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Antimicrobial constituents from the leaves of Hibiscus tiliaceus L
Nat Prod Res. 2023 Dec 12:1-8. doi: 10.1080/14786419.2023.2293137. Online ahead of print.ABSTRACTRepeated column chromatography resulted in the isolation of two new megastigmane derivatives, methyl-tiliaceates A and B (1 and 2), along with four known metabolites (3-6) from the leaves of Hibiscus tiliaceus L. The structures of the purified phytochemicals were elucidated by interpreting their NMR, HRESIMS, and CD spectroscopic data, as well as comparison with the previous literature. The compounds isolated were subjected to in vitro antimicrobial assays against a panel of pathogenic microorganisms (Enterococcus faecalis, Sta...
Source: Natural Product Research - December 12, 2023 Category: Biochemistry Authors: Vu Thanh Trung Kieu Thi Phuong Linh Duong Thu Trang Pham Thanh Binh Nguyen The Cuong Nguyen Van Thanh Nguyen Xuan Cuong Nguyen Hoai Nam Nguyen Phuong Thao Source Type: research

Exploring the interaction of phytochemicals from Hibiscus rosa-sinensis flowers with glucosidase and acetylcholinesterase: An integrated in vitro and in silico approach
Comput Biol Chem. 2023 Dec 1;108:107996. doi: 10.1016/j.compbiolchem.2023.107996. Online ahead of print.ABSTRACTTargeting multiple factors such as oxidative stress, alpha glucosidase and acetylcholinesterase (AChE) are considered advantageous for the treatment of diabetes and diabetes associated-cognitive dysfunction. In the present study, Hibiscus rosa-sinensis flowers anthocyanin-rich extract (HRA) was prepared. Phytochemical analysis of HRA using LC-ESI/MS/MS revealed the presence of various phenolic acids, flavonoids and anthocyanins. HRA showed in vitro antioxidant activity at low concentrations. HRA inhibited all the...
Source: Computational Biology and Chemistry - December 7, 2023 Category: Bioinformatics Authors: Chitra Loganathan Fuad Ameen Penislusshiyan Sakayanathan M Amirul Islam Palvannan Thayumanavan Source Type: research

Characterisation analysis of bio oil generation using Hibiscus cannabinus seeds
Nat Prod Res. 2023 Sep 23:1-9. doi: 10.1080/14786419.2023.2261142. Online ahead of print.ABSTRACTBio-oil from Hibiscus cannabinus seeds was extracted with four solvents: acetone, benzene, isopropanol, and hexane. Solvent extraction techniques have less oil residue than other methods. The primary factors that influence the extraction processes such as extraction time, particle size, seed ageing, and solvent suitability were optimised to enhance the bio-oil yield. The extracted bio-oil was tested by GC-MS, FTIR, and 1H-NMR. Physicochemical properties (free fatty acid, specific gravity, acid value, calorific value, saponifica...
Source: Natural Product Research - September 23, 2023 Category: Biochemistry Authors: Govindhan P Source Type: research

Chemical profile of Roselle extract and its inhibitory activities on three digestive enzymes in vitro and in vivo
Int J Biol Macromol. 2023 Sep 13:126902. doi: 10.1016/j.ijbiomac.2023.126902. Online ahead of print.ABSTRACTRoselle is rich in an extensive diversity of beneficial substances, including phenolic acids, amino acids, anthocyanins, vitamins, and flavonoids. Herein, the chemical constituents in Roselle extract (RE) were identified by UPLC-DAD-QTOF-MS. Besides, its inhibitory effects on three digestive enzymes, i.e. α-amylase, α-glucosidase, and pancreatic lipase, were investigated in both in vitro and in vivo. Thirty-three constituents including hibiscus acid, 18 phenolic acids, 2 anthocyanins and 12 flavonoids were identifi...
Source: International Journal of Biological Macromolecules - September 15, 2023 Category: Biochemistry Authors: Dan Yang Xin-Yu-Yao Ding Hai-Xia Xu Yu-Xian Guo Qing-Feng Zhang Source Type: research

Chemical profile of Roselle extract and its inhibitory activities on three digestive enzymes in vitro and in vivo
Int J Biol Macromol. 2023 Sep 14;253(Pt 3):126902. doi: 10.1016/j.ijbiomac.2023.126902. Online ahead of print.ABSTRACTRoselle is rich in an extensive diversity of beneficial substances, including phenolic acids, amino acids, anthocyanins, vitamins, and flavonoids. Herein, the chemical constituents in Roselle extract (RE) were identified by UPLC-DAD-QTOF-MS. Besides, its inhibitory effects on three digestive enzymes, i.e. α-amylase, α-glucosidase, and pancreatic lipase, were investigated in both in vitro and in vivo. Thirty-three constituents including hibiscus acid, 18 phenolic acids, 2 anthocyanins and 12 flavonoids wer...
Source: International Journal of Biological Macromolecules - September 15, 2023 Category: Biochemistry Authors: Dan Yang Xin-Yu-Yao Ding Hai-Xia Xu Yu-Xian Guo Qing-Feng Zhang Source Type: research

Antibacterial activity of hexane and methanol fractions of some selected plants against Klebsiella pneumoniae 
This study, therefore, investigated the antibacterial activity of some selected plants (Pandanus tectorius, Nypa fruticans, Sonneratia alba, Phaleria macrocarpa, Hibiscus tiliaceus, and Pongamia pinnata) against K. pneumoniae. In this study, samples were extracted successively by cold maceration using hexane and methanol. Antibacterial activity was determined by well and disc diffusion methods. Each fraction was prepared by two-fold dilutions from 20 mg/mL to 0.156 mg/mL. All data were analyzed in triplicate replication and presented as mean values ± standard deviation. Results showed that all methanol fractions of select...
Source: Adv Data - September 11, 2023 Category: Epidemiology Authors: Yosie Andriani Wahdini Hanifah Alifa Husnun Kholieqoh Fadzilah Adibah Abdul Majid Hermansyah Hermansyah Hermansyah Amir Tengku Sifzizul Tengku Muhammad Source Type: research

Roots, Leaves, and Flowers: A Narrative Review of Herbs and Botanicals Used for Self ‐Managed Abortion in Asia and the Pacific
AbstractAbortion has existed throughout history, often outside of formal health care systems. This type of care, now called self-managed abortion, has historically been achieved in part through botanicals and traditional medicines. Their use continues into the modern day, especially in Asia, Hawai‘i, and other Pacific Islands, where indigenous medicine traditions practice alongside allopathic medicine. Many of these botanicals, such as papaya leaves, hibiscus flowers, and young k ī, and traditional medicines, such astianhuafen,yuanhua, andShenghua Decoction, have undergone scientific and clinical investigation of their ...
Source: Journal of Midwifery and Women's Health - September 6, 2023 Category: Midwifery Authors: Tracy X. Chen, April Hamachi, Reni Soon, Melissa Natavio Tags: Review Source Type: research