LB1676 Hibiscus sabdariffa-derived peptide, Gly-Pro (GP) has potent antifibrotic effects by regulating the serine-glycine biosynthesis pathway
In this study, we synthesized dipeptides containing proline derived from Hibiscus sabdariffa plant cells and evaluated their effect on collagen synthesis. (Source: Journal of Investigative Dermatology)
Source: Journal of Investigative Dermatology - August 21, 2023 Category: Dermatology Authors: H. Kim, Y. Jang, D. Seo, S. Lee, S. Moh, S. Choi, L. Germain, D. Kim, J. Shin Source Type: research
LB1793 Hibiscus-derived peptide, Tyr-Pro (YP) promotes human keratinocyte migration by activating FAK/ERK/MAPK signaling pathway
Background: Wound healing is a process of that repairs damaged or lost tissue, and the migration of epithelial cells is essential for restoring the skin barrier function. Although Hibiscus sabdariffa extract has been reported to enhance wound healing process, the exact mechanism has not been elucidated yet. Objective: In this paper, we evaluated the effect of tyrosine-proline (YP), a dipeptide identified from Hibiscus sabdariffa plant cells, on keratinocyte migration. Method: YP, one of the dipeptide derived from Hibiscus sabdariffa plant cells, was synthesized using the solid phase peptide synthesis method. (Source: Journ...
Source: Journal of Investigative Dermatology - August 21, 2023 Category: Dermatology Authors: D. Seo, Y. Jang, H. Kim, S. Lee, S. Moh, S. Choi, L. Germain, D. Kim, J. Shin Source Type: research
Inulin as prebiotic encapsulating agent for the production of spray-dried < em > Hibiscus sabdariffa < /em > L. tea microcapsules
Nat Prod Res. 2023 Aug 10:1-10. doi: 10.1080/14786419.2023.2244133. Online ahead of print.ABSTRACTDue to the high content of phenolics and anthocyanins of Hibiscus sabdariffa L. tea and the sensibility of these bioactive compounds, this work aimed to optimize the obtention of microcapsules by spray-drying, using inulin as a carrier agent. Using a Box-Behnken Design, the effects of inlet temperature (130, 150, and 170 °C), feed flow rate (5, 10, and 15 mL min-1), and inulin concentration (5, 10, and 15 g L-1) were evaluated. It was possible to obtain pale-rose, slightly sweet instant powders with good total polyphenol cont...
Source: Natural Product Research - August 16, 2023 Category: Biochemistry Authors: Caroline Maria Calliari Marianne Ayumi Shirai Alessandro Alberto Casazza Margherita Pettinato Patrizia Perego Source Type: research
Hibiscus rosa-sinensis as a potential hyperaccumulator in metal contaminated magnesite mine tailings
In this study, the physicochemical properties of magnesite mine soil was investigated and assess the optimistic and eco-friendly remediation approach with Hibiscus rosa-sinensis with the effect of pre-isolated Acidithiobacillus thiooxidans. The physicochemical properties analysis results revealed that most the parameter were either too less or beyond the permissible limits. The pre-isolated A. thiooxidans showed remarkable multi-metal tolerance up to 800μg mL-1 concentration of Cr, Cd, Pb, and Mn. Heavy metal content in polluted soil was reduced to avoid more metal toxicity by diluting with fertile control soil as 80:20 a...
Source: Chemosphere - August 6, 2023 Category: Chemistry Authors: Nguyen Chi Thanh Mathiyazhagan Narayanan Mythili Saravanan Arunachalam Chinnathambi Tahani Awad Alahmadi Kathirvel Brindhadevi Ashutosh Sharma Arivalagan Pugazhendhi Source Type: research
Hibiscus rosa-sinensis as a potential hyperaccumulator in metal contaminated magnesite mine tailings
In this study, the physicochemical properties of magnesite mine soil was investigated and assess the optimistic and eco-friendly remediation approach with Hibiscus rosa-sinensis with the effect of pre-isolated Acidithiobacillus thiooxidans. The physicochemical properties analysis results revealed that most the parameter were either too less or beyond the permissible limits. The pre-isolated A. thiooxidans showed remarkable multi-metal tolerance up to 800μg mL-1 concentration of Cr, Cd, Pb, and Mn. Heavy metal content in polluted soil was reduced to avoid more metal toxicity by diluting with fertile control soil as 80:20 a...
