructive cardiomyopathy is a hereditary condition that affects myocardial contraction. In case of failure of pharmacological treatment, alternative approaches might be used that include surgical myectomy, percutaneous transluminal septal myocardial ablation, and radiofrequency ablation. In respect of long-term advantages, surgical septal myectomy remains the therapy of choice for symptomatic hypertrophic obstructive cardiomyopathy. Alcohol septal ablation has been considered an alternative to surgical myecto...
Source: Current Cardiology Reviews - March 31, 2023 Category: Cardiology Authors: Antonio da Silva Menezes Junior Ana Ligia Valeriano de Oliveira Thais Aratak Marques Taia Silvia Mar çal Botelho Source Type: research

Is There a Role for Alcohol Septal Ablation in Young Patients with Medically Refractory Hypertrophic Obstructive Cardiomyopathy?
AbstractSurgical myectomy is recommended for symptomatic hypertrophic obstructive cardiomyopathy (HOCM) after optimal pharmacological therapy. Percutaneous transluminal septal myocardial ablation (PTSMA) is reserved for high-risk adults. Symptomatic patients below 25 years underwent either surgery or PTSMA after heart-team discussion and informed consent. Echocardiography assessed gradients in surgical group. PTSMA group underwent invasive transseptal hemodynamic assessment, selective coronary angiography and super-selective cannulation of septal perforators u sing microcatheters. Contrast echocardiography through the mi...
Source: Mammalian Genome - March 30, 2023 Category: Genetics & Stem Cells Source Type: research

Del nido versus conventional blood cardioplegia in patients with obstructive hypertrophic cardiomyopathy
CONCLUSIONS: The use of DNC in extended surgical myectomy procedure was as safe and effective as CBC. However, DNC infusion interval over 60 minutes was associated with increased postoperative CK-MB levels.PMID:36921566 | DOI:10.1177/02676591231163270 (Source: Perfusion)
Source: Perfusion - March 15, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Yingshan Huang Shujie Yan Yi Song Xiaoqi Wang Ke Yang Ling Zhang Wenting Gui Jiao Wang Yunling Yang Yan Xie Dongmei Wang Xinyue Li Source Type: research

Therapeutic Strategy for Patients with Concomitant Pulmonary Artery Hypertension and Hypertrophic Obstructive Cardiomyopathy: A Rare Case Report
Medicina (Kaunas). 2023 Feb 18;59(2):401. doi: 10.3390/medicina59020401.ABSTRACTCombined cases of hypertrophic obstructive cardiomyopathy (HOCM) and pulmonary arterial hypertension (PAH) are rare and have a management dilemma. Although preload is crucial in the management of HOCM, anti-PAH agents dramatically change the preload, leading to improving or worsening heart failure in patients with HOCM. We had a 74-year-old woman with Sjogren-syndrome-associated PAH. Her heart failure worsened following the initiation of anti-PAH agents due to an incremental preload on the left ventricle, whereas HOCM clinically developed follo...
Source: Medicina (Kaunas) - February 25, 2023 Category: Universities & Medical Training Authors: Toshihide Izumida Teruhiko Imamura Shuhei Tanaka Shuji Joho Koichiro Kinugawa Source Type: research