Source: Chemosphere - August 6, 2023 Category: Chemistry Authors: Nguyen Chi Thanh Mathiyazhagan Narayanan Mythili Saravanan Arunachalam Chinnathambi Tahani Awad Alahmadi Kathirvel Brindhadevi Ashutosh Sharma Arivalagan Pugazhendhi Source Type: research
Hibiscus rosa-sinensis as a potential hyperaccumulator in metal contaminated magnesite mine tailings
In this study, the physicochemical properties of magnesite mine soil was investigated and assess the optimistic and eco-friendly remediation approach with Hibiscus rosa-sinensis with the effect of pre-isolated Acidithiobacillus thiooxidans. The physicochemical properties analysis results revealed that most the parameter were either too less or beyond the permissible limits. The pre-isolated A. thiooxidans showed remarkable multi-metal tolerance up to 800μg mL-1 concentration of Cr, Cd, Pb, and Mn. Heavy metal content in polluted soil was reduced to avoid more metal toxicity by diluting with fertile control soil as 80:20 a...
Source: Chemosphere - August 6, 2023 Category: Chemistry Authors: Nguyen Chi Thanh Mathiyazhagan Narayanan Mythili Saravanan Arunachalam Chinnathambi Tahani Awad Alahmadi Kathirvel Brindhadevi Ashutosh Sharma Arivalagan Pugazhendhi Source Type: research
Hibiscus rosa-sinensis as a potential hyperaccumulator in metal contaminated magnesite mine tailings
In this study, the physicochemical properties of magnesite mine soil was investigated and assess the optimistic and eco-friendly remediation approach with Hibiscus rosa-sinensis with the effect of pre-isolated Acidithiobacillus thiooxidans. The physicochemical properties analysis results revealed that most the parameter were either too less or beyond the permissible limits. The pre-isolated A. thiooxidans showed remarkable multi-metal tolerance up to 800μg mL-1 concentration of Cr, Cd, Pb, and Mn. Heavy metal content in polluted soil was reduced to avoid more metal toxicity by diluting with fertile control soil as 80:20 a...
Source: Chemosphere - August 6, 2023 Category: Chemistry Authors: Nguyen Chi Thanh Mathiyazhagan Narayanan Mythili Saravanan Arunachalam Chinnathambi Tahani Awad Alahmadi Kathirvel Brindhadevi Ashutosh Sharma Arivalagan Pugazhendhi Source Type: research
Comparison of healthcare costs before and after a STEMI: A French national health data system-based cohort study
CONCLUSIONS: This study shows a significant surplus (threefold) of healthcare resource consumption in the year following a STEMI compared to the year preceding the STEMI.PMID:37524298 | DOI:10.1016/j.jjcc.2023.07.010 (Source: Journal of Cardiology)
Source: Journal of Cardiology - July 31, 2023 Category: Cardiology Authors: Hassan Serrier Hugo Rabier Violaine Fernandez Anne-Marie Schott Nathan Mewton Michel Ovize Norbert Nighoghossian Antoine Duclos Cyrille Colin Source Type: research
Comparison of healthcare costs before and after a STEMI: A French national health data system-based cohort study
CONCLUSIONS: This study shows a significant surplus (threefold) of healthcare resource consumption in the year following a STEMI compared to the year preceding the STEMI.PMID:37524298 | DOI:10.1016/j.jjcc.2023.07.010 (Source: Journal of Cardiology)
Source: Journal of Cardiology - July 31, 2023 Category: Cardiology Authors: Hassan Serrier Hugo Rabier Violaine Fernandez Anne-Marie Schott Nathan Mewton Michel Ovize Norbert Nighoghossian Antoine Duclos Cyrille Colin Source Type: research
Comparison of healthcare costs before and after a STEMI: A French national health data system-based cohort study
CONCLUSIONS: This study shows a significant surplus (threefold) of healthcare resource consumption in the year following a STEMI compared to the year preceding the STEMI.PMID:37524298 | DOI:10.1016/j.jjcc.2023.07.010 (Source: Journal of Cardiology)
Source: Journal of Cardiology - July 31, 2023 Category: Cardiology Authors: Hassan Serrier Hugo Rabier Violaine Fernandez Anne-Marie Schott Nathan Mewton Michel Ovize Norbert Nighoghossian Antoine Duclos Cyrille Colin Source Type: research
Comparison of healthcare costs before and after a STEMI: A French national health data system-based cohort study
CONCLUSIONS: This study shows a significant surplus (threefold) of healthcare resource consumption in the year following a STEMI compared to the year preceding the STEMI.PMID:37524298 | DOI:10.1016/j.jjcc.2023.07.010 (Source: Journal of Cardiology)
Source: Journal of Cardiology - July 31, 2023 Category: Cardiology Authors: Hassan Serrier Hugo Rabier Violaine Fernandez Anne-Marie Schott Nathan Mewton Michel Ovize Norbert Nighoghossian Antoine Duclos Cyrille Colin Source Type: research
Intercropping of kenaf and soybean affects plant growth, antioxidant capacity, and uptake of cadmium and lead in contaminated mining soil
Environ Sci Pollut Res Int. 2023 Jul 16. doi: 10.1007/s11356-023-28757-6. Online ahead of print.ABSTRACTIntercropping is considered a sustainable agricultural practice that can reduce the environmental impacts on agriculture. Our study investigated the morphology, physiology, and cadmium (Cd) and lead (Pb) uptake of kenaf (Hibiscus cannabinus L.) and soybean (Glycine max L.) under intercropping in mining soil. Results showed that mutual intercropping is conducive to the growth and biomass accumulation of kenaf and soybean, compared to their respective monoculture. Intercropping increased the relative chlorophyll index in k...
Source: Environmental Science and Pollution Research International - July 16, 2023 Category: Environmental Health Authors: Muzammal Rehman Jiao Pan Samavia Mubeen Wenyue Ma Dengjie Luo Shan Cao Peng Chen Source Type: research
Intercropping of kenaf and soybean affects plant growth, antioxidant capacity, and uptake of cadmium and lead in contaminated mining soil
Environ Sci Pollut Res Int. 2023 Jul 16. doi: 10.1007/s11356-023-28757-6. Online ahead of print.ABSTRACTIntercropping is considered a sustainable agricultural practice that can reduce the environmental impacts on agriculture. Our study investigated the morphology, physiology, and cadmium (Cd) and lead (Pb) uptake of kenaf (Hibiscus cannabinus L.) and soybean (Glycine max L.) under intercropping in mining soil. Results showed that mutual intercropping is conducive to the growth and biomass accumulation of kenaf and soybean, compared to their respective monoculture. Intercropping increased the relative chlorophyll index in k...
Source: Environmental Science and Pollution Research International - July 16, 2023 Category: Environmental Health Authors: Muzammal Rehman Jiao Pan Samavia Mubeen Wenyue Ma Dengjie Luo Shan Cao Peng Chen Source Type: research
Hibiscus-cisplatin combination treatment decreases liver toxicity in rats while increasing toxicity in lung cancer cells via oxidative stress- apoptosis pathway
Biomed Pharmacother. 2023 Jul 12;165:115148. doi: 10.1016/j.biopha.2023.115148. Online ahead of print.ABSTRACTCisplatin (CIS) is a broad-spectrum anti-carcinogen that causes cytotoxic effects both in normal and cancer cells. The purpose of this study was to test whether Hibiscus sabdariffa (HS) extract can reduce CIS-induced hepatotoxicity in rodents and to assess its anticancer activity in vitro. Treatment with HS extract at daily doses of 500 mg/kg before and after a single dose of CIS (10 mg/kg) reduced hepatotoxicity in Wistar male albino rats. HS extract reduced activity of hepatic damage marker enzymes ( i.e. alanine...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 14, 2023 Category: Drugs & Pharmacology Authors: Alaaeldin Ahmed Hamza Gehan Hussein Heeba Soha Osama Hassanin Hanan Mohamed Elwy Amany Abdelrehim Bekhit Amr Amin Source Type: research
Hibiscus-cisplatin combination treatment decreases liver toxicity in rats while increasing toxicity in lung cancer cells via oxidative stress- apoptosis pathway
Biomed Pharmacother. 2023 Jul 12;165:115148. doi: 10.1016/j.biopha.2023.115148. Online ahead of print.ABSTRACTCisplatin (CIS) is a broad-spectrum anti-carcinogen that causes cytotoxic effects both in normal and cancer cells. The purpose of this study was to test whether Hibiscus sabdariffa (HS) extract can reduce CIS-induced hepatotoxicity in rodents and to assess its anticancer activity in vitro. Treatment with HS extract at daily doses of 500 mg/kg before and after a single dose of CIS (10 mg/kg) reduced hepatotoxicity in Wistar male albino rats. HS extract reduced activity of hepatic damage marker enzymes ( i.e. alanine...
Source: Cancer Control - July 14, 2023 Category: Cancer & Oncology Authors: Alaaeldin Ahmed Hamza Gehan Hussein Heeba Soha Osama Hassanin Hanan Mohamed Elwy Amany Abdelrehim Bekhit Amr Amin Source Type: research
